Phka1 (phosphorylase kinase regulatory subunit alpha 1) - Rat Genome Database

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Gene: Phka1 (phosphorylase kinase regulatory subunit alpha 1) Rattus norvegicus
Analyze
Symbol: Phka1
Name: phosphorylase kinase regulatory subunit alpha 1
RGD ID: 621522
Description: Predicted to enable choline-phosphate cytidylyltransferase activity. Predicted to be involved in positive regulation of glycogen catabolic process. Part of phosphorylase kinase complex. Used to study hypothyroidism. Human ortholog(s) of this gene implicated in glycogen storage disease and glycogen storage disease IXd. Orthologous to human PHKA1 (phosphorylase kinase regulatory subunit alpha 1); PARTICIPATES IN glycogen degradation pathway; calcium/calcium-mediated signaling pathway; insulin signaling pathway; INTERACTS WITH (+)-schisandrin B; acrylamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Pcyt1b; PhK-alpha-subunit; phosphorylase B kinase alpha subunit; phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform; phosphorylase kinase alpha 1; phosphorylase kinase alpha M subunit; phosphorylase kinase alpha-subunit; phosphorylase kinase, alpha 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X71,639,701 - 71,778,465 (-)NCBIGRCr8
mRatBN7.2X67,601,302 - 67,738,504 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX67,601,302 - 67,738,455 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX69,084,656 - 69,221,526 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X72,584,887 - 72,721,763 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X70,146,037 - 70,282,911 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X72,377,020 - 72,515,385 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX72,377,021 - 72,515,366 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X73,218,886 - 73,356,004 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X90,553,527 - 90,692,073 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X90,626,959 - 90,765,506 (-)NCBI
CeleraX67,954,686 - 68,091,557 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phosphorylase kinase: the complexity of its regulation is reflected in the complexity of its structure. Brushia RJ and Walsh DA, Front Biosci. 1999 Sep 15;4:D618-41.
2. Muscle glycogenosis with low phosphorylase kinase activity: mutations in PHKA1, PHKG1 or six other candidate genes explain only a minority of cases. Burwinkel B, etal., Eur J Hum Genet. 2003 Jul;11(7):516-26.
3. The content of glycogen phosphorylase and glycogen in preparations of sarcoplasmic reticulum-glycogenolytic complex is enhanced in diabetic rat skeletal muscle. Garduno E, etal., Diabetologia. 2001 Oct;44(10):1238-46.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
6. Both acidic and basic amino acids in an amphitropic enzyme, CTP:phosphocholine cytidylyltransferase, dictate its selectivity for anionic membranes. Johnson JE, etal., J Biol Chem 2003 Jan 3;278(1):514-22.
7. Baculovirus-mediated overexpression of the phosphorylase b kinase holoenzyme and alpha gamma delta and gamma delta subcomplexes. Kumar P, etal., Biochemistry. 2004 Aug 10;43(31):10247-54.
8. Phosphorylase a formation in protein-glycogen particles isolated from fast-twitch muscle of euthyroid and hypothyroid rats. Leijendekker WJ, etal., Arch Biochem Biophys 1989 Oct;274(1):120-9.
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. GOA pipeline RGD automated data pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Rat skeletal muscle phosphorylase kinase: turnover and control of isozyme levels in culture. Salsgiver WJ and Lawrence JC Jr, Am J Physiol. 1986 Mar;250(3 Pt 1):C365-73.
Additional References at PubMed
PMID:1512265   PMID:3362857  


Genomics

Comparative Map Data
Phka1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X71,639,701 - 71,778,465 (-)NCBIGRCr8
mRatBN7.2X67,601,302 - 67,738,504 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX67,601,302 - 67,738,455 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX69,084,656 - 69,221,526 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X72,584,887 - 72,721,763 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X70,146,037 - 70,282,911 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X72,377,020 - 72,515,385 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX72,377,021 - 72,515,366 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X73,218,886 - 73,356,004 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X90,553,527 - 90,692,073 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X90,626,959 - 90,765,506 (-)NCBI
CeleraX67,954,686 - 68,091,557 (-)NCBICelera
Cytogenetic MapXq22NCBI
PHKA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X72,578,814 - 72,714,306 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX72,578,814 - 72,714,319 (-)EnsemblGRCh38hg38GRCh38
GRCh37X71,798,664 - 71,934,154 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X71,717,203 - 71,850,612 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X71,583,501 - 71,716,903NCBI
CeleraX72,141,887 - 72,277,747 (-)NCBICelera
Cytogenetic MapXq13.1NCBI
HuRefX65,553,170 - 65,688,660 (-)NCBIHuRef
CHM1_1X71,691,651 - 71,827,294 (-)NCBICHM1_1
T2T-CHM13v2.0X71,011,736 - 71,147,907 (-)NCBIT2T-CHM13v2.0
Phka1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X101,557,581 - 101,687,907 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX101,557,581 - 101,687,852 (-)EnsemblGRCm39 Ensembl
GRCm38X102,513,975 - 102,644,301 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX102,513,975 - 102,644,246 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X99,709,314 - 99,839,585 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X98,718,393 - 98,846,917 (-)NCBIMGSCv36mm8
CeleraX89,425,232 - 89,555,150 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX45.47NCBI
Phka1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547512,020,629 - 12,172,443 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547512,020,278 - 12,172,427 (-)NCBIChiLan1.0ChiLan1.0
PHKA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X72,255,291 - 72,386,081 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X72,258,746 - 72,389,672 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X61,816,613 - 61,949,179 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X71,900,762 - 72,033,055 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX71,900,762 - 72,033,055 (-)Ensemblpanpan1.1panPan2
PHKA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X56,579,538 - 56,758,293 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX56,581,435 - 56,757,905 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX47,405,712 - 47,585,405 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X57,633,970 - 57,778,843 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX57,633,970 - 57,778,287 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X55,549,695 - 55,732,132 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X56,945,562 - 57,125,410 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X56,794,558 - 56,974,936 (-)NCBIUU_Cfam_GSD_1.0
Phka1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X45,213,224 - 45,321,344 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367621,657,781 - 1,766,605 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367621,657,778 - 1,766,592 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHKA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX58,455,939 - 58,583,216 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X58,456,097 - 58,583,216 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X66,182,346 - 66,288,186 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PHKA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X62,397,726 - 62,528,695 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX62,397,739 - 62,528,708 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660654,273,916 - 4,405,596 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phka1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249032,857,378 - 3,068,534 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249032,859,252 - 3,068,516 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Phka1
285 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:75
Interacting mature miRNAs:78
Transcripts:ENSRNOT00000041138
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX41304447112935181Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat

Markers in Region
RH142784  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X67,733,046 - 67,733,167 (+)MAPPERmRatBN7.2
Rnor_6.0X72,509,921 - 72,510,041NCBIRnor6.0
Rnor_5.0X73,350,562 - 73,350,682UniSTSRnor5.0
RGSC_v3.4X90,686,937 - 90,687,057UniSTSRGSC3.4
CeleraX68,086,431 - 68,086,551UniSTS
Cytogenetic MapXq31UniSTS
AU022198  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2687,791,311 - 87,791,510 (+)MAPPERmRatBN7.2
mRatBN7.2X67,673,699 - 67,673,898 (+)MAPPERmRatBN7.2
Rnor_6.0X72,449,832 - 72,450,030NCBIRnor6.0
Rnor_6.0691,610,683 - 91,610,881NCBIRnor6.0
Rnor_5.06101,068,322 - 101,068,520UniSTSRnor5.0
Rnor_5.0X73,291,717 - 73,291,915UniSTSRnor5.0
RGSC_v3.4X90,625,288 - 90,625,486UniSTSRGSC3.4
RGSC_v3.4691,274,523 - 91,274,721UniSTSRGSC3.4
Celera686,288,663 - 86,288,861UniSTS
CeleraX68,027,084 - 68,027,282UniSTS
Cytogenetic MapXq31UniSTS
Cytogenetic Map6q24UniSTS
UniSTS:236937  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X67,672,892 - 67,673,043 (+)MAPPERmRatBN7.2
Rnor_6.0X72,449,025 - 72,449,175NCBIRnor6.0
Rnor_5.0X73,290,910 - 73,291,060UniSTSRnor5.0
RGSC_v3.4X90,624,481 - 90,624,631UniSTSRGSC3.4
CeleraX68,026,277 - 68,026,427UniSTS
Cytogenetic MapXq31UniSTS
Cytogenetic Map6q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000041138   ⟹   ENSRNOP00000046508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX67,601,302 - 67,738,455 (-)Ensembl
Rnor_6.0 EnsemblX72,379,037 - 72,515,144 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075929
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX67,601,302 - 67,738,455 (-)Ensembl
Rnor_6.0 EnsemblX72,416,426 - 72,515,366 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX72,509,687 - 72,510,085 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076725   ⟹   ENSRNOP00000068281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX67,601,302 - 67,738,455 (-)Ensembl
Rnor_6.0 EnsemblX72,378,867 - 72,515,320 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076850   ⟹   ENSRNOP00000068112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX67,601,302 - 67,738,455 (-)Ensembl
Rnor_6.0 EnsemblX72,377,021 - 72,515,057 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095814   ⟹   ENSRNOP00000089808
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX67,601,302 - 67,738,455 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112197   ⟹   ENSRNOP00000092240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX67,601,302 - 67,738,455 (-)Ensembl
RefSeq Acc Id: NM_022626   ⟹   NP_072148
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X71,641,246 - 71,778,121 (-)NCBI
mRatBN7.2X67,601,302 - 67,738,185 (-)NCBI
Rnor_6.0X72,378,434 - 72,515,057 (-)NCBI
Rnor_5.0X73,218,886 - 73,356,004 (-)NCBI
RGSC_v3.4X90,553,527 - 90,692,073 (-)RGD
CeleraX67,954,686 - 68,091,557 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006257102   ⟹   XP_006257164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X71,639,701 - 71,778,465 (-)NCBI
mRatBN7.2X67,601,935 - 67,738,504 (-)NCBI
Rnor_6.0X72,377,020 - 72,515,385 (-)NCBI
Rnor_5.0X73,218,886 - 73,356,004 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063280283   ⟹   XP_063136353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X71,639,701 - 71,778,458 (-)NCBI
RefSeq Acc Id: XM_063280284   ⟹   XP_063136354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X71,639,701 - 71,778,438 (-)NCBI
RefSeq Acc Id: XM_063280285   ⟹   XP_063136355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X71,639,701 - 71,778,438 (-)NCBI
RefSeq Acc Id: NP_072148   ⟸   NM_022626
- UniProtKB: Q9QZ77 (UniProtKB/Swiss-Prot),   Q64651 (UniProtKB/Swiss-Prot),   Q64650 (UniProtKB/Swiss-Prot),   Q64649 (UniProtKB/Swiss-Prot),   A0A096MJF7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257164   ⟸   XM_006257102
- Peptide Label: isoform X3
- UniProtKB: Q9QZ77 (UniProtKB/Swiss-Prot),   Q64651 (UniProtKB/Swiss-Prot),   Q64650 (UniProtKB/Swiss-Prot),   Q64649 (UniProtKB/Swiss-Prot),   A0A096MJV9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000046508   ⟸   ENSRNOT00000041138
Ensembl Acc Id: ENSRNOP00000068112   ⟸   ENSRNOT00000076850
Ensembl Acc Id: ENSRNOP00000068281   ⟸   ENSRNOT00000076725
Ensembl Acc Id: ENSRNOP00000092240   ⟸   ENSRNOT00000112197
Ensembl Acc Id: ENSRNOP00000089808   ⟸   ENSRNOT00000095814
RefSeq Acc Id: XP_063136353   ⟸   XM_063280283
- Peptide Label: isoform X1
- UniProtKB: F1LLZ7 (UniProtKB/TrEMBL),   A0A8I6A560 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136355   ⟸   XM_063280285
- Peptide Label: isoform X4
- UniProtKB: F1LLZ7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136354   ⟸   XM_063280284
- Peptide Label: isoform X2
- UniProtKB: F1LLZ7 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64649-F1-model_v2 AlphaFold Q64649 1-1242 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701888
Promoter ID:EPDNEW_R12409
Type:initiation region
Name:Phka1_1
Description:phosphorylase kinase regulatory subunit alpha 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X72,515,343 - 72,515,403EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621522 AgrOrtholog
BioCyc Gene G2FUF-2058 BioCyc
Ensembl Genes ENSRNOG00000003063 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041138.6 UniProtKB/TrEMBL
  ENSRNOT00000075929.2 UniProtKB/TrEMBL
  ENSRNOT00000076725.3 UniProtKB/TrEMBL
  ENSRNOT00000076850.3 UniProtKB/TrEMBL
  ENSRNOT00000095814.1 UniProtKB/TrEMBL
  ENSRNOT00000112197.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 6-hairpin_glycosidase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6hp_glycosidase-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GH15-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KPBA/B_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHK_A/B_su UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:64561 UniProtKB/TrEMBL
NCBI Gene 64561 ENTREZGENE
PANTHER PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA, SKELETAL MUSCLE ISOFORM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10749 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glyco_hydro_15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KPBB_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Phka1 PhenoGen
RatGTEx ENSRNOG00000003063 RatGTEx
Superfamily-SCOP SSF48208 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MJF7 ENTREZGENE, UniProtKB/TrEMBL
  A0A096MJV9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A560 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GHN6_RAT UniProtKB/TrEMBL
  A0A8I6GK35_RAT UniProtKB/TrEMBL
  A6IQF1_RAT UniProtKB/TrEMBL
  F1LLZ7 ENTREZGENE, UniProtKB/TrEMBL
  KPB1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q64650 ENTREZGENE
  Q64651 ENTREZGENE
  Q9QZ77 ENTREZGENE
UniProt Secondary Q64650 UniProtKB/Swiss-Prot
  Q64651 UniProtKB/Swiss-Prot
  Q9QZ77 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-05-18 Phka1  phosphorylase kinase regulatory subunit alpha 1  Phka1  phosphorylase kinase, alpha 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-02-25 Phka1  phosphorylase kinase, alpha 1  Phka1  phosphorylase kinase alpha 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Phka1  phosphorylase kinase alpha 1  Pcyt1b  phosphorylase B kinase alpha subunit  Symbol and Name updated 1299863 APPROVED
2002-08-07 Pcyt1b  phosphorylase B kinase alpha subunit      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation translocation to membranes in vivo increases as a function of anionic lipid content 724642