Gene: Gfra2 (GDNF family receptor alpha 2) Rattus norvegicus
Symbol: Gfra2
Name: GDNF family receptor alpha 2
Description: ENCODES a protein that exhibits glial cell-derived neurotrophic factor receptor activity; INVOLVED IN negative regulation of protein autophosphorylation; nervous system development (ortholog); positive regulation of peptidyl-serine phosphorylation of STAT protein (ortholog); ASSOCIATED WITH Optic Nerve Injuries; Parkinsonian Disorders; FOUND IN anchored component of membrane (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 3H-1,2-dithiole-3-thione
Type: protein-coding
Also known as: GDNF family receptor alpha-2; glial cell line derived neurotrophic factor family receptor alpha 2; Retl2; tyrosine kinase receptor ligand 2
Homo sapiens (human) : GFRA2 (GDNF family receptor alpha 2)  HGNC  Alliance
Mus musculus (house mouse) : Gfra2 (glial cell line derived neurotrophic factor family receptor alpha 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gfra2 (GDNF family receptor alpha 2)
Pan paniscus (bonobo/pygmy chimpanzee) : GFRA2 (GDNF family receptor alpha 2)
Canis lupus familiaris (dog) : GFRA2 (GDNF family receptor alpha 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gfra2 (GDNF family receptor alpha 2)
Sus scrofa (pig) : GFRA2 (GDNF family receptor alpha 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01552,557,004 - 52,648,984 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01556,280,942 - 56,372,308 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41551,279,770 - 51,371,053 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11551,295,549 - 51,386,832 (+)NCBI
Celera1545,618,968 - 45,709,881 (+)NCBICelera
Cytogenetic Map15p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gfra2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61809
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE