F2rl2 (coagulation factor II (thrombin) receptor-like 2) - Rat Genome Database

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Gene: F2rl2 (coagulation factor II (thrombin) receptor-like 2) Rattus norvegicus
Analyze
Symbol: F2rl2
Name: coagulation factor II (thrombin) receptor-like 2
RGD ID: 620871
Description: Predicted to enable proteinase-activated receptor activity and receptor ligand activity. Predicted to be involved in G protein-coupled receptor signaling pathway; ligand-gated ion channel signaling pathway; and positive regulation of insulin secretion. Predicted to be located in apical plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Orthologous to human F2RL2 (coagulation factor II thrombin receptor like 2); PARTICIPATES IN insulin signaling pathway; protease mediated signaling via protease-activated receptor 3; INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: coagulation factor II receptor-like 2; PAR-3; PAR3; protease-activated receptor 3; proteinase-activated receptor 3; thrombin receptor-like 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8228,706,766 - 28,711,808 (+)NCBIGRCr8
GRCr8 Ensembl228,706,501 - 28,712,473 (+)EnsemblGRCr8 Ensembl
mRatBN7.2226,972,054 - 26,977,098 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl226,972,054 - 26,977,098 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx234,011,700 - 34,016,699 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0232,111,806 - 32,116,807 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0226,928,439 - 26,933,433 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0226,240,385 - 26,245,533 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl226,240,385 - 26,245,533 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0245,371,780 - 45,376,928 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4226,073,852 - 26,078,618 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera223,033,959 - 23,038,978 (+)NCBICelera
RGSC_v3.1225,994,220 - 25,998,987 (+)NCBI
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (EXP)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-palmitoylglycerol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acetamiprid  (EXP)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-amanitin  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
cyclophosphamide  (EXP)
cyclosporin A  (ISO)
dioxygen  (EXP)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
flavonoids  (EXP)
imidacloprid  (EXP)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury dibromide  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
nickel sulfate  (ISO)
nicotine  (EXP)
nitrates  (ISO)
Nutlin-3  (ISO)
O-methyleugenol  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenformin  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercitrin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cross Talk Pathways Between Coagulation and Inflammation. Foley JH and Conway EM, Circ Res. 2016 Apr 29;118(9):1392-408. doi: 10.1161/CIRCRESAHA.116.306853.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Increase of prothrombin-mRNA after global cerebral ischemia in rats, with constant expression of protease nexin-1 and protease-activated receptors. Riek-Burchardt M, etal., Neurosci Lett 2002 Aug 30;329(2):181-4.
11. Protease-activated receptor subtype expression in developing eye and adult retina of the rat after optic nerve crush. Rohatgi T, etal., J Neurosci Res 2003 Jul 15;73(2):246-54.
12. Transient focal ischemia in rat brain differentially regulates mRNA expression of protease-activated receptors 1 to 4. Rohatgi T, etal., J Neurosci Res 2004 Jan 15;75(2):273-9.
Additional References at PubMed
PMID:1299297   PMID:16403464   PMID:16458856   PMID:16892058   PMID:17136598  


Genomics

Comparative Map Data
F2rl2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8228,706,766 - 28,711,808 (+)NCBIGRCr8
GRCr8 Ensembl228,706,501 - 28,712,473 (+)EnsemblGRCr8 Ensembl
mRatBN7.2226,972,054 - 26,977,098 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl226,972,054 - 26,977,098 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx234,011,700 - 34,016,699 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0232,111,806 - 32,116,807 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0226,928,439 - 26,933,433 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0226,240,385 - 26,245,533 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl226,240,385 - 26,245,533 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0245,371,780 - 45,376,928 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4226,073,852 - 26,078,618 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera223,033,959 - 23,038,978 (+)NCBICelera
RGSC_v3.1225,994,220 - 25,998,987 (+)NCBI
Cytogenetic Map2q12NCBI
F2RL2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38576,615,482 - 76,623,403 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl576,615,482 - 76,623,413 (-)EnsemblGRCh38hg38GRCh38
GRCh37575,911,307 - 75,919,228 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36575,947,063 - 75,954,996 (-)NCBINCBI36Build 36hg18NCBI36
Build 34575,947,063 - 75,954,996NCBI
Celera571,805,260 - 71,813,193 (-)NCBICelera
Cytogenetic Map5q13.3NCBI
HuRef571,119,015 - 71,126,968 (-)NCBIHuRef
CHM1_1575,344,295 - 75,352,247 (-)NCBICHM1_1
T2T-CHM13v2.0577,097,223 - 77,105,145 (-)NCBIT2T-CHM13v2.0
F2rl2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391395,833,428 - 95,839,276 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1395,833,361 - 95,839,247 (+)EnsemblGRCm39 Ensembl
GRCm381395,696,920 - 95,702,768 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1395,696,853 - 95,702,739 (+)EnsemblGRCm38mm10GRCm38
MGSCv371396,466,875 - 96,472,723 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361396,797,656 - 96,803,438 (+)NCBIMGSCv36mm8
Celera1399,313,808 - 99,319,652 (+)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.38NCBI
F2rl2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542524,246,333 - 24,254,887 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542524,246,333 - 24,254,887 (+)NCBIChiLan1.0ChiLan1.0
F2RL2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2438,681,399 - 38,689,370 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1536,835,029 - 36,842,961 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0538,680,372 - 38,688,509 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1539,297,424 - 39,305,370 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl539,297,424 - 39,305,370 (+)Ensemblpanpan1.1panPan2
F2RL2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1329,967,278 - 29,974,316 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl329,967,312 - 29,972,872 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha331,206,044 - 31,213,084 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0329,891,456 - 29,898,496 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl329,891,199 - 29,898,494 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1329,822,502 - 29,829,542 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0329,802,374 - 29,809,212 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0330,172,976 - 30,180,016 (+)NCBIUU_Cfam_GSD_1.0
F2rl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213190,515,607 - 190,522,114 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936549337,024 - 342,948 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936549336,871 - 342,992 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
F2RL2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl285,534,191 - 85,541,821 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1285,534,188 - 85,542,062 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2287,181,035 - 87,188,670 (+)NCBISscrofa10.2Sscrofa10.2susScr3
F2RL2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1470,887,979 - 70,895,419 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl470,886,113 - 70,895,113 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604919,720,145 - 19,727,047 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
F2rl2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248691,073,656 - 1,077,635 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248691,073,481 - 1,078,207 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in F2rl2
49 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:32
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000024292
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
738010Lnnr3Liver neoplastic nodule remodeling QTL 32.94liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)2142977529Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
9590080Insglur4Insulin/glucose ratio QTL 428.70.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)2615276751152767Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
731166Mamtr2Mammary tumor resistance QTL 20.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358154623581Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1600379Mcs18Mammary carcinoma susceptibility QTL 182.6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358144538110Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)2573632550736325Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat

Markers in Region
F2rl2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2226,975,969 - 26,976,089 (+)MAPPERmRatBN7.2
Rnor_6.0226,244,405 - 26,244,524NCBIRnor6.0
Rnor_5.0245,375,800 - 45,375,919UniSTSRnor5.0
Celera223,037,850 - 23,037,969UniSTS
Cytogenetic Map2q12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
9 10 49 104 89 88 57 25 57 6 213 94 11 84 45 57 31 12 12

Sequence


Ensembl Acc Id: ENSRNOT00000024292   ⟹   ENSRNOP00000024292
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl228,706,501 - 28,712,473 (+)Ensembl
mRatBN7.2 Ensembl226,972,054 - 26,977,098 (+)Ensembl
Rnor_6.0 Ensembl226,240,385 - 26,245,533 (+)Ensembl
RefSeq Acc Id: NM_053313   ⟹   NP_445765
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8228,706,766 - 28,711,808 (+)NCBI
mRatBN7.2226,972,054 - 26,977,098 (+)NCBI
Rnor_6.0226,240,385 - 26,245,533 (+)NCBI
Rnor_5.0245,371,780 - 45,376,928 (+)NCBI
RGSC_v3.4226,073,852 - 26,078,618 (+)RGD
Celera223,033,959 - 23,038,978 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_445765 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL26789 (Get FASTA)   NCBI Sequence Viewer  
  EDM10105 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024292
GenBank Protein Q920E1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_445765   ⟸   NM_053313
- Peptide Label: precursor
- UniProtKB: Q920E1 (UniProtKB/Swiss-Prot),   A6I4Z7 (UniProtKB/TrEMBL),   F1LPU1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024292   ⟸   ENSRNOT00000024292
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q920E1-F1-model_v2 AlphaFold Q920E1 1-368 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691078
Promoter ID:EPDNEW_R1603
Type:initiation region
Name:F2rl2_1
Description:coagulation factor II receptor-like 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0226,240,363 - 26,240,423EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620871 AgrOrtholog
BioCyc Gene G2FUF-54799 BioCyc
Ensembl Genes ENSRNOG00000018054 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000024292 ENTREZGENE
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
  Prot_act_rcpt_3 UniProtKB/Swiss-Prot
  Protea_act_rcpt UniProtKB/Swiss-Prot
KEGG Report rno:29636 UniProtKB/Swiss-Prot
NCBI Gene 29636 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot
  PROTEINASE-ACTIVATED RECEPTOR 3 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen F2rl2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot
  PROTEASEAR UniProtKB/Swiss-Prot
  PROTEASEAR3 UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018054 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot
UniProt A6I4Z7 ENTREZGENE, UniProtKB/TrEMBL
  F1LPU1 ENTREZGENE, UniProtKB/TrEMBL
  PAR3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 F2rl2  coagulation factor II (thrombin) receptor-like 2      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 F2rl2  coagulation factor II (thrombin) receptor-like 2      Symbol and Name status set to provisional 70820 PROVISIONAL