Sacm1l (SAC1 like phosphatidylinositide phosphatase) - Rat Genome Database

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Gene: Sacm1l (SAC1 like phosphatidylinositide phosphatase) Rattus norvegicus
Analyze
Symbol: Sacm1l
Name: SAC1 like phosphatidylinositide phosphatase
RGD ID: 69223
Description: Enables phosphatidylinositol bisphosphate phosphatase activity; phosphatidylinositol-3-phosphatase activity; and phosphatidylinositol-4-phosphate phosphatase activity. Involved in phosphatidylinositol dephosphorylation. Located in endoplasmic reticulum membrane and endoplasmic reticulum-plasma membrane contact site. Is integral component of endoplasmic reticulum membrane. Orthologous to human SACM1L (SAC1 like phosphatidylinositide phosphatase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: phosphatidylinositide phosphatase SAC1; phosphatidylinositol-3-phosphatase SAC1; phosphatidylinositol-4-phosphate phosphatase; Sac1; SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae); SAC1 (supressor of actin mutations 1, homolog)-like; SAC1 (supressor of actin mutations 1, homolog)-like (S. cerevisiae); SAC1 suppressor of actin mutations 1-like; SAC1 suppressor of actin mutations 1-like (yeast); suppressor of actin 1; suppressor of actin mutations 1-like protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28123,176,017 - 123,232,413 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8123,172,536 - 123,232,413 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8128,765,500 - 128,828,247 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08126,964,469 - 127,027,208 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08124,793,995 - 124,856,731 (+)NCBIRnor_WKY
Rnor_6.08132,607,166 - 132,663,502 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8132,607,166 - 132,663,502 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08131,759,866 - 131,816,202 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48128,302,927 - 128,359,950 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18128,322,663 - 128,379,687 (+)NCBI
Celera8122,286,384 - 122,342,572 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Dynamic formation of ER-PM junctions presents a lipid phosphatase to regulate phosphoinositides. Dickson EJ, etal., J Cell Biol. 2016 Apr 11;213(1):33-48. doi: 10.1083/jcb.201508106. Epub 2016 Apr 4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Functional characterization of a mammalian Sac1 and mutants exhibiting substrate-specific defects in phosphoinositide phosphatase activity. Nemoto Y, etal., J Biol Chem 2000 Nov 3;275(44):34293-305.
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
8. JNK3 couples the neuronal stress response to inhibition of secretory trafficking. Yang G, etal., Sci Signal. 2013 Jul 9;6(283):ra57. doi: 10.1126/scisignal.2003727.
Additional References at PubMed
PMID:22632720   PMID:24209621   PMID:25013167   PMID:29461204   PMID:30659099   PMID:31505169   PMID:31806350  


Genomics

Comparative Map Data
Sacm1l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28123,176,017 - 123,232,413 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8123,172,536 - 123,232,413 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8128,765,500 - 128,828,247 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.08126,964,469 - 127,027,208 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.08124,793,995 - 124,856,731 (+)NCBIRnor_WKY
Rnor_6.08132,607,166 - 132,663,502 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8132,607,166 - 132,663,502 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08131,759,866 - 131,816,202 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48128,302,927 - 128,359,950 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18128,322,663 - 128,379,687 (+)NCBI
Celera8122,286,384 - 122,342,572 (+)NCBICelera
Cytogenetic Map8q32NCBI
SACM1L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38345,689,396 - 45,745,409 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl345,689,056 - 45,745,409 (+)EnsemblGRCh38hg38GRCh38
GRCh37345,730,888 - 45,786,901 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36345,705,947 - 45,761,905 (+)NCBINCBI36Build 36hg18NCBI36
Build 34345,705,946 - 45,761,904NCBI
Celera345,668,700 - 45,724,522 (+)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef345,775,115 - 45,830,941 (+)NCBIHuRef
CHM1_1345,680,731 - 45,736,559 (+)NCBICHM1_1
T2T-CHM13v2.0345,705,375 - 45,761,083 (+)NCBIT2T-CHM13v2.0
Sacm1l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399123,358,818 - 123,421,665 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9123,358,824 - 123,421,665 (+)EnsemblGRCm39 Ensembl
GRCm389123,529,753 - 123,592,600 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9123,529,759 - 123,592,600 (+)EnsemblGRCm38mm10GRCm38
MGSCv379123,439,000 - 123,501,716 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369123,378,580 - 123,441,296 (+)NCBIMGSCv36mm8
Celera9123,982,316 - 124,047,496 (+)NCBICelera
Cytogenetic Map9F4NCBI
cM Map974.08NCBI
Sacm1l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542026,229,840 - 26,280,516 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542026,231,597 - 26,280,516 (-)NCBIChiLan1.0ChiLan1.0
SACM1L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1346,704,539 - 46,760,105 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl346,704,565 - 46,760,104 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0345,596,775 - 45,652,482 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SACM1L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,731,674 - 42,791,455 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2042,720,249 - 42,791,402 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2042,648,744 - 42,708,307 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02043,216,790 - 43,276,240 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2043,216,794 - 43,276,251 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12042,457,062 - 42,516,486 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02042,864,579 - 42,923,977 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02043,139,544 - 43,199,143 (-)NCBIUU_Cfam_GSD_1.0
Sacm1l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118197,843,903 - 197,900,798 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936695196,238 - 253,128 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SACM1L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1328,817,132 - 28,891,685 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11328,816,977 - 28,906,503 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21331,719,695 - 31,794,148 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SACM1L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1227,159,701 - 7,214,368 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl227,159,809 - 7,214,555 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041159,951,795 - 160,006,471 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sacm1l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473075,113,012 - 75,169,561 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473075,107,294 - 75,169,527 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
D8Rat116  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28123,180,023 - 123,180,222 (+)MAPPERmRatBN7.2
Rnor_6.08132,611,122 - 132,611,318NCBIRnor6.0
Rnor_5.08131,763,822 - 131,764,018UniSTSRnor5.0
RGSC_v3.48128,306,882 - 128,307,079RGDRGSC3.4
RGSC_v3.48128,306,883 - 128,307,079UniSTSRGSC3.4
RGSC_v3.18128,326,536 - 128,326,932RGD
Celera8122,290,340 - 122,290,536UniSTS
SHRSP x BN Map884.17RGD
SHRSP x BN Map884.17UniSTS
Cytogenetic Map8q32UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:444
Count of miRNA genes:245
Interacting mature miRNAs:302
Transcripts:ENSRNOT00000007223
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 41 57 41 19 41 8 8 74 35 36 11 8
Low 2 3 5
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007223   ⟹   ENSRNOP00000007223
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8123,186,796 - 123,232,413 (+)Ensembl
Rnor_6.0 Ensembl8132,607,166 - 132,663,502 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000109426   ⟹   ENSRNOP00000080652
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8123,172,536 - 123,232,413 (+)Ensembl
RefSeq Acc Id: NM_001357497   ⟹   NP_001344426
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,176,017 - 123,232,413 (+)NCBI
RefSeq Acc Id: NM_053798   ⟹   NP_446250
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,176,017 - 123,232,413 (+)NCBI
Rnor_6.08132,607,166 - 132,663,502 (+)NCBI
Rnor_5.08131,759,866 - 131,816,202 (+)NCBI
RGSC_v3.48128,302,927 - 128,359,950 (+)RGD
Celera8122,286,384 - 122,342,572 (+)RGD
Sequence:
RefSeq Acc Id: XM_039080705   ⟹   XP_038936633
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,176,057 - 123,232,413 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001344426 (Get FASTA)   NCBI Sequence Viewer  
  NP_446250 (Get FASTA)   NCBI Sequence Viewer  
  XP_038936633 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL76757 (Get FASTA)   NCBI Sequence Viewer  
  EDL76758 (Get FASTA)   NCBI Sequence Viewer  
  Q9ES21 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_446250   ⟸   NM_053798
- Peptide Label: isoform 1
- UniProtKB: Q9ES21 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000007223   ⟸   ENSRNOT00000007223
RefSeq Acc Id: NP_001344426   ⟸   NM_001357497
- Peptide Label: isoform 1x
RefSeq Acc Id: XP_038936633   ⟸   XM_039080705
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000080652   ⟸   ENSRNOT00000109426
Protein Domains
SAC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ES21-F1-model_v2 AlphaFold Q9ES21 1-587 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696410
Promoter ID:EPDNEW_R6935
Type:initiation region
Name:Sacm1l_1
Description:SAC1 like phosphatidylinositide phosphatase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08132,607,110 - 132,607,170EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69223 AgrOrtholog
BioCyc Gene G2FUF-28612 BioCyc
BioCyc Pathway PWY-6368 [3-phosphoinositide degradation] BioCyc
Ensembl Genes ENSRNOG00000005149 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000007223.6 UniProtKB/TrEMBL
  ENSRNOP00000080652 ENTREZGENE
  ENSRNOP00000080652.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007223.6 UniProtKB/TrEMBL
  ENSRNOT00000109426 ENTREZGENE
  ENSRNOT00000109426.1 UniProtKB/TrEMBL
InterPro SAC_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:116482 UniProtKB/Swiss-Prot
NCBI Gene 116482 ENTREZGENE
Pfam Syja_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sacm1l PhenoGen
PROSITE SAC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC217389
UniProt A0A8I5ZR90_RAT UniProtKB/TrEMBL
  A0A8L2Q2L9_RAT UniProtKB/TrEMBL
  Q9ES21 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-19 Sacm1l  SAC1 like phosphatidylinositide phosphatase  Sacm1l  SAC1 suppressor of actin mutations 1-like (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Sacm1l  SAC1 suppressor of actin mutations 1-like (yeast)  Sacm1l  SAC1 (suppressor of actin mutations 1, homolog)-like (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Sacm1l  SAC1 (supressor of actin mutations 1, homolog)-like (S. cerevisiae)       Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to the endoplasmic reticulum 68842
gene_expression expressed in cerebellar Purkinje cells 68842