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Gene: Klb (klotho beta) Rattus norvegicus
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Symbol: Klb
Name: klotho beta
RGD ID: 1308227
Description: Predicted to have fibroblast growth factor binding activity and fibroblast growth factor receptor binding activity. Predicted to be involved in positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway and positive regulation of cell population proliferation. Orthologous to human KLB (klotho beta); PARTICIPATES IN fibroblast growth factor signaling pathway; INTERACTS WITH (+)-schisandrin B; pravastatin; rotenone.
Type: protein-coding
RefSeq Status: MODEL
Also known as: beta-klotho; Klb-ps1; klotho beta, pseudogene 1; LOC289625; LOW QUALITY PROTEIN: beta-klotho; RGD1308227; similar to betaKlotho protein
Orthologs:
Homo sapiens (human) : KLB (klotho beta)  HGNC  Alliance
Mus musculus (house mouse) : Klb (klotho beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klb (klotho beta)
Pan paniscus (bonobo/pygmy chimpanzee) : KLB (klotho beta)
Canis lupus familiaris (dog) : KLB (klotho beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klb (klotho beta)
Sus scrofa (pig) : KLB (klotho beta)
Chlorocebus sabaeus (African green monkey) : KLB (klotho beta)
Heterocephalus glaber (naked mole-rat) : Klb (klotho beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01444,529,523 - 44,614,093 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01444,362,418 - 44,428,134 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41445,598,875 - 45,650,432 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11445,601,737 - 45,652,823 (-)NCBI
Celera1442,059,574 - 42,094,328 (-)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Klb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308227
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.