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Gene: Fkbp1a (FKBP prolyl isomerase 1A) Rattus norvegicus
Symbol: Fkbp1a
Name: FKBP prolyl isomerase 1A
RGD ID: 2617
Description: Exhibits several functions, including FK506 binding activity; Hsp70 protein binding activity; and type I transforming growth factor beta receptor binding activity. Involved in response to iron ion. Localizes to axon terminus and intracellular membrane-bounded organelle. Orthologous to several human genes including FKBP1A (FKBP prolyl isomerase 1A); PARTICIPATES IN activin signaling pathway; mTOR signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
Also known as: 12 kDa FK506-binding protein; 12 kDa FKBP; FK506 binding protein 1a; FK506 binding protein 2; FK506 binding protein 2 (13 kDa); FK506-binding protein 1 (12kD); FK506-binding protein 1a; FKBP-12; FKBP-1A; FKBP12; Fkbp2; immunophilin FKBP12; MGC156543; peptidyl-prolyl cis-trans isomerase FKBP1A; PPIase FKBP1A; rotamase
Homo sapiens (human) : FKBP1A (FKBP prolyl isomerase 1A)  HGNC  Alliance
Mus musculus (house mouse) : Fkbp1a (FK506 binding protein 1a)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fkbp1a (FKBP prolyl isomerase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : FKBP1A (FKBP prolyl isomerase 1A)
Canis lupus familiaris (dog) : FKBP1A (FKBP prolyl isomerase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fkbp1a (FKBP prolyl isomerase 1A)
Sus scrofa (pig) : FKBP1A (FKBP prolyl isomerase 1A)
Chlorocebus sabaeus (African green monkey) : FKBP1A (FKBP prolyl isomerase 1A)
Heterocephalus glaber (naked mole-rat) : Fkbp1a (FKBP prolyl isomerase 1A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03147,042,944 - 147,062,725 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,042,944 - 147,062,724 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03153,399,455 - 153,418,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,861,237 - 141,880,797 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13141,766,809 - 141,786,369 (+)NCBI
Celera3138,799,643 - 138,819,482 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Fkbp1a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2617
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.