Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sacm1l | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | SACM1L (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SACM1L mRNA | CTD | PMID:22079256 | Sacm1l | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Sacm1l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SACM1L mRNA | CTD | PMID:36331819 | Sacm1l | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Sacm1l (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SACM1L mRNA | CTD | PMID:22206623 | Sacm1l | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Sacm1l (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SACM1L mRNA | CTD | PMID:22206623 | Sacm1l | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SACM1L mRNA | CTD | PMID:18796159 and PMID:21215274 | Sacm1l | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Sacm1l (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of SACM1L mRNA | CTD | PMID:26251327 | Sacm1l | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | SACM1L (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SACM1L mRNA | CTD | PMID:28628672 | Sacm1l | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SACM1L mRNA | CTD | PMID:16483693 | Sacm1l | Rat | antimycin A | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of SACM1L mRNA | CTD | PMID:33512557 | Sacm1l | Rat | aristolochic acid A | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SACM1L mRNA | CTD | PMID:33212167 | Sacm1l | Rat | arsenite(3-) | multiple interactions | ISO | SACM1L (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to SACM1L mRNA] | CTD | PMID:32406909 | Sacm1l | Rat | benzo[e]pyrene | increases methylation | ISO | SACM1L (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of SACM1L promoter | CTD | PMID:30157460 | Sacm1l | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SACM1L mRNA | CTD | PMID:25181051 and PMID:33296240 | Sacm1l | Rat | Bisphenol B | increases expression | ISO | SACM1L (Homo sapiens) | 6480464 | bisphenol B results in increased expression of SACM1L protein | CTD | PMID:34186270 | Sacm1l | Rat | bisphenol F | multiple interactions | ISO | SACM1L (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SACM1L mRNA | CTD | PMID:28628672 | Sacm1l | Rat | bisphenol F | increases expression | ISO | SACM1L (Homo sapiens) | 6480464 | bisphenol F results in increased expression of SACM1L protein | CTD | PMID:34186270 | Sacm1l | Rat | Brodifacoum | increases expression | EXP | | 6480464 | bromfenacoum results in increased expression of SACM1L protein | CTD | PMID:28903499 | Sacm1l | Rat | cadmium dichloride | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of SACM1L mRNA | CTD | PMID:38568856 | Sacm1l | Rat | chlorpyrifos | decreases expression | ISO | Sacm1l (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of SACM1L mRNA | CTD | PMID:37019170 | Sacm1l | Rat | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of SACM1L protein | CTD | PMID:34058248 | Sacm1l | Rat | copper(II) sulfate | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of SACM1L mRNA | CTD | PMID:19549813 | Sacm1l | Rat | crocidolite asbestos | decreases expression | ISO | Sacm1l (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of SACM1L mRNA | CTD | PMID:29279043 | Sacm1l | Rat | dexamethasone | multiple interactions | ISO | SACM1L (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SACM1L mRNA | CTD | PMID:28628672 | Sacm1l | Rat | diazinon | increases methylation | ISO | SACM1L (Homo sapiens) | 6480464 | Diazinon results in increased methylation of SACM1L gene | CTD | PMID:22964155 | Sacm1l | Rat | dicrotophos | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SACM1L mRNA | CTD | PMID:28302478 | Sacm1l | Rat | ethyl methanesulfonate | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of SACM1L mRNA | CTD | PMID:23649840 | Sacm1l | Rat | folic acid | multiple interactions | ISO | Sacm1l (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of SACM1L mRNA | CTD | PMID:22206623 | Sacm1l | Rat | folic acid | decreases expression | ISO | Sacm1l (Mus musculus) | 6480464 | Folic Acid results in decreased expression of SACM1L mRNA | CTD | PMID:25629700 | Sacm1l | Rat | formaldehyde | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of SACM1L mRNA | CTD | PMID:23649840 | Sacm1l | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SACM1L mRNA | CTD | PMID:22061828 and PMID:33387578 | Sacm1l | Rat | indometacin | multiple interactions | ISO | SACM1L (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SACM1L mRNA | CTD | PMID:28628672 | Sacm1l | Rat | ivermectin | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SACM1L protein | CTD | PMID:32959892 | Sacm1l | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of SACM1L mRNA | CTD | PMID:30467583 | Sacm1l | Rat | methapyrilene | increases methylation | ISO | SACM1L (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of SACM1L promoter | CTD | PMID:30157460 | Sacm1l | Rat | methyl methanesulfonate | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of SACM1L mRNA | CTD | PMID:23649840 | Sacm1l | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | Sacm1l (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of SACM1L protein | CTD | PMID:26558463 | Sacm1l | Rat | nickel sulfate | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | nickel sulfate results in decreased expression of SACM1L mRNA | CTD | PMID:16780908 | Sacm1l | Rat | paracetamol | increases expression | ISO | Sacm1l (Mus musculus) | 6480464 | Acetaminophen results in increased expression of SACM1L mRNA | CTD | PMID:17585979 | Sacm1l | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SACM1L mRNA | CTD | PMID:33387578 | Sacm1l | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Sacm1l (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SACM1L mRNA | CTD | PMID:36331819 | Sacm1l | Rat | pirinixic acid | increases expression | ISO | Sacm1l (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SACM1L mRNA | CTD | PMID:18301758 | Sacm1l | Rat | potassium chromate | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of SACM1L mRNA | CTD | PMID:22079256 | Sacm1l | Rat | potassium chromate | multiple interactions | ISO | SACM1L (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of SACM1L mRNA | CTD | PMID:22079256 | Sacm1l | Rat | resveratrol | multiple interactions | ISO | SACM1L (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of SACM1L mRNA | CTD | PMID:23557933 | Sacm1l | Rat | rotenone | increases expression | ISO | SACM1L (Homo sapiens) | 6480464 | Rotenone results in increased expression of SACM1L mRNA | CTD | PMID:33512557 | Sacm1l | Rat | SB 431542 | multiple interactions | ISO | SACM1L (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of SACM1L protein | CTD | PMID:37664457 | Sacm1l | Rat | sodium arsenate | increases expression | ISO | Sacm1l (Mus musculus) | 6480464 | sodium arsenate results in increased expression of SACM1L mRNA | CTD | PMID:21795629 | Sacm1l | Rat | sodium arsenite | decreases expression | ISO | SACM1L (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SACM1L mRNA | CTD | PMID:38568856 | Sacm1l | Rat | sodium fluoride | decreases expression | ISO | Sacm1l (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of SACM1L protein | CTD | PMID:28918527 | Sacm1l | Rat | succimer | multiple interactions | ISO | Sacm1l (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of SACM1L mRNA | CTD | PMID:21641980 | Sacm1l | Rat | tetrachloromethane | decreases expression | ISO | Sacm1l (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of SACM1L mRNA | CTD | PMID:31919559 | Sacm1l | Rat | tetracycline | increases expression | ISO | Sacm1l (Mus musculus) | 6480464 | Tetracycline results in increased expression of SACM1L mRNA | CTD | PMID:16917069 | Sacm1l | Rat | thapsigargin | increases expression | EXP | | 6480464 | Thapsigargin results in increased expression of SACM1L protein | CTD | PMID:35544339 | Sacm1l | Rat | titanium dioxide | decreases methylation | ISO | Sacm1l (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of SACM1L promoter | CTD | PMID:35295148 | Sacm1l | Rat | trichloroethene | decreases expression | ISO | Sacm1l (Mus musculus) | 6480464 | Trichloroethylene results in decreased expression of SACM1L mRNA | CTD | PMID:19448997 | Sacm1l | Rat | triphenyl phosphate | affects expression | ISO | SACM1L (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SACM1L mRNA | CTD | PMID:37042841 | Sacm1l | Rat | valproic acid | decreases methylation | ISO | SACM1L (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of SACM1L gene | CTD | PMID:29154799 | Sacm1l | Rat | valproic acid | affects expression | ISO | SACM1L (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SACM1L mRNA | CTD | PMID:25979313 | |