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Gene: Exosc8 (exosome component 8) Rattus norvegicus
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Symbol: Exosc8
Name: exosome component 8
Description: Predicted to have identical protein binding activity and mRNA 3'-UTR AU-rich region binding activity. Predicted to be involved in RNA metabolic process. Predicted to localize to the cytoplasmic exosome (RNase complex); cytosol; and nuclear lumen. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia. Orthologous to human EXOSC8 (exosome component 8); PARTICIPATES IN RNA degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: exosome complex component RRP43; exosome complex exonuclease RRP43; LOC295050
Orthologs:
Homo sapiens (human) : EXOSC8 (exosome component 8)  HGNC  Alliance
Mus musculus (house mouse) : Exosc8 (exosome component 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Exosc8 (exosome component 8)
Pan paniscus (bonobo/pygmy chimpanzee) : EXOSC8 (exosome component 8)
Canis lupus familiaris (dog) : EXOSC8 (exosome component 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Exosc8 (exosome component 8)
Sus scrofa (pig) : EXOSC8 (exosome component 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02143,925,643 - 143,932,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2143,925,546 - 143,931,940 (-)Ensembl
Rnor_5.02160,331,306 - 160,337,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42143,954,943 - 143,961,239 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12143,905,006 - 143,911,553 (-)NCBI
Celera2133,415,207 - 133,421,503 (-)NCBICelera
Cytogenetic Map2q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
  
More on Exosc8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306169
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.