Mapkapk3 (MAPK activated protein kinase 3)

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Gene: Mapkapk3 (MAPK activated protein kinase 3) Rattus norvegicus

Analyze

Symbol:

Mapkapk3

Name:

MAPK activated protein kinase 3

RGD ID:

1304980

Description:

Predicted to enable calmodulin binding activity; mitogen-activated protein kinase binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including macropinocytosis; response to lipopolysaccharide; and toll-like receptor signaling pathway. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in patterned macular dystrophy 3. Orthologous to human MAPKAPK3 (MAPK activated protein kinase 3); PARTICIPATES IN p38 MAPK signaling pathway; mitogen activated protein kinase signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC315994; MAP kinase-activated protein kinase 3; MAPK-activated protein kinase 3; MAPKAP kinase 3; MAPKAP-K3; MAPKAPK-3; mitogen-activated protein kinase-activated protein kinase 3; MK-3

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	107,929,754 - 107,963,638 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	107,929,762 - 107,963,568 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	113,556,431 - 113,590,016 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	111,755,606 - 111,789,192 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	109,598,393 - 109,631,978 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	116,012,126 - 116,046,012 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,012,121 - 116,045,954 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	115,368,430 - 115,402,297 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	112,497,626 - 112,531,778 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	112,517,080 - 112,551,233 (-)	NCBI
Celera	8	107,239,457 - 107,273,298 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bacteremia (ISO)

developmental and epileptic encephalopathy (ISO)

early infantile epileptic encephalopathy (ISO)

genetic disease (ISO)

malaria (ISO)

patterned macular dystrophy (ISO)

patterned macular dystrophy 3 (ISO)

tuberculosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

4,4'-sulfonyldiphenol (ISO)

acetylsalicylic acid (ISO)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-pinene (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

atazanavir sulfate (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

C60 fullerene (EXP)

cadmium atom (ISO)

caffeine (ISO)

carbon nanotube (ISO)

chenodeoxycholic acid (ISO)

cisplatin (ISO)

clofibric acid (EXP)

copper atom (ISO)

copper(0) (ISO)

cycloheximide (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

deoxycholic acid (ISO)

diazinon (ISO)

dibutyl phthalate (EXP)

diclofenac (ISO)

endosulfan (EXP)

fenamidone (ISO)

flurbiprofen (ISO)

folic acid (ISO)

fulvestrant (ISO)

gentamycin (EXP)

glycochenodeoxycholic acid (ISO)

glycocholic acid (ISO)

glycodeoxycholic acid (ISO)

glyphosate (EXP)

ibuprofen (ISO)

indole-3-methanol (EXP)

inulin (ISO)

lipopolysaccharide (ISO)

methoxyacetic acid (EXP)

methylmercury chloride (ISO)

mitomycin C (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-acetyl-L-cysteine (EXP)

N-methyl-N-nitrosourea (ISO)

N-nitrosodiethylamine (EXP)

nefazodone (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorooctane-1-sulfonic acid (ISO)

potassium dichromate (ISO)

rotenone (EXP)

SB 203580 (ISO)

sodium arsenite (ISO)

sodium dichromate (ISO)

Soman (EXP)

tartrazine (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene (EXP)

urethane (ISO)

valproic acid (ISO)

vanadium atom (ISO)

vanadium(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

intracellular signal transduction (IBA)

macropinocytosis (ISO,ISS)

phosphorylation (IEA)

response to cytokine (IBA,ISO,ISS)

response to lipopolysaccharide (ISO,ISS)

toll-like receptor signaling pathway (IBA,ISO,ISS)

Cellular Component

cytoplasm (IBA)

nucleoplasm (IEA,ISO)

nucleus (IBA)

Molecular Function

ATP binding (IEA)

calcium-dependent protein serine/threonine kinase activity (IBA)

calmodulin binding (IBA)

calmodulin-dependent protein kinase activity (IBA)

mitogen-activated protein kinase binding (IBA)

protein binding (ISO)

protein kinase activity (IEA)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IEA,ISO,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

mitogen activated protein kinase signaling pathway (IEA)

p38 MAPK signaling pathway (ISO)

vascular endothelial growth factor signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	MAPKAP kinases - MKs - two's company, three's a crowd.	Gaestel M Nat Rev Mol Cell Biol. 2006 Feb;7(2):120-30.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7799959	PMID:8774846	PMID:12477932	PMID:15489334	PMID:15850461	PMID:17906627

Genomics

Comparative Map Data

Mapkapk3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	107,929,754 - 107,963,638 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	107,929,762 - 107,963,568 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	113,556,431 - 113,590,016 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	111,755,606 - 111,789,192 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	109,598,393 - 109,631,978 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	116,012,126 - 116,046,012 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	116,012,121 - 116,045,954 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	115,368,430 - 115,402,297 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	112,497,626 - 112,531,778 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	112,517,080 - 112,551,233 (-)	NCBI
Celera	8	107,239,457 - 107,273,298 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

MAPKAPK3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	50,611,520 - 50,649,291 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	50,611,520 - 50,649,291 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	50,649,308 - 50,686,722 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	50,629,605 - 50,661,723 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	50,629,604 - 50,661,723	NCBI
Celera	3	50,627,403 - 50,659,525 (+)	NCBI		Celera
Cytogenetic Map	3	p21.2	NCBI
HuRef	3	50,705,224 - 50,742,794 (+)	NCBI		HuRef
CHM1_1	3	50,601,533 - 50,638,951 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	50,641,158 - 50,679,247 (+)	NCBI		T2T-CHM13v2.0

Mapkapk3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	107,132,125 - 107,167,082 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	107,132,126 - 107,167,076 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	107,254,927 - 107,289,877 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	107,254,927 - 107,289,877 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	107,157,258 - 107,192,208 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	107,113,028 - 107,147,978 (-)	NCBI		MGSCv36	mm8
Celera	9	106,860,944 - 106,896,004 (-)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	57.98	NCBI

Mapkapk3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955532	2,392,539 - 2,420,604 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955532	2,392,539 - 2,419,219 (+)	NCBI	ChiLan1.0	ChiLan1.0

MAPKAPK3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	3	50,601,850 - 50,634,117 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	50,542,547 - 50,574,817 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	51,779,906 - 51,812,124 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	51,779,912 - 51,812,124 (+)	Ensembl	panpan1.1		panPan2

MAPKAPK3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	38,731,492 - 38,759,000 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	38,732,397 - 38,758,494 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	38,649,808 - 38,677,437 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	39,084,740 - 39,112,355 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	39,084,740 - 39,112,232 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	38,452,657 - 38,480,274 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	38,856,269 - 38,883,882 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	39,136,177 - 39,163,793 (-)	NCBI		UU_Cfam_GSD_1.0

Mapkapk3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	65,369,894 - 65,399,362 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	2,130,252 - 2,160,313 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936529	2,130,421 - 2,159,859 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAPKAPK3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	33,097,393 - 33,125,818 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	33,097,329 - 33,125,820 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	36,318,931 - 36,348,176 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAPKAPK3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	11,998,774 - 12,036,477 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666041	154,949,436 - 154,982,394 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mapkapk3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624730	4,446,850 - 4,476,630 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624730	4,446,815 - 4,492,753 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mapkapk3
104 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	401
Count of miRNA genes:	191
Interacting mature miRNAs:	232
Transcripts:	ENSRNOT00000020065
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	40952565	123900184	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	absolute change in systolic blood pressure (CMO:0000607)	8	46531639	119088626	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	46531639	119088626	Rat
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	61290298	119084929	Rat
631653	Bp125	Blood pressure QTL 125	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	66142385	111142385	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	69349194	112783834	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	70513503	118219066	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	71888757	116888757	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	71888757	116888757	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	71888757	116888757	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	71888757	116888757	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	73473045	118473045	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	76468691	121468691	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	82460758	122812818	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	89265192	114019816	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	93535351	123900184	Rat
1358893	Bp263	Blood pressure QTL 263	5.01		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
1358903	Bp252	Blood pressure QTL 252	7	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	93965141	123900184	Rat
738014	Anxrr15	Anxiety related response QTL 15	3.6	0.005	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	95718998	123900184	Rat
2300182	Bmd56	Bone mineral density QTL 56	5.4		femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	95718998	123900184	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	100149864	120994388	Rat
631217	Activ1	Activity QTL 1	15.9		voluntary movement trait (VT:0003491)	number of photobeam interruptions in an experimental apparatus (CMO:0001517)	8	102370617	108923645	Rat

Markers in Region

RH128348

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	107,929,828 - 107,930,012 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,012,201 - 116,012,384	NCBI	Rnor6.0
Rnor_5.0	8	115,368,502 - 115,368,685	UniSTS	Rnor5.0
RGSC_v3.4	8	112,497,693 - 112,497,876	UniSTS	RGSC3.4
Celera	8	107,239,524 - 107,239,707	UniSTS
RH 3.4 Map	8	1139.5	UniSTS
Cytogenetic Map	8	q32	UniSTS

AI874665

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	107,929,959 - 107,930,083 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	116,012,332 - 116,012,455	NCBI	Rnor6.0
Rnor_5.0	8	115,368,633 - 115,368,756	UniSTS	Rnor5.0
RGSC_v3.4	8	112,497,824 - 112,497,947	UniSTS	RGSC3.4
Celera	8	107,239,655 - 107,239,778	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	23	9	7	13	7	6	9	4	21	32	11	6
Low		20	48	34	6	34	2	2	70	14	9		2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001012127	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006243776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008766531	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC081974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000200	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000020065 ⟹ ENSRNOP00000020065

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	107,929,762 - 107,963,568 (-)	Ensembl
Rnor_6.0 Ensembl	8	116,012,121 - 116,045,954 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000094925 ⟹ ENSRNOP00000091496

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	107,929,762 - 107,963,568 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000100521 ⟹ ENSRNOP00000096910

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	107,929,762 - 107,963,568 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000114765 ⟹ ENSRNOP00000088134

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	107,929,762 - 107,939,239 (-)	Ensembl

RefSeq Acc Id:

NM_001012127 ⟹ NP_001012127

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	107,929,762 - 107,963,568 (-)	NCBI
Rnor_6.0	8	116,012,134 - 116,045,926 (-)	NCBI
Rnor_5.0	8	115,368,430 - 115,402,297 (-)	NCBI
RGSC_v3.4	8	112,497,626 - 112,531,778 (-)	RGD
Celera	8	107,239,457 - 107,273,298 (-)	RGD

Sequence:

show sequence

GACTCTGGGTCCAGGGCTCCCCTCCGCAGCGGACTCCAGGCCTCACTATCTCTTGCCCCTCTCG
CCTACAACATGACTTCCGTCTAGTGCTTTGCCATCAAGTGCGCCTTCGCCTGGCACGCCTTTCC
TGGGCCCCTATATGGCCGTTTCTCAAGACCTGGCTGCTTCACTGCGCCGGACTCCTCAACTCCA
CATGTGCCTGGGCTGAGGGATCACCTCCCCCTGCTGTACGTGCCTCTGGACGTGCCAGGCTGGG
GCTACCTACAAGCGCCCCGTGGGGGCCATGGATGGCGAGACGGCGGGGGAGAAGGGGAGTCTTG
TGCCCCAGCCAGGTGCGCTCGGTGCGCCCGCCTTGGGCGGTGCTCCGGCCCCAGGTGTGCGACG
GGAACCCAAGAAGTACGCGGTGACTGATGACTACCAGTTGTCCAAGCAAGTGCTGGGTCTGGGT
GTGAACGGCAAGGTACTAGAGTGCTACCATCGGCGCTCTGGGCAGAAGTGTGCCTTGAAGCTCC
TGTATGACAGCCCCAAGGCCCGGCAGGAGGTGGACCACCACTGGCAGGCCTCAGGCGGCCCCCA
CATTGTGCGCATCCTGGACGTGTACGAGAACATGCATCACGGCAAGCGCTGCCTCCTCATCGTC
ATGGAATGCATGGAGGGTGGTGAGCTGTTCAGCAGGATTCAGGAGCGCGGTGATCAGGCTTTCA
CTGAGAGAGAGGCCGCAGAGATAATGCGGGACATTGGCACTGCCATCCAGTTCTTGCACAGCCA
GAACATTGCCCACCGAGATGTCAAGCCTGAAAACCTACTCTATACATCCAAGGAGAAGGATGCT
GTACTTAAACTCACTGATTTTGGCTTTGCCAAGGAAACCACCCAAAATGCCCTCCAGACACCCT
GTTACACTCCCTATTATGTGGCTCCTGAGGTCCTGGGTCCAGAGAAGTATGACAAGTCGTGCGA
TATGTGGTCCCTGGGGGTCATCATGTACATCCTTTTGTGTGGATTCCCACCCTTCTACTCCAAC
ACGGGCCAGGCCATCTCTCCAGGAATGAAGAGAAGGATTCGCTTGGGCCAGTATGGCTTCCCTA
AACCTGAATGGGCAGACGTCTCTGAGGATGCCAAGCAGCTAATCCGTCTGCTCCTGAAGACAGA
TCCCACCGAGAGGCTGACCATCATGCAGTTTATGAACCATCCTTGGATCAATCAATCGATGGAG
GTCCCACAGACCCCACTCCATACAGCCCGAGTGCTGGAGGAAGACAAAGACCACTGGGATGACG
TCAAGGAAGAGATGACCAGTGCCCTGGCCACGATGAGGGTAGACTACGACCAGGTGAAAATCAA
GGACCTGAAGACCTCTAACAACCGACTCCTCAACAAGCGGAGGAAAAAGCAGGGGGGCAGCTCC
TCAGCCTCACCGGGATGCAACAACCAGTAACTCGTGGTGCCTTGGAGGAGCCAGACTGACAGAC
TCTAACGTCCTGAGGCTCTGGCCAGGAGGGGCTGGAGTCATTCTTAAAACAAAAGGAGAATTTT
GTTGTCTTAATGTGTCACATTGAACTTGAGGATAAAGAGCTTGGCCCAAGAGTCCCGGCCTAAG
TCTCAGGCTCTAGAAAGCTGTGGGTCCTCGGGGATGGGAGCTCTCTGCTACAGCTGAGGCAACT
TTGTACACTGGCTTGACTGAGGCCACAGCTCTGTTTTGCCTTAGGACATAGCCTTACTTCTAGG
CCACTGGGAGTTGTGGTGGATCTACCCTTTTTCTATAAAGGATGTATCCTGCTGTGTGGGCAGA
TGGGTCTGGCCTTGAGGAAAGTATTGGGCCATTGGTTGCTATGGTGACCAGAGGCCATGTTGCT
GTCTGAGAATACTGAACAAAGGCGGAAGGAGGGACAGTCAAGGGTCTACCTTCTTGGGGAGGTT
TGTCTCTCTCACACTGGCTGTCCTTCCCCAGGCTCACTCCTCTGTGGTCTGCCAGAGGCTACAG
AGTCCTGCTTGCTTATTTTCCTGGATGGTCCAGCCCTGGCTTACTATAGCATGAGCCCATGTAA
CACTCAGAGAGACACTAGGGTCCCTGGCACCAAGCATCCTGTCATTACCCCCTGATCTAAAAGG
TAACTTCTCATCTCAACTGGAGAACTTCCCTGTGACAAACGCTCCCATCTCTTCCTACTCACCA
GATCTCAGGTAGGAAAGCCTGTCTCTGCGGCTAGCACTGGCTACCCTTGGGTTTACTTTTGTGA
AAGGGAGTGCTTGGCTCCCTGTGACCCAGGACCTTTTCCTGTACTCTGGATCAGACCTGGGTGG
TGAAGAGCTGCTGAGCCACGCCTTCAAGGGGTCTGGTCCTGGCTGTAGCCTGAGTGGAGCAGAG
AGGGTTTTCCTTGGCGGAGCCCAGACTTAGCCAGCTCTGCCCTGTCCTGCGCAGGGTAACATCC
AGGTGCTGAGTGGTTGATTGGTGACCTAACAAGTGCCTGGCACCCAGTCTCCTTCCTAGATGAT
CCTAGATCCTGGCCTTTCTCACTGGCTGGGAAACCTTAGATCTTGTCAGCCACAACAGTGCTGC
TGGGTTTTATATTCAGATATTAATAAACACATTTTTAACGTTTTAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006243776 ⟹ XP_006243838

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	107,929,754 - 107,963,636 (-)	NCBI
Rnor_6.0	8	116,012,126 - 116,046,012 (-)	NCBI
Rnor_5.0	8	115,368,430 - 115,402,297 (-)	NCBI

Sequence:

show sequence

CCCTTTAAGGCTGACCTAGCGGGGCCCCAAGTCCAGATGACGCGCCCAGAAGGGGGATGGGGGG
TCACGTGGGGCGCGGACCGCGAGACTCTGGGTCCAGGGCTCCCCTCCGCAGCGGACTCCAGGCC
TCACTATCTCTTGCCCCTCTCGCCTACAACATGACTTCCGTCTAGTGCTTTGCCATCAAGTGCG
CCTTCGCCTGGCACGCCTTTCCTGGGCCCCTATATGGCCGTTTCTCAAGACCTGGCTGCTTCAC
TGCGCCGGACTCCTCAACTCCACATGTGCCTGGGCTGAGGGATCACCTCCCCCTGCTGTGCCTC
TGGACGTGCCAGGCTGGGGCTACCTACAAGCGCCCCGTGGGGGCCATGGATGGCGAGACGGCGG
GGGAGAAGGGGAGTCTTGTGCCCCAGCCAGGTGCGCTCGGTGCGCCCGCCTTGGGCGGTGCTCC
GGCCCCAGGTGTGCGACGGGAACCCAAGAAGTACGCGGTGACTGATGACTACCAGTTGTCCAAG
CAAGTGCTGGGTCTGGGTGTGAACGGCAAGGTACTAGAGTGCTACCATCGGCGCTCTGGGCAGA
AGTGTGCCTTGAAGCTCCTGTATGACAGCCCCAAGGCCCGGCAGGAGGTGGACCACCACTGGCA
GGCCTCAGGCGGCCCCCACATTGTGCGCATCCTGGACGTGTACGAGAACATGCATCACGGCAAG
CGCTGCCTCCTCATCGTCATGGAATGCATGGAGGGTGGTGAGCTGTTCAGCAGGATTCAGGAGC
GCGGTGATCAGGCTTTCACTGAGAGAGAGGCCGCAGAGATAATGCGGGACATTGGCACTGCCAT
CCAGTTCTTGCACAGCCAGAACATTGCCCACCGAGATGTCAAGCCTGAAAACCTACTCTATACA
TCCAAGGAGAAGGATGCTGTACTTAAACTCACTGATTTTGGCTTTGCCAAGGAAACCACCCAAA
ATGCCCTCCAGACACCCTGTTACACTCCCTATTATGTGGCTCCTGAGGTCCTGGGTCCAGAGAA
GTATGACAAGTCGTGCGATATGTGGTCCCTGGGGGTCATCATGTACATCCTTTTGTGTGGATTC
CCACCCTTCTACTCCAACACGGGCCAGGCCATCTCTCCAGGAATGAAGAGAAGGATTCGCTTGG
GCCAGTATGGCTTCCCTAAACCTGAATGGGCAGACGTCTCTGAGGATGCCAAGCAGCTAATCCG
TCTGCTCCTGAAGACAGATCCCACCGAGAGGCTGACCATCATGCAGTTTATGAACCATCCTTGG
ATCAATCAATCGATGGAGGTCCCACAGACCCCACTCCATACAGCCCGAGTGCTGGAGGAAGACA
AAGACCACTGGGATGACGTCAAGGAAGAGATGACCAGTGCCCTGGCCACGATGAGGGTAGACTA
CGACCAGGTGAAAATCAAGGACCTGAAGACCTCTAACAACCGACTCCTCAACAAGCGGAGGAAA
AAGCAGGGGGGCAGCTCCTCAGCCTCACCGGGATGCAACAACCAGTAACTCGTGGTGCCTTGGA
GGAGCCAGACTGACAGACTCTAACGTCCTGAGGCTCTGGCCAGGAGGGGCTGGAGTCATTCTTA
AAACAAAAGGAGAATTTTGTTGTCTTAATGTGTCACATTGAACTTGAGGATAAAGAGCTTGGCC
CAAGAGTCCCGGCCTAAGTCTCAGGCTCTAGAAAGCTGTGGGTCCTCGGGGATGGGAGCTCTCT
GCTACAGCTGAGGCAACTTTGTACACTGGCTTGACTGAGGCCACAGCTCTGTTTTGCCTTAGGA
CATAGCCTTACTTCTAGGCCACTGGGAGTTGTGGTGGATCTACCCTTTTTCTATAAAGGATGTA
TCCTGCTGTGTGGGCAGATGGGTCTGGCCTTGAGGAAAGTATTGGGCCATTGGTTGCTATGGTG
ACCAGAGGCCATGTTGCTGTCTGAGAATACTGAACAAAGGCGGAAGGAGGGACAGTCAAGGGTC
TACCTTCTTGGGGAGGTTTGTCTCTCTCACACTGGCTGTCCTTCCCCAGGCTCACTCCTCTGTG
GTCTGCCAGAGGCTACAGAGTCCTGCTTGCTTATTTTCCTGGATGGTCCAGCCCTGGCTTACTA
TAGCATGAGCCCATGTAACACTCAGAGAGACACTAGGGTCCCTGGCACCAAGCATCCTGTCATT
ACCCCCTGATCTAAAAGGTAACTTCTCATCTCAACTGGAGAACTTCCCTGTGACAAACGCTCCC
ATCTCTTCCTACTCACCAGATCTCAGGTAGGAAAGCCTGTCTCTGCGGCTAGCACTGGCTACCC
TTGGGTTTACTTTTGTGAAAGGGAGTGCTTGGCTCCCTGTGACCCAGGACCTTTTCCTGTACTC
TGGATCAGACCTGGGTGGTGAAGAGCTGCTGAGCCACGCCTTCAAGGGGTCTGGTCCTGGCTGT
AGCCTGAGTGGAGCAGAGAGGGTTTTCCTTGGCGGAGCCCAGACTTAGCCAGCTCTGCCCTGTC
CTGCGCAGGGTAACATCCAGGTGCTGAGTGGTTGATTGGTGACCTAACAAGTGCCTGGCACCCA
GTCTCCTTCCTAGATGATCCTAGATCCTGGCCTTTCTCACTGGCTGGGAAACCTTAGATCTTGT
CAGCCACAACAGTGCTGCTGGGTTTTATATTCAGATATTAATAAACACATTTTTAACGTTTTTT
CAATGA

hide sequence

RefSeq Acc Id:

XM_008766531 ⟹ XP_008764753

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	8	107,929,754 - 107,963,638 (-)	NCBI
Rnor_6.0	8	116,012,126 - 116,046,012 (-)	NCBI

Sequence:

show sequence

CCCTTTAAGGCTGACCTAGCGGGGCCCCAAGTCCAGATGACGCGCCCAGAAGGGGGATGGGGGG
TCACGTGGGGCGCGGACCGCGAGACTCTGGGTCCAGGGCTCCCCTCCGCAGCGGACTCCAGGCC
TCACTATCTCTTGCCCCTCTCGCCTACAACATGACTTCCGTCTAGTGCTTTGCCATCAAGTGCG
CCTTCGCCTGGCACGCCTTTCCTGGGCCCCTATATGGCCGTTTCTCAAGACCTGGCTGCTTCAC
TGCGCCGGACTCCTCAACTCCACATGTGCCTGGGCTGAGGGATCACCTCCCCCTGCTGTACGTA
GGTGCCTCTGGACGTGCCAGGCTGGGGCTACCTACAAGCGCCCCGTGGGGGCCATGGATGGCGA
GACGGCGGGGGAGAAGGGGAGTCTTGTGCCCCAGCCAGGTGCGCTCGGTGCGCCCGCCTTGGGC
GGTGCTCCGGCCCCAGGTGTGCGACGGGAACCCAAGAAGTACGCGGTGACTGATGACTACCAGT
TGTCCAAGCAAGTGCTGGGTCTGGGTGTGAACGGCAAGGTACTAGAGTGCTACCATCGGCGCTC
TGGGCAGAAGTGTGCCTTGAAGCTCCTGTATGACAGCCCCAAGGCCCGGCAGGAGGTGGACCAC
CACTGGCAGGCCTCAGGCGGCCCCCACATTGTGCGCATCCTGGACGTGTACGAGAACATGCATC
ACGGCAAGCGCTGCCTCCTCATCGTCATGGAATGCATGGAGGGTGGTGAGCTGTTCAGCAGGAT
TCAGGAGCGCGGTGATCAGGCTTTCACTGAGAGAGAGGCCGCAGAGATAATGCGGGACATTGGC
ACTGCCATCCAGTTCTTGCACAGCCAGAACATTGCCCACCGAGATGTCAAGCCTGAAAACCTAC
TCTATACATCCAAGGAGAAGGATGCTGTACTTAAACTCACTGATTTTGGCTTTGCCAAGGAAAC
CACCCAAAATGCCCTCCAGACACCCTGTTACACTCCCTATTATGTGGCTCCTGAGGTCCTGGGT
CCAGAGAAGTATGACAAGTCGTGCGATATGTGGTCCCTGGGGGTCATCATGTACATCCTTTTGT
GTGGATTCCCACCCTTCTACTCCAACACGGGCCAGGCCATCTCTCCAGGAATGAAGAGAAGGAT
TCGCTTGGGCCAGTATGGCTTCCCTAAACCTGAATGGGCAGACGTCTCTGAGGATGCCAAGCAG
CTAATCCGTCTGCTCCTGAAGACAGATCCCACCGAGAGGCTGACCATCATGCAGTTTATGAACC
ATCCTTGGATCAATCAATCGATGGAGGTCCCACAGACCCCACTCCATACAGCCCGAGTGCTGGA
GGAAGACAAAGACCACTGGGATGACGTCAAGGAAGAGATGACCAGTGCCCTGGCCACGATGAGG
GTAGACTACGACCAGGTGAAAATCAAGGACCTGAAGACCTCTAACAACCGACTCCTCAACAAGC
GGAGGAAAAAGCAGGGGGGCAGCTCCTCAGCCTCACCGGGATGCAACAACCAGTAACTCGTGGT
GCCTTGGAGGAGCCAGACTGACAGACTCTAACGTCCTGAGGCTCTGGCCAGGAGGGGCTGGAGT
CATTCTTAAAACAAAAGGAGAATTTTGTTGTCTTAATGTGTCACATTGAACTTGAGGATAAAGA
GCTTGGCCCAAGAGTCCCGGCCTAAGTCTCAGGCTCTAGAAAGCTGTGGGTCCTCGGGGATGGG
AGCTCTCTGCTACAGCTGAGGCAACTTTGTACACTGGCTTGACTGAGGCCACAGCTCTGTTTTG
CCTTAGGACATAGCCTTACTTCTAGGCCACTGGGAGTTGTGGTGGATCTACCCTTTTTCTATAA
AGGATGTATCCTGCTGTGTGGGCAGATGGGTCTGGCCTTGAGGAAAGTATTGGGCCATTGGTTG
CTATGGTGACCAGAGGCCATGTTGCTGTCTGAGAATACTGAACAAAGGCGGAAGGAGGGACAGT
CAAGGGTCTACCTTCTTGGGGAGGTTTGTCTCTCTCACACTGGCTGTCCTTCCCCAGGCTCACT
CCTCTGTGGTCTGCCAGAGGCTACAGAGTCCTGCTTGCTTATTTTCCTGGATGGTCCAGCCCTG
GCTTACTATAGCATGAGCCCATGTAACACTCAGAGAGACACTAGGGTCCCTGGCACCAAGCATC
CTGTCATTACCCCCTGATCTAAAAGGTAACTTCTCATCTCAACTGGAGAACTTCCCTGTGACAA
ACGCTCCCATCTCTTCCTACTCACCAGATCTCAGGTAGGAAAGCCTGTCTCTGCGGCTAGCACT
GGCTACCCTTGGGTTTACTTTTGTGAAAGGGAGTGCTTGGCTCCCTGTGACCCAGGACCTTTTC
CTGTACTCTGGATCAGACCTGGGTGGTGAAGAGCTGCTGAGCCACGCCTTCAAGGGGTCTGGTC
CTGGCTGTAGCCTGAGTGGAGCAGAGAGGGTTTTCCTTGGCGGAGCCCAGACTTAGCCAGCTCT
GCCCTGTCCTGCGCAGGGTAACATCCAGGTGCTGAGTGGTTGATTGGTGACCTAACAAGTGCCT
GGCACCCAGTCTCCTTCCTAGATGATCCTAGATCCTGGCCTTTCTCACTGGCTGGGAAACCTTA
GATCTTGTCAGCCACAACAGTGCTGCTGGGTTTTATATTCAGATATTAATAAACACATTTTTAA
CGTTTTTTCAATGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001012127	(Get FASTA)	NCBI Sequence Viewer
	XP_006243838	(Get FASTA)	NCBI Sequence Viewer
	XP_008764753	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH81974	(Get FASTA)	NCBI Sequence Viewer
	EDL77263	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000020065
	ENSRNOP00000088134.1
	ENSRNOP00000091496.1
	ENSRNOP00000096910.1
GenBank Protein	Q66H84	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001012127 ⟸ NM_001012127

- UniProtKB:

Q66H84 (UniProtKB/Swiss-Prot), A6I2W4 (UniProtKB/TrEMBL), A0A8I6AVR4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MDGETAGEKGSLVPQPGALGAPALGGAPAPGVRREPKKYAVTDDYQLSKQVLGLGVNGKVLECY
HRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGGEL
FSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSQNIAHRDVKPENLLYTSKEKDAVLKLTDFGF
AKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGM
KRRIRLGQYGFPKPEWADVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMEVPQTPLHTA
RVLEEDKDHWDDVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQGGSSSASPGCNNQ

hide sequence

RefSeq Acc Id:	XP_006243838 ⟸ XM_006243776
- Peptide Label:	isoform X1
- UniProtKB:	Q66H84 (UniProtKB/Swiss-Prot), A6I2W4 (UniProtKB/TrEMBL), A0A8I6AVR4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDGETAGEKGSLVPQPGALGAPALGGAPAPGVRREPKKYAVTDDYQLSKQVLGLGVNGKVLECY HRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGGEL FSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSQNIAHRDVKPENLLYTSKEKDAVLKLTDFGF AKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGM KRRIRLGQYGFPKPEWADVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMEVPQTPLHTA RVLEEDKDHWDDVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQGGSSSASPGCNNQ hide sequence

RefSeq Acc Id:	XP_008764753 ⟸ XM_008766531
- Peptide Label:	isoform X1
- UniProtKB:	Q66H84 (UniProtKB/Swiss-Prot), A6I2W4 (UniProtKB/TrEMBL), A0A8I6AVR4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDGETAGEKGSLVPQPGALGAPALGGAPAPGVRREPKKYAVTDDYQLSKQVLGLGVNGKVLECY HRRSGQKCALKLLYDSPKARQEVDHHWQASGGPHIVRILDVYENMHHGKRCLLIVMECMEGGEL FSRIQERGDQAFTEREAAEIMRDIGTAIQFLHSQNIAHRDVKPENLLYTSKEKDAVLKLTDFGF AKETTQNALQTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGFPPFYSNTGQAISPGM KRRIRLGQYGFPKPEWADVSEDAKQLIRLLLKTDPTERLTIMQFMNHPWINQSMEVPQTPLHTA RVLEEDKDHWDDVKEEMTSALATMRVDYDQVKIKDLKTSNNRLLNKRRKKQGGSSSASPGCNNQ hide sequence

RefSeq Acc Id:

ENSRNOP00000020065 ⟸ ENSRNOT00000020065

RefSeq Acc Id:

ENSRNOP00000088134 ⟸ ENSRNOT00000114765

RefSeq Acc Id:

ENSRNOP00000096910 ⟸ ENSRNOT00000100521

RefSeq Acc Id:

ENSRNOP00000091496 ⟸ ENSRNOT00000094925

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q66H84-F1-model_v2	AlphaFold	Q66H84	1-384	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696263

Promoter ID:

EPDNEW_R6788

Type:

initiation region

Name:

Mapkapk3_1

Description:

mitogen-activated protein kinase-activated protein kinase 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	8	116,045,945 - 116,046,005	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1304980	AgrOrtholog
BioCyc Gene	G2FUF-29212	BioCyc
Ensembl Genes	ENSRNOG00000014832	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020065	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOT00000094925.1	UniProtKB/TrEMBL
	ENSRNOT00000100521.1	UniProtKB/TrEMBL
	ENSRNOT00000114765.1	UniProtKB/TrEMBL
Gene3D-CATH	4.10.1170.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7126359	IMAGE-MGC_LOAD
InterPro	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MAPKAPK_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:315994	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94118	IMAGE-MGC_LOAD
NCBI Gene	315994	ENTREZGENE
PANTHER	MAP KINASE-ACTIVATED PROTEIN KINASE 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SERINE/THREONINE-PROTEIN KINASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mapkapk3	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000014832	RatGTEx
SMART	S_TKc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6A779_RAT	UniProtKB/TrEMBL
	A0A8I6ABR6_RAT	UniProtKB/TrEMBL
	A0A8I6AVR4	ENTREZGENE, UniProtKB/TrEMBL
	A6I2W4	ENTREZGENE, UniProtKB/TrEMBL
	MAPK3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-08-08	Mapkapk3	MAPK activated protein kinase 3	Mapkapk3	mitogen-activated protein kinase-activated protein kinase 3	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	Mapkapk3	mitogen-activated protein kinase-activated protein kinase 3	Mapkapk3_predicted	mitogen-activated protein kinase-activated protein kinase 3 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Mapkapk3_predicted	mitogen-activated protein kinase-activated protein kinase 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)