Dync2h1 (dynein cytoplasmic 2 heavy chain 1) - Rat Genome Database

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Gene: Dync2h1 (dynein cytoplasmic 2 heavy chain 1) Rattus norvegicus
Analyze
Symbol: Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
RGD ID: 71042
Description: Enables dynein light intermediate chain binding activity. Involved in cilium assembly. Located in apical part of cell. Part of cytoplasmic dynein complex. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy and asphyxiating thoracic dystrophy 3. Orthologous to human DYNC2H1 (dynein cytoplasmic 2 heavy chain 1); PARTICIPATES IN phagocytosis pathway; vasopressin signaling pathway via receptor type 2; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cytoplasmic dynein 2 heavy chain 1; cytoplasmic dynein 2 heavy chain 1-like; cytoplasmic dynein heavy chain 2; Dhc1b; Dnch2; Dnchc2; dynein heavy chain isotype 1B; dynein, cytoplasmic, heavy chain 2; dynein, cytoplasmic, heavy polypeptide 2; dynein-like protein 4; LOC103689995
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8812,473,955 - 12,697,075 (-)NCBIGRCr8
mRatBN7.284,189,067 - 4,412,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl84,189,257 - 4,412,183 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx88,150,654 - 8,371,658 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.086,448,441 - 6,669,441 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.084,448,735 - 4,671,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.085,217,054 - 5,436,969 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl85,217,217 - 5,429,581 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.085,224,193 - 5,444,010 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.085,158,973 - 5,196,018 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.483,826,843 - 4,072,644 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.183,826,842 - 4,072,644 (-)NCBI
Celera85,755,003 - 5,975,984 (-)NCBICelera
Cytogenetic Map8q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
9+2 motile cilium  (IBA)
apical part of cell  (IDA,IEA,ISO)
axoneme  (IBA,IEA,ISO)
cilium  (IEA)
cytoplasm  (IEA)
cytoplasmic dynein complex  (IBA,IDA,IEA,ISO)
dynein complex  (IEA)
Golgi apparatus  (IEA,ISO)
microtubule  (IEA,ISO)
motile cilium  (IEA,ISO)
plasma membrane  (IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Evidence for four cytoplasmic dynein heavy chain isoforms in rat testis. Criswell PS and Asai DJ, Mol Biol Cell. 1998 Feb;9(2):237-47. doi: 10.1091/mbc.9.2.237.
2. A novel cytoplasmic dynein heavy chain: expression of DHC1b in mammalian ciliated epithelial cells. Criswell PS, etal., J Cell Sci. 1996 Jul;109 ( Pt 7):1891-8.
3. NEK1 and DYNC2H1 are both involved in short rib polydactyly Majewski type but not in Beemer Langer cases. El Hokayem J, etal., J Med Genet. 2012 Apr;49(4):227-33. doi: 10.1136/jmedgenet-2011-100717.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cells. Mikami A, etal., J Cell Sci. 2002 Dec 15;115(Pt 24):4801-8.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene. Neesen J, etal., Gene 1997 Oct 24;200(1-2):193-202.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Identification and molecular evolution of new dynein-like protein sequences in rat brain. Tanaka Y, etal., J Cell Sci 1995 May;108 ( Pt 5):1883-93.
Additional References at PubMed
PMID:8666668   PMID:8812413   PMID:12802074   PMID:15755804   PMID:15866890   PMID:16061793   PMID:16229832   PMID:17289665   PMID:18488998   PMID:19056867   PMID:21525035   PMID:21552265  
PMID:21723285   PMID:22689656   PMID:22871113   PMID:25807483   PMID:25830415  


Genomics

Comparative Map Data
Dync2h1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8812,473,955 - 12,697,075 (-)NCBIGRCr8
mRatBN7.284,189,067 - 4,412,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl84,189,257 - 4,412,183 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx88,150,654 - 8,371,658 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.086,448,441 - 6,669,441 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.084,448,735 - 4,671,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.085,217,054 - 5,436,969 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl85,217,217 - 5,429,581 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.085,224,193 - 5,444,010 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.085,158,973 - 5,196,018 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.483,826,843 - 4,072,644 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.183,826,842 - 4,072,644 (-)NCBI
Celera85,755,003 - 5,975,984 (-)NCBICelera
Cytogenetic Map8q11NCBI
DYNC2H1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811103,109,426 - 103,479,863 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11103,109,410 - 103,479,863 (+)EnsemblGRCh38hg38GRCh38
GRCh3711102,980,155 - 103,350,591 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,485,370 - 102,855,801 (+)NCBINCBI36Build 36hg18NCBI36
Celera11100,141,694 - 100,511,960 (+)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef1198,908,876 - 99,279,409 (+)NCBIHuRef
CHM1_111102,863,127 - 103,233,529 (+)NCBICHM1_1
T2T-CHM13v2.011103,113,153 - 103,483,765 (+)NCBIT2T-CHM13v2.0
Dync2h1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3996,928,550 - 7,177,619 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl96,928,503 - 7,184,446 (-)EnsemblGRCm39 Ensembl
GRCm3896,928,550 - 7,178,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl96,928,503 - 7,184,446 (-)EnsemblGRCm38mm10GRCm38
MGSCv3796,928,503 - 7,177,046 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3696,928,503 - 7,177,046 (-)NCBIMGSCv36mm8
Celera94,333,469 - 4,580,163 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
Dync2h1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554126,268,214 - 6,518,468 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554126,267,726 - 6,518,888 (+)NCBIChiLan1.0ChiLan1.0
DYNC2H1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29103,904,555 - 104,278,595 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111104,993,041 - 105,366,969 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01198,051,788 - 98,425,676 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111101,536,471 - 101,909,194 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11101,536,471 - 101,909,194 (+)Ensemblpanpan1.1panPan2
DYNC2H1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1528,566,604 - 28,727,416 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl528,388,664 - 28,727,334 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha528,326,886 - 28,673,935 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0528,436,359 - 28,778,770 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1528,468,389 - 28,813,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0528,354,759 - 28,693,562 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0528,528,813 - 28,868,231 (-)NCBIUU_Cfam_GSD_1.0
Dync2h1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494786,622,656 - 86,951,875 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365514,584,438 - 4,913,825 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365514,584,438 - 4,913,829 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNC2H1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl933,720,877 - 34,040,188 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1933,720,920 - 34,039,954 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2937,664,274 - 37,736,257 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DYNC2H1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,484,090 - 94,849,960 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,484,512 - 94,849,581 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604331,022,418 - 31,385,767 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dync2h1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249181,730,708 - 2,071,072 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249181,730,675 - 2,071,231 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dync2h1
1026 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:21
Count of miRNA genes:21
Interacting mature miRNAs:21
Transcripts:ENSRNOT00000044174
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)8209764047097640Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8124597739Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)8209764047097640Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)8209764047097640Rat
2317882Alcrsp24Alcohol response QTL 243.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)8125902202Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)8209764047097640Rat

Markers in Region
RH134854  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.284,189,362 - 4,189,554 (+)MAPPERmRatBN7.2
Rnor_6.085,217,160 - 5,217,351NCBIRnor6.0
Rnor_5.085,224,299 - 5,224,490UniSTSRnor5.0
RGSC_v3.483,826,949 - 3,827,140UniSTSRGSC3.4
Celera85,755,109 - 5,755,300UniSTS
Cytogenetic Map8q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 6 4 55 12 33 8
Low 3 42 50 40 15 40 8 8 19 23 8 3 8
Below cutoff 1 1 1 1 3

Sequence


RefSeq Acc Id: ENSRNOT00000044174   ⟹   ENSRNOP00000043252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl84,189,257 - 4,412,183 (-)Ensembl
Rnor_6.0 Ensembl85,217,217 - 5,429,581 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112659   ⟹   ENSRNOP00000097714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl84,189,257 - 4,412,183 (-)Ensembl
RefSeq Acc Id: NM_023024   ⟹   NP_075413
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8812,473,955 - 12,697,058 (-)NCBI
mRatBN7.284,189,067 - 4,412,183 (-)NCBI
Rnor_6.085,217,054 - 5,436,969 (-)NCBI
Rnor_5.085,224,193 - 5,444,010 (-)NCBI
RGSC_v3.483,826,843 - 4,072,644 (-)RGD
Celera85,755,003 - 5,975,984 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063266103   ⟹   XP_063122173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8812,474,145 - 12,689,770 (-)NCBI
RefSeq Acc Id: XM_063266104   ⟹   XP_063122174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8812,474,145 - 12,689,770 (-)NCBI
RefSeq Acc Id: XM_063266105   ⟹   XP_063122175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8812,474,145 - 12,689,770 (-)NCBI
RefSeq Acc Id: XM_063266106   ⟹   XP_063122176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8812,474,145 - 12,697,075 (-)NCBI
RefSeq Acc Id: XR_010054024
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8812,519,083 - 12,689,770 (-)NCBI
RefSeq Acc Id: NP_075413   ⟸   NM_023024
- UniProtKB: Q9JJ79 (UniProtKB/Swiss-Prot),   Q63167 (UniProtKB/Swiss-Prot),   P70576 (UniProtKB/Swiss-Prot),   D3ZBB8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000043252   ⟸   ENSRNOT00000044174
RefSeq Acc Id: ENSRNOP00000097714   ⟸   ENSRNOT00000112659
RefSeq Acc Id: XP_063122176   ⟸   XM_063266106
- Peptide Label: isoform X4
- UniProtKB: Q9JJ79 (UniProtKB/Swiss-Prot),   Q63167 (UniProtKB/Swiss-Prot),   P70576 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063122174   ⟸   XM_063266104
- Peptide Label: isoform X2
- UniProtKB: Q9JJ79 (UniProtKB/Swiss-Prot),   Q63167 (UniProtKB/Swiss-Prot),   P70576 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063122175   ⟸   XM_063266105
- Peptide Label: isoform X3
- UniProtKB: Q9JJ79 (UniProtKB/Swiss-Prot),   Q63167 (UniProtKB/Swiss-Prot),   P70576 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063122173   ⟸   XM_063266103
- Peptide Label: isoform X1
- UniProtKB: Q9JJ79 (UniProtKB/Swiss-Prot),   Q63167 (UniProtKB/Swiss-Prot),   P70576 (UniProtKB/Swiss-Prot),   A0A8I6ANN6 (UniProtKB/TrEMBL)
Protein Domains
AAA+ ATPase

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695729
Promoter ID:EPDNEW_R6253
Type:initiation region
Name:Dync2h1_1
Description:dynein cytoplasmic 2 heavy chain 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.085,429,606 - 5,429,666EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71042 AgrOrtholog
BioCyc Gene G2FUF-31795 BioCyc
Ensembl Genes ENSRNOG00000032070 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044174 ENTREZGENE
  ENSRNOT00000044174.6 UniProtKB/TrEMBL
  ENSRNOT00000112659.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.1220 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.8.710 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.8.720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.1270.280 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.140.100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.1120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.920.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.920.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.490.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.20.180.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.140.1060 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DHC_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DYNC2H1_AAA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA1S UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_C_barrel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_HC_stalk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_chain_D4_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_D6_P-loop UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_dom-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_dom-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:65209 UniProtKB/Swiss-Prot
NCBI Gene 65209 ENTREZGENE
PANTHER CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DYNEIN HEAVY CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AAA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DHC_N1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DHC_N2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DYNC2H1_AAA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF12777 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dync2h1 PhenoGen
RatGTEx ENSRNOG00000032070 RatGTEx
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6ANN6 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBB8 ENTREZGENE, UniProtKB/TrEMBL
  DYHC2_RAT UniProtKB/Swiss-Prot
  P70576 ENTREZGENE
  Q63167 ENTREZGENE
  Q9JJ79 ENTREZGENE
UniProt Secondary P70576 UniProtKB/Swiss-Prot
  Q63167 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Dync2h1  dynein cytoplasmic 2 heavy chain 1  LOC103689995  cytoplasmic dynein 2 heavy chain 1-like  Data merged from RGD:9147056 737654 PROVISIONAL
2014-08-25 LOC103689995  cytoplasmic dynein 2 heavy chain 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-18 Dync2h1  dynein cytoplasmic 2 heavy chain 1  Dnch2  dynein, cytoplasmic, heavy polypeptide 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Dnch2  dynein, cytoplasmic, heavy polypeptide 2    dynein, cytoplasmic, heavy chain 2  Name updated 1299863 APPROVED
2002-07-09 Dnch2  dynein, cytoplasmic, heavy chain 2      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression expression in adult highest in testis, and also detectable in brain and ovary by Northern blot; expression in neonatal brain highest at birth 632520
gene_transcript may have splice varients in rat brain 632520