Cyp2u1 (cytochrome P450, family 2, subfamily u, polypeptide 1) - Rat Genome Database

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Gene: Cyp2u1 (cytochrome P450, family 2, subfamily u, polypeptide 1) Rattus norvegicus
Analyze
Symbol: Cyp2u1
Name: cytochrome P450, family 2, subfamily u, polypeptide 1
RGD ID: 1309433
Description: Predicted to enable heme binding activity and monooxygenase activity. Predicted to be involved in omega-hydroxylase P450 pathway and xenobiotic metabolic process. Predicted to be located in endoplasmic reticulum membrane and mitochondrial inner membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 56. Orthologous to human CYP2U1 (cytochrome P450 family 2 subfamily U member 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cytochrome P450 2U1; LOC310848; long-chain fatty acid omega-monooxygenase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82222,523,516 - 222,541,055 (-)NCBIGRCr8
mRatBN7.22219,849,403 - 219,866,959 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2219,849,407 - 219,866,882 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2227,505,747 - 227,523,224 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02225,405,415 - 225,422,891 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02220,263,041 - 220,280,518 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02236,414,131 - 236,431,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2236,414,135 - 236,431,683 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02254,963,065 - 254,980,117 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42228,771,187 - 228,788,636 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12228,757,928 - 228,775,376 (-)NCBI
Celera2212,105,431 - 212,122,977 (-)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
amiodarone  (ISO)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
C60 fullerene  (EXP)
calcitriol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cyclosporin A  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
flusilazole  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
hydroquinone O-beta-D-glucopyranoside  (ISO)
leflunomide  (EXP)
mercury atom  (ISO)
mercury(0)  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
obeticholic acid  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (ISO)
propiconazole  (EXP,ISO)
silicon dioxide  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
toluene  (ISO)
triadimefon  (EXP)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:24563460  


Genomics

Comparative Map Data
Cyp2u1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82222,523,516 - 222,541,055 (-)NCBIGRCr8
mRatBN7.22219,849,403 - 219,866,959 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2219,849,407 - 219,866,882 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2227,505,747 - 227,523,224 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02225,405,415 - 225,422,891 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02220,263,041 - 220,280,518 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02236,414,131 - 236,431,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2236,414,135 - 236,431,683 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02254,963,065 - 254,980,117 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42228,771,187 - 228,788,636 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12228,757,928 - 228,775,376 (-)NCBI
Celera2212,105,431 - 212,122,977 (-)NCBICelera
Cytogenetic Map2q43NCBI
CYP2U1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384107,931,549 - 107,953,461 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4107,931,549 - 107,953,461 (+)EnsemblGRCh38hg38GRCh38
GRCh374108,852,705 - 108,874,617 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364109,072,166 - 109,094,062 (+)NCBINCBI36Build 36hg18NCBI36
Build 344109,210,368 - 109,231,027NCBI
Celera4106,147,507 - 106,169,403 (+)NCBICelera
Cytogenetic Map4q25NCBI
HuRef4104,584,305 - 104,606,201 (+)NCBIHuRef
CHM1_14108,829,176 - 108,851,087 (+)NCBICHM1_1
T2T-CHM13v2.04111,232,159 - 111,255,785 (+)NCBIT2T-CHM13v2.0
Cyp2u1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393131,084,140 - 131,097,806 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3131,082,090 - 131,096,876 (-)EnsemblGRCm39 Ensembl
GRCm383131,290,491 - 131,304,157 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3131,288,441 - 131,303,227 (-)EnsemblGRCm38mm10GRCm38
MGSCv373130,993,409 - 131,006,145 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363131,279,646 - 131,300,795 (-)NCBIMGSCv36mm8
Celera3137,811,630 - 137,824,364 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map360.89NCBI
LOC102028874
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554961,875,401 - 1,882,542 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554961,873,031 - 1,887,840 (-)NCBIChiLan1.0ChiLan1.0
CYP2U1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23106,029,669 - 106,052,193 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14106,324,613 - 106,347,107 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04100,436,365 - 100,458,845 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14111,009,198 - 111,031,269 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4111,009,198 - 111,031,269 (+)Ensemblpanpan1.1panPan2
CYP2U1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13228,426,250 - 28,445,399 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3228,438,173 - 28,444,383 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3213,576,376 - 13,596,209 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03228,655,415 - 28,674,792 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13228,648,718 - 28,668,053 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03228,393,226 - 28,412,584 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03211,444,133 - 11,463,495 (-)NCBIUU_Cfam_GSD_1.0
LOC101973126
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530112,681,300 - 12,703,056 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936818650,589 - 672,355 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936818650,593 - 672,349 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP2U1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8114,011,304 - 114,035,357 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18114,016,915 - 114,035,905 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28122,277,257 - 122,295,855 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CYP2U1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1755,859,669 - 55,880,266 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl755,859,849 - 55,879,280 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603734,484,923 - 34,506,814 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101708291
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248301,469,868 - 1,485,804 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248301,470,186 - 1,485,804 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cyp2u1
86 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:72
Count of miRNA genes:63
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000055570
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
2299161Iddm33Insulin dependent diabetes mellitus QTL 332.98blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2206312063220876787Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
1359019Hrtrt19Heart rate QTL 192.9heart pumping trait (VT:2000009)heart rate (CMO:0000002)2219753301226277316Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat

Markers in Region
RH128194  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22219,862,686 - 219,862,886 (+)MAPPERmRatBN7.2
Rnor_6.02236,427,410 - 236,427,609NCBIRnor6.0
Rnor_5.02254,976,344 - 254,976,543UniSTSRnor5.0
RGSC_v3.42228,784,465 - 228,784,664UniSTSRGSC3.4
RGSC_v3.4X114,406,191 - 114,406,389UniSTSRGSC3.4
Celera2212,118,709 - 212,118,908UniSTS
CeleraX91,534,121 - 91,534,319UniSTS
Cytogenetic MapXq33UniSTS
Cytogenetic Map2q43UniSTS
BE096408  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22219,853,715 - 219,853,874 (+)MAPPERmRatBN7.2
Rnor_6.02236,418,440 - 236,418,598NCBIRnor6.0
Rnor_5.02254,967,374 - 254,967,532UniSTSRnor5.0
RGSC_v3.42228,775,494 - 228,775,652UniSTSRGSC3.4
Celera2212,109,738 - 212,109,896UniSTS
RH 3.4 Map21549.4UniSTS
Cytogenetic Map2q43UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 2 11 3 19 3 17 22 30 11
Low 2 41 46 38 38 8 11 57 13 11 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000055570   ⟹   ENSRNOP00000052433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2219,849,407 - 219,866,882 (-)Ensembl
Rnor_6.0 Ensembl2236,414,135 - 236,431,596 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089674   ⟹   ENSRNOP00000069228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2219,853,912 - 219,866,882 (-)Ensembl
Rnor_6.0 Ensembl2236,415,918 - 236,431,683 (-)Ensembl
RefSeq Acc Id: NM_001393813   ⟹   NP_001380742
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82222,523,516 - 222,540,989 (-)NCBI
mRatBN7.22219,849,405 - 219,866,882 (-)NCBI
RefSeq Acc Id: NR_172016
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82222,523,516 - 222,540,989 (-)NCBI
mRatBN7.22219,849,405 - 219,866,882 (-)NCBI
RefSeq Acc Id: XM_039102449   ⟹   XP_038958377
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82222,523,516 - 222,541,055 (-)NCBI
mRatBN7.22219,849,403 - 219,866,959 (-)NCBI
RefSeq Acc Id: XM_063281955   ⟹   XP_063138025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82222,530,000 - 222,541,055 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000052433   ⟸   ENSRNOT00000055570
RefSeq Acc Id: ENSRNOP00000069228   ⟸   ENSRNOT00000089674
RefSeq Acc Id: XP_038958377   ⟸   XM_039102449
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001380742   ⟸   NM_001393813
- UniProtKB: Q4V8D1 (UniProtKB/Swiss-Prot),   A0A8L2UPN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138025   ⟸   XM_063281955
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4V8D1-F1-model_v2 AlphaFold Q4V8D1 1-530 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691759
Promoter ID:EPDNEW_R2284
Type:initiation region
Name:Cyp2u1_1
Description:cytochrome P450, family 2, subfamily u, polypeptide 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02236,431,589 - 236,431,649EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309433 AgrOrtholog
BioCyc Gene G2FUF-51208 BioCyc
Ensembl Genes ENSRNOG00000011053 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055010802 UniProtKB/Swiss-Prot
  ENSRNOG00060022963 UniProtKB/Swiss-Prot
  ENSRNOG00065014561 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000055570 ENTREZGENE
  ENSRNOT00000055570.4 UniProtKB/Swiss-Prot
  ENSRNOT00000089674.2 UniProtKB/TrEMBL
  ENSRNOT00055018264 UniProtKB/Swiss-Prot
  ENSRNOT00060039804 UniProtKB/Swiss-Prot
  ENSRNOT00065024060 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.630.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7456028 IMAGE-MGC_LOAD
InterPro Cyt_P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/Swiss-Prot
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:310848 UniProtKB/Swiss-Prot
MGC_CLONE MGC:114497 IMAGE-MGC_LOAD
NCBI Gene 310848 ENTREZGENE
PANTHER CYTOCHROME P450 2U1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CYTOCHROME P450 508A4-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam p450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cyp2u1 PhenoGen
PRINTS EP450I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P450 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011053 RatGTEx
  ENSRNOG00055010802 RatGTEx
  ENSRNOG00060022963 RatGTEx
  ENSRNOG00065014561 RatGTEx
Superfamily-SCOP SSF48264 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2UPN4 ENTREZGENE, UniProtKB/TrEMBL
  A6HVS8_RAT UniProtKB/TrEMBL
  CP2U1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Cyp2u1  cytochrome P450, family 2, subfamily u, polypeptide 1  Cyp2u1_predicted  cytochrome P450, family 2, subfamily u, polypeptide 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cyp2u1_predicted  cytochrome P450, family 2, subfamily u, polypeptide 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED