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Gene: Cyp2u1 (cytochrome P450, family 2, subfamily u, polypeptide 1) Mus musculus
Symbol: Cyp2u1
Name: cytochrome P450, family 2, subfamily u, polypeptide 1
Description: Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 56. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human CYP2U1 (cytochrome P450 family 2 subfamily U member 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; amiodarone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 8430436A10Rik; cytochrome P450 2U1; cytochrome P450, 2u1
Homo sapiens (human) : CYP2U1 (cytochrome P450 family 2 subfamily U member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cyp2u1 (cytochrome P450, family 2, subfamily u, polypeptide 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102028874 (cytochrome P450 2U1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100993565 (cytochrome P450 2U1)
Canis lupus familiaris (dog) : CYP2U1 (cytochrome P450 family 2 subfamily U member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101973126 (cytochrome P450 2U1)
Sus scrofa (pig) : LOC100518620 (cytochrome P450 2U1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm383131,290,491 - 131,304,157 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373130,993,409 - 131,006,145 (-)NCBIGRCm37mm9NCBIm37
MGSCv363131,279,646 - 131,300,795 (-)NCBImm8
Celera3137,811,630 - 137,824,364 (-)NCBICelera
Cytogenetic Map3 G3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cyp2u1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319775
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.