Fkbp1a (FKBP prolyl isomerase 1A) - Rat Genome Database

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Gene: Fkbp1a (FKBP prolyl isomerase 1A) Chinchilla lanigera
Analyze
Symbol: Fkbp1a
Name: FKBP prolyl isomerase 1A
RGD ID: 8920470
Description: ENCODES a protein that exhibits activin receptor binding (ortholog); channel regulator activity (ortholog); enzyme binding (ortholog); INVOLVED IN amyloid fibril formation (ortholog); cytokine-mediated signaling pathway (ortholog); heart morphogenesis (ortholog); PARTICIPATES IN activin signaling pathway; mTOR signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Barth syndrome (ortholog); congenital heart disease (ortholog); esophagus squamous cell carcinoma (ortholog); FOUND IN axon terminus (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FK506 binding protein 1A; FK506 binding protein 1A, 12kDa; peptidyl-prolyl cis-trans isomerase FKBP1A
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955596580,106 - 603,255 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955596580,106 - 606,210 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Fkbp1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955596580,106 - 603,255 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955596580,106 - 606,210 (-)NCBIChiLan1.0ChiLan1.0
FKBP1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38201,368,978 - 1,393,054 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl201,368,977 - 1,393,164 (-)EnsemblGRCh38hg38GRCh38
GRCh37201,349,622 - 1,373,698 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36201,297,622 - 1,321,745 (-)NCBINCBI36Build 36hg18NCBI36
Build 34201,300,375 - 1,321,745NCBI
Celera201,445,967 - 1,470,163 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef201,302,109 - 1,326,302 (-)NCBIHuRef
CHM1_1201,349,285 - 1,373,817 (-)NCBICHM1_1
T2T-CHM13v2.0201,418,161 - 1,442,241 (-)NCBIT2T-CHM13v2.0
Fkbp1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392151,384,403 - 151,403,611 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2151,384,403 - 151,403,612 (+)EnsemblGRCm39 Ensembl
GRCm382151,542,483 - 151,561,691 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2151,542,483 - 151,561,692 (+)EnsemblGRCm38mm10GRCm38
MGSCv372151,368,235 - 151,387,427 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362151,234,062 - 151,253,132 (+)NCBIMGSCv36mm8
Celera2157,359,901 - 157,379,075 (+)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.83NCBI
Fkbp1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83160,500,748 - 160,520,492 (+)NCBIGRCr8
mRatBN7.23140,040,359 - 140,060,107 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3140,040,278 - 140,060,743 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3143,944,928 - 143,964,668 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03152,528,701 - 152,548,443 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03150,269,170 - 150,288,910 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03147,042,944 - 147,062,725 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,042,944 - 147,062,724 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03153,399,455 - 153,418,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,861,237 - 141,880,797 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13141,766,809 - 141,786,369 (+)NCBI
Celera3138,799,643 - 138,819,482 (+)NCBICelera
Cytogenetic Map3q41NCBI
FKBP1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2212,399,937 - 2,432,330 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1202,396,766 - 2,426,602 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0201,519,330 - 1,548,473 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1201,292,519 - 1,298,888 (-)NCBIpanpan1.1PanPan1.1panPan2
FKBP1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12419,618,581 - 19,643,685 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2419,618,558 - 19,643,046 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02420,310,591 - 20,335,863 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2420,310,075 - 20,335,863 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12419,587,096 - 19,612,324 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02419,692,087 - 19,717,321 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02420,122,927 - 20,148,189 (+)NCBIUU_Cfam_GSD_1.0
Fkbp1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640168,873,992 - 168,880,432 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648517,305,376 - 17,311,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FKBP1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11733,910,047 - 33,935,212 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21738,470,202 - 38,495,226 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FKBP1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1255,170,816 - 55,195,380 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660871,575,983 - 1,600,558 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fkbp1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247412,666,636 - 2,692,938 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247412,669,909 - 2,692,959 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSCLAT00000000554   ⟹   ENSCLAP00000000525
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955596580,106 - 603,255 (-)Ensembl
RefSeq Acc Id: XM_005414705   ⟹   XP_005414762
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955596580,106 - 603,038 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005414706   ⟹   XP_005414763
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955596580,106 - 603,072 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013510019   ⟹   XP_013365473
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955596583,419 - 606,210 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013510020   ⟹   XP_013365474
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955596581,275 - 603,038 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005414762 (Get FASTA)   NCBI Sequence Viewer  
  XP_005414763 (Get FASTA)   NCBI Sequence Viewer  
  XP_013365473 (Get FASTA)   NCBI Sequence Viewer  
  XP_013365474 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000000525
  ENSCLAP00000000525.1
RefSeq Acc Id: XP_005414763   ⟸   XM_005414706
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YI73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005414762   ⟸   XM_005414705
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YI73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013365474   ⟸   XM_013510020
- Peptide Label: isoform X2
- UniProtKB: A0A8C2YI73 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013365473   ⟸   XM_013510019
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSCLAP00000000525   ⟸   ENSCLAT00000000554
Protein Domains
PPIase FKBP-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000000427 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000000554 ENTREZGENE
  ENSCLAT00000000554.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.50.40 UniProtKB/TrEMBL
InterPro FKBP-type_PPIase UniProtKB/TrEMBL
  PPIase_dom_sf UniProtKB/TrEMBL
  PPIase_FKBP_dom UniProtKB/TrEMBL
NCBI Gene Fkbp1a ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/TrEMBL
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED UniProtKB/TrEMBL
Pfam FKBP_C UniProtKB/TrEMBL
PROSITE FKBP_PPIASE UniProtKB/TrEMBL
Superfamily-SCOP FKBP-like UniProtKB/TrEMBL
UniProt A0A8C2YI73 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-06 Fkbp1a  FKBP prolyl isomerase 1A    FK506 binding protein 1A  Symbol and/or name change 5135510 APPROVED
2016-08-16 Fkbp1a  FK506 binding protein 1A    FK506 binding protein 1A, 12kDa  Symbol and/or name change 5135510 APPROVED