1,2-dimethylhydrazine affects expression ISO Ptpn6 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine affects the expression of PTPN6 mRNA CTD PMID:22206623 17beta-estradiol increases expression ISO Ptpn6 (Mus musculus) 6480464 Estradiol results in increased expression of PTPN6 mRNA CTD PMID:17578864 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO PTPN6 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ptpn6 (Mus musculus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTPN6 gene] CTD PMID:20819909 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of PTPN6 mRNA CTD PMID:33387578 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PTPN6 mRNA CTD PMID:34747641 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO PTPN6 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of PTPN6 mRNA and Tetrachlorodibenzodioxin results in increased expression of PTPN6 protein CTD PMID:27546522 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO PTPN6 (Homo sapiens) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTPN6 mRNA] and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTPN6 promoter] CTD PMID:27546522 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ptpn6 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PTPN6 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ptpn6 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PTPN6 mRNA CTD PMID:20819909 2,4,6-tribromophenol decreases expression ISO PTPN6 (Homo sapiens) 6480464 2 more ... CTD PMID:31675489 2,4-diaminotoluene increases expression ISO Ptpn6 (Mus musculus) 6480464 2 and 4-diaminotoluene results in increased expression of PTPN6 mRNA CTD PMID:20713471 2,6-dinitrotoluene affects expression EXP 6480464 2 and 6-dinitrotoluene affects the expression of PTPN6 mRNA CTD PMID:21346803 3,3',5,5'-tetrabromobisphenol A decreases expression ISO PTPN6 (Homo sapiens) 6480464 tetrabromobisphenol A results in decreased expression of PTPN6 protein CTD PMID:31675489 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1 and 2-dithiol-3-thione results in decreased expression of PTPN6 mRNA CTD PMID:19162173 4,4'-sulfonyldiphenol affects methylation ISO Ptpn6 (Mus musculus) 6480464 bisphenol S affects the methylation of PTPN6 gene CTD PMID:31683443 5-aza-2'-deoxycytidine decreases methylation ISO PTPN6 (Homo sapiens) 6480464 Decitabine results in decreased methylation of PTPN6 promoter CTD PMID:19551406 5-aza-2'-deoxycytidine multiple interactions ISO PTPN6 (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with Decitabine] results in increased expression of PTPN6 mRNA CTD PMID:24762999 5-aza-2'-deoxycytidine increases expression ISO PTPN6 (Homo sapiens) 6480464 Decitabine results in increased expression of PTPN6 mRNA and Decitabine results in increased expression of PTPN6 protein CTD PMID:17343198 more ... acetamide increases expression EXP 6480464 acetamide results in increased expression of PTPN6 mRNA CTD PMID:31881176 acrylamide increases expression ISO PTPN6 (Homo sapiens) 6480464 Acrylamide results in increased expression of PTPN6 mRNA CTD PMID:32763439 afimoxifene decreases activity ISO PTPN6 (Homo sapiens) 6480464 afimoxifene results in decreased activity of PTPN6 protein CTD PMID:17272397 aflatoxin B1 decreases methylation ISO PTPN6 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of PTPN6 gene CTD PMID:27153756 aflatoxin B1 increases methylation ISO PTPN6 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of PTPN6 intron CTD PMID:30157460 all-trans-retinoic acid increases expression ISO PTPN6 (Homo sapiens) 6480464 Tretinoin results in increased expression of PTPN6 mRNA CTD PMID:33167477 all-trans-retinol multiple interactions EXP 6480464 Vitamin A affects the localization of and affects the phosphorylation of PTPN6 protein CTD PMID:15963505 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PTPN6 mRNA CTD PMID:16483693 anthranilic acid multiple interactions ISO PTPN6 (Homo sapiens) 6480464 [oxovanadium IV binds to anthranilic acid analog] which results in decreased activity of PTPN6 protein CTD PMID:22864521 antirheumatic drug decreases expression ISO PTPN6 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of PTPN6 mRNA CTD PMID:24449571 aristolochic acid A increases expression ISO PTPN6 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of PTPN6 mRNA CTD PMID:33212167 arsane affects methylation ISO PTPN6 (Homo sapiens) 6480464 Arsenic affects the methylation of PTPN6 gene CTD PMID:25304211 arsane increases expression ISO PTPN6 (Homo sapiens) 6480464 Arsenic results in increased expression of PTPN6 protein CTD PMID:35031324 arsane decreases expression ISO PTPN6 (Homo sapiens) 6480464 Arsenic results in decreased expression of PTPN6 mRNA CTD PMID:35031324 arsenic atom affects methylation ISO PTPN6 (Homo sapiens) 6480464 Arsenic affects the methylation of PTPN6 gene CTD PMID:25304211 arsenic atom decreases expression ISO PTPN6 (Homo sapiens) 6480464 Arsenic results in decreased expression of PTPN6 mRNA CTD PMID:35031324 arsenic atom increases expression ISO PTPN6 (Homo sapiens) 6480464 Arsenic results in increased expression of PTPN6 protein CTD PMID:35031324 arsenous acid multiple interactions ISO PTPN6 (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with Decitabine] results in increased expression of PTPN6 mRNA more ... CTD PMID:19619438 more ... arsenous acid decreases methylation ISO PTPN6 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased methylation of PTPN6 promoter CTD PMID:19950550 arsenous acid increases expression ISO PTPN6 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PTPN6 mRNA and Arsenic Trioxide results in increased expression of PTPN6 protein CTD PMID:19950550 more ... atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of PTPN6 mRNA CTD PMID:36841081 benzo[a]pyrene decreases expression ISO Ptpn6 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PTPN6 mRNA CTD PMID:21569818 benzo[a]pyrene decreases methylation ISO PTPN6 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of PTPN6 promoter CTD PMID:27901495 benzo[a]pyrene affects methylation ISO PTPN6 (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PTPN6 3' UTR and Benzo(a)pyrene affects the methylation of PTPN6 intron CTD PMID:27901495 and PMID:30157460 benzo[a]pyrene increases expression ISO Ptpn6 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of PTPN6 mRNA CTD PMID:22228805 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PTPN6 mRNA CTD PMID:18180321 bisphenol A increases expression ISO Ptpn6 (Mus musculus) 6480464 bisphenol A results in increased expression of PTPN6 mRNA CTD PMID:32156529 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PTPN6 mRNA CTD PMID:30816183 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PTPN6 mRNA CTD PMID:25181051 bortezomib decreases expression ISO PTPN6 (Homo sapiens) 6480464 Bortezomib results in decreased expression of PTPN6 mRNA CTD PMID:17659339 caffeine decreases phosphorylation ISO PTPN6 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of PTPN6 protein CTD PMID:35688186 capillarisin increases expression ISO PTPN6 (Homo sapiens) 6480464 capillarisin results in increased expression of PTPN6 mRNA and capillarisin results in increased expression of PTPN6 protein CTD PMID:24333736 capillarisin multiple interactions ISO PTPN6 (Homo sapiens) 6480464 PTPN6 protein affects the reaction [capillarisin results in decreased phosphorylation of JAK1 protein] more ... CTD PMID:24333736 carbon nanotube increases expression ISO Ptpn6 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 CGP 52608 multiple interactions ISO PTPN6 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to PTPN6 gene] CTD PMID:28238834 chlordecone increases expression ISO Ptpn6 (Mus musculus) 6480464 Chlordecone results in increased expression of PTPN6 mRNA CTD PMID:17578864 chloroprene decreases expression ISO Ptpn6 (Mus musculus) 6480464 Chloroprene results in decreased expression of PTPN6 mRNA CTD PMID:23125180 cisplatin increases expression ISO PTPN6 (Homo sapiens) 6480464 Cisplatin results in increased expression of PTPN6 mRNA CTD PMID:27392435 cisplatin multiple interactions ISO PTPN6 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of PTPN6 mRNA more ... CTD PMID:27392435 clofibrate increases expression ISO Ptpn6 (Mus musculus) 6480464 Clofibrate results in increased expression of PTPN6 mRNA CTD PMID:17585979 copper(II) sulfate decreases expression ISO PTPN6 (Homo sapiens) 6480464 Copper Sulfate results in decreased expression of PTPN6 mRNA CTD PMID:19549813 coumarin increases phosphorylation ISO PTPN6 (Homo sapiens) 6480464 coumarin results in increased phosphorylation of PTPN6 protein CTD PMID:35688186 Cuprizon increases expression EXP 6480464 Cuprizone results in increased expression of PTPN6 mRNA CTD PMID:27523638 curcumin increases expression ISO PTPN6 (Homo sapiens) 6480464 Curcumin results in increased expression of PTPN6 mRNA CTD PMID:17198877 cyclosporin A decreases expression ISO PTPN6 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of PTPN6 mRNA CTD PMID:20106945 and PMID:25224403 cyclosporin A decreases expression ISO Ptpn6 (Mus musculus) 6480464 Cyclosporine results in decreased expression of PTPN6 mRNA CTD PMID:25224403 diarsenic trioxide multiple interactions ISO PTPN6 (Homo sapiens) 6480464 [Arsenic Trioxide co-treated with Decitabine] results in increased expression of PTPN6 mRNA more ... CTD PMID:19619438 more ... diarsenic trioxide decreases methylation ISO PTPN6 (Homo sapiens) 6480464 Arsenic Trioxide results in decreased methylation of PTPN6 promoter CTD PMID:19950550 diarsenic trioxide increases expression ISO PTPN6 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of PTPN6 mRNA and Arsenic Trioxide results in increased expression of PTPN6 protein CTD PMID:19950550 more ... digitoxin increases expression ISO PTPN6 (Homo sapiens) 6480464 Digitoxin results in increased expression of PTPN6 protein CTD PMID:34717917 diuron decreases expression ISO PTPN6 (Homo sapiens) 6480464 Diuron results in decreased expression of PTPN6 mRNA CTD PMID:35967413 elemental selenium multiple interactions ISO PTPN6 (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in increased expression of PTPN6 mRNA CTD PMID:19244175 elemental selenium increases expression ISO PTPN6 (Homo sapiens) 6480464 Selenium results in increased expression of PTPN6 mRNA CTD PMID:19244175 emodin increases expression ISO PTPN6 (Homo sapiens) 6480464 Emodin results in increased expression of PTPN6 protein CTD PMID:23848338 emodin multiple interactions ISO PTPN6 (Homo sapiens) 6480464 PTPN6 mutant form inhibits the reaction [Emodin results in decreased phosphorylation of and results in decreased activity of STAT3 protein] CTD PMID:23848338 endosulfan increases expression EXP 6480464 Endosulfan results in increased expression of PTPN6 mRNA CTD PMID:29391264 ethanol multiple interactions EXP 6480464 [Fish Oils co-treated with Ethanol] results in increased expression of PTPN6 mRNA CTD PMID:17347304 ethanol increases expression ISO Ptpn6 (Mus musculus) 6480464 Ethanol results in increased expression of PTPN6 mRNA CTD PMID:30319688 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of PTPN6 mRNA CTD PMID:18035473 fonofos increases methylation ISO PTPN6 (Homo sapiens) 6480464 Fonofos results in increased methylation of PTPN6 promoter CTD PMID:22847954 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of PTPN6 mRNA CTD PMID:22061828 hydrogen peroxide affects expression ISO PTPN6 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of PTPN6 mRNA CTD PMID:20044591 hydrogen peroxide decreases response to substance ISO Ptpn6 (Mus musculus) 6480464 PTPN6 protein results in decreased susceptibility to Hydrogen Peroxide CTD PMID:18441283 hydrogen peroxide multiple interactions ISO Ptpn6 (Mus musculus) 6480464 PTPN6 protein inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of NFKBIA protein] and PTPN6 protein inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of STAT6 protein] CTD PMID:18441283 hydrogen peroxide multiple interactions ISO PTPN6 (Homo sapiens) 6480464 PTPN6 protein inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL20 protein] and PTPN6 protein inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL5 protein] CTD PMID:18441283 lead diacetate decreases expression ISO Ptpn6 (Mus musculus) 6480464 lead acetate results in decreased expression of PTPN6 mRNA CTD PMID:22609695 lidocaine increases expression EXP 6480464 Lidocaine results in increased expression of PTPN6 mRNA CTD PMID:35283115 lipopolysaccharide multiple interactions ISO Ptpn6 (Mus musculus) 6480464 [[PTPN6 protein results in increased phosphorylation of MAPK1 protein] which results in increased activity of CEBPB protein] promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein] more ... CTD PMID:21422245 methoxyacetic acid affects expression EXP 6480464 methoxyacetic acid affects the expression of PTPN6 mRNA CTD PMID:20864626 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of PTPN6 gene CTD PMID:23303685 nickel atom increases expression ISO PTPN6 (Homo sapiens) 6480464 Nickel results in increased expression of PTPN6 mRNA CTD PMID:25583101 nickel sulfate increases expression ISO PTPN6 (Homo sapiens) 6480464 nickel sulfate results in increased expression of PTPN6 mRNA CTD PMID:22714537 paracetamol decreases expression ISO PTPN6 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of PTPN6 mRNA CTD PMID:29067470 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of PTPN6 mRNA CTD PMID:33387578 paraquat multiple interactions ISO Ptpn6 (Mus musculus) 6480464 PTPN6 protein inhibits the reaction [Paraquat results in decreased expression of IL10 protein] and PTPN6 protein inhibits the reaction [Paraquat results in increased expression of CCL20 protein] CTD PMID:18441283 parathion increases methylation ISO PTPN6 (Homo sapiens) 6480464 Parathion results in increased methylation of PTPN6 promoter CTD PMID:22847954 PD123319 multiple interactions EXP 6480464 PD 123319 affects the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]] CTD PMID:17068200 pirinixic acid increases expression ISO Ptpn6 (Mus musculus) 6480464 pirinixic acid results in increased expression of PTPN6 mRNA CTD PMID:18301758 more ... potassium dichromate decreases expression ISO Ptpn6 (Mus musculus) 6480464 Potassium Dichromate results in decreased expression of PTPN6 mRNA CTD PMID:23608068 raloxifene decreases activity ISO PTPN6 (Homo sapiens) 6480464 Raloxifene Hydrochloride results in decreased activity of PTPN6 protein CTD PMID:17272397 rotenone decreases expression ISO PTPN6 (Homo sapiens) 6480464 Rotenone results in decreased expression of PTPN6 mRNA CTD PMID:33512557 selenium atom multiple interactions ISO PTPN6 (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in increased expression of PTPN6 mRNA CTD PMID:19244175 selenium atom increases expression ISO PTPN6 (Homo sapiens) 6480464 Selenium results in increased expression of PTPN6 mRNA CTD PMID:19244175 silicon dioxide decreases expression ISO PTPN6 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of PTPN6 mRNA CTD PMID:25895662 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of PTPN6 mRNA CTD PMID:32721576 silver atom increases expression ISO Ptpn6 (Mus musculus) 6480464 Silver results in increased expression of PTPN6 mRNA CTD PMID:27131904 silver(0) increases expression ISO Ptpn6 (Mus musculus) 6480464 Silver results in increased expression of PTPN6 mRNA CTD PMID:27131904 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of PTPN6 protein CTD PMID:19072884 sodium chloride decreases expression ISO PTPN6 (Homo sapiens) 6480464 Sodium Chloride results in decreased expression of PTPN6 mRNA CTD PMID:23634900 sodium stibogluconate decreases activity ISO PTPN6 (Homo sapiens) 6480464 Antimony Sodium Gluconate results in decreased activity of PTPN6 protein CTD PMID:12399974 Soman increases expression EXP 6480464 Soman results in increased expression of PTPN6 mRNA CTD PMID:19281266 terbufos increases methylation ISO PTPN6 (Homo sapiens) 6480464 terbufos results in increased methylation of PTPN6 promoter CTD PMID:22847954 tetrachloromethane decreases expression ISO Ptpn6 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of PTPN6 mRNA CTD PMID:31919559 tetraphene increases expression ISO Ptpn6 (Mus musculus) 6480464 benz(a)anthracene results in increased expression of PTPN6 mRNA CTD PMID:26377693 thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of PTPN6 protein CTD PMID:35544339 titanium dioxide increases expression ISO Ptpn6 (Mus musculus) 6480464 titanium dioxide results in increased expression of PTPN6 mRNA CTD PMID:23557971 Tributyltin oxide increases phosphorylation ISO Ptpn6 (Mus musculus) 6480464 bis(tri-n-butyltin)oxide results in increased phosphorylation of PTPN6 protein CTD PMID:22174045 Tributyltin oxide increases expression EXP 6480464 bis(tri-n-butyltin)oxide results in increased expression of PTPN6 mRNA CTD PMID:17553608 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of PTPN6 mRNA CTD PMID:33387578 trimethyltin increases expression ISO Ptpn6 (Mus musculus) 6480464 trimethyltin results in increased expression of PTPN6 mRNA CTD PMID:20833246 valproic acid increases methylation ISO PTPN6 (Homo sapiens) 6480464 Valproic Acid results in increased methylation of PTPN6 gene CTD PMID:29154799 valproic acid decreases expression ISO PTPN6 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of PTPN6 mRNA CTD PMID:29154799 valproic acid increases expression ISO PTPN6 (Homo sapiens) 6480464 Valproic Acid results in increased expression of PTPN6 mRNA CTD PMID:23527032 valsartan multiple interactions EXP 6480464 Valsartan promotes the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]] CTD PMID:17068200 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of PTPN6 mRNA CTD PMID:20566332 vitamin E increases expression ISO PTPN6 (Homo sapiens) 6480464 Vitamin E results in increased expression of PTPN6 mRNA CTD PMID:19244175 vitamin E multiple interactions ISO PTPN6 (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in increased expression of PTPN6 mRNA CTD PMID:19244175