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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mgarp | Rat | (-)-alpha-phellandrene | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of MGARP mRNA | CTD | PMID:25075043 | Mgarp | Rat | (-)-demecolcine | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | Demecolcine results in increased expression of MGARP mRNA | CTD | PMID:23649840 | Mgarp | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MGARP mRNA | CTD | PMID:22079256 | Mgarp | Rat | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in decreased expression of MGARP mRNA | CTD | PMID:27840820 | Mgarp | Rat | 17beta-estradiol | increases expression | ISO | Mgarp (Mus musculus) | 6480464 | Estradiol results in increased expression of MGARP mRNA | CTD | PMID:19484750 | Mgarp | Rat | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of MGARP mRNA | CTD | PMID:32145629 | Mgarp | Rat | 17beta-estradiol | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of MGARP mRNA | CTD | PMID:30165855 | Mgarp | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of MGARP mRNA | CTD | PMID:22298810 | Mgarp | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MGARP mRNA | CTD | PMID:21215274 and PMID:21724226 | Mgarp | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Mgarp (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:38648751 | Mgarp | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MGARP mRNA | CTD | PMID:28628672 | Mgarp | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of MGARP gene | CTD | PMID:31601247 | Mgarp | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of MGARP mRNA | CTD | PMID:24780913 | Mgarp | Rat | 7,12-dimethyltetraphene | increases expression | EXP | | 6480464 | 9 more ... | CTD | PMID:19480007 | Mgarp | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of MGARP mRNA | CTD | PMID:31881176 | Mgarp | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of MGARP mRNA | CTD | PMID:28959563 | Mgarp | Rat | aflatoxin B1 | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of MGARP mRNA | CTD | PMID:27153756 | Mgarp | Rat | all-trans-retinoic acid | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | Tretinoin results in increased expression of MGARP mRNA | CTD | PMID:21934132 and PMID:23724009 | Mgarp | Rat | alpha-phellandrene | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | alpha phellandrene results in increased expression of MGARP mRNA | CTD | PMID:25075043 | Mgarp | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of MGARP mRNA | CTD | PMID:35163327 | Mgarp | Rat | aristolochic acid A | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of MGARP mRNA | CTD | PMID:33212167 | Mgarp | Rat | arsane | affects methylation | ISO | MGARP (Homo sapiens) | 6480464 | Arsenic affects the methylation of MGARP gene | CTD | PMID:25304211 | Mgarp | Rat | arsane | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of MGARP mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of MGARP mRNA | CTD | PMID:39836092 | Mgarp | Rat | arsenic atom | affects methylation | ISO | MGARP (Homo sapiens) | 6480464 | Arsenic affects the methylation of MGARP gene | CTD | PMID:25304211 | Mgarp | Rat | arsenic atom | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of MGARP mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of MGARP mRNA | CTD | PMID:39836092 | Mgarp | Rat | benzo[a]pyrene | affects methylation | ISO | MGARP (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MGARP promoter | CTD | PMID:27901495 | Mgarp | Rat | benzo[a]pyrene | decreases methylation | ISO | MGARP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of MGARP 5' UTR and Benzo(a)pyrene results in decreased methylation of MGARP exon | CTD | PMID:27901495 | Mgarp | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Mgarp (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of MGARP mRNA | CTD | PMID:34319233 | Mgarp | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of MGARP mRNA | CTD | PMID:25181051 and PMID:32145629 | Mgarp | Rat | bisphenol A | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | bisphenol A results in increased expression of MGARP mRNA | CTD | PMID:31715268 | Mgarp | Rat | bisphenol A | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MGARP mRNA | CTD | PMID:28628672 | Mgarp | Rat | butan-1-ol | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of MGARP mRNA | CTD | PMID:29432896 | Mgarp | Rat | butanal | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of MGARP mRNA | CTD | PMID:26079696 | Mgarp | Rat | chromium(6+) | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | chromium hexavalent ion results in decreased expression of MGARP mRNA | CTD | PMID:30690063 | Mgarp | Rat | cisplatin | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | Cisplatin results in increased expression of MGARP mRNA | CTD | PMID:27392435 | Mgarp | Rat | cobalt dichloride | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of MGARP mRNA | CTD | PMID:19320972 | Mgarp | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of MGARP mRNA | CTD | PMID:24386269 | Mgarp | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of MGARP mRNA | CTD | PMID:26577399 and PMID:27523638 | Mgarp | Rat | cyclosporin A | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of MGARP mRNA | CTD | PMID:27989131 | Mgarp | Rat | cytarabine | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | Cytarabine results in decreased expression of MGARP mRNA | CTD | PMID:21198554 | Mgarp | Rat | decabromodiphenyl ether | increases expression | EXP | | 6480464 | decabromobiphenyl ether results in increased expression of MGARP mRNA | CTD | PMID:23914054 | Mgarp | Rat | dexamethasone | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MGARP mRNA | CTD | PMID:28628672 | Mgarp | Rat | dibutyl phthalate | increases methylation | ISO | Mgarp (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased methylation of MGARP gene | CTD | PMID:36602389 | Mgarp | Rat | dibutyl phthalate | decreases expression | ISO | Mgarp (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of MGARP protein | CTD | PMID:36602389 | Mgarp | Rat | dioxygen | increases expression | ISO | Mgarp (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of MGARP mRNA | CTD | PMID:20880076 | Mgarp | Rat | disodium selenite | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of MGARP mRNA | CTD | PMID:18175754 | Mgarp | Rat | dorsomorphin | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Mgarp | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of MGARP mRNA | CTD | PMID:29391264 | Mgarp | Rat | entinostat | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | entinostat results in increased expression of MGARP mRNA | CTD | PMID:26272509 and PMID:27188386 | Mgarp | Rat | entinostat | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MGARP mRNA | CTD | PMID:27188386 | Mgarp | Rat | formaldehyde | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of MGARP mRNA | CTD | PMID:23649840 | Mgarp | Rat | fulvestrant | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in increased methylation of MGARP gene | CTD | PMID:31601247 | Mgarp | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of MGARP gene | CTD | PMID:22079235 | Mgarp | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of MGARP mRNA | CTD | PMID:33387578 | Mgarp | Rat | GW 4064 | decreases expression | ISO | Mgarp (Mus musculus) | 6480464 | GW 4064 results in decreased expression of MGARP mRNA | CTD | PMID:26655953 | Mgarp | Rat | indometacin | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MGARP mRNA | CTD | PMID:28628672 | Mgarp | Rat | isobutanol | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of MGARP mRNA | CTD | PMID:29432896 | Mgarp | Rat | Licochalcone B | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | licochalcone B results in increased expression of MGARP mRNA | CTD | PMID:33647349 | Mgarp | Rat | manganese atom | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of MGARP mRNA | CTD | PMID:39836092 | Mgarp | Rat | manganese(0) | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of MGARP mRNA | CTD | PMID:39836092 | Mgarp | Rat | manganese(II) chloride | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of MGARP mRNA | CTD | PMID:39836092 | Mgarp | Rat | mercury dibromide | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MGARP mRNA | CTD | PMID:27188386 | Mgarp | Rat | methyl methanesulfonate | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of MGARP mRNA | CTD | PMID:23649840 | Mgarp | Rat | methylmercury chloride | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of MGARP mRNA | CTD | PMID:23179753 | Mgarp | Rat | methylmercury chloride | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of MGARP mRNA | CTD | PMID:28001369 | Mgarp | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of MGARP mRNA | CTD | PMID:36695872 | Mgarp | Rat | Monobutylphthalate | decreases expression | ISO | Mgarp (Mus musculus) | 6480464 | monobutyl phthalate results in decreased expression of MGARP protein | CTD | PMID:36602389 | Mgarp | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | decreases expression | ISO | Mgarp (Mus musculus) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of MGARP mRNA | CTD | PMID:25566086 | Mgarp | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of MGARP mRNA | CTD | PMID:22110744 | Mgarp | Rat | nickel sulfate | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of MGARP mRNA | CTD | PMID:22714537 | Mgarp | Rat | pentanal | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | pentanal results in increased expression of MGARP mRNA | CTD | PMID:26079696 | Mgarp | Rat | perfluorohexanesulfonic acid | increases expression | ISO | Mgarp (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in increased expression of MGARP mRNA | CTD | PMID:37315490 | Mgarp | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of MGARP mRNA | CTD | PMID:35163327 | Mgarp | Rat | phenylmercury acetate | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of MGARP mRNA | CTD | PMID:26272509 | Mgarp | Rat | phenylmercury acetate | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MGARP mRNA | CTD | PMID:27188386 | Mgarp | Rat | potassium chromate | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of MGARP mRNA | CTD | PMID:22079256 | Mgarp | Rat | potassium chromate | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of MGARP mRNA | CTD | PMID:22079256 and PMID:22714537 | Mgarp | Rat | propanal | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of MGARP mRNA | CTD | PMID:26079696 | Mgarp | Rat | SB 431542 | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Mgarp | Rat | silicon dioxide | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of MGARP mRNA | CTD | PMID:23806026 | Mgarp | Rat | sodium arsenite | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of MGARP mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of MGARP mRNA | CTD | PMID:39836092 | Mgarp | Rat | sodium arsenite | increases expression | ISO | Mgarp (Mus musculus) | 6480464 | sodium arsenite results in increased expression of MGARP mRNA | CTD | PMID:37682722 | Mgarp | Rat | sunitinib | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | Sunitinib results in increased expression of MGARP mRNA | CTD | PMID:31533062 | Mgarp | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of MGARP mRNA | CTD | PMID:27914986 | Mgarp | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of MGARP mRNA | CTD | PMID:34492290 | Mgarp | Rat | thioacetamide | increases methylation | EXP | | 6480464 | Thioacetamide results in increased methylation of MGARP promoter | CTD | PMID:27914986 | Mgarp | Rat | titanium dioxide | decreases expression | ISO | Mgarp (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of MGARP mRNA | CTD | PMID:29264374 | Mgarp | Rat | trichostatin A | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | trichostatin A results in increased expression of MGARP mRNA | CTD | PMID:26705709 and PMID:27188386 | Mgarp | Rat | triclosan | decreases expression | ISO | MGARP (Homo sapiens) | 6480464 | Triclosan results in decreased expression of MGARP mRNA | CTD | PMID:30510588 | Mgarp | Rat | trovafloxacin | decreases expression | ISO | Mgarp (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of MGARP mRNA | CTD | PMID:35537566 | Mgarp | Rat | valproic acid | affects expression | ISO | MGARP (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MGARP mRNA | CTD | PMID:25979313 | Mgarp | Rat | valproic acid | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MGARP mRNA | CTD | PMID:23179753 more ... | Mgarp | Rat | valproic acid | multiple interactions | ISO | MGARP (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MGARP mRNA | CTD | PMID:27188386 | Mgarp | Rat | vorinostat | increases expression | ISO | MGARP (Homo sapiens) | 6480464 | vorinostat results in increased expression of MGARP mRNA | CTD | PMID:27188386 | |