Ralgapa2 (Ral GTPase activating protein catalytic subunit alpha 2) - Rat Genome Database

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Gene: Ralgapa2 (Ral GTPase activating protein catalytic subunit alpha 2) Rattus norvegicus
Analyze
Symbol: Ralgapa2
Name: Ral GTPase activating protein catalytic subunit alpha 2
RGD ID: 1308023
Description: Enables GTPase activator activity and protein heterodimerization activity. Involved in activation of GTPase activity. Predicted to be located in cytosol and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human RALGAPA2 (Ral GTPase activating protein catalytic subunit alpha 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,5-hexanedione.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 250 kDa substrate of Akt; AS250; LOC296211; p220; Ral GTPase activating protein catalytic alpha subunit 2; Ral GTPase activating protein, alpha subunit 2 (catalytic); Ral GTPase-activating protein alpha subunit 2; ral GTPase-activating protein subunit alpha-2; RGD1308023; similar to CG5521-PA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23133,661,955 - 133,938,821 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
Rnor_6.03140,451,850 - 140,728,305 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03146,870,901 - 147,146,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43134,867,846 - 135,145,583 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13134,893,509 - 134,996,492 (-)NCBI
Celera3132,526,330 - 132,803,310 (-)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO,ISS)
cytosol  (ISO)
nucleus  (IEA)
plasma membrane  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases. Shirakawa R, etal., J Biol Chem. 2009 Aug 7;284(32):21580-8. doi: 10.1074/jbc.M109.012112. Epub 2009 Jun 11.
Additional References at PubMed
PMID:15057822   PMID:15632090   PMID:16490346   PMID:21148297   PMID:22664934  


Genomics

Comparative Map Data
Ralgapa2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23133,661,955 - 133,938,821 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
Rnor_6.03140,451,850 - 140,728,305 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03146,870,901 - 147,146,723 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43134,867,846 - 135,145,583 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13134,893,509 - 134,996,492 (-)NCBI
Celera3132,526,330 - 132,803,310 (-)NCBICelera
Cytogenetic Map3q41NCBI
RALGAPA2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382020,389,530 - 20,712,644 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2020,389,530 - 20,712,644 (-)EnsemblGRCh38hg38GRCh38
GRCh372020,370,174 - 20,693,287 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362020,321,411 - 20,641,266 (-)NCBINCBI36hg18NCBI36
Celera2020,447,485 - 20,767,346 (-)NCBI
Cytogenetic Map20p11.23NCBI
HuRef2020,333,630 - 20,656,842 (-)NCBIHuRef
CHM1_12020,370,712 - 20,693,651 (-)NCBICHM1_1
T2T-CHM13v2.02020,448,061 - 20,771,350 (-)NCBI
Ralgapa2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392146,081,796 - 146,354,174 (-)NCBIGRCm39mm39
GRCm39 Ensembl2146,081,799 - 146,354,264 (-)Ensembl
GRCm382146,239,876 - 146,512,254 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2146,239,879 - 146,512,344 (-)EnsemblGRCm38mm10GRCm38
MGSCv372146,067,032 - 146,337,740 (-)NCBIGRCm37mm9NCBIm37
MGSCv362146,120,893 - 146,203,447 (-)NCBImm8
Celera2147,474,453 - 147,748,942 (-)NCBICelera
Cytogenetic Map2G1NCBI
Ralgapa2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541528,414,386 - 28,663,485 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541528,414,856 - 28,663,485 (-)NCBIChiLan1.0ChiLan1.0
RALGAPA2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12020,299,568 - 20,625,458 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2020,299,638 - 20,625,443 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02020,338,629 - 20,662,926 (-)NCBIMhudiblu_PPA_v0panPan3
RALGAPA2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,665,950 - 2,992,779 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,676,461 - 2,989,864 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha242,694,032 - 3,021,021 (+)NCBI
ROS_Cfam_1.0243,073,282 - 3,400,603 (+)NCBI
ROS_Cfam_1.0 Ensembl243,083,818 - 3,398,194 (+)Ensembl
UMICH_Zoey_3.1242,670,124 - 2,996,986 (+)NCBI
UNSW_CanFamBas_1.0242,773,127 - 3,100,047 (+)NCBI
UU_Cfam_GSD_1.0243,051,017 - 3,378,081 (+)NCBI
Ralgapa2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640151,333,758 - 151,615,951 (+)NCBI
SpeTri2.0NW_0049372857,705 - 105,200 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGAPA2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1728,408,099 - 28,679,231 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11728,408,096 - 28,679,231 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21732,010,888 - 32,135,505 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGAPA2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1249,381,251 - 49,704,946 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl249,465,647 - 49,645,287 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660784,168,451 - 4,496,449 (-)NCBIVero_WHO_p1.0
Ralgapa2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474120,885,215 - 21,171,787 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474120,889,913 - 21,171,787 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D3Rat215  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.03140,703,784 - 140,704,003NCBIRnor6.0
Rnor_5.03147,122,482 - 147,122,701UniSTSRnor5.0
RGSC_v3.43135,120,846 - 135,121,076RGDRGSC3.4
RGSC_v3.43135,120,844 - 135,121,076UniSTSRGSC3.4
RGSC_v3.13135,026,419 - 135,026,649RGD
Celera3132,778,800 - 132,779,032UniSTS
SHRSP x BN Map364.1499UniSTS
SHRSP x BN Map364.1499RGD
Cytogenetic Map3q41UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1581546Pur13Proteinuria QTL 132.930.0335total urine protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)378196190146592722Rat
631649Bp123Blood pressure QTL 1233.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)389772419134772419Rat
8694437Bw167Body weight QTL 16722.460.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)391797474136797474Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
724532Cm17Cardiac mass QTL 172heart mass (VT:0007028)calculated heart weight (CMO:0000073)395735366140735366Rat
1354611Despr2Despair related QTL 23.030.0028locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)397084464142084464Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)397551417147415807Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1331758Bp207Blood pressure QTL 2072.848arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3112287552135181505Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)3115638168135181505Rat
1358204Insglur1Insulin/glucose ratio QTL 13.8blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)3115638168135181505Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1300173Rf11Renal function QTL 113.38renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)3121056165145956249Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:16
Count of miRNA genes:15
Interacting mature miRNAs:15
Transcripts:ENSRNOT00000015637
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 14 24 10 16 10 1 1 43 21 15 11 1
Low 1 29 33 31 3 31 7 10 31 14 26 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_008762288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008775554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106625 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106626 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005502529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000015637   ⟹   ENSRNOP00000015637
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,678,482 - 133,938,727 (-)Ensembl
Rnor_6.0 Ensembl3140,468,701 - 140,728,129 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094218   ⟹   ENSRNOP00000080653
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000106826   ⟹   ENSRNOP00000093785
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113019   ⟹   ENSRNOP00000084183
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3133,659,761 - 133,938,916 (-)Ensembl
RefSeq Acc Id: XM_008762288   ⟹   XP_008760510
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,668,869 - 133,938,820 (-)NCBI
Rnor_6.03140,467,699 - 140,728,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008762289   ⟹   XP_008760511
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,668,871 - 133,938,820 (-)NCBI
Rnor_6.03140,467,699 - 140,728,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592238   ⟹   XP_017447727
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,661,955 - 133,938,820 (-)NCBI
Rnor_6.03140,451,850 - 140,728,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592239   ⟹   XP_017447728
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,668,870 - 133,938,820 (-)NCBI
Rnor_6.03140,467,699 - 140,728,305 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039106620   ⟹   XP_038962548
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,668,868 - 133,938,821 (-)NCBI
RefSeq Acc Id: XM_039106621   ⟹   XP_038962549
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,668,868 - 133,938,821 (-)NCBI
RefSeq Acc Id: XM_039106622   ⟹   XP_038962550
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,756,535 - 133,938,821 (-)NCBI
RefSeq Acc Id: XM_039106623   ⟹   XP_038962551
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XM_039106624   ⟹   XP_038962552
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XM_039106625   ⟹   XP_038962553
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,668,860 - 133,839,560 (-)NCBI
RefSeq Acc Id: XM_039106626   ⟹   XP_038962554
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,668,859 - 133,830,615 (-)NCBI
RefSeq Acc Id: XM_039106627   ⟹   XP_038962555
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,668,859 - 133,828,173 (-)NCBI
RefSeq Acc Id: XR_005502526
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,686,314 - 133,938,821 (-)NCBI
RefSeq Acc Id: XR_005502527
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,773,811 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_005502528
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
RefSeq Acc Id: XR_005502529
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23133,768,709 - 133,938,820 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_008760511   ⟸   XM_008762289
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_008760510   ⟸   XM_008762288
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017447727   ⟸   XM_017592238
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017447728   ⟸   XM_017592239
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000015637   ⟸   ENSRNOT00000015637
RefSeq Acc Id: XP_038962554   ⟸   XM_039106626
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038962555   ⟸   XM_039106627
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038962553   ⟸   XM_039106625
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038962549   ⟸   XM_039106621
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038962548   ⟸   XM_039106620
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038962550   ⟸   XM_039106622
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038962552   ⟸   XM_039106624
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038962551   ⟸   XM_039106623
- Peptide Label: isoform X8
RefSeq Acc Id: ENSRNOP00000093785   ⟸   ENSRNOT00000106826
RefSeq Acc Id: ENSRNOP00000080653   ⟸   ENSRNOT00000094218
RefSeq Acc Id: ENSRNOP00000084183   ⟸   ENSRNOT00000113019
Protein Domains
Rap-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P86411-F1-model_v2 AlphaFold P86411 1-1872 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308023 AgrOrtholog
BioCyc Gene G2FUF-47571 BioCyc
Ensembl Genes ENSRNOG00000036964 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000015637.8 UniProtKB/TrEMBL
  ENSRNOP00000080653.1 UniProtKB/TrEMBL
  ENSRNOP00000084183 UniProtKB/Swiss-Prot
  ENSRNOP00000093785 ENTREZGENE
  ENSRNOP00000093785.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015637.8 UniProtKB/TrEMBL
  ENSRNOT00000094218.1 UniProtKB/TrEMBL
  ENSRNOT00000106826 ENTREZGENE
  ENSRNOT00000106826.1 UniProtKB/TrEMBL
  ENSRNOT00000113019 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.11210 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap/Ran-GAP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap_GAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tuberin/Ral-act_asu UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 296211 ENTREZGENE
PANTHER PTHR10063 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Rap_GAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ralgapa2 PhenoGen
PROSITE RAPGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF111347 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AGG2_RAT UniProtKB/TrEMBL
  A0A8I6G4U3_RAT UniProtKB/TrEMBL
  D3ZKI6_RAT UniProtKB/TrEMBL
  P86411 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-06 Ralgapa2  Ral GTPase activating protein catalytic subunit alpha 2  Ralgapa2  Ral GTPase activating protein catalytic alpha subunit 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Ralgapa2  Ral GTPase activating protein catalytic alpha subunit 2  Ralgapa2  Ral GTPase activating protein, alpha subunit 2 (catalytic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-10 Ralgapa2  Ral GTPase activating protein, alpha subunit 2 (catalytic)  RGD1308023  similar to CG5521-PA  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1308023  similar to CG5521-PA   RGD1308023_predicted  similar to CG5521-PA (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308023_predicted  similar to CG5521-PA (predicted)  LOC296211_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC296211_predicted  similar to CG5521-PA (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL