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Gene: Nexn (nexilin (F actin binding protein)) Rattus norvegicus
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Symbol: Nexn
Name: nexilin (F actin binding protein)
Description: Exhibits actin filament binding activity. Predicted to be involved in several processes, including homophilic cell adhesion via plasma membrane adhesion molecules; neuron development; and response to bacterium. Localizes to the Z disc and cell-substrate adherens junction. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Orthologous to human NEXN (nexilin F-actin binding protein); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC246172; nexilin
Orthologs:
Homo sapiens (human) : NEXN (nexilin F-actin binding protein)  HGNC  Alliance
Mus musculus (house mouse) : Nexn (nexilin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nexn (nexilin F-actin binding protein)
Pan paniscus (bonobo/pygmy chimpanzee) : NEXN (nexilin F-actin binding protein)
Canis lupus familiaris (dog) : NEXN (nexilin F-actin binding protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nexn (nexilin F-actin binding protein)
Sus scrofa (pig) : NEXN (nexilin F-actin binding protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02257,452,937 - 257,484,607 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02276,129,684 - 276,161,434 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42250,762,017 - 250,783,765 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12250,776,623 - 250,798,372 (-)NCBI
Celera2233,122,059 - 233,142,757 (-)NCBICelera
Cytogenetic Map2q45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nexn
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 708354
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.