Etv2 (ETS variant transcription factor 2)

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Gene: Etv2 (ETS variant transcription factor 2) Rattus norvegicus

Analyze

Symbol:

Etv2

Name:

ETS variant transcription factor 2

RGD ID:

1310603

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including cell surface receptor signaling pathway; positive regulation of endothelial cell differentiation; and positive regulation of macromolecule metabolic process. Predicted to be active in nucleus. Orthologous to human ETV2 (ETS variant transcription factor 2); INTERACTS WITH bisphenol A; Monobutylphthalate; N-methyl-4-phenylpyridinium.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ets related protein 71; ETS translocation variant 2; ets variant 2; ets variant gene 2; Etsrp71; LOC361544

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ETV2 (ETS variant transcription factor 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Etv2 (ets variant 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Etv2 (ETS variant transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ETV2 (ETS variant transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ETV2 (ETS variant transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Etv2 (ETS variant transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ETV2 (ETS variant transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ETV2 (ETS variant transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Etv2 (ETS variant transcription factor 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ETV2 (ETS variant transcription factor 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Etv2 (ets variant 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ast-1	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	85,890,559 - 85,893,431 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	89,091,239 - 89,094,570 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	89,091,239 - 89,094,530 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	90,246,861 - 90,250,074 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	85,684,698 - 85,686,914 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	85,762,809 - 85,765,732 (-)	NCBI
Celera	1	80,262,333 - 80,264,853 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Aortic Remodeling (ISO)

Brugada syndrome 5 (ISO)

dystonia (ISO)

genetic disease (ISO)

hereditary spastic paraplegia 75 (ISO)

limb ischemia (ISO)

polydactyly (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

5-fluorouracil (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

copper(II) sulfate (ISO)

digitonin (ISO)

mercury dichloride (ISO)

Monobutylphthalate (EXP)

N-methyl-4-phenylpyridinium (EXP)

nickel sulfate (ISO)

PCB138 (EXP)

resveratrol (ISO)

silver atom (ISO)

silver(0) (ISO)

sotorasib (ISO)

trametinib (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blastocyst development (ISO)

blood vessel morphogenesis (ISO)

BMP signaling pathway involved in mesodermal cell fate specification (ISO)

erythrocyte differentiation (ISO)

hemopoiesis (ISO)

in utero embryonic development (ISO)

mesoderm formation (ISO)

Notch signaling pathway (ISO)

placenta development (ISO)

positive regulation of endothelial cell differentiation (ISO)

positive regulation of gene expression (ISO)

positive regulation of mesoderm development (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of transcription by RNA polymerase II (IBA)

Wnt signaling pathway (ISO)

Cellular Component

nucleus (IBA)

Molecular Function

DNA-binding transcription activator activity, RNA polymerase II-specific (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Adventitial Sca1+ Cells Transduced With ETV2 Are Committed to the Endothelial Fate and Improve Vascular Remodeling After Injury.	Le Bras A, etal., Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):232-244. doi: 10.1161/ATVBAHA.117.309853. Epub 2017 Nov 30.
3.	Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2.	Park C, etal., Arterioscler Thromb Vasc Biol. 2016 Jan;36(1):86-96. doi: 10.1161/ATVBAHA.115.306430. Epub 2015 Nov 19.
4.	Etv2- and Fli1-Induced Vascular Progenitor Cells Enhance Functional Recovery in Ischemic Vascular Disease Model-Brief Report.	Park SY, etal., Arterioscler Thromb Vasc Biol. 2020 Apr;40(4):e105-e113. doi: 10.1161/ATVBAHA.119.313684. Epub 2020 Feb 20.
5.	GOA pipeline	RGD automated data pipeline
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Extracellular vesicles of ETV2 transfected fibroblasts stimulate endothelial cells and improve neovascularization in a murine model of hindlimb ischemia.	Van Pham P, etal., Cytotechnology. 2017 Oct;69(5):801-814. doi: 10.1007/s10616-017-0095-2. Epub 2017 May 2.
8.	ETV-2 activated proliferation of endothelial cells and attenuated acute hindlimb ischemia in mice.	Van Pham P, etal., In Vitro Cell Dev Biol Anim. 2017 Aug;53(7):616-625. doi: 10.1007/s11626-017-0151-4. Epub 2017 Apr 19.

Additional References at PubMed

PMID:12087183	PMID:16630543	PMID:18462699

Genomics

Comparative Map Data

Etv2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	85,890,559 - 85,893,431 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	1	89,091,239 - 89,094,570 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	89,091,239 - 89,094,530 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	90,246,861 - 90,250,074 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	85,684,698 - 85,686,914 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	1	85,762,809 - 85,765,732 (-)	NCBI
Celera	1	80,262,333 - 80,264,853 (-)	NCBI		Celera
Cytogenetic Map	1	q21	NCBI

ETV2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	35,641,745 - 35,644,871 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	19	35,641,745 - 35,644,871 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	36,132,647 - 36,135,773 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	40,824,487 - 40,827,613 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	19	32,846,129 - 32,849,256 (+)	NCBI		Celera
Cytogenetic Map	19	q13.12	NCBI
HuRef	19	32,637,910 - 32,641,036 (+)	NCBI		HuRef
CHM1_1	19	36,134,179 - 36,137,305 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	38,186,718 - 38,189,844 (+)	NCBI		T2T-CHM13v2.0

Etv2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	30,333,041 - 30,335,934 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	30,333,041 - 30,335,277 (-)	Ensembl		GRCm39 Ensembl
GRCm38	7	30,633,616 - 30,636,509 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	30,633,616 - 30,635,852 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	31,418,635 - 31,420,871 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	30,342,378 - 30,344,612 (-)	NCBI		MGSCv36	mm8
Celera	7	25,225,816 - 25,227,677 (-)	NCBI		Celera
Cytogenetic Map	7	B1	NCBI

Etv2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	4,857,595 - 4,860,531 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	4,857,023 - 4,859,926 (+)	NCBI	ChiLan1.0	ChiLan1.0

ETV2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	41,307,864 - 41,311,004 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	41,307,864 - 41,311,004 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	32,571,829 - 32,575,083 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

ETV2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	116,971,238 - 116,974,831 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	116,971,365 - 116,985,796 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	116,376,575 - 116,379,674 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	1	117,574,597 - 117,577,707 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	1	117,574,598 - 117,577,031 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	1	117,137,602 - 117,140,703 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	1	116,761,500 - 116,764,598 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	1	117,817,402 - 117,820,510 (-)	NCBI		UU_Cfam_GSD_1.0

Etv2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	10,971,607 - 10,974,730 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936570	671,152 - 673,768 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ETV2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	45,087,100 - 45,089,626 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	45,085,984 - 45,089,592 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	40,543,308 - 40,546,424 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ETV2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	30,552,780 - 30,556,374 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	30,553,931 - 30,556,355 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666073	8,348,216 - 8,351,726 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Etv2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	7,984,884 - 7,988,296 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	7,985,662 - 7,989,063 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Etv2
16 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	32
Count of miRNA genes:	32
Interacting mature miRNAs:	32
Transcripts:	ENSRNOT00000031873
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	509108	86060548	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5925874	115540829	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	22340647	102268831	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	30882023	123479925	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	32737273	90665040	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43284731	118944897	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43284731	118944897	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43284731	118944897	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43284731	118944897	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	compact volumetric bone mineral density (CMO:0001730)	1	43284731	118944897	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43284731	118944897	Rat
2302059	Pia36	Pristane induced arthritis QTL 36	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	43333002	88333002	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	48963584	144267916	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49393172	94393172	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	53863041	90532583	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	56732668	98773277	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	56949932	101949932	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
1300121	Hrtrt1	Heart rate QTL 1	3.7		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	65789093	115540829	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	66023617	118608521	Rat
631512	Scl6	Serum cholesterol level QTL 6	9.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	1	72197680	90508767	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	77494165	122494165	Rat
10054135	Gmadr2	Adrenal mass QTL 2	1.97	0.0129	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	77857876	122857876	Rat
1549903	Bp267	Blood pressure QTL 267			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	77876254	106047988	Rat
61344	Bp29	Blood pressure QTL 29	7.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	78350581	123350581	Rat
7411712	Strs4	Sensitivity to stroke QTL 4	8.7		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	1	78430536	123430536	Rat
61433	Cia2	Collagen induced arthritis QTL 2	5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	78430754	91209302	Rat
1582234	Gluco18	Glucose level QTL 18	3.4	0.0003	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	78479925	123479925	Rat
4889494	Scort2	Serum corticosterone level QTL 2	4.2		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	80592172	125592172	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
2313083	Bmd74	Bone mineral density QTL 74	4	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	82174743	118944897	Rat
738022	Anxrr13	Anxiety related response QTL 13	4.6	0.00039	locomotor behavior trait (VT:0001392)	number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)	1	83547917	128547917	Rat
2300324	Fetw1	Fetal weight QTL 1	12.1	0.005	fetal growth trait (VT:0004201)	fetal body weight (CMO:0002080)	1	85424647	100358001	Rat

Markers in Region

BE102623

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	85,890,596 - 85,890,749 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	89,091,275 - 89,091,427	NCBI	Rnor6.0
Rnor_5.0	1	90,246,892 - 90,247,044	UniSTS	Rnor5.0
RGSC_v3.4	1	85,684,733 - 85,684,885	UniSTS	RGSC3.4
Celera	1	80,262,369 - 80,262,521	UniSTS
RH 3.4 Map	1	851.7	UniSTS
Cytogenetic Map	1	q21	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	circulatory system	endocrine system	exocrine system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	reproductive system	respiratory system	appendage
High
Medium								2
Low	6							10
Below cutoff	4	4	4	4	1	1	24	9	1	1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_006223194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006223195	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228814	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228815	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590044	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590045	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017591193	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093961	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC141526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473979	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000033	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000031873 ⟹ ENSRNOP00000036461

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	85,890,559 - 85,893,431 (-)	Ensembl
Rnor_6.0 Ensembl	1	89,091,239 - 89,094,530 (-)	Ensembl

RefSeq Acc Id:

XM_006228814 ⟹ XP_006228876

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI
Rnor_6.0	1	89,091,239 - 89,094,570 (-)	NCBI
Rnor_5.0	1	90,246,861 - 90,250,074 (-)	NCBI

Sequence:

show sequence

ACCTATCACTGCCGCACATAAAATTATTCCACGCAATAATTCACATTCAGTTCATACTCAAAAA
TCCCCAGTTGTTTGCGACTGCTATAGCTCAGAAAGCCCAGACAGAAAAAGCATGCCTCAGTTTC
CCCCTTCATAAACTTGGGATAAAAACATTTCCCCCTTGAGAAGATTAAATGAAAGTCCGTTTTT
GTGTATGGCTTCTCGGACCGGCAGACGCTCATTTAACGTTAGTGGTTTCTATTACTATTATTAT
CGCCCATGATGATGTTATTTTGATTATGATTGCCATTATTCGATAGTAATTCCAGGACACCCTC
CCTCTGCCTGGTAAGGGATTCAGGGTTGGATTCCCCCACCCCACTCCATCTGGCTGTCTGTCAC
CCTGCCGATTGTGACGTAGGCTGATGCTAGGGAAAGGGGGCATCTGGCCGGAAATCCCTCTTCC
TGTTGCAGATAAGCCCAGAGTTGCCCAGCTGACCCCAGACCCTCCTCCCCCACCGCTTTTCATG
TCTCACCACCAAATCCTCAAGACGGGGAACCTGTCCAAACCCCTCACCCCATCCCCACTACCCC
GTAAGCACCCCTTAGATCTCAGTACCCCCATCCCTGCCTTACCCTTGTTCCCCAAGTCCTTTTC
CAAGCCCAATTTGTCCCTGCAAAAGGACCGTTCCAGGGACCAATGCGCATCCCTAAAGCAGGGG
GTGCAACTTGACCACGCCCCCATCCCTGCAACTTGACCCAGGCTGCGACCCCCAGCTCTGACGT
CTCGGAAAATTCCCCCTCCCCTATCAGGCCCCCCGGGAAGGGTGCATGGTATGAAATGGGGCTG
AGACCCCCCCTGGCAAGGAGAGAAGGAACCTGCCAGAGAACCGTCAGAACAAGCCTCCATGGAC
CTGTGGAACTGGGATGAAGCGTCAGTGCAGGAAGTACCTCCTGGAGACAAGCTGACAGGACTGG
AAGGAGCGGAATTTGGTTTCTATTTCCCTGAAGTGGCACTGCAAGGGGACACACCGATCACACC
GATGAACGTAGAAAGCTGCTGGAAAGGGTTCCCAGAGCTGGACTGGAACCCCGCTTTACCTCAC
GAAGAAGTACCTTTCGAGGCCGAGCCCGTTGCTCACCCCCTTCCGTGGTCGCGAGACTGGACAG
ACCTGGGGTGCAACACCTCGGACCCGTGGAGCTGTGCTTCGCAGACGCCAGGCCCCGCCCCTCC
GGGCACGAGCCCCTCCCCCTTCGTCGGCTTTGAAGGGGCGACCGGCCAGAATACTGCCACCTCG
GCAGGAGGGGTCCCCTCGTGGTCGCACCCTCCCGCCACCTGGAGCACCGCCAGCTGGGACTGTT
CTGCGGGCCCCAATGGATCCACCTACTGGGACAGTGGCCTGGGCGGGGAAGCGCAGGCGGACTA
TAAAATGTCGTGGGGCGGGTCTGCGGGTTCGGACTACACCACCACGTGGAATAGTGGGCTGCAA
AACTGCAGCATCCCTTTCGAGGGGCACCAGATTCCAGCATTCGCCACGCCATCCAAATCGAGCC
AGCAGTCTGATCGAGCCACATTGACTCCCTACTCCAAAACTAACCACCGAGGTCCCATTCAGTT
GTGGCAGTTCCTCCTGGAGCTGCTCCACGACGGGGCGCGCAGCAGCTGCATCCGCTGGACCGGC
AATAACCGCGAGTTCCAGCTGTGCGACCCCAAAGAGGTAGCCCGGCTGTGGGGCGAGCGCAAGA
GGAAGCCGGGAATGAATTATGAGAAGCTGAGCCGAGGTCTACGTTACTATTACCGCCGCGACAT
CGTGCTCAAGAGCGGTGGGCGCAAGTACACATACCGCTTCGGGGGACGCGTGCCTGTCCTTGCC
TGTCAGGATGATATGGGACATCTGCCGGGTGCAGAAGGCCAATAAAAGAAAAAACAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006228815 ⟹ XP_006228877

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI
Rnor_6.0	1	89,091,239 - 89,094,570 (-)	NCBI
Rnor_5.0	1	90,246,861 - 90,250,074 (-)	NCBI

Sequence:

show sequence

ACCTATCACTGCCGCACATAAAATTATTCCACGCAATAATTCACATTCAGTTCATACTCAAAAA
TCCCCAGTTGTTTGCGACTGCTATAGCTCAGAAAGCCCAGACAGAAAAAGCATGCCTCAGTTTC
CCCCTTCATAAACTTGGGATAAAAACATTTCCCCCTTGAGAAGATTAAATGAAAGTCCGTTTTT
GTGTATGGCTTCTCGGACCGGCAGACGCTCATTTAACGTTAGTGGTTTCTATTACTATTATTAT
CGCCCATGATGATGTTATTTTGATTATGATTGCCATTATTCGATAGTAATTCCAGGACACCCTC
CCTCTGCCTGGTAAGGGATTCAGGGTTGGATTCCCCCACCCCACTCCATCTGGCTGTCTGTCAC
CCTGCCGATTGTGACGTAGGCTGATGCTAGGGAAAGGGGGCATCTGGCCGGAAATCCCTCTTCC
TGTTGCAGATAAGCCCAGAGTTGCCCAGCTGACCCCAGACCCTCCTCCCCCACCGCTTTTCATG
TCTCACCACCAAATCCTCAAGACGGGGAACCTGTCCAAACCCCTCACCCCATCCCCACTACCCC
GTAAGCACCCCTTAGATCTCAGTACCCCCATCCCTGCCTTACCCTTGTTCCCCAAGTCCTTTTC
CAAGCCCAATTTGTCCCTGCAAAAGGACCGTTCCAGGGACCAATGCGCATCCCTAAAGCAGGGG
GTGCAACTTGACCACGCCCCCATCCCTGCAACTTGACCCAGGCTGCGACCCCCAGCTCTGACGT
CTCGGAAAATTCCCCCTCCCCTATCAGGCCCCCCGGGAAGGGTGCATGGTATGAAATGGGGCTG
AGACCCCCCCTGGCAAGGAGAGAAGGAACCTGCCAGAGTTTTCCTCTCTCAACCAGAACCGTCA
GAACAAGCCTCCATGGACCTGTGGAACTGGGATGAAGCGTCAGTGCAGGAAGTACCTCCTGGAG
ACAAGCTGACAGGACTGGAAGGAGCGGAATTTGGTTTCTATTTCCCTGAAGTGGCACTGCAAGG
GGACACACCGATCACACCGATGAACGTAGAAAGCTGCTGGAAAGGGTTCCCAGAGCTGGACTGG
AACCCCGCTTTACCTCACGAAGAAGTACCTTTCGAGGCCGAGCCCGTTGCTCACCCCCTTCCGT
GGTCGCGAGACTGGACAGACCTGGGGTGCAACACCTCGGACCCGTGGAGCTGTGCTTCGCAGAC
GCCAGGCCCCGCCCCTCCGGGCACGAGCCCCTCCCCCTTCGTCGGCTTTGAAGGGGCGACCGGC
CAGAATACTGCCACCTCGGCAGGAGGGGTCCCCTCGTGGTCGCACCCTCCCGCCACCTGGAGCA
CCGCCAGCTGGGACTGTTCTGCGGGCCCCAATGGATCCACCTACTGGGACAGTGGCCTGGGCGG
GGAAGCGCAGGCGGACTATAAAATGTCGTGGGGCGGGTCTGCGGGTTCGGACTACACCACCACG
TGGAATAGTGGGCTGCAAAACTGCAGCATCCCTTTCGAGGGGCACCAGATTCCAGCATTCGCCA
CGCCATCCAAATCGAGCCAGCAGTCTGATCGAGCCACATTGACTCCCTACTCCAAAACTAACCA
CCGAGGTCCCATTCAGTTGTGGCAGTTCCTCCTGGAGCTGCTCCACGACGGGGCGCGCAGCAGC
TGCATCCGCTGGACCGGCAATAACCGCGAGTTCCAGCTGTGCGACCCCAAAGAGGTAGCCCGGC
TGTGGGGCGAGCGCAAGAGGAAGCCGGGAATGAATTATGAGAAGCTGAGCCGAGGTCTACGTTA
CTATTACCGCCGCGACATCGTGCTCAAGAGCGGTGGGCGCAAGTACACATACCGCTTCGGGGGA
CGCGTGCCTGTCCTTGCCTGTCAGGATGATATGGGACATCTGCCGGGTGCAGAAGGCCAATAAA
AGAAAAAACAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017590045 ⟹ XP_017445534

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI
Rnor_6.0	1	89,091,239 - 89,094,570 (-)	NCBI

Sequence:

show sequence

ACCTATCACTGCCGCACATAAAATTATTCCACGCAATAATTCACATTCAGTTCATACTCAAAAA
TCCCCAGTTGTTTGCGACTGCTATAGCTCAGAAAGCCCAGACAGAAAAAGCATGCCTCAGTTTC
CCCCTTCATAAACTTGGGATAAAAACATTTCCCCCTTGAGAAGATTAAATGAAAGTCCGTTTTT
GTGTATGGCTTCTCGGACCGGCAGACGCTCATTTAACGTTAGTGGTTTCTATTACTATTATTAT
CGCCCATGATGATGTTATTTTGATTATGATTGCCATTATTCGATAGTAATTCCAGGACACCCTC
CCTCTGCCTGGTAAGGGATTCAGGGTTGGATTCCCCCACCCCACTCCATCTGGCTGTCTGTCAC
CCTGCCGATTGTGACGTAGGCTGATGCTAGGGAAAGGGGGCATCTGGCCGGAAATCCCTCTTCC
TGTTGCAGATAAGCCCAGAGTTGCCCAGCTGACCCCAGACCCTCCTCCCCCACCGCTTTTCATG
TCTCACCACCAAATCCTCAAGACGGGGAACCTGTCCAAACCCCTCACCCCATCCCCACTACCCC
GTAAGCACCCCTTAGATCTCAGTACCCCCATCCCTGCCTTACCCTTGTTCCCCAAGTCCTTTTC
CAAGCCCAATTTGTCCCTGCAAAAGGACCGTTCCAGGGACCAATGCGCATCCCTAAAGCAGGGG
GTGCAACTTGACCACGCCCCCATCCCTGCAACTTGACCCAGGCTGCGACCCCCAGCTCTGACGT
CTCGGAAAATTCCCCCTCCCCTATCAGGCCCCCCGGGAAGGGTGCATGGTATGAAATGGGGCTG
AGACCCCCCCTGGCAAGGAGAGAAGGAACCTGCCAGAGAACCGTCAGAACAAGCCTCCATGGAC
CTGTGGAACTGGGATGAAGCGTCAGTGCAGGAAGTACCTCCTGGAGACAAGCTGACAGGACTGG
GAGCGGAATTTGGTTTCTATTTCCCTGAAGTGGCACTGCAAGGGGACACACCGATCACACCGAT
GAACGTAGAAAGCTGCTGGAAAGGGTTCCCAGAGCTGGACTGGAACCCCGCTTTACCTCACGAA
GAAGTACCTTTCGAGGCCGAGCCCGTTGCTCACCCCCTTCCGTGGTCGCGAGACTGGACAGACC
TGGGGTGCAACACCTCGGACCCGTGGAGCTGTGCTTCGCAGACGCCAGGCCCCGCCCCTCCGGG
CACGAGCCCCTCCCCCTTCGTCGGCTTTGAAGGGGCGACCGGCCAGAATACTGCCACCTCGGCA
GGAGGGGTCCCCTCGTGGTCGCACCCTCCCGCCACCTGGAGCACCGCCAGCTGGGACTGTTCTG
CGGGCCCCAATGGATCCACCTACTGGGACAGTGGCCTGGGCGGGGAAGCGCAGGCGGACTATAA
AATGTCGTGGGGCGGGTCTGCGGGTTCGGACTACACCACCACGTGGAATAGTGGGCTGCAAAAC
TGCAGCATCCCTTTCGAGGGGCACCAGATTCCAGCATTCGCCACGCCATCCAAATCGAGCCAGC
AGTCTGATCGAGCCACATTGACTCCCTACTCCAAAACTAACCACCGAGGTCCCATTCAGTTGTG
GCAGTTCCTCCTGGAGCTGCTCCACGACGGGGCGCGCAGCAGCTGCATCCGCTGGACCGGCAAT
AACCGCGAGTTCCAGCTGTGCGACCCCAAAGAGGTAGCCCGGCTGTGGGGCGAGCGCAAGAGGA
AGCCGGGAATGAATTATGAGAAGCTGAGCCGAGGTCTACGTTACTATTACCGCCGCGACATCGT
GCTCAAGAGCGGTGGGCGCAAGTACACATACCGCTTCGGGGGACGCGTGCCTGTCCTTGCCTGT
CAGGATGATATGGGACATCTGCCGGGTGCAGAAGGCCAATAAAAGAAAAAACAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039093958 ⟹ XP_038949886

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI

RefSeq Acc Id:

XM_039093960 ⟹ XP_038949888

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI

RefSeq Acc Id:

XM_039093961 ⟹ XP_038949889

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI

RefSeq Acc Id:

XM_039093962 ⟹ XP_038949890

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI

RefSeq Acc Id:

XM_039093973 ⟹ XP_038949901

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	85,890,562 - 85,894,025 (-)	NCBI

RefSeq Acc Id:

XM_039093974 ⟹ XP_038949902

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	85,890,619 - 85,894,025 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_006228876	(Get FASTA)	NCBI Sequence Viewer
	XP_006228877	(Get FASTA)	NCBI Sequence Viewer
	XP_017445534	(Get FASTA)	NCBI Sequence Viewer
	XP_038949886	(Get FASTA)	NCBI Sequence Viewer
	XP_038949888	(Get FASTA)	NCBI Sequence Viewer
	XP_038949889	(Get FASTA)	NCBI Sequence Viewer
	XP_038949890	(Get FASTA)	NCBI Sequence Viewer
	XP_038949901	(Get FASTA)	NCBI Sequence Viewer
	XP_038949902	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM07729	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	XP_006228876 ⟸ XM_006228814
- Peptide Label:	isoform X2
- UniProtKB:	D3ZEY9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDLWNWDEASVQEVPPGDKLTGLEGAEFGFYFPEVALQGDTPITPMNVESCWKGFPELDWNPAL PHEEVPFEAEPVAHPLPWSRDWTDLGCNTSDPWSCASQTPGPAPPGTSPSPFVGFEGATGQNTA TSAGGVPSWSHPPATWSTASWDCSAGPNGSTYWDSGLGGEAQADYKMSWGGSAGSDYTTTWNSG LQNCSIPFEGHQIPAFATPSKSSQQSDRATLTPYSKTNHRGPIQLWQFLLELLHDGARSSCIRW TGNNREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSGGRKYTYRFGGRVPV LACQDDMGHLPGAEGQ hide sequence

RefSeq Acc Id:	XP_006228877 ⟸ XM_006228815
- Peptide Label:	isoform X2
- UniProtKB:	D3ZEY9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDLWNWDEASVQEVPPGDKLTGLEGAEFGFYFPEVALQGDTPITPMNVESCWKGFPELDWNPAL PHEEVPFEAEPVAHPLPWSRDWTDLGCNTSDPWSCASQTPGPAPPGTSPSPFVGFEGATGQNTA TSAGGVPSWSHPPATWSTASWDCSAGPNGSTYWDSGLGGEAQADYKMSWGGSAGSDYTTTWNSG LQNCSIPFEGHQIPAFATPSKSSQQSDRATLTPYSKTNHRGPIQLWQFLLELLHDGARSSCIRW TGNNREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSGGRKYTYRFGGRVPV LACQDDMGHLPGAEGQ hide sequence

RefSeq Acc Id:

XP_017445534 ⟸ XM_017590045

- Peptide Label:

isoform X3

- Sequence:

show sequence

MDLWNWDEASVQEVPPGDKLTGLGAEFGFYFPEVALQGDTPITPMNVESCWKGFPELDWNPALP
HEEVPFEAEPVAHPLPWSRDWTDLGCNTSDPWSCASQTPGPAPPGTSPSPFVGFEGATGQNTAT
SAGGVPSWSHPPATWSTASWDCSAGPNGSTYWDSGLGGEAQADYKMSWGGSAGSDYTTTWNSGL
QNCSIPFEGHQIPAFATPSKSSQQSDRATLTPYSKTNHRGPIQLWQFLLELLHDGARSSCIRWT
GNNREFQLCDPKEVARLWGERKRKPGMNYEKLSRGLRYYYRRDIVLKSGGRKYTYRFGGRVPVL
ACQDDMGHLPGAEGQ

hide sequence

RefSeq Acc Id:

ENSRNOP00000036461 ⟸ ENSRNOT00000031873

RefSeq Acc Id:	XP_038949889 ⟸ XM_039093961
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038949890 ⟸ XM_039093962
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038949886 ⟸ XM_039093958
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038949901 ⟸ XM_039093973
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038949888 ⟸ XM_039093960
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038949902 ⟸ XM_039093974
- Peptide Label:	isoform X4

Protein Domains

ETS

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZEY9-F1-model_v2	AlphaFold	D3ZEY9	1-336	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310603	AgrOrtholog
BioCyc Gene	G2FUF-60088	BioCyc
Ensembl Genes	ENSRNOG00000024288	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000036461	ENTREZGENE
	ENSRNOP00000036461.6	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000031873	ENTREZGENE
	ENSRNOT00000031873.7	UniProtKB/TrEMBL
Gene3D-CATH	1.10.10.10	UniProtKB/TrEMBL
InterPro	Ets	UniProtKB/TrEMBL
	ETS_fam	UniProtKB/TrEMBL
	WH-like_DNA-bd_sf	UniProtKB/TrEMBL
	WH_DNA-bd_sf	UniProtKB/TrEMBL
KEGG Report	rno:361544	UniProtKB/TrEMBL
NCBI Gene	361544	ENTREZGENE
PANTHER	ETS TRANSLOCATION VARIANT 2	UniProtKB/TrEMBL
	PTHR11849	UniProtKB/TrEMBL
Pfam	Ets	UniProtKB/TrEMBL
PhenoGen	Etv2	PhenoGen
PRINTS	ETSDOMAIN	UniProtKB/TrEMBL
PROSITE	ETS_DOMAIN_1	UniProtKB/TrEMBL
	ETS_DOMAIN_2	UniProtKB/TrEMBL
	ETS_DOMAIN_3	UniProtKB/TrEMBL
SMART	ETS	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46785	UniProtKB/TrEMBL
UniProt	D3ZEY9	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-09-20	Etv2	ETS variant transcription factor 2	Etv2	ets variant 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-10-23	Etv2	ets variant 2	Etv2	ets variant gene 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-04	Etv2	ets variant gene 2	Etsrp71_predicted	ets related protein 71 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Etsrp71_predicted	ets related protein 71 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar