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Gene: Sts (steroid sulfatase) Rattus norvegicus
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Symbol: Sts
Name: steroid sulfatase
Description: Exhibits steryl-sulfatase activity. Involved in several processes, including response to estrogen; response to pH; and skin development. Localizes to the endoplasmic reticulum membrane; integral component of membrane; and nuclear envelope. Biomarker of cryptorchidism and hypertension. Human ortholog(s) of this gene implicated in X-linked ichthyosis. Orthologous to human STS (steroid sulfatase); PARTICIPATES IN estradiol biosynthetic pathway; testosterone biosynthetic pathway; steroid hormone biosynthetic pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,6-dinitrotoluene; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: arylsulfatase C; ASC; steroid sulfatase (microsomal), isozyme S; steryl-sulfatase; steryl-sulfate sulfohydrolase
Orthologs:
Homo sapiens (human) : STS (steroid sulfatase)  HGNC  Alliance
Mus musculus (house mouse) : Sts (steroid sulfatase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sts (steroid sulfatase)
Pan paniscus (bonobo/pygmy chimpanzee) : STS (steroid sulfatase)
Canis lupus familiaris (dog) : STS (steroid sulfatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sts (steroid sulfatase)
Sus scrofa (pig) : STS (steroid sulfatase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X45,420,418 - 45,428,748 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX45,420,596 - 45,428,750 (+)Ensembl
Rnor_5.0X45,646,021 - 45,654,127 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X63,915,803 - 63,923,834 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X63,969,271 - 63,977,302 (+)NCBI
CeleraX42,864,036 - 42,872,067 (+)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sts
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3783
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.