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Gene: FKBP1A (FKBP prolyl isomerase 1A) Homo sapiens
Symbol: FKBP1A
Name: FKBP prolyl isomerase 1A
Description: Exhibits several functions, including FK506 binding activity; activin binding activity; and peptidyl-prolyl cis-trans isomerase activity. Involved in several processes, including SMAD protein complex assembly; regulation of protein metabolic process; and regulation of signal transduction. Localizes to Z disc; cytosol; and membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 12 kDa FK506-binding protein; 12 kDa FKBP; calstabin 1; calstabin-1; FK506 binding protein 1A; FK506 binding protein 1A, 12kDa; FK506 binding protein12; FK506-binding protein 1; FK506-binding protein 12; fk506-binding protein 1a; FK506-binding protein 1A (12kD); FK506-binding protein, T-cell, 12-kD; FKBP-12; FKBP-1A; FKBP1; FKBP12; FKBP12-Exip3; FKBP12C; immunophilin FKBP12; peptidyl-prolyl cis-trans isomerase FKBP1A; PKC12; PKCI2; PPIASE; PPIase FKBP1A; protein kinase C inhibitor 2; rotamase
Mus musculus (house mouse) : Fkbp1a (FK506 binding protein 1a)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fkbp1a (FKBP prolyl isomerase 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fkbp1a (FKBP prolyl isomerase 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : FKBP1A (FKBP prolyl isomerase 1A)
Canis lupus familiaris (dog) : FKBP1A (FKBP prolyl isomerase 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fkbp1a (FKBP prolyl isomerase 1A)
Sus scrofa (pig) : FKBP1A (FKBP prolyl isomerase 1A)
Chlorocebus sabaeus (African green monkey) : FKBP1A (FKBP prolyl isomerase 1A)
Heterocephalus glaber (naked mole-rat) : Fkbp1a (FKBP prolyl isomerase 1A)
more info ...
Related Pseudogenes: FKBP1AP1   FKBP1AP2   FKBP1AP3   FKBP1AP4   FKBP1C  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl201,368,978 - 1,393,172 (-)EnsemblGRCh38hg38GRCh38
GRCh38201,368,977 - 1,393,172 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37201,349,621 - 1,373,816 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36201,297,622 - 1,321,745 (-)NCBINCBI36hg18NCBI36
Build 34201,300,375 - 1,321,745NCBI
Celera201,445,967 - 1,470,163 (-)NCBI
Cytogenetic Map20p13NCBI
HuRef201,302,109 - 1,326,302 (-)NCBIHuRef
CHM1_1201,349,285 - 1,373,817 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FKBP1A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737539
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.