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Gene: Cyp2u1 (cytochrome P450, family 2, subfamily u, polypeptide 1) Mus musculus
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Symbol: Cyp2u1
Name: cytochrome P450, family 2, subfamily u, polypeptide 1
Description: Predicted to have heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Predicted to be involved in several processes, including exogenous drug catabolic process; organic acid metabolic process; and xenobiotic metabolic process. Predicted to localize to the cytoplasm and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 56. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human CYP2U1 (cytochrome P450 family 2 subfamily U member 1); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; amiodarone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 8430436A10Rik; cytochrome P450 2U1; cytochrome P450, 2u1
Orthologs:
Homo sapiens (human) : CYP2U1 (cytochrome P450 family 2 subfamily U member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cyp2u1 (cytochrome P450, family 2, subfamily u, polypeptide 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102028874 (cytochrome P450 2U1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100993565 (cytochrome P450 2U1)
Canis lupus familiaris (dog) : CYP2U1 (cytochrome P450 family 2 subfamily U member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101973126 (cytochrome P450 2U1)
Sus scrofa (pig) : LOC100518620 (cytochrome P450 2U1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm383131,290,491 - 131,304,157 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373130,993,409 - 131,006,145 (-)NCBIGRCm37mm9NCBIm37
MGSCv363131,279,646 - 131,300,795 (-)NCBImm8
Celera3137,811,630 - 137,824,364 (-)NCBICelera
Cytogenetic Map3 G3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cyp2u1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319775
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.