Ralgapa2 (Ral GTPase activating protein catalytic subunit alpha 2) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Ralgapa2 (Ral GTPase activating protein catalytic subunit alpha 2) Rattus norvegicus
Analyze
Symbol: Ralgapa2
Name: Ral GTPase activating protein catalytic subunit alpha 2
RGD ID: 1308023
Description: Enables GTPase activator activity and protein heterodimerization activity. Involved in activation of GTPase activity. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 250 kDa substrate of Akt; AS250; LOC296211; p220; Ral GTPase activating protein catalytic alpha subunit 2; Ral GTPase activating protein, alpha subunit 2 (catalytic); Ral GTPase-activating protein alpha subunit 2; ral GTPase-activating protein subunit alpha-2; RGD1308023; similar to CG5521-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83154,112,005 - 154,392,070 (-)NCBIGRCr8
mRatBN7.23133,658,725 - 133,938,821 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03140,451,850 - 140,728,305 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03146,870,901 - 147,146,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43134,867,846 - 135,145,583 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13134,893,509 - 134,996,492 (-)NCBI
Celera3132,526,330 - 132,803,310 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,5-hexanedione  (EXP)
2-hydroxypropanoic acid  (ISO)
3-methylcholanthrene  (ISO)
aflatoxin B1  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
calcitriol  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
Dibutyl phosphate  (ISO)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
FR900359  (ISO)
hexadecanoic acid  (ISO)
leflunomide  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
Monobutylphthalate  (EXP)
N,N-diethyl-m-toluamide  (EXP)
nickel sulfate  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP)
potassium chromate  (ISO)
propanal  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetraphene  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO,ISS)
cytosol  (IEA,ISO)
nucleus  (IEA)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases. Shirakawa R, etal., J Biol Chem. 2009 Aug 7;284(32):21580-8. doi: 10.1074/jbc.M109.012112. Epub 2009 Jun 11.
Additional References at PubMed
PMID:15057822   PMID:15632090   PMID:16490346   PMID:21148297   PMID:22664934  


Genomics

Comparative Map Data
Ralgapa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83154,112,005 - 154,392,070 (-)NCBIGRCr8
mRatBN7.23133,658,725 - 133,938,821 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03140,451,850 - 140,728,305 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03146,870,901 - 147,146,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43134,867,846 - 135,145,583 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13134,893,509 - 134,996,492 (-)NCBI
Celera3132,526,330 - 132,803,310 (-)NCBICelera
Cytogenetic Map3q41NCBI
RALGAPA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382020,389,530 - 20,712,644 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2020,389,530 - 20,712,644 (-)EnsemblGRCh38hg38GRCh38
GRCh372020,370,174 - 20,693,287 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362020,321,411 - 20,641,266 (-)NCBINCBI36Build 36hg18NCBI36
Celera2020,447,485 - 20,767,346 (-)NCBICelera
Cytogenetic Map20p11.23NCBI
HuRef2020,333,630 - 20,656,842 (-)NCBIHuRef
CHM1_12020,370,712 - 20,693,651 (-)NCBICHM1_1
T2T-CHM13v2.02020,448,061 - 20,771,350 (-)NCBIT2T-CHM13v2.0
Ralgapa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392146,079,326 - 146,354,174 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2146,081,799 - 146,354,264 (-)EnsemblGRCm39 Ensembl
GRCm382146,239,876 - 146,512,254 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2146,239,879 - 146,512,344 (-)EnsemblGRCm38mm10GRCm38
MGSCv372146,067,032 - 146,337,740 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362146,120,893 - 146,203,447 (-)NCBIMGSCv36mm8
Celera2147,474,453 - 147,748,942 (-)NCBICelera
Cytogenetic Map2G1NCBI
cM Map271.33NCBI
Ralgapa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541528,414,386 - 28,663,485 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541528,414,856 - 28,663,485 (-)NCBIChiLan1.0ChiLan1.0
RALGAPA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,268,175 - 21,594,631 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12021,267,629 - 21,591,448 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02020,338,629 - 20,662,926 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12020,299,568 - 20,625,458 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2020,299,638 - 20,625,443 (-)Ensemblpanpan1.1panPan2
RALGAPA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,665,950 - 2,992,779 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,676,461 - 2,989,864 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha242,694,032 - 3,021,021 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0243,073,282 - 3,400,603 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl243,083,818 - 3,398,194 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1242,670,124 - 2,996,986 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0242,773,127 - 3,100,047 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0243,051,017 - 3,378,081 (+)NCBIUU_Cfam_GSD_1.0
Ralgapa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640151,333,758 - 151,615,951 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049372858,016 - 105,025 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049372857,705 - 105,200 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGAPA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1728,408,099 - 28,679,231 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11728,408,096 - 28,679,231 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21732,010,888 - 32,135,505 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGAPA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1249,381,251 - 49,704,946 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl249,465,647 - 49,645,287 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660784,168,451 - 4,496,449 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ralgapa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474120,885,215 - 21,171,787 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474120,889,913 - 21,171,787 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ralgapa2
1106 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:16
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000015637
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1581546Pur13Proteinuria QTL 132.930.0335urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat

Markers in Region
D3Rat215  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83154,367,513 - 154,367,746 (+)Marker Load Pipeline
Rnor_6.03140,703,784 - 140,704,003NCBIRnor6.0
Rnor_5.03147,122,482 - 147,122,701UniSTSRnor5.0
RGSC_v3.43135,120,846 - 135,121,076RGDRGSC3.4
RGSC_v3.43135,120,844 - 135,121,076UniSTSRGSC3.4
RGSC_v3.13135,026,419 - 135,026,649RGD
Celera3132,778,800 - 132,779,032UniSTS
SHRSP x BN Map364.1499RGD
SHRSP x BN Map364.1499UniSTS
Cytogenetic Map3q41UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001421313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283350 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010064588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000015637   ⟹   ENSRNOP00000015637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,678,482 - 133,938,727 (-)Ensembl
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094218   ⟹   ENSRNOP00000080653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106826   ⟹   ENSRNOP00000093785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113019   ⟹   ENSRNOP00000084183
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
RefSeq Acc Id: NM_001421313   ⟹   NP_001408242
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,047 (-)NCBI
mRatBN7.23133,658,725 - 133,938,797 (-)NCBI
RefSeq Acc Id: XM_017592238   ⟹   XP_017447727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,070 (-)NCBI
mRatBN7.23133,661,955 - 133,938,820 (-)NCBI
Rnor_6.03140,451,850 - 140,728,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039106622   ⟹   XP_038962550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,209,810 - 154,392,070 (-)NCBI
mRatBN7.23133,756,535 - 133,938,821 (-)NCBI
RefSeq Acc Id: XM_039106623   ⟹   XP_038962551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,988 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XM_039106624   ⟹   XP_038962552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,988 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XM_063283347   ⟹   XP_063139417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,070 (-)NCBI
RefSeq Acc Id: XM_063283348   ⟹   XP_063139418
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,069 (-)NCBI
RefSeq Acc Id: XM_063283349   ⟹   XP_063139419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,392,069 (-)NCBI
RefSeq Acc Id: XM_063283350   ⟹   XP_063139420
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,378,785 (-)NCBI
RefSeq Acc Id: XM_063283352   ⟹   XP_063139422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,292,812 (-)NCBI
RefSeq Acc Id: XM_063283353   ⟹   XP_063139423
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,112,005 - 154,283,873 (-)NCBI
RefSeq Acc Id: XR_005502527
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,230,860 - 154,392,069 (-)NCBI
mRatBN7.23133,773,811 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_005502528
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,980 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_005502529
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,221,980 - 154,392,069 (-)NCBI
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_010064588
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83154,231,124 - 154,392,069 (-)NCBI
RefSeq Acc Id: XP_017447727   ⟸   XM_017592238
- Peptide Label: isoform X1
- UniProtKB: P86411 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000015637   ⟸   ENSRNOT00000015637
RefSeq Acc Id: XP_038962550   ⟸   XM_039106622
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038962552   ⟸   XM_039106624
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038962551   ⟸   XM_039106623
- Peptide Label: isoform X7
Ensembl Acc Id: ENSRNOP00000093785   ⟸   ENSRNOT00000106826
Ensembl Acc Id: ENSRNOP00000080653   ⟸   ENSRNOT00000094218
Ensembl Acc Id: ENSRNOP00000084183   ⟸   ENSRNOT00000113019
RefSeq Acc Id: NP_001408242   ⟸   NM_001421313
- UniProtKB: P86411 (UniProtKB/Swiss-Prot),   A0A8I6G4U3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139417   ⟸   XM_063283347
- Peptide Label: isoform X2
- UniProtKB: P86411 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063139418   ⟸   XM_063283348
- Peptide Label: isoform X3
- UniProtKB: P86411 (UniProtKB/Swiss-Prot),   A0A8I6AGG2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139419   ⟸   XM_063283349
- Peptide Label: isoform X4
- UniProtKB: P86411 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063139420   ⟸   XM_063283350
- Peptide Label: isoform X5
- UniProtKB: P86411 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063139422   ⟸   XM_063283352
- Peptide Label: isoform X9
- UniProtKB: A6K791 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139423   ⟸   XM_063283353
- Peptide Label: isoform X10
- UniProtKB: A6K791 (UniProtKB/TrEMBL)
Protein Domains
Rap-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P86411-F1-model_v2 AlphaFold P86411 1-1872 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308023 AgrOrtholog
BioCyc Gene G2FUF-47571 BioCyc
Ensembl Genes ENSRNOG00000036964 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015637.8 UniProtKB/TrEMBL
  ENSRNOT00000094218.1 UniProtKB/TrEMBL
  ENSRNOT00000106826.1 UniProtKB/TrEMBL
  ENSRNOT00000113019.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.11210 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap/Ran-GAP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap_GAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGPA/RALGAPB_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tuberin/Ral-act_asu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 296211 ENTREZGENE
PANTHER PTHR10063 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RALGAPB_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap_GAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ralgapa2 PhenoGen
PROSITE RAPGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000036964 RatGTEx
Superfamily-SCOP SSF111347 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AGG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G4U3 ENTREZGENE, UniProtKB/TrEMBL
  A6K791 ENTREZGENE, UniProtKB/TrEMBL
  D3ZKI6_RAT UniProtKB/TrEMBL
  P86411 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Ralgapa2  Ral GTPase activating protein catalytic subunit alpha 2  Ralgapa2  Ral GTPase activating protein catalytic alpha subunit 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Ralgapa2  Ral GTPase activating protein catalytic alpha subunit 2  Ralgapa2  Ral GTPase activating protein, alpha subunit 2 (catalytic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-10 Ralgapa2  Ral GTPase activating protein, alpha subunit 2 (catalytic)  RGD1308023  similar to CG5521-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1308023  similar to CG5521-PA   RGD1308023_predicted  similar to CG5521-PA (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308023_predicted  similar to CG5521-PA (predicted)  LOC296211_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC296211_predicted  similar to CG5521-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL