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Gene: Sacm1l (SAC1 suppressor of actin mutations 1-like (yeast)) Mus musculus
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Symbol: Sacm1l
Name: SAC1 suppressor of actin mutations 1-like (yeast)
Description: This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylinositol 4-phosphate, and phosphatidylinositol 3,5-bisphosphate. Deletion of this gene in mouse results in preimplantation lethality. Other studies suggest that this gene is also involved in the organization of golgi membranes and mitotic spindles. Two isoforms are predicted to be produced from the same mRNA by the use of alternative in-frame translation termination codons via a stop codon readthrough mechanism. [provided by RefSeq, Dec 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: mKIAA0851; phosphatidylinositide phosphatase SAC1; polyphosphatidylinositol phosphatase; SAC1; Sac1p; suppressor of actin mutations 1-like protein
Orthologs:
Homo sapiens (human) : SACM1L (SAC1 like phosphatidylinositide phosphatase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sacm1l (SAC1 like phosphatidylinositide phosphatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sacm1l (SAC1 like phosphatidylinositide phosphatase)
Pan paniscus (bonobo/pygmy chimpanzee) : SACM1L (SAC1 like phosphatidylinositide phosphatase)
Canis lupus familiaris (dog) : SACM1L (SAC1 like phosphatidylinositide phosphatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sacm1l (SAC1 like phosphatidylinositide phosphatase)
Sus scrofa (pig) : SACM1L (SAC1 like phosphatidylinositide phosphatase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389123,529,753 - 123,592,600 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379123,439,000 - 123,501,716 (+)NCBIGRCm37mm9NCBIm37
MGSCv369123,378,580 - 123,441,296 (+)NCBImm8
Celera9123,982,316 - 124,047,496 (+)NCBICelera
Cytogenetic Map9 F4NCBI
cM Map974.08NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Sacm1l
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735467
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.