FKBP1A (FKBP prolyl isomerase 1A) - Rat Genome Database

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Gene: FKBP1A (FKBP prolyl isomerase 1A) Pan paniscus
Analyze
Symbol: FKBP1A
Name: FKBP prolyl isomerase 1A
RGD ID: 11954033
Description: ENCODES a protein that exhibits activin receptor binding (ortholog); channel regulator activity (ortholog); enzyme binding (ortholog); INVOLVED IN amyloid fibril formation (ortholog); cytokine-mediated signaling pathway (ortholog); heart morphogenesis (ortholog); PARTICIPATES IN activin signaling pathway; mTOR signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH Barth syndrome (ortholog); congenital heart disease (ortholog); esophagus squamous cell carcinoma (ortholog); FOUND IN axon terminus (ortholog); cytosol (ortholog); membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: FK506 binding protein 1A; peptidyl-prolyl cis-trans isomerase FKBP1A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2212,399,937 - 2,432,330 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1202,396,766 - 2,426,602 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0201,519,330 - 1,548,473 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1201,292,519 - 1,298,888 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FKBP1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2212,399,937 - 2,432,330 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1202,396,766 - 2,426,602 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0201,519,330 - 1,548,473 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1201,292,519 - 1,298,888 (-)NCBIpanpan1.1PanPan1.1panPan2
FKBP1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38201,368,978 - 1,393,054 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl201,368,977 - 1,393,164 (-)EnsemblGRCh38hg38GRCh38
GRCh37201,349,622 - 1,373,698 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36201,297,622 - 1,321,745 (-)NCBINCBI36Build 36hg18NCBI36
Build 34201,300,375 - 1,321,745NCBI
Celera201,445,967 - 1,470,163 (-)NCBICelera
Cytogenetic Map20p13NCBI
HuRef201,302,109 - 1,326,302 (-)NCBIHuRef
CHM1_1201,349,285 - 1,373,817 (-)NCBICHM1_1
T2T-CHM13v2.0201,418,161 - 1,442,241 (-)NCBIT2T-CHM13v2.0
Fkbp1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392151,384,403 - 151,403,611 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2151,384,403 - 151,403,612 (+)EnsemblGRCm39 Ensembl
GRCm382151,542,483 - 151,561,691 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2151,542,483 - 151,561,692 (+)EnsemblGRCm38mm10GRCm38
MGSCv372151,368,235 - 151,387,427 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362151,234,062 - 151,253,132 (+)NCBIMGSCv36mm8
Celera2157,359,901 - 157,379,075 (+)NCBICelera
Cytogenetic Map2G3NCBI
cM Map274.83NCBI
Fkbp1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83160,500,748 - 160,520,492 (+)NCBIGRCr8
mRatBN7.23140,040,359 - 140,060,107 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3140,040,278 - 140,060,743 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3143,944,928 - 143,964,668 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03152,528,701 - 152,548,443 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03150,269,170 - 150,288,910 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03147,042,944 - 147,062,725 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3147,042,944 - 147,062,724 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03153,399,455 - 153,418,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43141,861,237 - 141,880,797 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13141,766,809 - 141,786,369 (+)NCBI
Celera3138,799,643 - 138,819,482 (+)NCBICelera
Cytogenetic Map3q41NCBI
Fkbp1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955596580,106 - 603,255 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955596580,106 - 606,210 (-)NCBIChiLan1.0ChiLan1.0
FKBP1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12419,618,581 - 19,643,685 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2419,618,558 - 19,643,046 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.02420,310,591 - 20,335,863 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2420,310,075 - 20,335,863 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12419,587,096 - 19,612,324 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02419,692,087 - 19,717,321 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02420,122,927 - 20,148,189 (+)NCBIUU_Cfam_GSD_1.0
Fkbp1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640168,873,992 - 168,880,432 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493648517,305,376 - 17,311,797 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FKBP1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11733,910,047 - 33,935,212 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21738,470,202 - 38,495,226 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FKBP1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1255,170,816 - 55,195,380 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660871,575,983 - 1,600,558 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fkbp1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247412,666,636 - 2,692,938 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247412,669,909 - 2,692,959 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_034946897   ⟹   XP_034802788
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2212,399,937 - 2,429,074 (-)NCBI
NHGRI_mPanPan1202,396,766 - 2,425,904 (-)NCBI
Mhudiblu_PPA_v0201,519,330 - 1,548,434 (-)NCBI
RefSeq Acc Id: XM_034946899   ⟹   XP_034802790
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2212,404,858 - 2,429,060 (-)NCBI
NHGRI_mPanPan1202,401,687 - 2,425,888 (-)NCBI
Mhudiblu_PPA_v0201,524,251 - 1,548,473 (-)NCBI
RefSeq Acc Id: XM_055104722   ⟹   XP_054960697
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2212,399,937 - 2,432,330 (-)NCBI
NHGRI_mPanPan1202,396,766 - 2,426,602 (-)NCBI
RefSeq Acc Id: XM_055104723   ⟹   XP_054960698
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2212,399,937 - 2,429,079 (-)NCBI
NHGRI_mPanPan1202,396,766 - 2,425,907 (-)NCBI
Protein Sequences
Protein RefSeqs XP_034802788 (Get FASTA)   NCBI Sequence Viewer  
  XP_034802790 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960697 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960698 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000005044.1
  ENSPPAP00000039424.1
RefSeq Acc Id: XP_034802788   ⟸   XM_034946897
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034802790   ⟸   XM_034946899
- Peptide Label: isoform X4
- UniProtKB: A0A2R9CC16 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054960697   ⟸   XM_055104722
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054960698   ⟸   XM_055104723
- Peptide Label: isoform X3
Protein Domains
PPIase FKBP-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000021033 ENTREZGENE, UniProtKB/TrEMBL
  ENSPPAG00000042416 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000023066.1 UniProtKB/TrEMBL
  ENSPPAT00000062335.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.50.40 UniProtKB/TrEMBL
InterPro FKBP-type_PPIase UniProtKB/TrEMBL
  PPIase_dom_sf UniProtKB/TrEMBL
  PPIase_FKBP_dom UniProtKB/TrEMBL
NCBI Gene FKBP1A ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE UniProtKB/TrEMBL
  PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A-RELATED UniProtKB/TrEMBL
Pfam FKBP_C UniProtKB/TrEMBL
PROSITE FKBP_PPIASE UniProtKB/TrEMBL
Superfamily-SCOP FKBP-like UniProtKB/TrEMBL
UniProt A0A2R8ZK58_PANPA UniProtKB/TrEMBL
  A0A2R9CC16 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-06 FKBP1A  FKBP prolyl isomerase 1A    FK506 binding protein 1A  Symbol and/or name change 5135510 APPROVED