CYP2U1 (cytochrome P450 family 2 subfamily U member 1) - Rat Genome Database

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Gene: CYP2U1 (cytochrome P450 family 2 subfamily U member 1) Homo sapiens
Analyze
Symbol: CYP2U1
Name: cytochrome P450 family 2 subfamily U member 1
RGD ID: 1319774
HGNC Page HGNC:20582
Description: Enables arachidonate omega-hydroxylase activity. Involved in omega-hydroxylase P450 pathway. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Implicated in hereditary spastic paraplegia 56.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: cytochrome P450 2U1; cytochrome P450, family 2, subfamily U, polypeptide 1; long-chain fatty acid omega-monooxygenase; P450TEC; spastic paraplegia 49; spastic paraplegia 56 (autosomal dominant); SPG49; SPG56
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384107,931,549 - 107,953,461 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4107,931,549 - 107,953,461 (+)EnsemblGRCh38hg38GRCh38
GRCh374108,852,705 - 108,874,617 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364109,072,166 - 109,094,062 (+)NCBINCBI36Build 36hg18NCBI36
Build 344109,210,368 - 109,231,027NCBI
Celera4106,147,507 - 106,169,403 (+)NCBICelera
Cytogenetic Map4q25NCBI
HuRef4104,584,305 - 104,606,201 (+)NCBIHuRef
CHM1_14108,829,176 - 108,851,087 (+)NCBICHM1_1
T2T-CHM13v2.04111,232,159 - 111,255,785 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Original Reference(s)
CYP2U1Human3-Hydroxyacyl-CoA Dehydrogenase Deficiency  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Deficiency of 3-hydroxyacyl-CoA dehydrogenaseClinVarPMID:28492532
CYP2U1HumanDevelopmental Disabilities  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:23176821 more ...
CYP2U1Humanepilepsy  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: SeizureClinVar 
CYP2U1Humangenetic disease  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 and PMID:28492532
CYP2U1Humangenetic disease  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:28492532
CYP2U1Humangenetic disease  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVar 
CYP2U1Humangenetic disease  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:16783378 more ...
CYP2U1Humanhereditary spastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegiaClinVarPMID:25741868 more ...
CYP2U1Humanhereditary spastic paraplegia  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Hereditary spastic paraplegiaClinVarPMID:25741868 and PMID:28492532
CYP2U1Humanhereditary spastic paraplegia  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Hereditary spastic paraplegiaClinVarPMID:25741868
CYP2U1Humanhereditary spastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegiaClinVarPMID:14660610 more ...
CYP2U1Humanhereditary spastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegiaClinVarPMID:25741868 more ...
CYP2U1Humanhereditary spastic paraplegia 35  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: SPASTIC PARAPLEGIA 35 more ...ClinVarPMID:16783378 more ...
CYP2U1Humanhereditary spastic paraplegia 56  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 56ClinVarPMID:23176821 and PMID:25741868
CYP2U1Humanhereditary spastic paraplegia 56  IAGP (Homo sapiens) more ...8554872ClinVar more ...ClinVarPMID:25741868
CYP2U1Humanhereditary spastic paraplegia 56  IAGP (Homo sapiens) more ...8554872ClinVar more ...ClinVarPMID:25741868 and PMID:28492532
CYP2U1Humanhereditary spastic paraplegia 56  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 56ClinVarPMID:16783378 more ...
CYP2U1Humanhereditary spastic paraplegia 56  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 56ClinVarPMID:23176821 more ...
CYP2U1Humanhereditary spastic paraplegia 56  IAGP (Homo sapiens) and (Homo sapiens)8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 56ClinVarPMID:23176821
CYP2U1Humanhereditary spastic paraplegia 56  IAGP (Homo sapiens) more ...8554872ClinVar Annotator: match by term: Hereditary spastic paraplegia 56ClinVarPMID:33107650
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CYP2U1Humanautism spectrum disorder  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:35663546
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Original Reference(s)
CYP2U1Humanhereditary spastic paraplegia 56  IAGP 7240710 OMIM 

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Original Reference(s)
CYP2U1Human1,2-dichloroethane decreases expressionISOCyp2u1 (Mus musculus)6480464ethylene dichloride results in decreased expression of CYP2U1 mRNACTDPMID:28960355
CYP2U1Human1,2-dimethylhydrazine decreases expressionISOCyp2u1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of CYP2U1 mRNACTDPMID:22206623
CYP2U1Human17beta-estradiol increases expressionISOCyp2u1 (Mus musculus)6480464Estradiol results in increased expression of CYP2U1 mRNACTDPMID:39298647
CYP2U1Human17beta-hydroxy-5alpha-androstan-3-one increases expressionEXP 6480464Dihydrotestosterone results in increased expression of CYP2U1 mRNACTDPMID:29581250
CYP2U1Human2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOCyp2u1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with 2 more ...CTDPMID:28433925
CYP2U1Human2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOCyp2u1 (Mus musculus)64804642 more ...CTDPMID:38040069
CYP2U1Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCyp2u1 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in decreased expression of CYP2U1 mRNACTDPMID:21215274
CYP2U1Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISOCyp2u1 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in increased expression of CYP2U1 mRNACTDPMID:33387578
CYP2U1Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOCyp2u1 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with 2 more ...CTDPMID:28213091 and PMID:28433925
CYP2U1Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISOCyp2u1 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of CYP2U1 mRNACTDPMID:28922406
CYP2U1Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionISOCyp2u1 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of CYP2U1 mRNACTDPMID:28213091
CYP2U1Human2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of CYP2U1 mRNACTDPMID:20035023
CYP2U1Human4,4'-sulfonyldiphenol increases expressionISOCyp2u1 (Mus musculus)6480464bisphenol S results in increased expression of CYP2U1 mRNACTDPMID:39298647
CYP2U1Human6-propyl-2-thiouracil decreases expressionISOCyp2u1 (Rattus norvegicus)6480464Propylthiouracil results in decreased expression of CYP2U1 mRNACTDPMID:24780913
CYP2U1Humanaflatoxin B1 decreases methylationEXP 6480464Aflatoxin B1 results in decreased methylation of CYP2U1 geneCTDPMID:27153756
CYP2U1Humanall-trans-retinoic acid increases expressionEXP 6480464Tretinoin results in increased expression of CYP2U1 mRNACTDPMID:16985168
CYP2U1Humanall-trans-retinoic acid increases expressionISOCyp2u1 (Rattus norvegicus)6480464Tretinoin results in increased expression of CYP2U1 mRNACTDPMID:20488242
CYP2U1Humanamiodarone decreases expressionISOCyp2u1 (Mus musculus)6480464Amiodarone results in decreased expression of CYP2U1 mRNACTDPMID:24535564
CYP2U1Humanamitrole decreases expressionISOCyp2u1 (Rattus norvegicus)6480464Amitrole results in decreased expression of CYP2U1 mRNACTDPMID:38685447
CYP2U1Humanamphetamine decreases expressionISOCyp2u1 (Rattus norvegicus)6480464Amphetamine results in decreased expression of CYP2U1 mRNACTDPMID:30779732

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Biological Process

  
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Original Reference(s)
CYP2U1Humanarachidonate metabolic process involved_inIEAUniPathway:UPA00383150520179 UniProtGO_REF:0000041
CYP2U1Humancytochrome metabolic process involved_inTAS 150520179 ReactomeReactome:R-HSA-211958
CYP2U1Humanlipid metabolic process involved_inIEAUniProtKB-KW:KW-0443150520179 UniProtGO_REF:0000043
CYP2U1Humanomega-hydroxylase P450 pathway involved_inIDA 150520179 PMID:24563460UniProtPMID:24563460
CYP2U1Humanomega-hydroxylase P450 pathway involved_inTAS 150520179 ReactomeReactome:R-HSA-2142816
CYP2U1Humanorganic acid metabolic process involved_inIBAMGI:103238 more ...150520179 GO_CentralGO_REF:0000033
CYP2U1Humanxenobiotic metabolic process involved_inIBAPANTHER:PTN000670347 more ...150520179 GO_CentralGO_REF:0000033

Cellular Component
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Original Reference(s)
CYP2U1Humancytoplasm is_active_inIBAFB:FBgn0004959 more ...150520179 GO_CentralGO_REF:0000033
CYP2U1Humanendoplasmic reticulum located_inIEAUniProtKB-KW:KW-0256150520179 UniProtGO_REF:0000043
CYP2U1Humanendoplasmic reticulum membrane located_inTAS 150520179 ReactomeReactome:R-HSA-211960 more ...
CYP2U1Humanendoplasmic reticulum membrane located_inIEAUniProtKB-SubCell:SL-0097150520179 UniProtGO_REF:0000044
CYP2U1Humanintracellular membrane-bounded organelle located_inIEAUniProtKB-KW:KW-0492150520179 UniProtGO_REF:0000043
CYP2U1Humanintracellular membrane-bounded organelle is_active_inIBAFB:FBgn0004959 more ...150520179 GO_CentralGO_REF:0000033
CYP2U1Humanmembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
CYP2U1Humanmembrane located_inIEAUniProtKB-SubCell:SL-0162150520179 UniProtGO_REF:0000044
CYP2U1Humanmitochondrial inner membrane located_inIEAUniProtKB-SubCell:SL-0168150520179 UniProtGO_REF:0000044
CYP2U1Humanmitochondrial inner membrane located_inIEAUniProtKB-KW:KW-0999150520179 UniProtGO_REF:0000043
CYP2U1Humanmitochondrion located_inIEAUniProtKB-KW:KW-0496150520179 UniProtGO_REF:0000043
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Molecular Function
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Original Reference(s)
CYP2U1Humanarachidonate omega-hydroxylase activity enablesIDA 150520179 PMID:24563460UniProtPMID:24563460
CYP2U1Humanarachidonate omega-hydroxylase activity enablesIEARHEA:39755150520179 RHEAGO_REF:0000116
CYP2U1Humanheme binding enablesIEAUniRule:UR001528763150520179 UniProtGO_REF:0000104
CYP2U1Humanheme binding enablesIBAPANTHER:PTN000670347 more ...150520179 GO_CentralGO_REF:0000033
CYP2U1Humanheme binding enablesIEAInterPro:IPR001128 more ...150520179 InterProGO_REF:0000002
CYP2U1Humaniron ion binding enablesIEAInterPro:IPR001128 more ...150520179 InterProGO_REF:0000002
CYP2U1Humaniron ion binding enablesIEAUniRule:UR001528763150520179 UniProtGO_REF:0000104
CYP2U1Humanlong-chain fatty acid omega-hydroxylase activity enablesIEAEC:1.14.14.80150520179 UniProtGO_REF:0000003
CYP2U1Humanlong-chain fatty acid omega-hydroxylase activity enablesIEARHEA:56748150520179 RHEAGO_REF:0000116
CYP2U1Humanmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
CYP2U1Humanmonooxygenase activity enablesIEAARBA:ARBA00028788150520179 UniProtGO_REF:0000117
CYP2U1Humanmonooxygenase activity enablesIEAInterPro:IPR001128 more ...150520179 InterProGO_REF:0000002
CYP2U1Humanmonooxygenase activity enablesTAS 150520179 ReactomeReactome:R-HSA-211960 more ...
CYP2U1Humanmonooxygenase activity enablesIEAUniProtKB-KW:KW-0503150520179 UniProtGO_REF:0000043
CYP2U1Humanoxidoreductase activity enablesIEAUniProtKB-KW:KW-0560150520179 UniProtGO_REF:0000043
CYP2U1Humanoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen enablesIEAInterPro:IPR001128 more ...150520179 InterProGO_REF:0000002
CYP2U1Humanoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen enablesIBAPANTHER:PTN000670347 more ...150520179 GO_CentralGO_REF:0000033
CYP2U1Humanoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen enablesIEAInterPro:IPR008069150520179 InterProGO_REF:0000002
CYP2U1Humansteroid hydroxylase activity enablesIBAFB:FBgn0004959 more ...150520179 GO_CentralGO_REF:0000033
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Imported Annotations - SMPDB

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Original Reference(s)
CYP2U1Humanacetylsalicylic acid pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00083
CYP2U1Humanantipyrine drug pathway  EXP 10402751 SMPDBSMP:00692
CYP2U1Humanarachidonic acid metabolic pathway  EXP 10402751 SMPDBSMP:00075
CYP2U1Humancelecoxib pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00096
CYP2U1Humandiclofenac pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00093
CYP2U1Humandiflunisal pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00289
CYP2U1Humanetodolac pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00084
CYP2U1Humanfenoprofen pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00696
CYP2U1Humanflurbiprofen pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00697
CYP2U1Humanibuprofen pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00086
CYP2U1Humanindometacin pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00104
CYP2U1Humanindometacin pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00104
CYP2U1Humanketoprofen pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00085
CYP2U1Humanketorolac pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00098
CYP2U1Humanleukotriene C4 synthase deficiency pathway  EXP 10402751 SMPDBSMP:00353
CYP2U1Humanlornoxicam pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00700
CYP2U1Humanmagnesium salicylate pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00698
CYP2U1Humanmefenamic acid pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00109
CYP2U1Humanmeloxicam pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00106
CYP2U1Humannabumetone pharmacodynamics pathway  EXP 10402751 SMPDBSMP:00114
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Imported Annotations - KEGG (archival)

Object Symbol
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Original Reference(s)
CYP2U1Humanarachidonic acid metabolic pathway  IEA 6907045 KEGGhsa:00590
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Object Symbol
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Original Reference(s)
CYP2U1HumanAbnormal cerebral white matter morphology  IAGP 8699517 HPOMIM:615030
CYP2U1HumanAbnormal cerebral white matter morphology  IAGP 8699517 HPOORPHA:320411
CYP2U1HumanAbnormal globus pallidus morphology  IAGP 8699517 HPOORPHA:320411
CYP2U1HumanAutosomal recessive inheritance  IAGP 8699517 HPOMIM:615030
CYP2U1HumanBabinski sign  IAGP 8699517 HPOMIM:615030
CYP2U1HumanBabinski sign  IAGP 8699517 HPOORPHA:320411
CYP2U1HumanBasal ganglia calcification  IAGP 8699517 HPOMIM:615030
CYP2U1HumanChildhood onset  IAGP 8699517 HPOMIM:615030
CYP2U1HumanCognitive impairment  IAGP 8699517 HPOMIM:615030
CYP2U1HumanCognitive impairment  IAGP 8699517 HPOORPHA:320411
CYP2U1HumanCongenital onset  IAGP 8699517 HPOMIM:615030
CYP2U1HumanDelayed ability to walk  IAGP 8699517 HPOMIM:615030
CYP2U1HumanDystonia  IAGP 8699517 HPOMIM:615030
CYP2U1HumanDystonia  IAGP 8699517 HPOORPHA:320411
CYP2U1HumanGlobal developmental delay  IAGP 8699517 HPOORPHA:320411
CYP2U1HumanHypoplasia of the corpus callosum  IAGP 8699517 HPOMIM:615030
CYP2U1HumanHypoplasia of the corpus callosum  IAGP 8699517 HPOORPHA:320411
CYP2U1HumanInfantile onset  IAGP 8699517 HPOMIM:615030
CYP2U1HumanIntellectual disability  IAGP 8699517 HPOORPHA:320411
CYP2U1HumanIntellectual disability  IAGP 8699517 HPOMIM:615030
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Original Reference(s)
CYP2U1HumanAbnormality of the nervous system  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Abnormality of the nervous systemClinVarPMID:25741868
CYP2U1HumanGlobal developmental delay  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Global developmental delayClinVarPMID:23176821 more ...
CYP2U1HumanNeurodegeneration  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodegenerative diseaseClinVarPMID:23176821 more ...
CYP2U1HumanSeizure  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: SeizuresClinVar 
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:25741868 and PMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:23176821 more ...
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:23176821 more ...
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:23176821 more ...
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:23176821 more ...
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
CYP2U1HumanSpastic paraplegia  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:28492532
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#
Reference Title
Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. RGD HPO Phenotype Annotation Pipeline RGD automated import pipeline for human HPO-to-gene-to-disease annotations
PMID:12107412   PMID:12477932   PMID:14660610   PMID:14975754   PMID:15128046   PMID:15588491   PMID:20301682   PMID:20332099   PMID:20630735   PMID:21707071   PMID:21873635   PMID:24337409  
PMID:24563460   PMID:25857771   PMID:25872594   PMID:26914923   PMID:27292318   PMID:27456766   PMID:27553021   PMID:28083596   PMID:28725025   PMID:28743672   PMID:29034544   PMID:31281085  
PMID:32006740   PMID:32457219   PMID:33961781   PMID:34546337   PMID:36166872   PMID:36498943   PMID:36897256   PMID:38113892  



CYP2U1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384107,931,549 - 107,953,461 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4107,931,549 - 107,953,461 (+)EnsemblGRCh38hg38GRCh38
GRCh374108,852,705 - 108,874,617 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364109,072,166 - 109,094,062 (+)NCBINCBI36Build 36hg18NCBI36
Build 344109,210,368 - 109,231,027NCBI
Celera4106,147,507 - 106,169,403 (+)NCBICelera
Cytogenetic Map4q25NCBI
HuRef4104,584,305 - 104,606,201 (+)NCBIHuRef
CHM1_14108,829,176 - 108,851,087 (+)NCBICHM1_1
T2T-CHM13v2.04111,232,159 - 111,255,785 (+)NCBIT2T-CHM13v2.0
Cyp2u1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393131,084,140 - 131,097,806 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3131,082,090 - 131,096,876 (-)EnsemblGRCm39 Ensembl
GRCm383131,290,491 - 131,304,157 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3131,288,441 - 131,303,227 (-)EnsemblGRCm38mm10GRCm38
MGSCv373130,993,409 - 131,006,145 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363131,279,646 - 131,300,795 (-)NCBIMGSCv36mm8
Celera3137,811,630 - 137,824,364 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map360.89NCBI
Cyp2u1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82222,523,516 - 222,541,055 (-)NCBIGRCr8
mRatBN7.22219,849,403 - 219,866,959 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2219,849,407 - 219,866,882 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2227,505,747 - 227,523,224 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02225,405,415 - 225,422,891 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02220,263,041 - 220,280,518 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02236,414,131 - 236,431,650 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2236,414,135 - 236,431,683 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02254,963,065 - 254,980,117 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42228,771,187 - 228,788,636 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12228,757,928 - 228,775,376 (-)NCBI
Celera2212,105,431 - 212,122,977 (-)NCBICelera
Cytogenetic Map2q43NCBI
LOC102028874
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554961,875,401 - 1,882,542 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554961,873,031 - 1,887,840 (-)NCBIChiLan1.0ChiLan1.0
CYP2U1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23106,029,669 - 106,052,193 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14106,324,613 - 106,347,107 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04100,436,365 - 100,458,845 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14111,009,198 - 111,031,269 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4111,009,198 - 111,031,269 (+)Ensemblpanpan1.1panPan2
CYP2U1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13228,426,250 - 28,445,399 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3228,438,173 - 28,444,383 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3213,576,376 - 13,596,209 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03228,655,415 - 28,674,792 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13228,648,718 - 28,668,053 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03228,393,226 - 28,412,584 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03211,444,133 - 11,463,495 (-)NCBIUU_Cfam_GSD_1.0
LOC101973126
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530112,681,300 - 12,703,056 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936818650,589 - 672,355 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936818650,593 - 672,349 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP2U1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8114,011,304 - 114,035,357 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18114,016,915 - 114,035,905 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28122,277,257 - 122,295,855 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CYP2U1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1755,859,669 - 55,880,266 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl755,859,849 - 55,879,280 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603734,484,923 - 34,506,814 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101708291
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248301,469,868 - 1,485,804 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248301,470,186 - 1,485,804 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in CYP2U1
297 total Variants

1 to 10 of 333 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
NM_183075.3(CYP2U1):c.947A>T (p.Asp316Val) single nucleotide variant CYP2U1-related disorder [RCV004751232]|Global developmental delay [RCV000162142]|Hereditary spastic paraplegia 56 [RCV000032696]|Spastic paraplegia [RCV000162185]|not provided [RCV000442087] Chr4:107945426 [GRCh38]
Chr4:108866582 [GRCh37]
Chr4:4q25		 pathogenic|likely pathogenic
NM_183075.3(CYP2U1):c.1139A>G (p.Glu380Gly) single nucleotide variant Hereditary spastic paraplegia 56 [RCV000032697] Chr4:107947388 [GRCh38]
Chr4:108868544 [GRCh37]
Chr4:4q25		 pathogenic
NM_183075.3(CYP2U1):c.61_73del (p.Leu21fs) deletion Hereditary spastic paraplegia 56 [RCV000032698] Chr4:107931697..107931709 [GRCh38]
Chr4:108852853..108852865 [GRCh37]
Chr4:4q25		 pathogenic
NM_183075.3(CYP2U1):c.784T>C (p.Cys262Arg) single nucleotide variant Hereditary spastic paraplegia 56 [RCV000032699] Chr4:107945263 [GRCh38]
Chr4:108866419 [GRCh37]
Chr4:4q25		 pathogenic|likely pathogenic
NM_183075.3(CYP2U1):c.1462C>T (p.Arg488Trp) single nucleotide variant Hereditary spastic paraplegia 56 [RCV000032700]|Hereditary spastic paraplegia [RCV001847627]|Spastic paraplegia [RCV000814689]|not provided [RCV002264909] Chr4:107950250 [GRCh38]
Chr4:108871406 [GRCh37]
Chr4:4q25		 pathogenic|likely pathogenic|uncertain significance
NM_183075.3(CYP2U1):c.358T>C (p.Phe120Leu) single nucleotide variant Inborn genetic diseases [RCV002528284]|Spastic paraplegia [RCV001858042]|not provided [RCV000521418] Chr4:107932001 [GRCh38]
Chr4:108853157 [GRCh37]
Chr4:4q25		 uncertain significance
GRCh38/hg38 4q22.2-32.3(chr4:92913386-165299707)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051775]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051775]|See cases [RCV000051775] Chr4:92913386..165299707 [GRCh38]
Chr4:93834537..166220859 [GRCh37]
Chr4:94053560..166440309 [NCBI36]
Chr4:4q22.2-32.3		 pathogenic
GRCh38/hg38 4q22.3-28.3(chr4:96092893-136410207)x3 copy number gain See cases [RCV000051776] Chr4:96092893..136410207 [GRCh38]
Chr4:97014044..137331362 [GRCh37]
Chr4:97233067..137550812 [NCBI36]
Chr4:4q22.3-28.3		 pathogenic
GRCh38/hg38 4q24-25(chr4:105778347-110206873)x3 copy number gain See cases [RCV000051777] Chr4:105778347..110206873 [GRCh38]
Chr4:106699504..111128029 [GRCh37]
Chr4:106918953..111347478 [NCBI36]
Chr4:4q24-25		 pathogenic
NM_183075.3(CYP2U1):c.235C>G (p.Pro79Ala) single nucleotide variant Inborn genetic diseases [RCV004978278]|Spastic paraplegia [RCV001303163] Chr4:107931878 [GRCh38]
Chr4:108853034 [GRCh37]
Chr4:4q25		 uncertain significance
1 to 10 of 333 rows

Predicted Target Of
Summary Value
Count of predictions:1649
Count of miRNA genes:767
Interacting mature miRNAs:876
Transcripts:ENST00000332884, ENST00000508453, ENST00000513302
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1643256BW127_HBody Weight QTL 127 (human)1.310.007Body weightbody mass index4106319694132319694Human
597228679GWAS1324753_Happendicular lean mass QTL GWAS1324753 (human)3e-11appendicular lean mass4107939926107939927Human

SHGC-59281  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374108,873,767 - 108,873,891UniSTSGRCh37
Build 364109,093,216 - 109,093,340RGDNCBI36
Celera4106,168,557 - 106,168,681RGD
Cytogenetic Map4q25UniSTS
HuRef4104,605,355 - 104,605,479UniSTS
GeneMap99-GB4 RH Map4506.54UniSTS
Whitehead-RH Map4550.4UniSTS
A006Y35  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374108,873,492 - 108,873,675UniSTSGRCh37
Build 364109,092,941 - 109,093,124RGDNCBI36
Celera4106,168,282 - 106,168,465RGD
Cytogenetic Map4q25UniSTS
HuRef4104,605,080 - 104,605,263UniSTS
GeneMap99-GB4 RH Map4505.33UniSTS
D4S3152  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374108,873,798 - 108,873,891UniSTSGRCh37
Build 364109,093,247 - 109,093,340RGDNCBI36
Celera4106,168,588 - 106,168,681RGD
Cytogenetic Map4q25UniSTS
HuRef4104,605,386 - 104,605,479UniSTS
GeneMap99-G3 RH Map46162.0UniSTS
SHGC-50164  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374108,873,737 - 108,873,842UniSTSGRCh37
Build 364109,093,186 - 109,093,291RGDNCBI36
Celera4106,168,527 - 106,168,632RGD
Cytogenetic Map4q25UniSTS
HuRef4104,605,325 - 104,605,430UniSTS
TNG Radiation Hybrid Map466317.0UniSTS
SHGC-59620  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374108,874,332 - 108,874,459UniSTSGRCh37
Build 364109,093,781 - 109,093,908RGDNCBI36
Celera4106,169,122 - 106,169,249RGD
Cytogenetic Map4q25UniSTS
HuRef4104,605,920 - 104,606,047UniSTS
GeneMap99-GB4 RH Map4507.06UniSTS
NCBI RH Map41177.4UniSTS
SHGC-18776  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374108,865,290 - 108,865,379UniSTSGRCh37
Build 364109,084,739 - 109,084,828RGDNCBI36
Celera4106,160,080 - 106,160,169RGD
Cytogenetic Map4q25UniSTS
HuRef4104,596,878 - 104,596,967UniSTS
TNG Radiation Hybrid Map466317.0UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2435 2788 2252 4973 1724 2347 6 623 1932 464 2269 7287 6454 51 3734 1 852 1743 1614 174 1


1 to 24 of 24 rows
RefSeq Transcripts NG_007961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_183075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005262717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005262720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054348846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054348847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC114733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK026498 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY343323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC132767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC136483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU838483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX354124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX437421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD672608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 24 of 24 rows

Ensembl Acc Id: ENST00000332884   ⟹   ENSP00000333212
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4107,931,549 - 107,953,461 (+)Ensembl
Ensembl Acc Id: ENST00000508453   ⟹   ENSP00000423667
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4107,931,596 - 107,951,667 (+)Ensembl
Ensembl Acc Id: ENST00000513302
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl4107,931,585 - 107,936,607 (+)Ensembl
RefSeq Acc Id: NM_183075   ⟹   NP_898898
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384107,931,549 - 107,953,461 (+)NCBI
GRCh374108,852,716 - 108,874,617 (+)NCBI
Build 364109,072,166 - 109,094,062 (+)NCBI Archive
Celera4106,147,507 - 106,169,403 (+)RGD
HuRef4104,584,305 - 104,606,201 (+)RGD
CHM1_14108,829,176 - 108,851,087 (+)NCBI
T2T-CHM13v2.04111,233,835 - 111,255,785 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005262717   ⟹   XP_005262774
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384107,931,549 - 107,953,461 (+)NCBI
GRCh374108,852,716 - 108,874,617 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005262720   ⟹   XP_005262777
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh384107,931,549 - 107,953,461 (+)NCBI
GRCh374108,852,716 - 108,874,617 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054348846   ⟹   XP_054204821
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.04111,232,159 - 111,255,785 (+)NCBI
RefSeq Acc Id: XM_054348847   ⟹   XP_054204822
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.04111,233,835 - 111,255,785 (+)NCBI
RefSeq Acc Id: NP_898898   ⟸   NM_183075
- UniProtKB: B2RMV7 (UniProtKB/Swiss-Prot),   Q96EQ6 (UniProtKB/Swiss-Prot),   Q7Z449 (UniProtKB/Swiss-Prot),   A8K1T7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005262774   ⟸   XM_005262717
- Peptide Label: isoform X1
- UniProtKB: A8K1T7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005262777   ⟸   XM_005262720
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSP00000333212   ⟸   ENST00000332884
Ensembl Acc Id: ENSP00000423667   ⟸   ENST00000508453

Name Modeler Protein Id AA Range Protein Structure
AF-Q7Z449-F1-model_v2 AlphaFold Q7Z449 1-544 view protein structure

RGD ID:6868234
Promoter ID:EPDNEW_H7282
Type:initiation region
Name:CYP2U1_1
Description:cytochrome P450 family 2 subfamily U member 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh384107,931,549 - 107,931,609EPDNEW
RGD ID:6802149
Promoter ID:HG_KWN:48875
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid
Transcripts:NM_183075
Position:
Human AssemblyChrPosition (strand)Source
Build 364109,072,066 - 109,072,737 (+)MPROMDB


1 to 34 of 34 rows
Database
Acc Id
Source(s)
COSMIC CYP2U1 COSMIC
Ensembl Genes ENSG00000155016 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000332884 ENTREZGENE
  ENST00000332884.11 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.630.10 UniProtKB/Swiss-Prot
GTEx ENSG00000155016 GTEx
HGNC ID HGNC:20582 ENTREZGENE
Human Proteome Map CYP2U1 Human Proteome Map
InterPro Cyt_P450 UniProtKB/Swiss-Prot
  Cyt_P450_CS UniProtKB/Swiss-Prot
  Cyt_P450_E_grp-I UniProtKB/Swiss-Prot
  Cyt_P450_E_grp-I_CYP2D-like UniProtKB/Swiss-Prot
  Cyt_P450_sf UniProtKB/Swiss-Prot
  Cytochrome_P450_fam2 UniProtKB/Swiss-Prot
KEGG Report hsa:113612 UniProtKB/Swiss-Prot
NCBI Gene 113612 ENTREZGENE
OMIM 610670 OMIM
PANTHER CYTOCHROME P450 2U1 UniProtKB/Swiss-Prot
  CYTOCHROME P450 508A4-RELATED UniProtKB/Swiss-Prot
Pfam p450 UniProtKB/Swiss-Prot
PharmGKB PA134924269 PharmGKB
PRINTS EP450I UniProtKB/Swiss-Prot
  EP450ICYP2D UniProtKB/Swiss-Prot
  P450 UniProtKB/Swiss-Prot
PROSITE CYTOCHROME_P450 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48264 UniProtKB/Swiss-Prot
UniProt A8K1T7 ENTREZGENE, UniProtKB/TrEMBL
  B2RMV7 ENTREZGENE
  CP2U1_HUMAN UniProtKB/Swiss-Prot
  E9PGH5_HUMAN UniProtKB/TrEMBL
  Q7Z449 ENTREZGENE
  Q96EQ6 ENTREZGENE
UniProt Secondary B2RMV7 UniProtKB/Swiss-Prot
  Q96EQ6 UniProtKB/Swiss-Prot
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-15 CYP2U1  cytochrome P450 family 2 subfamily U member 1  CYP2U1  cytochrome P450, family 2, subfamily U, polypeptide 1  Symbol and/or name change 5135510 APPROVED