Gabarapl1 (GABA type A receptor associated protein like 1)

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Gene: Gabarapl1 (GABA type A receptor associated protein like 1) Rattus norvegicus

Analyze

Symbol:

Gabarapl1

Name:

GABA type A receptor associated protein like 1

RGD ID:

1596143

Description:

Predicted to enable several functions, including GABA receptor binding activity; Tat protein binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in autophagy of mitochondrion; cellular response to nitrogen starvation; and macroautophagy. Located in cell body; dendrite cytoplasm; and dendrite membrane. Orthologous to human GABARAPL1 (GABA type A receptor associated protein like 1); PARTICIPATES IN autophagy pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

GABA(A) receptor-associated protein like 1; GABA(A) receptor-associated protein-like 1; gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1; gamma-aminobutyric acid receptor-associated protein-like 1; GEC-1; Gec1; glandular epithelial cell protein 1; MGC125167; similar to gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	162,980,309 - 162,989,452 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	162,980,249 - 162,989,450 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	169,215,126 - 169,224,269 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	164,998,073 - 165,007,216 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	163,632,124 - 163,641,266 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	163,293,724 - 163,302,866 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	163,293,724 - 163,302,858 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	211,937,475 - 211,946,617 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	166,802,106 - 166,811,249 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	151,664,636 - 151,673,783 (+)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (EXP)

4-hydroxynon-2-enal (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrylamide (EXP)

adefovir pivoxil (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

atrazine (ISO)

avobenzone (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzoates (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

bortezomib (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

chloroacetaldehyde (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clodronic acid (ISO)

cobalt dichloride (EXP,ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

crotonaldehyde (ISO)

CU-O LINKAGE (ISO)

cyclosporin A (ISO)

cytarabine (ISO)

diallyl trisulfide (ISO)

dibenzofurans (ISO)

dibutyl phthalate (EXP,ISO)

dicrotophos (ISO)

dioxygen (ISO)

doxorubicin (ISO)

enniatin (EXP)

ethanol (ISO)

folic acid (ISO)

glafenine (EXP)

hydrogen peroxide (ISO)

inulin (ISO)

isoprenaline (ISO)

leflunomide (EXP)

mercury dibromide (ISO)

methimazole (EXP)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

methylseleninic acid (ISO)

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal (ISO)

N-methylformamide (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

niclosamide (ISO)

oxaliplatin (EXP)

ozone (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

paraquat (ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

phenethyl isothiocyanate (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

rotenone (EXP,ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sirolimus (ISO)

sodium arsenite (ISO)

sulfadimethoxine (EXP)

sulforaphane (ISO)

tetrachloromethane (ISO)

theophylline (ISO)

titanium dioxide (ISO)

topotecan (EXP)

troglitazone (ISO)

trovafloxacin (ISO)

tunicamycin (ISO)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagosome assembly (IBA)

autophagy (IEA)

autophagy of mitochondrion (IBA)

biological_process (ND)

cellular response to nitrogen starvation (IBA)

glycophagy (ISO)

macroautophagy (IBA)

Cellular Component

autophagosome (IBA,ISO)

autophagosome membrane (IBA)

cell body (IDA)

cytoplasmic vesicle membrane (IEA)

cytosol (IBA)

dendrite cytoplasm (IDA)

dendrite membrane (IDA)

endoplasmic reticulum (IEA)

Golgi apparatus (IEA)

membrane (IEA)

microtubule (IEA)

mitochondrion (ISO)

Molecular Function

GABA receptor binding (IBA)

phospholipid binding (ISO)

protein binding (IPI,ISO)

Tat protein binding (ISO)

ubiquitin protein ligase binding (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

autophagy pathway (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Network organization of the human autophagy system.	Behrends C, etal., Nature. 2010 Jul 1;466(7302):68-76. Epub 2010 Jun 20.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation
7.	Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.	Seguin-Py S, etal., Biochimie. 2011 Nov 20.
8.	Distribution and ultrastructural localization of GEC1 in the rat CNS.	Wang Y, etal., Neuroscience. 2006 Jul 21;140(4):1265-76. Epub 2006 May 2.

Additional References at PubMed

PMID:12477932	PMID:15292400	PMID:18423580	PMID:19524128	PMID:20200478	PMID:22354992	PMID:25127057

Genomics

Comparative Map Data

Gabarapl1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	4	162,980,309 - 162,989,452 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	162,980,249 - 162,989,450 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	169,215,126 - 169,224,269 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	164,998,073 - 165,007,216 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	163,632,124 - 163,641,266 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	163,293,724 - 163,302,866 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	163,293,724 - 163,302,858 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	211,937,475 - 211,946,617 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	166,802,106 - 166,811,249 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	4	151,664,636 - 151,673,783 (+)	NCBI		Celera
Cytogenetic Map	4	q42	NCBI

GABARAPL1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	10,212,877 - 10,223,128 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	10,212,458 - 10,223,128 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	10,365,476 - 10,375,727 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	10,256,756 - 10,266,994 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	10,256,755 - 10,266,989	NCBI
Celera	12	15,526,610 - 15,536,854 (+)	NCBI		Celera
Cytogenetic Map	12	p13.2	NCBI
HuRef	12	10,108,873 - 10,119,144 (+)	NCBI		HuRef
CHM1_1	12	10,334,782 - 10,345,019 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	10,099,612 - 10,109,862 (+)	NCBI		T2T-CHM13v2.0

Gabarapl1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	129,510,155 - 129,519,294 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	129,510,123 - 129,519,309 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	129,533,192 - 129,542,331 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	129,533,160 - 129,542,346 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	129,483,210 - 129,492,349 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	129,498,885 - 129,508,024 (+)	NCBI		MGSCv36	mm8
Celera	6	131,256,899 - 131,266,042 (+)	NCBI		Celera
Cytogenetic Map	6	F3	NCBI
cM Map	6	63.39	NCBI

Gabarapl1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	7,653,396 - 7,661,835 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	7,653,396 - 7,661,835 (-)	NCBI	ChiLan1.0	ChiLan1.0

GABARAPL1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	12	15,690,411 - 15,700,667 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	10,251,006 - 10,261,292 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	10,501,694 - 10,511,880 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	10,501,694 - 10,511,880 (+)	Ensembl	panpan1.1		panPan2

GABARAPL1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	27	35,783,203 - 35,791,576 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	27	35,782,330 - 35,791,569 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	27	10,832,076 - 10,840,433 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	27	36,129,419 - 36,137,791 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	27	36,128,546 - 36,137,800 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	27	36,017,634 - 36,026,003 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	27	36,039,664 - 36,048,013 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	27	10,353,533 - 10,361,896 (+)	NCBI		UU_Cfam_GSD_1.0

Gabarapl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	97,232,591 - 97,241,104 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936902	362,282 - 373,459 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936902	364,158 - 372,888 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GABARAPL1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	61,758,130 - 61,767,601 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	61,758,127 - 61,767,427 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	64,622,416 - 64,631,775 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GABARAPL1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	10,087,582 - 10,099,125 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	10,087,604 - 10,096,612 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666089	2,162,836 - 2,174,383 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gabarapl1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	26,971,187 - 26,981,929 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624752	26,971,266 - 26,979,483 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gabarapl1
96 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	265
Count of miRNA genes:	180
Interacting mature miRNAs:	197
Transcripts:	ENSRNOT00000011942
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
1576316	Ept5	Estrogen-induced pituitary tumorigenesis QTL 5	3.8		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	4	83428419	177635233	Rat
1358202	Gluco11	Glucose level QTL 11	2.4	0.02	adipocyte glucose uptake trait (VT:0004185)	absolute change in adipocyte glucose uptake (CMO:0000873)	4	85379421	167139601	Rat
634335	Anxrr16	Anxiety related response QTL 16	7.22		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	93308457	167139447	Rat
737821	Hcar9	Hepatocarcinoma resistance QTL 9	3.7		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	109866907	167139601	Rat
1331759	Hrtrt13	Heart rate QTL 13	3.54628		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	110275411	168266883	Rat
724535	Cm18	Cardiac mass QTL 18	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	4	118856416	163856416	Rat
634347	Hcar8	Hepatocarcinoma resistance QTL 8	5.8		liver integrity trait (VT:0010547)	liver tumorous lesion area to total liver area ratio (CMO:0001075)	4	123143783	168143783	Rat
631683	Bp116	Blood pressure QTL 116		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	124303370	169303370	Rat
6478778	Anxrr51	Anxiety related response QTL 51		0.25384	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	124778595	169778595	Rat
7411558	Bw133	Body weight QTL 133	13.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	125590636	170590636	Rat
61451	Ciaa4	CIA Autoantibody QTL 4	3.1		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	4	126395976	167139601	Rat
737978	Pia23	Pristane induced arthritis QTL 23	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	131730738	167139601	Rat
631511	Pia7	Pristane induced arthritis QTL 7	4.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	131730738	167139601	Rat
1549827	Scl46	Serum cholesterol level QTL 46	3.5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	4	132396220	177396220	Rat
724558	Plsm2	Polydactyly-luxate syndrome (PLS) morphotypes QTL 2		0.0003	hindlimb integrity trait (VT:0010563)	hind foot phalanges count (CMO:0001949)	4	132422778	177422778	Rat
61422	Cia13	Collagen induced arthritis QTL 13	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	132642577	167139601	Rat
2303623	Vencon2	Ventilatory control QTL 2	3.8		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	4	135204660	180204660	Rat
1578674	Bmd12	Bone mineral density QTL 12	3.8		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	4	135699135	180699135	Rat
2293659	Bmd35	Bone mineral density QTL 35	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	4	137755016	181392681	Rat
61362	Oia2	Oil induced arthritis QTL 2		0.001	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	138503169	173369699	Rat
1298524	Oia8	Oil induced arthritis QTL 8			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	138503169	173369699	Rat
1331738	Bp209	Blood pressure QTL 209	2.979		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	138503169	179293946	Rat
6478718	Anxrr34	Anxiety related response QTL 34		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
6478748	Anxrr42	Anxiety related response QTL 42		0.28008	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
6478754	Anxrr43	Anxiety related response QTL 43		0.14035	locomotor behavior trait (VT:0001392)	distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)	4	144639524	182687754	Rat
6478693	Anxrr32	Anxiety related response QTL 32		0.00092	locomotor behavior trait (VT:0001392)	measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)	4	144639524	182687754	Rat
6478700	Anxrr33	Anxiety related response QTL 33		0.00896	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	144639524	182687754	Rat
10401796	Kidm48	Kidney mass QTL 48			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	145568712	182687754	Rat
634342	Cia24	Collagen induced arthritis QTL 24	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	146565735	175236377	Rat
12798525	Anxrr57	Anxiety related response QTL 57	3.21	0.05	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	147278504	167139601	Rat
1582237	Kidm34	Kidney mass QTL 34	4	0.0001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	4	148090542	168069246	Rat
10053718	Scort25	Serum corticosterone level QTL 25	2.15	0.0097	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	155561574	182687754	Rat
1300109	Rf13	Renal function QTL 13	3.91		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	4	157710145	182687754	Rat

Markers in Region

RH141590

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	162,979,557 - 162,979,762 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	163,292,973 - 163,293,177	NCBI	Rnor6.0
Rnor_5.0	4	211,936,724 - 211,936,928	UniSTS	Rnor5.0
RGSC_v3.4	4	166,801,355 - 166,801,559	UniSTS	RGSC3.4
Celera	4	151,663,885 - 151,664,089	UniSTS
RH 3.4 Map	4	1013.4	UniSTS
Cytogenetic Map	4	q42	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001044294	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC115156	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC105627	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473964	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000077356 ⟹ ENSRNOP00000075223

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	162,980,249 - 162,989,450 (+)	Ensembl
Rnor_6.0 Ensembl	4	163,293,724 - 163,302,858 (+)	Ensembl

RefSeq Acc Id:

NM_001044294 ⟹ NP_001037759

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	4	162,980,309 - 162,989,452 (+)	NCBI
Rnor_6.0	4	163,293,724 - 163,302,866 (+)	NCBI
Rnor_5.0	4	211,937,475 - 211,946,617 (+)	NCBI
RGSC_v3.4	4	166,802,106 - 166,811,249 (+)	RGD
Celera	4	151,664,636 - 151,673,783 (+)	RGD

Sequence:

show sequence

CCAGGTCCCTCTCTGGACGTTTGGTCACGTAGTGCGGCGACCAGAGCGTGGGAGCTGACGCGGG
TGGAGCGATTGTGATAAGGCTGACATTGACTGGGGGTGGCCAGACGGGAGACGCGGTCAACAGC
GCGCGCAGCAGGCCCCGTCCGGGGAGCCCCTACATCCTGCGATCCATCATGAAGTTCCAGTATA
AAGAGGACCACCCCTTCGAATATCGGAAAAAGGAAGGTGAAAAAATAAGGAAGAAATACCCGGA
CAGGGTGCCGGTCATCGTGGAGAAGGCTCCTAAAGCCAGGGTCCCCGATCTGGATAAGAGGAAG
TACCTTGTGCCCTCCGACCTCACTGTTGGCCAGTTCTACTTCTTAATCCGGAAGAGGATCCACC
TGAGACCTGAGGACGCCTTATTCTTCTTTGTCAACAACACTATCCCTCCCACCAGTGCTACCAT
GGGACAGCTGTATGAGGACAACCATGAGGAAGACTATTTTCTGTATGTGGCCTACAGTGATGAA
AGTGTCTACGGGAAATGAGGCAGAAGCCCAGCAGATGGGAGCGCCTGGACTTGGGGGTAGGGGA
GGGGTGCGTGTGGGACTTGGGGAACCAGAGGGAGGGCTCCCAACCATGGAGGAGACGCAAGGTG
AAGACATCAGGAAACATCACACCGCACACGCTGTCGTCTTTTATTCACGAGCTCAATTGTTACT
TTTTCTCTGCTTCCCCAGCCCAGGAAGAACTTGTGTTGGATTGGCTGTGAGAGCGGGATGGGGA
CAACACGATCCACAGCCTTGCTGTGTGTGAGCTTTCTTTCGTGTAGTTTCATCAGAGGTTTGGG
AGGGGGCAGGTGACCGATAGAGAAGAAGACAGTTCAGCAGCAACTCTCGTCACTTTGGGCAGAG
GTTTGACTTTGTGGCATTTGTACAAGCCACCAGGCAAAGGGGGAAAGAATGCTGTAGGGGACCA
TACCTAAGGGACCAAAAGATACCCACTGTTACTGAAGCATTTCGACCTTTGACCTCTGCCCTAA
TTCCTTCCTCTCCTAGTCCTTTTCCTCCGCCCAGGTGTCATAGCACCGCCCCAGTTGTGGCAGT
AGACATTCGCACGGACATTTAGATGGAGTCCTCTTGGAAAATAGGGCTGTTCGCAATGTGGTTG
TGATTGCCAGCAGTTTGGATGGCGTTAAAGTGGAGTTCAGGGTTGAACATGTCCCGCTCTTCTT
CCCACAAGAACCTTGGACTTTCAGGAGCCTCAGGATCAGTCCTCTAGCATTTCCTTCACCTTTC
TCATGGACAGGGACAGCGTGTCTGTGTGTGGAGGGTCGGGGTTACAAGGTAAGCTAGGTCACAC
ACCTGCCGCTCGTCCTCCCCCTGCTGCAGTCTCTTAGGTCTCACTCGCACTGGAATGCAAAGCG
ATGGCCAGCTGTCTCCCTCCGCGGCATCTGCTATCGAGAGAAGATGGAACGAGGGGCGCCAGAG
TTTCATGGGGGCTTTACTCATTCATTTCATTTAGGGACTCTGTTGGGGGGAGGGGCAGGAATCG
CATTCACACATGACATTTCAATTCATCTCTACAAATGAAGAGCGTCCTCCCCGTTGGGAGCTAT
CTGTATGTTCGCTTTGTCGGCATCAGGTTCTGGGACTTTGAAGTCAATTGCTGTCAGGCCAGGG
AAATAAAATAATTGCTTACCTTAAAAAATCAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001037759	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI05628	(Get FASTA)	NCBI Sequence Viewer
	EDM01729	(Get FASTA)	NCBI Sequence Viewer
	EDM01731	(Get FASTA)	NCBI Sequence Viewer
	Q0VGK0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001037759 ⟸ NM_001044294
- UniProtKB:	Q0VGK0 (UniProtKB/Swiss-Prot), A6IM58 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQFYFLI RKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK hide sequence

RefSeq Acc Id:

ENSRNOP00000075223 ⟸ ENSRNOT00000077356

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q0VGK0-F1-model_v2	AlphaFold	Q0VGK0	1-117	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1596143	AgrOrtholog
BioCyc Gene	G2FUF-42773	BioCyc
Ensembl Genes	ENSRNOG00000053362	Ensembl, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000075223.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000077356.2	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7323087	IMAGE-MGC_LOAD
InterPro	Atg8-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ubiquitin-like_domsf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:689161	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:125167	IMAGE-MGC_LOAD
NCBI Gene	689161	ENTREZGENE
PANTHER	GABA TYPE A RECEPTOR ASSOCIATED PROTEIN LIKE 1	UniProtKB/TrEMBL
	GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10969	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Atg8	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gabarapl1	PhenoGen
Superfamily-SCOP	SSF54236	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8L2RBX1_RAT	UniProtKB/TrEMBL
	A6IM58	ENTREZGENE, UniProtKB/TrEMBL
	GBRL1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-29	Gabarapl1	GABA type A receptor associated protein like 1	Gabarapl1	GABA(A) receptor-associated protein like 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-19	Gabarapl1	GABA(A) receptor-associated protein like 1	Gabarapl1	gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Gabarapl1	gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1	MGC125167	similar to gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	MGC125167	similar to gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1	LOC683917	similar to gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1	Data Merged	1643240	APPROVED
2006-11-20	MGC125167	similar to gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-11-20	LOC683917	similar to gamma-aminobutyric acid (GABA(A)) receptor-associated protein-like 1			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Imported Annotations - KEGG (archival)