Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TSPAN33 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Tspan33 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TSPAN33 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | increases expression | ISO | Tspan33 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of TSPAN33 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | Tspan33 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of TSPAN33 mRNA | CTD | PMID:17555576 | 17beta-estradiol | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of TSPAN33 mRNA | CTD | PMID:30165855 | 2,3',4,4',5-Pentachlorobiphenyl | affects expression | ISO | Tspan33 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tspan33 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TSPAN33 mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tspan33 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TSPAN33 mRNA | CTD | PMID:28922406 and PMID:33956508 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tspan33 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TSPAN33 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TSPAN33 mRNA | CTD | PMID:18796159 more ... | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of TSPAN33 mRNA | CTD | PMID:28522335 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TSPAN33 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | increases expression | ISO | Tspan33 (Mus musculus) | 6480464 | bisphenol S results in increased expression of TSPAN33 mRNA | CTD | PMID:33297965 | 4-hydroxyphenyl retinamide | increases expression | ISO | Tspan33 (Mus musculus) | 6480464 | Fenretinide results in increased expression of TSPAN33 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TSPAN33 mRNA | CTD | PMID:36843608 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of TSPAN33 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of TSPAN33 mRNA | CTD | PMID:32763439 | aflatoxin B1 | affects expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of TSPAN33 protein | CTD | PMID:20106945 | aflatoxin B1 | increases methylation | ISO | TSPAN33 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of TSPAN33 intron | CTD | PMID:30157460 | aflatoxin B1 | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of TSPAN33 mRNA | CTD | PMID:21641981 | aflatoxin B1 | increases expression | ISO | Tspan33 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of TSPAN33 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of TSPAN33 mRNA | CTD | PMID:23724009 and PMID:33167477 | antirheumatic drug | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of TSPAN33 mRNA | CTD | PMID:24449571 | benzene | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Benzene results in decreased expression of TSPAN33 mRNA | CTD | PMID:19162166 | benzo[a]pyrene | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TSPAN33 mRNA | CTD | PMID:20106945 and PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | TSPAN33 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TSPAN33 3' UTR and Benzo(a)pyrene affects the methylation of TSPAN33 intron | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | TSPAN33 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TSPAN33 promoter | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | ISO | Tspan33 (Mus musculus) | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of TSPAN33 mRNA] | CTD | PMID:22228805 | benzo[a]pyrene | decreases expression | ISO | Tspan33 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of TSPAN33 mRNA | CTD | PMID:22228805 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TSPAN33 promoter | CTD | PMID:23359474 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Tspan33 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TSPAN33 mRNA | CTD | PMID:28085963 | bisphenol A | decreases expression | ISO | Tspan33 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TSPAN33 mRNA | CTD | PMID:21932408 | bisphenol A | increases expression | ISO | Tspan33 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TSPAN33 mRNA | CTD | PMID:32156529 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TSPAN33 mRNA | CTD | PMID:32145629 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TSPAN33 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TSPAN33 promoter | CTD | PMID:23359474 | bisphenol F | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TSPAN33 mRNA | CTD | PMID:28628672 | butanal | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of TSPAN33 mRNA | CTD | PMID:26079696 | cadmium atom | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Cadmium results in increased expression of TSPAN33 mRNA | CTD | PMID:24376830 | carbamazepine | affects expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of TSPAN33 mRNA | CTD | PMID:25979313 | chlorpyrifos | increases expression | ISO | Tspan33 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of TSPAN33 mRNA | CTD | PMID:37019170 | cisplatin | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of TSPAN33 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TSPAN33 mRNA | CTD | PMID:27392435 and PMID:27594783 | cyclosporin A | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TSPAN33 mRNA | CTD | PMID:20106945 | dexamethasone | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TSPAN33 mRNA | CTD | PMID:28628672 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate] affects the methylation of TSPAN33 promoter | CTD | PMID:23359474 | dichloroacetic acid | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Dichloroacetic Acid results in decreased expression of TSPAN33 mRNA | CTD | PMID:33405312 | dorsomorphin | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | ethyl methanesulfonate | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of TSPAN33 mRNA | CTD | PMID:23649840 | formaldehyde | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of TSPAN33 mRNA | CTD | PMID:23649840 | genistein | decreases expression | ISO | Tspan33 (Mus musculus) | 6480464 | Genistein results in decreased expression of TSPAN33 mRNA | CTD | PMID:32186404 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of TSPAN33 mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of TSPAN33 mRNA | CTD | PMID:28628672 | ketamine | increases expression | EXP | | 6480464 | Ketamine results in increased expression of TSPAN33 mRNA | CTD | PMID:20080153 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of TSPAN33 mRNA | CTD | PMID:24136188 | methyl methanesulfonate | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TSPAN33 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of TSPAN33 mRNA | CTD | PMID:28001369 | nickel sulfate | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of TSPAN33 mRNA | CTD | PMID:22714537 | oxaliplatin | decreases expression | EXP | | 6480464 | oxaliplatin results in decreased expression of TSPAN33 mRNA | CTD | PMID:25729387 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of TSPAN33 mRNA | CTD | PMID:25729387 | paracetamol | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TSPAN33 mRNA | CTD | PMID:22230336 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TSPAN33 mRNA | CTD | PMID:33387578 | pentanal | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | pentanal results in increased expression of TSPAN33 mRNA | CTD | PMID:26079696 | perfluorohexanesulfonic acid | decreases expression | ISO | Tspan33 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of TSPAN33 mRNA | CTD | PMID:37995155 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tspan33 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TSPAN33 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of TSPAN33 mRNA | CTD | PMID:36331819 | phenylmercury acetate | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TSPAN33 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | ISO | Tspan33 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TSPAN33 mRNA | CTD | PMID:18301758 | propanal | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of TSPAN33 mRNA | CTD | PMID:26079696 | propiconazole | decreases expression | ISO | Tspan33 (Mus musculus) | 6480464 | propiconazole results in decreased expression of TSPAN33 mRNA | CTD | PMID:21278054 | SB 431542 | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sunitinib | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of TSPAN33 mRNA | CTD | PMID:31533062 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TSPAN33 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of TSPAN33 mRNA] | CTD | PMID:31150632 | thalidomide | decreases expression | ISO | Tspan33 (Mus musculus) | 6480464 | Thalidomide results in decreased expression of TSPAN33 mRNA | CTD | PMID:26217789 | thimerosal | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of TSPAN33 mRNA | CTD | PMID:27188386 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TSPAN33 mRNA | CTD | PMID:34492290 | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of TSPAN33 mRNA | CTD | PMID:25729387 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of TSPAN33 mRNA | CTD | PMID:25729387 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of TSPAN33 mRNA | CTD | PMID:33387578 | trichostatin A | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of TSPAN33 mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | TSPAN33 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of TSPAN33 mRNA | CTD | PMID:27188386 | triclosan | decreases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Triclosan results in decreased expression of TSPAN33 mRNA | CTD | PMID:30510588 | tunicamycin | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Tunicamycin results in increased expression of TSPAN33 mRNA | CTD | PMID:22378314 | valproic acid | affects expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TSPAN33 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | TSPAN33 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TSPAN33 mRNA | CTD | PMID:19101580 more ... | |