Tmem171 (transmembrane protein 171)

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Gene: Tmem171 (transmembrane protein 171) Rattus norvegicus

Analyze

Symbol:

Tmem171

Name:

transmembrane protein 171

RGD ID:

1359492

Description:

Predicted to be located in membrane. Orthologous to human TMEM171 (transmembrane protein 171); INTERACTS WITH (+)-schisandrin B; acetamide; acrylamide.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

parturition-related protein 2; proline-rich protein PRP2; Prp2

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TMEM171 (transmembrane protein 171)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Tmem171 (transmembrane protein 171)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tmem171 (transmembrane protein 171)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TMEM171 (transmembrane protein 171)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TMEM171 (transmembrane protein 171)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tmem171 (transmembrane protein 171)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TMEM171 (transmembrane protein 171)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TMEM171 (transmembrane protein 171)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tmem171 (transmembrane protein 171)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TMEM171 (transmembrane protein 171)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tmem171 (transmembrane protein 171)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tmem171	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	30,035,278 - 30,045,996 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	30,035,278 - 30,045,049 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	37,093,085 - 37,106,136 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	2,313,122 - 2,326,173 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	30,003,666 - 30,013,446 (-)	NCBI	Rnor_WKY
Rnor_6.0	2	28,791,831 - 28,802,135 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	28,791,875 - 28,801,223 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	47,889,908 - 47,900,063 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	29,301,092 - 29,310,650 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	29,221,460 - 29,231,019 (-)	NCBI
Celera	2	26,071,073 - 26,080,320 (-)	NCBI		Celera
Cytogenetic Map	2	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

7,9-dihydro-1H-purine-2,6,8(3H)-trione (ISO)

acetamide (EXP)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

calcium silicate (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

chrysene (ISO)

CU-O LINKAGE (ISO)

dexamethasone (ISO)

dibenz[a,h]anthracene (ISO)

dichloroacetic acid (ISO)

dioxygen (ISO)

ethanol (EXP)

folic acid (ISO)

fonofos (ISO)

gentamycin (EXP)

indole-3-methanol (EXP)

indometacin (ISO)

lipopolysaccharide (ISO)

N-nitrosodiethylamine (EXP)

nickel sulfate (ISO)

nitrofen (EXP)

paraquat (EXP)

parathion (ISO)

PCB138 (ISO)

pentanal (ISO)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (EXP)

pirinixic acid (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

succimer (ISO)

temozolomide (ISO)

terbufos (ISO)

tetrachloromethane (EXP)

tetraphene (ISO)

thioacetamide (EXP)

titanium dioxide (EXP,ISO)

tributylstannane (EXP)

trichloroethene (EXP)

trovafloxacin (ISO)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	GOA pipeline	RGD automated data pipeline
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Tmem171
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	30,035,278 - 30,045,996 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	30,035,278 - 30,045,049 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	37,093,085 - 37,106,136 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	2,313,122 - 2,326,173 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	30,003,666 - 30,013,446 (-)	NCBI	Rnor_WKY
Rnor_6.0	2	28,791,831 - 28,802,135 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	28,791,875 - 28,801,223 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	47,889,908 - 47,900,063 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	29,301,092 - 29,310,650 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	29,221,460 - 29,231,019 (-)	NCBI
Celera	2	26,071,073 - 26,080,320 (-)	NCBI		Celera
Cytogenetic Map	2	q12	NCBI

TMEM171
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	73,120,575 - 73,131,809 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	5	73,120,569 - 73,131,809 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	72,416,402 - 72,427,636 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	72,452,158 - 72,463,397 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	68,311,763 - 68,323,014 (+)	NCBI		Celera
Cytogenetic Map	5	q13.2	NCBI
HuRef	5	67,622,070 - 67,633,327 (+)	NCBI		HuRef
CHM1_1	5	71,849,116 - 71,860,378 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	73,601,908 - 73,613,146 (+)	NCBI		T2T-CHM13v2.0

Tmem171
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	98,822,744 - 98,832,142 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	98,822,743 - 98,831,342 (-)	Ensembl		GRCm39 Ensembl
GRCm38	13	98,686,236 - 98,695,654 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	98,686,235 - 98,694,834 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	99,456,193 - 99,464,786 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	99,786,395 - 99,794,988 (-)	NCBI		MGSCv36	mm8
Celera	13	102,345,922 - 102,354,526 (-)	NCBI		Celera
Cytogenetic Map	13	D1	NCBI

Tmem171
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	27,457,185 - 27,464,513 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	27,457,245 - 27,466,484 (-)	NCBI	ChiLan1.0	ChiLan1.0

TMEM171
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	5	40,337,014 - 40,348,485 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	42,181,966 - 42,193,088 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	42,781,305 - 42,789,684 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	42,781,305 - 42,789,684 (-)	Ensembl	panpan1.1		panPan2

TMEM171
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	2	56,036,463 - 56,044,443 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	2	56,037,975 - 56,044,464 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	2	53,008,185 - 53,018,390 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	2	56,558,208 - 56,566,307 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	2	56,559,817 - 56,566,307 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	2	53,617,060 - 53,627,212 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	2	54,384,978 - 54,395,341 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	2	55,275,830 - 55,286,629 (+)	NCBI		UU_Cfam_GSD_1.0

Tmem171
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	187,446,269 - 187,455,734 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936549	3,403,222 - 3,412,348 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936549	3,403,250 - 3,411,897 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TMEM171
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	82,287,158 - 82,297,856 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	82,287,211 - 82,297,855 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	83,995,709 - 84,006,354 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TMEM171
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	67,463,098 - 67,476,538 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	67,462,987 - 67,475,326 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666049	16,230,129 - 16,241,665 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tmem171
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624905	2,167,045 - 2,177,234 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624905	2,167,147 - 2,176,964 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tmem171
55 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	66
Count of miRNA genes:	56
Interacting mature miRNAs:	57
Transcripts:	ENSRNOT00000020726
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631682	Bp115	Blood pressure QTL 115	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	1	37410502	Rat
738010	Lnnr3	Liver neoplastic nodule remodeling QTL 3	2.94		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	2	1	41244106	Rat
61355	Bp36	Blood pressure QTL 36	2.9		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	2	5873687	102844969	Rat
1600379	Mcs18	Mammary carcinoma susceptibility QTL 18	2.6		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	7887772	42804738	Rat
738012	Anxrr3	Anxiety related response QTL 3	3.8		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	2	9023519	54023519	Rat
10755430	Coatc6	Coat color QTL 6		0.02576	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	2	11591100	56591100	Rat
1578664	Bmd9	Bone mineral QTL density 9	5		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	2	11852062	49003364	Rat
731184	Mamtr4	Mammary tumor resistance QTL 4		0.0003	mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	2	16491740	61491740	Rat
1357990	Ael1	Aortic elastin QTL 1	3.1	0.00091	aorta elastin amount (VT:0003905)	aortic elastin	2	19076825	64076825	Rat
731167	Glom4	Glomerulus QTL 4	2.4	0.0082	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	2	20304672	65304672	Rat
2300168	Bmd47	Bone mineral density QTL 47	6.6	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	2	20662448	65662448	Rat
10402051	Gdil2	Gastrointestinal dilation QTL 2			enteric ganglion morphology trait (VT:0001045)	length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)	2	24903853	74786777	Rat
1302794	Stl27	Serum triglyceride level QTL 27	4.4	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	2	25413423	143657569	Rat
1358894	Kidm24	Kidney mass QTL 24	4.03		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358899	Kidm23	Kidney mass QTL 23	3.88		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358901	Cm38	Cardiac mass QTL 38	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358904	Cm39	Cardiac mass QTL 39	2.26		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	157142209	Rat
1358910	Kidm27	Kidney mass QTL 27	5.77		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358911	Kidm28	Kidney mass QTL 28	5.42		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	25413423	157142209	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	25413423	203928301	Rat
1358887	Bw50	Body weight QTL 50	2.39		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1358908	Bw49	Body weight QTL 49	3.36		body mass (VT:0001259)	body weight (CMO:0000012)	2	25413652	157142078	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	26917817	81754745	Rat
1354617	Bp240	Blood pressure QTL 240	4		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	81754745	Rat
1354603	Bp243	Blood pressure QTL 243	3.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	26917817	127469484	Rat
2290453	Scl55	Serum cholesterol level QTL 55	2.83		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	26917817	136917119	Rat
1331764	Bp205	Blood pressure QTL 205	3.476		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	26999571	43154682	Rat
1643006	Pain1	Pain QTL 1	3.63	0.005	mechanical nociception trait (VT:0002734)	self mutilation severity score (CMO:0002145)	2	26999571	48268661	Rat
9590095	Sffal3	Serum free fatty acids level QTL 3	6.78	0.001	blood free fatty acid amount (VT:0001553)	plasma free fatty acids level (CMO:0000546)	2	27157160	72157160	Rat
1300160	Hrtrt3	Heart rate QTL 3	3.62		heart pumping trait (VT:2000009)	absolute change in heart rate (CMO:0000534)	2	29971593	51729300	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	10								21	4
Low		33	30	24	2	24				14	35	11
Below cutoff			25	15	10	15	5	5	52		2		5

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001401800	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006231834	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008760660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101887	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039101888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY185507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473955	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000020726 ⟹ ENSRNOP00000020726

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	30,035,278 - 30,045,049 (-)	Ensembl
Rnor_6.0 Ensembl	2	28,791,892 - 28,801,223 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000089293 ⟹ ENSRNOP00000071996

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	28,791,875 - 28,799,266 (-)	Ensembl

RefSeq Acc Id:

NM_001013903 ⟹ NP_001013925

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	30,035,339 - 30,045,049 (-)	NCBI
Rnor_6.0	2	28,791,892 - 28,801,223 (-)	NCBI
Rnor_5.0	2	47,889,908 - 47,900,063 (-)	NCBI
RGSC_v3.4	2	29,301,092 - 29,310,650 (-)	RGD
Celera	2	26,071,073 - 26,080,320 (-)	RGD

Sequence:

show sequence

GCGGAGAGTCCCAGGACCAAGGCAGAGTCTGCAACTGTCGGAGGGAAGGACACACATTCCTCTT
TCACATCGGGGAGCAGTGAGGAGGCCTTTTCTTTTCTGGCCATGTCTTCTGTAGGAACTGCTGA
GCCAGACGGAGACCAGAGGGACCGACAAGTCAGCAAACTCATCTTCTTCCTCTTTGTCTTCGGT
GCAGTCCTGTTGTGTGTGGGGGTCCTGATCTCCATCTTTGGGTACCAGGCATGCCAATATAAGC
CTCTCTCACACTGCAGCATGGTGCTAAAGATTGCTGGGCCTTCCTGTGCAGTGATGGGGCTGGG
AACTGTGATTCTAGCCCGGTCCCGGGCACGCCTGCAACTGAGGGAGCGACAGCGGCAGGGCCAT
CAGGACCCTGACCAATCCTTCTTCTGTGGAGAGAGCCGCCAGTTTGCCCAGTGTCTCATCTTTG
GGTTCTTGTTTCTGACCAGTGGCATGCTCATTAGCATACTGGGTATCTGGGTGCCAGGATGTGG
CTCAGACTGGGCACAGGAACCACTGAACGAGACAAACAGTGGAGAAGGAGAACCCCAGATCTGC
AGCTTCCTTTCTCTGCAGATCATGGGGCCCTTGATTGTGCTCGTAGGATTGTGTTTCTTTGTGG
TGGCCCATGTTAAGAAGAAAAGCAACCTGAGTTCAAGCCGAGATACCTCTGAAATCGAAGGTGG
ACACACCCACAGTACAGAACCTGTCCACATCACTGTGGGTGACTCAGTGATAATATTCCCGCCC
CCTCCACCACCTTACTTTGCTGAGTCTTCAGCAGCAGCTCCCTCTCCTGGGGCTAACAGCCTGC
ACCGGATCGAAAACCCACCTTCCTACTCCAGTCTTTTTAATCTCAGCAGGACCCCAACTCCTGA
GAACCAGGGAGCAGCCTCTGAGAGAGATCGGGAAGTCATATACACCATTTCTGGGCCAGGTTCA
TCCTCTGAGAGTTCACACACTGGGCATCTTCCGCTGGACCTGCCCCCGAGATATGAAGAAAAAG
AGACTGCTCCAGCCACACCCTTGGGTGCCCCTTCTGAGTCATCCCCACCGTGAGCTATGGACTC
AGGCAGATGATGGAC

hide sequence

RefSeq Acc Id:

XM_006231834 ⟹ XP_006231896

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	30,035,278 - 30,045,887 (-)	NCBI
Rnor_6.0	2	28,791,831 - 28,802,133 (-)	NCBI
Rnor_5.0	2	47,889,908 - 47,900,063 (-)	NCBI

Sequence:

show sequence

TAGTTGTCAAGTGTCACGGGGCAGGTTACAAATAGCATGGGGATTAGCAAACCCATCAGACACA
CTGTTCAAGGGCAGGAAAAGTTAACAGTTTAATCTCCGGAGCACCAGGAAGGGTGTTTTATGGC
ATAGGAGGGCTGGATGCAAATCTATGACCAGAAAGGGACAAGGGTGACCCACCACAGGACCTCT
GGGGATAAGCTTCAGTCTAGGAGTTAGGCTGTCATGTTGAATGCTAGCACACGAGGTCTCCACG
GGTTTTATTCTCCATGGGTCCCGGGGGGGGGGTCCCCATATTCTCTTATACAAAGCTCCCTGTG
AGGCTCTAGGTCCTGAAACCCTGTCAAGGTCTCAGAGCAGTAGAAGGACCATCTGCCTTCGACT
GGCAGTGGCGTCAGAACGACAGGGATCCCTGCTCAGCCACAGACCGAGGCCCTGGGCTTTCCCT
GTTGCTCTGCTCAGGGATCGGCTATCCCACAGCAGGCCCCCTCCCCCTCCCGGATCTCTGCACC
TAGCCTGCGAAGGGACCAGCTCCTTTCTCAGCTGCCTGCCTCCGTGTCGCCACCGCACGCAGCC
CCGGCTGCCAGTGGGTACAATCTGGACTCGCTGGTACCCACAACTTGGTGGAGCGAGCCCATCT
GCCTTCACCCCACGCCGGATCCCTCGCTCGCACCGACAAATCCTCTGGTCCCAGGGCCGCGAAG
TTGACCCTAGTTCCGCACTCCGGAGTGGAGCGCCGGTGCCCCAGGAGGGCAGCGCCCGGCAGCG
GCCAGATCCCACCGGCCAGCCCTGCCCTGCCCCGCCTGGCCGCCGCACCCGCGAGCCCGGCACT
GCCTGGCCCTCTGCACACCGAGGAGGCCCGCCCTCTGCGCCCGGACGCGCAGAGGGTGTGCGTG
GAGCCAGGGGTGTGGCGGAGAGTCCCAGGACCAAGGCAGAGTCTGCAACTGTCAGAGGGAAGGA
CACACATTCCTCTTTCACATCGGGGAGCAGTGAGGAGGCCTTTTCTTTTCTGGCCATGTCTTCT
GTAGGAACTGCTGAGCCAGACGGAGACCAGAGGGACCGACAAGTCAGCAAACTCATCTTCTTCC
TCTTTGTCTTCGGTGCAGTCCTGTTGTGTGTGGGGATCCTGATCTCCATCTTTGGGTACCAGGC
ATGCCAATATAAGCCTCTCTCACACTGCAGCATGGTGCTAAAGATTGCTGGGCCTTCCTGTGCA
GTGATGGGGCTGGGAACTGTGATTCTAGCCCGGTCCCGGGCACGCCTGCAACTGAGGGAGCGAC
AGCGGCAGGGCCATCAGGACCCTGACCAATCCTTCTTCTGTGGAGAGAGCCGCCAGTTTGCCCA
GTGTCTCATCTTTGGGTTCTTGTTTCTGACCAGTGGCATGCTCATTAGCATACTGGGTATCTGG
GTGCCAGGATGTGGCTCAGACTGGGCACAGGAACCACTGAACGAGACAAACAGTGGAGAAGGAG
AACCCCAGATCTGCAGCTTCCTTTCTCTGCAGATCATGGGGCCCTTGATTGTGCTCGTAGGATT
GTGTTTCTTTGTGGTGGCCCATGTTAAGAAGAAAAGCAACCTGAGTTCAAGCCGAGATACCTCT
GAAATCGAAGGTGGACACACCCACAGTACAGAACCTGTCCACATCACTGTGGGTGACTCAGTGA
TAATATTCCCGCCCCCTCCACCACCTTACTTTGCTGAGTCTTCAGCAGCAGCTCCCTCTCCTGG
GGCTAACAGCCTGCACCGGATCGAAAACCCACCTTCCTACTCCAGTCTTTTTAATCTCAGGACC
CCAACTCCTGAGAACCAGGGAGCAGCCTCTGAGAGAGATCGGGAAGTCATATACACCATTTCTG
GGCCAGGTTCATCCTCCGAGAGTTCACACACTGGGCATCTTCCGCTGGACCTGCCCCCGAGATA
TGAAGAAAAAGAGACTGCTCCAGCCACACCCTTGGGTGCCCCTTCTGAGTCATCCCCACCGTGA
GCTATGGACTCAGGCAGATGATGGACAGTTTTATATATATCATGGATTGTTTTTTATTTAATTT
TTTTAATAAAAAATACAATAACA

hide sequence

RefSeq Acc Id:

XM_039101887 ⟹ XP_038957815

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	30,035,278 - 30,045,996 (-)	NCBI

RefSeq Acc Id:

XM_039101888 ⟹ XP_038957816

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	2	30,035,278 - 30,045,153 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001013925	(Get FASTA)	NCBI Sequence Viewer
	NP_001388729	(Get FASTA)	NCBI Sequence Viewer
	XP_006231896	(Get FASTA)	NCBI Sequence Viewer
	XP_038957815	(Get FASTA)	NCBI Sequence Viewer
	XP_038957816	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAO67350	(Get FASTA)	NCBI Sequence Viewer
	EDM10155	(Get FASTA)	NCBI Sequence Viewer
	Q6K0P5	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001013925 ⟸ NM_001013903

- Sequence:

show sequence

MSSVGTAEPDGDQRDRQVSKLIFFLFVFGAVLLCVGVLISIFGYQACQYKPLSHCSMVLKIAGP
SCAVMGLGTVILARSRARLQLRERQRQGHQDPDQSFFCGESRQFAQCLIFGFLFLTSGMLISIL
GIWVPGCGSDWAQEPLNETNSGEGEPQICSFLSLQIMGPLIVLVGLCFFVVAHVKKKSNLSSSR
DTSEIEGGHTHSTEPVHITVGDSVIIFPPPPPPYFAESSAAAPSPGANSLHRIENPPSYSSLFN
LSRTPTPENQGAASERDREVIYTISGPGSSSESSHTGHLPLDLPPRYEEKETAPATPLGAPSES
SPP

hide sequence

RefSeq Acc Id:

XP_006231896 ⟸ XM_006231834

- Peptide Label:

isoform X1

- Sequence:

show sequence

MLAHEVSTGFILHGSRGGGPHILLYKAPCEALGPETLSRSQSSRRTICLRLAVASERQGSLLSH
RPRPWAFPVALLRDRLSHSRPPPPPGSLHLACEGTSSFLSCLPPCRHRTQPRLPVGTIWTRWYP
QLGGASPSAFTPRRIPRSHRQILWSQGREVDPSSALRSGAPVPQEGSARQRPDPTGQPCPAPPG
RRTREPGTAWPSAHRGGPPSAPGRAEGVRGARGVAESPRTKAESATVRGKDTHSSFTSGSSEEA
FSFLAMSSVGTAEPDGDQRDRQVSKLIFFLFVFGAVLLCVGILISIFGYQACQYKPLSHCSMVL
KIAGPSCAVMGLGTVILARSRARLQLRERQRQGHQDPDQSFFCGESRQFAQCLIFGFLFLTSGM
LISILGIWVPGCGSDWAQEPLNETNSGEGEPQICSFLSLQIMGPLIVLVGLCFFVVAHVKKKSN
LSSSRDTSEIEGGHTHSTEPVHITVGDSVIIFPPPPPPYFAESSAAAPSPGANSLHRIENPPSY
SSLFNLRTPTPENQGAASERDREVIYTISGPGSSSESSHTGHLPLDLPPRYEEKETAPATPLGA
PSESSPP

hide sequence

RefSeq Acc Id:

ENSRNOP00000071996 ⟸ ENSRNOT00000089293

RefSeq Acc Id:

ENSRNOP00000020726 ⟸ ENSRNOT00000020726

RefSeq Acc Id:	XP_038957815 ⟸ XM_039101887
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038957816 ⟸ XM_039101888
- Peptide Label:	isoform X3

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6K0P5-F1-model_v2	AlphaFold	Q6K0P5	1-323	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691092

Promoter ID:

EPDNEW_R1617

Type:

single initiation site

Name:

Tmem171_1

Description:

transmembrane protein 171

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	28,801,177 - 28,801,237	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359492	AgrOrtholog
BioCyc Gene	G2FUF-54713	BioCyc
Ensembl Genes	ENSRNOG00000015449	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000020726	ENTREZGENE
	ENSRNOP00000020726.3	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020726	ENTREZGENE
	ENSRNOT00000020726.4	UniProtKB/TrEMBL
InterPro	TMEM171	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:293634	UniProtKB/Swiss-Prot
NCBI Gene	293634	ENTREZGENE
PANTHER	PTHR31617	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TRANSMEMBRANE PROTEIN 171	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	TMEM171	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Tmem171	PhenoGen
UniProt	F1LQN5	ENTREZGENE, UniProtKB/TrEMBL
	Q6K0P5	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-06	Tmem171	transmembrane protein 171	Prp2	proline-rich protein PRP2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-07-29	Prp2	proline-rich protein PRP2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar