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Gene: Actg2 (actin gamma 2, smooth muscle) Rattus norvegicus

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Symbol:

Actg2

Name:

actin gamma 2, smooth muscle

RGD ID:

2027

Description:

Predicted to enable ATP binding activity; hydrolase activity; and protein kinase binding activity. Predicted to be involved in mesenchyme migration and positive regulation of gene expression. Predicted to be located in several cellular components, including filopodium; lamellipodium; and myosin filament. Predicted to be part of protein-containing complex. Predicted to be active in actin cytoskeleton. Human ortholog(s) of this gene implicated in megacystis-microcolon-intestinal hypoperistalsis syndrome. Orthologous to human ACTG2 (actin gamma 2, smooth muscle); INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ACTGE; Actin gamma 2 smooth muscle enteric; actin, gamma 2; actin, gamma 2, smooth muscle, enteric; actin, gamma-enteric smooth muscle; alpha-actin-3; alpha-smooth muscle actin; gamma-2-actin; gamma-enteric smooth muscle actin; MGC105507; SMGA; smooth muscle gamma-actin

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ACTG2 (actin gamma 2, smooth muscle)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, Panther, PhylomeDB
Mus musculus (house mouse):	Actg2 (actin, gamma 2, smooth muscle, enteric)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Actg2 (actin gamma 2, smooth muscle)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ACTG2 (actin gamma 2, smooth muscle)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ACTG2 (actin gamma 2, smooth muscle)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Actg2 (actin gamma 2, smooth muscle)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ACTG2 (actin gamma 2, smooth muscle)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ACTG2 (actin gamma 2, smooth muscle)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Actg2 (actin gamma 2, smooth muscle)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Actg2 (actin, gamma 2, smooth muscle, enteric)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ACTG2 (actin gamma 2, smooth muscle)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ACT1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	acta2	Alliance	DIOPT (OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	117,579,513 - 117,604,379 (-)	NCBI		GRCr8
mRatBN7.2	4	116,021,832 - 116,046,475 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	116,021,832 - 116,046,465 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	121,500,276 - 121,514,993 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	117,275,441 - 117,290,158 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	115,889,059 - 115,903,778 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	115,215,160 - 115,239,746 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	115,215,060 - 115,239,723 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	179,805,782 - 179,830,362 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	117,732,482 - 117,747,006	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	105,015,569 - 105,030,100 (-)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant familial visceral neuropathy (ISO)

Colonic Neoplasms (ISO)

congenital disorder of glycosylation type IIb (ISO)

dystonia (ISO)

Familial Visceral Myopathy (ISO)

genetic disease (ISO)

intestinal obstruction (ISO)

intestinal pseudo-obstruction (ISO)

megacystis-microcolon-intestinal hypoperistalsis syndrome (ISO,ISS)

Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome 5 (ISO)

Megaduodenum (ISO)

Methylmalonyl-CoA Epimerase Deficiency (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (EXP,ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP,ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-nitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,7-dihydropurine-6-thione (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (EXP)

9-cis-retinoic acid (EXP)

acetamide (EXP)

all-trans-retinoic acid (EXP,ISO)

all-trans-retinol (EXP)

amitrole (EXP)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bromochloroacetic acid (EXP)

butanal (ISO)

cadmium acetate (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

calcitriol (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

carmustine (ISO)

chromium(6+) (ISO)

cocaine (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

corticosterone (EXP)

cyclosporin A (ISO)

DDT (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP,ISO)

diethylstilbestrol (EXP,ISO)

dioxygen (EXP)

diuron (EXP)

doramapimod (EXP)

dorsomorphin (ISO)

ethanol (EXP)

fipronil (EXP)

folic acid (ISO)

genistein (ISO)

glyphosate (ISO)

Heliotrine (EXP)

hyaluronic acid (EXP)

hydrogen peroxide (EXP)

isoprenaline (ISO)

ketamine (EXP)

leflunomide (ISO)

lipopolysaccharide (ISO)

losartan (EXP)

mercaptopurine (EXP)

mercury dibromide (ISO)

methimazole (EXP)

methylmercury chloride (ISO)

methylseleninic acid (ISO)

mitoxantrone (ISO)

Monobutylphthalate (ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

nickel subsulfide (EXP)

nickel sulfate (ISO)

nitrofen (EXP)

paracetamol (ISO)

paraquat (EXP)

phenylmercury acetate (ISO)

PhIP (EXP)

pioglitazone (ISO)

pirinixic acid (ISO)

progesterone (ISO)

purine-6-thiol (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

senecionine (EXP)

serpentine asbestos (ISO)

silicon dioxide (EXP,ISO)

silver atom (ISO)

silver(0) (ISO)

sodium fluoride (ISO)

sorafenib (EXP)

succimer (ISO)

sulforaphane (ISO)

temozolomide (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

thymoquinone (EXP)

titanium dioxide (EXP)

topotecan (ISO)

triadimefon (ISO)

trichloroethene (EXP)

valproic acid (ISO)

XL147 (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

glomerular mesangial cell development (IEA)

mesenchyme migration (ISS)

positive regulation of gene expression (ISS)

regulation of blood pressure (IEA)

response to virus (IEA)

vascular associated smooth muscle contraction (IEA)

Cellular Component

actin cytoskeleton (IBA,IEA)

cell body (ISS)

cell periphery (IEA,ISO)

cytoplasm (IEA,ISS)

cytoskeleton (IEA)

filopodium (ISS)

lamellipodium (ISS)

motile cilium (IEA)

myosin filament (ISS)

protein-containing complex (IEA)

smooth muscle contractile fiber (IEA)

Molecular Function

ATP binding (IEA)

hydrolase activity (IEA)

nucleotide binding (IEA)

protein kinase binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	The development expression of the rat alpha-vascular and gamma-enteric smooth muscle isoactins: isolation and characterization of a rat gamma-enteric actin cDNA.	McHugh KM and Lessard JL, Mol Cell Biol 1988 Dec;8(12):5224-31.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	[Complex evaluation of the health status indicators of military personnel].	Poliakov LE, etal., Voen Med Zh. 1978 Nov;(11):15-20.
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Comprehensive gene review and curation	RGD comprehensive gene curation
11.	Tentative Sequence Identification Numbers	Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
12.	Polski tygodnik lekarski (Warsaw, Poland : 1960)	Woyton A Pol Tyg Lek 1978 Aug 7;33(32):1263-4.

Additional References at PubMed

PMID:3597426	PMID:12040017	PMID:12477932	PMID:12482893	PMID:15489334	PMID:15591055	PMID:15972885	PMID:16259921	PMID:16493181	PMID:16533564	PMID:19797053	PMID:22165288
PMID:22516433	PMID:23533145	PMID:23580065	PMID:25002582	PMID:29476059	PMID:31484043

Genomics

Comparative Map Data

Actg2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	117,579,513 - 117,604,379 (-)	NCBI		GRCr8
mRatBN7.2	4	116,021,832 - 116,046,475 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	116,021,832 - 116,046,465 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	121,500,276 - 121,514,993 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	117,275,441 - 117,290,158 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	115,889,059 - 115,903,778 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	115,215,160 - 115,239,746 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	115,215,060 - 115,239,723 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	179,805,782 - 179,830,362 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	117,732,482 - 117,747,006	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	105,015,569 - 105,030,100 (-)	NCBI		Celera
Cytogenetic Map	4	q34	NCBI

ACTG2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	73,893,008 - 73,919,865 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	73,892,314 - 73,919,865 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	74,120,135 - 74,146,992 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	73,973,601 - 74,000,288 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	74,031,789 - 74,058,434	NCBI
Celera	2	73,951,347 - 73,978,043 (+)	NCBI		Celera
Cytogenetic Map	2	p13.1	NCBI
HuRef	2	73,854,905 - 73,882,444 (+)	NCBI		HuRef
CHM1_1	2	74,049,434 - 74,076,040 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	73,901,172 - 73,928,327 (+)	NCBI		T2T-CHM13v2.0

Actg2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	83,489,891 - 83,513,233 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	83,489,887 - 83,513,247 (-)	Ensembl		GRCm39 Ensembl
GRCm38	6	83,512,909 - 83,536,251 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	83,512,905 - 83,536,265 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	83,462,903 - 83,486,245 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	83,478,568 - 83,501,883 (-)	NCBI		MGSCv36	mm8
Celera	6	85,494,063 - 85,517,393 (-)	NCBI		Celera
Cytogenetic Map	6	C3	NCBI
cM Map	6	35.94	NCBI

Actg2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955424	11,779,597 - 11,802,446 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955424	11,779,805 - 11,802,446 (-)	NCBI	ChiLan1.0	ChiLan1.0

ACTG2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	52,464,021 - 52,490,974 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	52,466,775 - 52,493,728 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	73,966,939 - 73,993,862 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	75,476,877 - 75,503,658 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	75,476,877 - 75,503,658 (+)	Ensembl	panpan1.1		panPan2

ACTG2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	49,144,184 - 49,168,872 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	49,104,546 - 49,168,782 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	48,784,850 - 48,810,117 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	50,003,715 - 50,028,411 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	50,003,722 - 50,028,328 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	49,019,875 - 49,044,569 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	49,087,331 - 49,111,998 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	49,645,142 - 49,670,439 (-)	NCBI		UU_Cfam_GSD_1.0

Actg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	10,517,808 - 10,563,374 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936556	174,602 - 220,285 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936556	174,602 - 220,088 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ACTG2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	69,096,782 - 69,121,351 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	69,097,366 - 69,121,542 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	72,251,872 - 72,257,786 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ACTG2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	33,363,170 - 33,390,710 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	33,363,023 - 33,390,937 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	78,776,828 - 78,804,281 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Actg2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624749	29,566,380 - 29,588,705 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624749	29,566,613 - 29,588,572 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Actg2
273 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	53
Count of miRNA genes:	51
Interacting mature miRNAs:	53
Transcripts:	ENSRNOT00000042699
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1582232	Gluco25	Glucose level QTL 25	3.6	0.0023	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	85253748	148090731	Rat
631689	Scl4	Serum cholesterol level QTL 4	1.9	0.008	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	4	95174120	140174120	Rat
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	38465774	146803430	Rat
1578655	Bmd11	Bone mineral density QTL 11	11		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	4	90850165	135850165	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	26775591	168368347	Rat
1357342	Bw40	Body weight QTL 40		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	4	76647384	117676292	Rat
631556	Bp135	Blood pressure QTL 135		0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	78881294	117676292	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	70362013	132642728	Rat
70167	Bw22	Body weight QTL 22	3.1		body mass (VT:0001259)	body weight (CMO:0000012)	4	76647384	117676292	Rat
731165	Uae21	Urinary albumin excretion QTL 21	2.4	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	4	106649412	151649412	Rat
737821	Hcar9	Hepatocarcinoma resistance QTL 9	3.7		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	109866907	167139601	Rat
1549832	Bss3	Bone structure and strength QTL 3	11		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	4	109827074	154827074	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	82798864	152731274	Rat
724522	Bp146	Blood pressure QTL 146	2.2	0.0021	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	73630210	118630210	Rat
61476	Aia3	Adjuvant induced arthritis QTL 3	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	86730991	131730991	Rat
1641919	Alc22	Alcohol consumption QTL 22		0.0005	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	81192555	126192555	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	44463908	148090542	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	50119848	146803430	Rat
1578670	Bss14	Bone structure and strength QTL 14	16.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	4	87327165	132327165	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	39524264	116179656	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	56647873	149491524	Rat
1331759	Hrtrt13	Heart rate QTL 13	3.54628		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	110275411	168266883	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
1578662	Bss15	Bone structure and strength QTL 15	19.6		femur width (VT:1000666)	femoral neck width (CMO:0001695)	4	87327165	132327165	Rat
2302051	Pia28	Pristane induced arthritis QTL 28	5.3	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)	4	73630210	118630210	Rat
2302049	Pia32	Pristane induced arthritis QTL 32	5.1	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)	4	105789505	150789505	Rat
6478763	Anxrr46	Anxiety related response QTL 46		0.07428	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	110870972	155870972	Rat
6478760	Anxrr45	Anxiety related response QTL 45		0.06717	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	110870972	155870972	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	59948935	154902892	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	0.006	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	4	45456990	146803430	Rat
738015	Pia9	Pristane induced arthritis QTL 9	4.5	0.048	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	80694870	125694870	Rat
7207480	Bss105	Bone structure and strength QTL 105	8.1		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	4	109827074	154827074	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	93308457	167139447	Rat
631646	Stl4	Serum triglyceride level QTL 4	6.5	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	4	73169846	132642728	Rat
634334	Xhs3	X-ray hypersensitivity QTL 3	10		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	84728680	129854654	Rat
61406	Scwia1	Streptococcal cell wall induced arthritis QTL 1	2.3		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	4	106805662	151805662	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	44463908	148090542	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5214602	146446691	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	83428419	177635233	Rat
631662	Hcar2	Hepatocarcinoma resistance QTL 2	3.1	0.0003	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	78878504	123878504	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	44463720	155883716	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	62277855	128289560	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	59948935	154902892	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	0.02	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	85379421	167139601	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	56698790	126192555	Rat
2306899	Bp338	Blood pressure QTL 338		0.071	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	81006124	120102625	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	64528739	157573521	Rat
12798519	Anxrr54	Anxiety related response QTL 54	2.54	0.05	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	114627026	159627026	Rat
12798523	Anxrr56	Anxiety related response QTL 56	2.83	0.05	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	85253748	150276390	Rat
61434	Cia3	Collagen induced arthritis QTL 3	4.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	103194656	148194656	Rat

Markers in Region

PMC20960P1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	11,665,621 - 11,665,967 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	13,718,353 - 13,718,698	NCBI	Rnor6.0
Rnor_5.0	12	15,748,366 - 15,748,711	UniSTS	Rnor5.0
RGSC_v3.4	12	12,049,580 - 12,049,925	UniSTS	RGSC3.4
Celera	12	13,454,953 - 13,455,298	UniSTS
Cytogenetic Map	12	p11	UniSTS
Cytogenetic Map	4	q34	UniSTS

STS_ADH2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	100,812,851 - 100,813,988 (+)	MAPPER	mRatBN7.2
mRatBN7.2	4	37,621,193 - 37,621,465 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	35,593,637 - 35,593,908	NCBI	Rnor6.0
Rnor_6.0	3	105,508,268 - 105,509,404	NCBI	Rnor6.0
Rnor_5.0	4	35,451,038 - 35,451,309	UniSTS	Rnor5.0
Rnor_5.0	3	112,081,718 - 112,082,854	UniSTS	Rnor5.0
RGSC_v3.4	3	99,901,887 - 99,903,023	UniSTS	RGSC3.4
RGSC_v3.4	4	34,652,200 - 34,652,471	UniSTS	RGSC3.4
Celera	4	33,105,107 - 33,105,378	UniSTS
Celera	3	99,782,375 - 99,783,511	UniSTS
Cytogenetic Map	3	q35	UniSTS
Cytogenetic Map	4	q21	UniSTS
Cytogenetic Map	4	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	111	91	90	59	25	59	6	218	97	91	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_012893	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236728	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC115473	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC087689	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473957	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ220823	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221094	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221892	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ223160	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ229904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M22323	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000042699 ⟹ ENSRNOP00000050322

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	116,021,832 - 116,046,465 (-)	Ensembl
Rnor_6.0 Ensembl	4	115,215,060 - 115,239,723 (-)	Ensembl

RefSeq Acc Id:

NM_012893 ⟹ NP_037025

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	117,579,513 - 117,594,039 (-)	NCBI
mRatBN7.2	4	116,021,832 - 116,036,358 (-)	NCBI
Rnor_6.0	4	115,215,160 - 115,229,684 (-)	NCBI
Rnor_5.0	4	179,805,782 - 179,830,362 (-)	NCBI
RGSC_v3.4	4	117,732,482 - 117,747,006 (-)	RGD
Celera	4	105,015,569 - 105,030,100 (-)	RGD

Sequence:

show sequence

TCCACCGCGCCCACCATGTGTGAAGAAGAGACCACCGCCCTTGTGTGTGACAATGGGTCTGGCC
TGTGCAAGGCAGGCTTTGCAGGAGACGACGCTCCCAGGGCTGTCTTTCCCTCCATTGTGGGCCG
CCCTCGGCATCAGGGCGTGATGGTGGGAATGGGCCAGAAAGACAGCTATGTGGGGGACGAAGCC
CAGAGCAAGCGTGGGATCCTGACCCTCAAATACCCCATTGAGCACGGCATCATCACGAACTGGG
ATGACATGGAGAAGATCTGGCACCACTCCTTCTACAACGAGCTGCGAGTAGCACCAGAAGAGCA
CCCGACCCTGCTCACAGAGGCCCCCCTAAACCCTAAAGCCAACAGGGAGAAGATGACCCAGATC
ATGTTCGAAACCTTCAATGTTCCTGCCATGTATGTTGCCATTCAAGCTGTGCTCTCGCTCTATG
CATCTGGCCGCACCACAGGCATCGTCCTGGATTCAGGGGATGGCGTCACCCACAATGTCCCCAT
CTACGAGGGCTATGCACTGCCCCATGCCATCATGCGTCTTGACCTGGCTGGACGGGATCTCACA
GACTACCTCATGAAAATTCTCACAGAAAGAGGCTATTCCTTTGTGACCACAGCTGAGAGAGAAA
TTGTGCGAGACATCAAGGAGAAGCTGTGCTACGTAGCCCTGGATTTTGAGAATGAGATGGCCAC
GGCGGCTTCGTCTTCTTCCCTGGAGAAGAGCTACGAGTTGCCTGATGGGCAGGTCATCACGATT
GGCAATGAGCGCTTCCGCTGCCCGGAGACCCTGTTCCAGCCTTCCTTCATTGGCATGGAGTCAG
CTGGAATTCATGAGACAACATACAATTCCATCATGAAGTGTGACATTGACATCCGCAAGGATTT
GTATGCTAACAATGTCCTCTCTGGGGGCACTACCATGTACCCTGGGATTGCTGACAGGATGCAG
AAGGAGATCACAGCCTTGGCTCCCAGCACCATGAAGATCAAGATCATCGCTCCTCCGGAGCGGA
AGTACTCAGTCTGGATTGGAGGCTCCATCCTGGCTTCTCTCTCCACCTTCCAGCAAATGTGGAT
CAGCAAGCCAGAGTATGATGAAGCGGGGCCCTCCATTGTCCACAGGAAATGCTTCTAAAGTCAC
AGGGCCTTCTCTGGGGATCCCTGCAAGACTGCTGTCACCAGTCACAGATCATTAAAACCTTCAA
GCCTTAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006236728 ⟹ XP_006236790

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	117,579,513 - 117,604,379 (-)	NCBI
mRatBN7.2	4	116,021,832 - 116,046,475 (-)	NCBI
Rnor_6.0	4	115,215,160 - 115,239,746 (-)	NCBI
Rnor_5.0	4	179,805,782 - 179,830,362 (-)	NCBI

Sequence:

show sequence

TTTAAAGAAGATCCGCCTTGGGGGTTTTATATTGCTCTGGTATTTCTGCCAAAGACACCACGGC
CCTCAGTCTCTCGGAGAAGGACTTCTCACACCCTTGGTGCTCCAGCCCCCAGCTCTCTCCACCG
CGCCCACCATGTGTGAAGAAGAGACCACCGCCCTTGTGTGTGACAATGGGTCTGGCCTGTGCAA
GGCAGGCTTTGCAGGAGACGACGCTCCCAGGGCTGTCTTTCCCTCCATTGTGGGCCGCCCTCGG
CATCAGGGCGTGATGGTGGGAATGGGCCAGAAAGACAGCTATGTGGGGGACGAAGCCCAGAGCA
AGCGTGGGATCCTGACCCTCAAATACCCCATTGAACACGGCATCATCACGAACTGGGATGACAT
GGAGAAGATCTGGCACCACTCCTTCTACAACGAGCTGCGAGTAGCACCAGAAGAGCACCCGACC
CTGCTCACAGAGGCCCCCCTAAACCCTAAAGCCAACAGGGAGAAGATGACCCAGATCATGTTCG
AAACCTTCAATGTTCCTGCCATGTATGTTGCCATTCAAGCTGTGCTCTCGCTCTATGCATCTGG
CCGCACCACAGGCATCGTCCTGGATTCAGGGGATGGCGTCACCCACAATGTCCCCATCTACGAG
GGCTATGCACTGCCCCATGCCATCATGCGTCTTGACCTGGCTGGACGGGATCTCACAGACTACC
TCATGAAGATTCTCACAGAAAGAGGCTATTCCTTTGTGACCACAGCTGAGAGAGAAATTGTGCG
AGACATCAAGGAGAAGCTGTGCTACGTAGCCCTGGATTTTGAGAATGAGATGGCCACGGCGGCT
TCGTCTTCTTCCCTGGAGAAGAGCTACGAGTTGCCTGATGGGCAGGTCATCACGATTGGCAATG
AGCGCTTCCGCTGCCCGGAGACCCTGTTCCAGCCTTCCTTCATTGGCATGGAGTCAGCTGGAAT
TCATGAGACAACATACAATTCCATCATGAAGTGTGACATTGACATCCGCAAGGATTTGTATGCT
AACAATGTCCTCTCTGGGGGCACTACCATGTACCCTGGGATTGCTGACAGGATGCAGAAGGAGA
TCACAGCCTTGGCTCCCAGCACCATGAAGATCAAGATCATCGCTCCTCCGGAGCGGAAGTACTC
AGTCTGGATTGGAGGCTCCATCCTGGCTTCTCTCTCCACCTTCCAGCAAATGTGGATCAGCAAG
CCAGAGTATGATGAAGCGGGGCCCTCCATTGTCCACAGGAAATGCTTCTAAAGTCACAGGGCCT
TCTCTGGGGATCCCTGCAAGACTGCTGTCACCAGTCACAGATCATTAAAACCTTCAAGCCTTA

hide sequence

Protein Sequences


Protein RefSeqs	NP_037025	(Get FASTA)	NCBI Sequence Viewer
	XP_006236790	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA40672	(Get FASTA)	NCBI Sequence Viewer
	AAH87689	(Get FASTA)	NCBI Sequence Viewer
	EDL91149	(Get FASTA)	NCBI Sequence Viewer
	EDL91150	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000050322
	ENSRNOP00000050322.2
	ENSRNOP00000073101
GenBank Protein	P63269	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_037025 ⟸ NM_012893

- UniProtKB:

P63269 (UniProtKB/Swiss-Prot), A6IAN1 (UniProtKB/TrEMBL), A0A0G2K4M6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRG
ILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETF
NVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMK
ILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERF
RCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITA
LAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF

hide sequence

RefSeq Acc Id:	XP_006236790 ⟸ XM_006236728
- Peptide Label:	isoform X1
- UniProtKB:	P63269 (UniProtKB/Swiss-Prot), A6IAN1 (UniProtKB/TrEMBL), A0A0G2K4M6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MCEEETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRG ILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPTLLTEAPLNPKANREKMTQIMFETF NVPAMYVAIQAVLSLYASGRTTGIVLDSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMK ILTERGYSFVTTAEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNERF RCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGTTMYPGIADRMQKEITA LAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWISKPEYDEAGPSIVHRKCF hide sequence

Ensembl Acc Id:

ENSRNOP00000050322 ⟸ ENSRNOT00000042699

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P63269-F1-model_v2	AlphaFold	P63269	1-376	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693181

Promoter ID:

EPDNEW_R3705

Type:

multiple initiation site

Name:

Actg2_1

Description:

actin, gamma 2, smooth muscle, enteric

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	115,239,689 - 115,239,749	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2027	AgrOrtholog
BioCyc Gene	G2FUF-44003	BioCyc
Ensembl Genes	ENSRNOG00000029401	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00000058039	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000042699	ENTREZGENE
	ENSRNOT00000042699.5	UniProtKB/Swiss-Prot
	ENSRNOT00000083468	UniProtKB/TrEMBL
Gene3D-CATH	3.30.420.40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Actin, Chain A, domain 2	UniProtKB/TrEMBL
	Actin, Chain A, domain 4	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7310913	IMAGE-MGC_LOAD
InterPro	Actin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Actin/actin-like_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Actin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ATPase_NBD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:25365	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:105507	IMAGE-MGC_LOAD
NCBI Gene	25365	ENTREZGENE
PANTHER	ACTIN	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
Pfam	Actin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Actg2	PhenoGen
PRINTS	ACTIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ACTINS_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ACTINS_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ACTINS_ACT_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000029401	RatGTEx
	ENSRNOG00000058039	RatGTEx
SMART	ACTIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Actin-like ATPase domain	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
TIGR	TC217240
UniProt	A0A0G2K4M6	ENTREZGENE, UniProtKB/TrEMBL
	A6IAN1	ENTREZGENE, UniProtKB/TrEMBL
	A6IAN2_RAT	UniProtKB/TrEMBL
	ACTH_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	P12718	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-03-25	Actg2	actin gamma 2, smooth muscle	Actg2	actin, gamma 2, smooth muscle, enteric	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-14	Actg2	actin, gamma 2, smooth muscle, enteric	Actg2	actin, gamma 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-11-06	Actg2	actin, gamma 2		Actin, gamma 2, smooth muscle, enteric	Name updated	625702	APPROVED
2002-06-10	Actg2	Actin, gamma 2, smooth muscle, enteric			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in stomach smooth muscle	631723
gene_homology	mature protein is nearly identical to that of the chicken gizzard gamma actin sequence with one differing amino acid	631723
gene_product	member of the actin family	631723

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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