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Gene: C1r (complement C1r) Rattus norvegicus
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Symbol: C1r
Name: complement C1r
Description: Predicted to have calcium ion binding activity and serine-type endopeptidase activity. Predicted to be involved in zymogen activation. Predicted to localize to the extracellular space. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome. Orthologous to human C1R (complement C1r); PARTICIPATES IN coagulation cascade pathway; complement system pathway; phagocytosis pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: complement C1r subcomponent; complement component 1, r subcomponent; LOC312705
Orthologs:
Homo sapiens (human) : C1R (complement C1r)  HGNC  Alliance
Mus musculus (house mouse) : C1rb (complement component 1, r subcomponent B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C1r (complement C1r)
Pan paniscus (bonobo/pygmy chimpanzee) : C1R (complement C1r)
Canis lupus familiaris (dog) : C1R (complement C1r)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C1r (complement C1r)
Sus scrofa (pig) : C1R (complement C1r)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04157,126,060 - 157,136,825 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,144,564 - 224,155,329 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,712,582 - 160,729,362 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14160,957,464 - 160,974,090 (+)NCBI
Celera4146,152,622 - 146,163,370 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on C1r
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309091
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.