Ralgapa2 (Ral GTPase activating protein catalytic subunit alpha 2) - Rat Genome Database

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Gene: Ralgapa2 (Ral GTPase activating protein catalytic subunit alpha 2) Rattus norvegicus
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Symbol: Ralgapa2
Name: Ral GTPase activating protein catalytic subunit alpha 2
RGD ID: 1308023
Description: Enables GTPase activator activity and protein heterodimerization activity. Involved in activation of GTPase activity. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 250 kDa substrate of Akt; AS250; LOC296211; p220; Ral GTPase activating protein catalytic alpha subunit 2; Ral GTPase activating protein, alpha subunit 2 (catalytic); Ral GTPase-activating protein alpha subunit 2; ral GTPase-activating protein subunit alpha-2; RGD1308023; similar to CG5521-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83154,112,005 - 154,392,070 (-)NCBIGRCr8
mRatBN7.23133,658,725 - 133,938,821 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03140,451,850 - 140,728,305 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03146,870,901 - 147,146,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43134,867,846 - 135,145,583 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13134,893,509 - 134,996,492 (-)NCBI
Celera3132,526,330 - 132,803,310 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ralgapa2Ratfamilial hyperinsulinemic hypoglycemia 1  ISORGD:13439558554872ClinVar Annotator: match by term: Hyperinsulinemic hypoglycemia, familial, 1ClinVarPMID:38605124

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Object Symbol
Species
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Reference
Notes
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Original Reference(s)
Ralgapa2Rat(-)-epigallocatechin 3-gallate multiple interactionsISORGD:13439556480464[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of RALGAPA2 mRNACTDPMID:22079256
Ralgapa2Rat(1->4)-beta-D-glucan multiple interactionsISORGD:13175526480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of RALGAPA2 mRNACTDPMID:36331819
Ralgapa2Rat1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactionsISORGD:13175526480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
Ralgapa2Rat1,2-dimethylhydrazine decreases expressionISORGD:131755264804641,2-Dimethylhydrazine results in decreased expression of RALGAPA2 mRNACTDPMID:22206623
Ralgapa2Rat17beta-estradiol multiple interactionsISORGD:13439556480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of RALGAPA2 mRNACTDPMID:30165855
Ralgapa2Rat17beta-estradiol decreases expressionISORGD:13175526480464Estradiol results in decreased expression of RALGAPA2 mRNACTDPMID:39298647
Ralgapa2Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of RALGAPA2 mRNACTDPMID:32145629
Ralgapa2Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISORGD:13175526480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
Ralgapa2Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISORGD:13175526480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
Ralgapa2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:13439556480464Tetrachlorodibenzodioxin results in increased expression of RALGAPA2 mRNACTDPMID:26238291
Ralgapa2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of RALGAPA2 mRNACTDPMID:33387578
Ralgapa2Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642,3,7,8-tetrachlorodibenzofuran results in decreased expression of RALGAPA2 mRNACTDPMID:32109520
Ralgapa2Rat2,4,4'-trichlorobiphenyl multiple interactionsISORGD:13175526480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
Ralgapa2Rat2,5-hexanedione increases expressionEXP 64804642,5-hexanedione results in increased expression of RALGAPA2 mRNACTDPMID:22952946
Ralgapa2Rat2-hydroxypropanoic acid decreases expressionISORGD:13439556480464Lactic Acid results in decreased expression of RALGAPA2 mRNACTDPMID:30851411
Ralgapa2Rat3-methylcholanthrene multiple interactionsISORGD:13439556480464Methylcholanthrene promotes the reaction [AHR protein binds to RALGAPA2 promoter]CTDPMID:20348232
Ralgapa2Rat4,4'-sulfonyldiphenol decreases expressionISORGD:13175526480464bisphenol S results in decreased expression of RALGAPA2 mRNACTDPMID:39298647
Ralgapa2Rataflatoxin B1 increases methylationISORGD:13439556480464Aflatoxin B1 results in increased methylation of RALGAPA2 geneCTDPMID:28458013
Ralgapa2Rataflatoxin B1 decreases methylationISORGD:13439556480464Aflatoxin B1 results in decreased methylation of RALGAPA2 geneCTDPMID:27153756
Ralgapa2Ratantirheumatic drug increases expressionISORGD:13439556480464Antirheumatic Agents results in increased expression of RALGAPA2 mRNACTDPMID:24449571

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Biological Process
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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ralgapa2Ratactivation of GTPase activity involved_inIDA 8553279PMID:19520869UniProt 
Ralgapa2Ratactivation of GTPase activity acts_upstream_of_or_withinISORGD:13175521624291MGI:2444531 PMID:21148297RGDPMID:21148297
Ralgapa2RatRal protein signal transduction acts_upstream_of_or_withinISORGD:13175521624291 PMID:21148297RGDPMID:21148297
Ralgapa2RatRal protein signal transduction acts_upstream_of_or_withinIEAUniProtKB:A3KGS3|ensembl:ENSMUSP000001220391600115GO_REF:0000107EnsemblGO_REF:0000107
Ralgapa2Ratregulation of exocyst localization acts_upstream_of_or_withinIEAUniProtKB:A3KGS3|ensembl:ENSMUSP000001220391600115GO_REF:0000107EnsemblGO_REF:0000107
Ralgapa2Ratregulation of exocyst localization acts_upstream_of_or_withinISORGD:13175521624291 PMID:21148297RGDPMID:21148297
Ralgapa2Ratregulation of protein localization acts_upstream_of_or_withinISORGD:13175521624291 PMID:21148297RGDPMID:21148297
Ralgapa2Ratregulation of protein localization acts_upstream_of_or_withinIEAUniProtKB:A3KGS3|ensembl:ENSMUSP000001220391600115GO_REF:0000107EnsemblGO_REF:0000107
Ralgapa2Ratregulation of small GTPase mediated signal transduction involved_inIEAInterPro:IPR000331|InterPro:IPR0359741600115GO_REF:0000002InterProGO_REF:0000002
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Cellular Component
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Object Symbol
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Evidence
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Reference
Notes
Source
Original Reference(s)
Ralgapa2Ratcytoplasm located_inISSUniProtKB:Q2PPJ71600115GO_REF:0000024UniProtGO_REF:0000024
Ralgapa2Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Ralgapa2Ratcytoplasm located_inIEAUniProtKB:Q2PPJ7|ensembl:ENSP000002026771600115GO_REF:0000107EnsemblGO_REF:0000107
Ralgapa2Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Ralgapa2Ratcytoplasm is_active_inIBAFB:FBgn0005198|MGI:102548|MGI:1931050|PANTHER:PTN000006939|PomBase:SPAC630.13c|RGD:3908|UniProtKB:P49815|UniProtKB:Q2PPJ71600115GO_REF:0000033GO_CentralGO_REF:0000033
Ralgapa2Ratcytoplasm located_inISORGD:13439551624291 PMID:16490346RGDPMID:16490346
Ralgapa2Ratcytosol located_inIEAUniProtKB:Q2PPJ7|ensembl:ENSP000002026771600115GO_REF:0000107EnsemblGO_REF:0000107
Ralgapa2Ratcytosol located_inISORGD:1343955|UniProtKB:Q2PPJ7-11624291 RGDGO_REF:0000052
Ralgapa2Ratnucleus located_inIEAInterPro:IPR0271071600115GO_REF:0000002InterProGO_REF:0000002
Ralgapa2Ratplasma membrane located_inIEAUniProtKB:Q2PPJ7|ensembl:ENSP000002026771600115GO_REF:0000107EnsemblGO_REF:0000107
Ralgapa2Ratplasma membrane located_inISORGD:1343955|UniProtKB:Q2PPJ7-11624291 RGDGO_REF:0000052
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Molecular Function
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Object Symbol
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Term
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Evidence
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Reference
Notes
Source
Original Reference(s)
Ralgapa2RatGTPase activator activity enablesIEAUniRule:UR0004152101600115GO_REF:0000104UniProtGO_REF:0000104
Ralgapa2RatGTPase activator activity enablesISORGD:13175521624291MGI:2444531 PMID:21148297RGDPMID:21148297
Ralgapa2RatGTPase activator activity enablesIEAUniProtKB:A3KGS3|ensembl:ENSMUSP000001220391600115GO_REF:0000107EnsemblGO_REF:0000107
Ralgapa2RatGTPase activator activity enablesIBAFB:FBgn0005198|MGI:102548|MGI:3036245|PANTHER:PTN000006939|PomBase:SPAC630.13c|RGD:1308023|RGD:3908|UniProtKB:P498151600115GO_REF:0000033GO_CentralGO_REF:0000033
Ralgapa2RatGTPase activator activity enablesIEAInterPro:IPR000331|InterPro:IPR027107|InterPro:IPR0359741600115GO_REF:0000002InterProGO_REF:0000002
Ralgapa2RatGTPase activator activity enablesIEAUniProtKB-KW:KW-03431600115GO_REF:0000043UniProtGO_REF:0000043
Ralgapa2RatGTPase activator activity enablesIDA 8553279PMID:19520869UniProt 
Ralgapa2Ratprotein binding enablesISORGD:13439551624291UniProtKB:Q8WTU0 PMID:32296183RGDPMID:32296183
Ralgapa2Ratprotein binding enablesISORGD:13175521624291PR:Q8CEC5|PR:Q9CR56 PMID:25220458RGDPMID:25220458
Ralgapa2Ratprotein heterodimerization activity enablesIPIUniProtKB:P864108553279PMID:19520869UniProt 
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases. Shirakawa R, etal., J Biol Chem. 2009 Aug 7;284(32):21580-8. doi: 10.1074/jbc.M109.012112. Epub 2009 Jun 11.
PMID:15057822   PMID:15632090   PMID:16490346   PMID:21148297   PMID:22664934  



Ralgapa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83154,112,005 - 154,392,070 (-)NCBIGRCr8
mRatBN7.23133,658,725 - 133,938,821 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03140,451,850 - 140,728,305 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03146,870,901 - 147,146,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43134,867,846 - 135,145,583 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13134,893,509 - 134,996,492 (-)NCBI
Celera3132,526,330 - 132,803,310 (-)NCBICelera
Cytogenetic Map3q41NCBI
RALGAPA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382020,389,530 - 20,712,644 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2020,389,530 - 20,712,644 (-)EnsemblGRCh38hg38GRCh38
GRCh372020,370,174 - 20,693,287 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362020,321,411 - 20,641,266 (-)NCBINCBI36Build 36hg18NCBI36
Celera2020,447,485 - 20,767,346 (-)NCBICelera
Cytogenetic Map20p11.23NCBI
HuRef2020,333,630 - 20,656,842 (-)NCBIHuRef
CHM1_12020,370,712 - 20,693,651 (-)NCBICHM1_1
T2T-CHM13v2.02020,448,061 - 20,771,350 (-)NCBIT2T-CHM13v2.0
Ralgapa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392146,079,326 - 146,354,174 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2146,081,799 - 146,354,264 (-)EnsemblGRCm39 Ensembl
GRCm382146,239,876 - 146,512,254 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2146,239,879 - 146,512,344 (-)EnsemblGRCm38mm10GRCm38
MGSCv372146,067,032 - 146,337,740 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362146,120,893 - 146,203,447 (-)NCBIMGSCv36mm8
Celera2147,474,453 - 147,748,942 (-)NCBICelera
Cytogenetic Map2G1NCBI
cM Map271.33NCBI
Ralgapa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541528,414,386 - 28,663,485 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541528,414,856 - 28,663,485 (-)NCBIChiLan1.0ChiLan1.0
RALGAPA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,268,175 - 21,594,631 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12021,267,629 - 21,591,448 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02020,338,629 - 20,662,926 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12020,299,568 - 20,625,458 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2020,299,638 - 20,625,443 (-)Ensemblpanpan1.1panPan2
RALGAPA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,665,950 - 2,992,779 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,676,461 - 2,989,864 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha242,694,032 - 3,021,021 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0243,073,282 - 3,400,603 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl243,083,818 - 3,398,194 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1242,670,124 - 2,996,986 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0242,773,127 - 3,100,047 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0243,051,017 - 3,378,081 (+)NCBIUU_Cfam_GSD_1.0
Ralgapa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640151,333,758 - 151,615,951 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049372858,016 - 105,025 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049372857,705 - 105,200 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGAPA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1728,408,099 - 28,679,231 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11728,408,096 - 28,679,231 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21732,010,888 - 32,135,505 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGAPA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1249,381,251 - 49,704,946 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl249,465,647 - 49,645,287 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660784,168,451 - 4,496,449 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ralgapa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474120,885,215 - 21,171,787 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474120,889,913 - 21,171,787 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ralgapa2
1106 total Variants

Predicted Target Of
Summary Value
Count of predictions:16
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000015637
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


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The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat

1 to 10 of 33 rows
D3Rat215  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83154,367,513 - 154,367,746 (+)Marker Load Pipeline
Rnor_6.03140,703,784 - 140,704,003NCBIRnor6.0
Rnor_5.03147,122,482 - 147,122,701UniSTSRnor5.0
RGSC_v3.43135,120,846 - 135,121,076RGDRGSC3.4
RGSC_v3.43135,120,844 - 135,121,076UniSTSRGSC3.4
RGSC_v3.13135,026,419 - 135,026,649RGD
Celera3132,778,800 - 132,779,032UniSTS
SHRSP x BN Map364.1499RGD
SHRSP x BN Map364.1499UniSTS
Cytogenetic Map3q41UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 21 of 21 rows
RefSeq Transcripts NM_001421313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 21 of 21 rows

Ensembl Acc Id: ENSRNOT00000015637   ⟹   ENSRNOP00000015637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,678,482 - 133,938,727 (-)Ensembl
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094218   ⟹   ENSRNOP00000080653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106826   ⟹   ENSRNOP00000093785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113019   ⟹   ENSRNOP00000084183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
RefSeq Acc Id: NM_001421313   ⟹   NP_001408242
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,047 (-)NCBI
mRatBN7.23133,658,725 - 133,938,797 (-)NCBI
RefSeq Acc Id: XM_017592238   ⟹   XP_017447727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,070 (-)NCBI
mRatBN7.23133,661,955 - 133,938,820 (-)NCBI
Rnor_6.03140,451,850 - 140,728,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039106622   ⟹   XP_038962550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,209,810 - 154,392,070 (-)NCBI
mRatBN7.23133,756,535 - 133,938,821 (-)NCBI
RefSeq Acc Id: XM_039106623   ⟹   XP_038962551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,988 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XM_039106624   ⟹   XP_038962552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,988 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XM_063283347   ⟹   XP_063139417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,070 (-)NCBI
RefSeq Acc Id: XM_063283348   ⟹   XP_063139418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,069 (-)NCBI
RefSeq Acc Id: XM_063283349   ⟹   XP_063139419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,069 (-)NCBI
RefSeq Acc Id: XM_063283350   ⟹   XP_063139420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,378,785 (-)NCBI
RefSeq Acc Id: XM_063283352   ⟹   XP_063139422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,292,812 (-)NCBI
RefSeq Acc Id: XM_063283353   ⟹   XP_063139423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,283,873 (-)NCBI
RefSeq Acc Id: XR_005502527
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,230,860 - 154,392,069 (-)NCBI
mRatBN7.23133,773,811 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_005502528
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,980 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_005502529
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,980 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_010064588
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,231,124 - 154,392,069 (-)NCBI
1 to 5 of 15 rows
1 to 5 of 15 rows
RefSeq Acc Id: XP_017447727   ⟸   XM_017592238
- Peptide Label: isoform X1
- UniProtKB: P86411 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015637   ⟸   ENSRNOT00000015637
RefSeq Acc Id: XP_038962550   ⟸   XM_039106622
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038962552   ⟸   XM_039106624
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038962551   ⟸   XM_039106623
- Peptide Label: isoform X7
Rap-GAP

Name Modeler Protein Id AA Range Protein Structure
AF-P86411-F1-model_v2 AlphaFold P86411 1-1872 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-47571 BioCyc
Ensembl Genes ENSRNOG00000036964 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000094218 ENTREZGENE
  ENSRNOT00000106826 ENTREZGENE
  ENSRNOT00000113019.1 UniProtKB/Swiss-Prot
  ENSRNOT00000125212 ENTREZGENE
Gene3D-CATH 3.40.50.11210 UniProtKB/Swiss-Prot
InterPro ARM-type_fold UniProtKB/Swiss-Prot
  Rap/Ran-GAP_sf UniProtKB/Swiss-Prot
  Rap_GAP_dom UniProtKB/Swiss-Prot
  RGPA/RALGAPB_N UniProtKB/Swiss-Prot
  Tuberin/Ral-act_asu UniProtKB/Swiss-Prot
NCBI Gene 296211 ENTREZGENE
PANTHER PTHR10063 UniProtKB/Swiss-Prot
  RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-2 UniProtKB/Swiss-Prot
Pfam RALGAPB_N UniProtKB/Swiss-Prot
  Rap_GAP UniProtKB/Swiss-Prot
PhenoGen Ralgapa2 PhenoGen
PROSITE RAPGAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000036964 RatGTEx
Superfamily-SCOP SSF111347 UniProtKB/Swiss-Prot
  SSF48371 UniProtKB/Swiss-Prot
UniProt A0A8I6AGG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G4U3 ENTREZGENE, UniProtKB/TrEMBL
  A6K791 ENTREZGENE, UniProtKB/TrEMBL
  D3ZKI6_RAT UniProtKB/TrEMBL
  P86411 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Ralgapa2  Ral GTPase activating protein catalytic subunit alpha 2  Ralgapa2  Ral GTPase activating protein catalytic alpha subunit 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Ralgapa2  Ral GTPase activating protein catalytic alpha subunit 2  Ralgapa2  Ral GTPase activating protein, alpha subunit 2 (catalytic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-10 Ralgapa2  Ral GTPase activating protein, alpha subunit 2 (catalytic)  RGD1308023  similar to CG5521-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1308023  similar to CG5521-PA   RGD1308023_predicted  similar to CG5521-PA (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308023_predicted  similar to CG5521-PA (predicted)  LOC296211_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC296211_predicted  similar to CG5521-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL