Dync2h1 (dynein cytoplasmic 2 heavy chain 1) - Rat Genome Database

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Gene: Dync2h1 (dynein cytoplasmic 2 heavy chain 1) Ictidomys tridecemlineatus
Analyze
Symbol: Dync2h1
Name: dynein cytoplasmic 2 heavy chain 1
RGD ID: 12549083
Description: ENCODES a protein that exhibits minus-end-directed microtubule motor activity (ortholog); INVOLVED IN cilium assembly (ortholog); coronary vasculature development (ortholog); determination of left/right symmetry (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); asphyxiating thoracic dystrophy 1 (ortholog); asphyxiating thoracic dystrophy 3 (ortholog); FOUND IN apical part of cell (ortholog); cytoplasmic dynein complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytoplasmic dynein 2 heavy chain 1; dynein cytoplasmic 2 heavy chain 1, transcript variant X1; dynein cytoplasmic 2 heavy chain 1, transcript variant X2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494786,622,656 - 86,951,875 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365514,584,438 - 4,913,825 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365514,584,438 - 4,913,829 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Dync2h1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494786,622,656 - 86,951,875 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365514,584,438 - 4,913,825 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365514,584,438 - 4,913,829 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNC2H1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811103,109,426 - 103,479,863 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11103,109,410 - 103,479,863 (+)EnsemblGRCh38hg38GRCh38
GRCh3711102,980,155 - 103,350,591 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611102,485,370 - 102,855,801 (+)NCBINCBI36Build 36hg18NCBI36
Celera11100,141,694 - 100,511,960 (+)NCBICelera
Cytogenetic Map11q22.3NCBI
HuRef1198,908,876 - 99,279,409 (+)NCBIHuRef
CHM1_111102,863,127 - 103,233,529 (+)NCBICHM1_1
T2T-CHM13v2.011103,113,153 - 103,483,765 (+)NCBIT2T-CHM13v2.0
Dync2h1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3996,928,550 - 7,177,619 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl96,928,503 - 7,184,446 (-)EnsemblGRCm39 Ensembl
GRCm3896,928,550 - 7,178,306 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl96,928,503 - 7,184,446 (-)EnsemblGRCm38mm10GRCm38
MGSCv3796,928,503 - 7,177,046 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3696,928,503 - 7,177,046 (-)NCBIMGSCv36mm8
Celera94,333,469 - 4,580,163 (-)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
Dync2h1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8812,473,955 - 12,697,075 (-)NCBIGRCr8
mRatBN7.284,189,067 - 4,412,183 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl84,189,257 - 4,412,183 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx88,150,654 - 8,371,658 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.086,448,441 - 6,669,441 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.084,448,735 - 4,671,840 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.085,217,054 - 5,436,969 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl85,217,217 - 5,429,581 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.085,224,193 - 5,444,010 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.085,158,973 - 5,196,018 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.483,826,843 - 4,072,644 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.183,826,842 - 4,072,644 (-)NCBI
Celera85,755,003 - 5,975,984 (-)NCBICelera
Cytogenetic Map8q11NCBI
Dync2h1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554126,268,214 - 6,518,468 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554126,267,726 - 6,518,888 (+)NCBIChiLan1.0ChiLan1.0
DYNC2H1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29103,904,555 - 104,278,595 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111104,993,041 - 105,366,969 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01198,051,788 - 98,425,676 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111101,536,471 - 101,909,194 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11101,536,471 - 101,909,194 (+)Ensemblpanpan1.1panPan2
DYNC2H1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1528,566,604 - 28,727,416 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl528,388,664 - 28,727,334 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha528,326,886 - 28,673,935 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0528,436,359 - 28,778,770 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1528,468,389 - 28,813,742 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0528,354,759 - 28,693,562 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0528,528,813 - 28,868,231 (-)NCBIUU_Cfam_GSD_1.0
DYNC2H1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl933,720,877 - 34,040,188 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1933,720,920 - 34,039,954 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2937,664,274 - 37,736,257 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DYNC2H1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1194,484,090 - 94,849,960 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl194,484,512 - 94,849,581 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604331,022,418 - 31,385,767 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dync2h1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249181,730,708 - 2,071,072 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249181,730,675 - 2,071,231 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000024167   ⟹   ENSSTOP00000023838
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365514,584,438 - 4,913,825 (-)Ensembl
RefSeq Acc Id: ENSSTOT00000033653   ⟹   ENSSTOP00000027491
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365514,584,438 - 4,913,825 (-)Ensembl
RefSeq Acc Id: XM_005329089   ⟹   XP_005329146
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494786,622,830 - 86,951,875 (+)NCBI
SpeTri2.0NW_0049365514,584,438 - 4,913,679 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005329090   ⟹   XP_005329147
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494786,622,830 - 86,951,837 (+)NCBI
SpeTri2.0NW_0049365514,584,684 - 4,913,829 (-)NCBI
Sequence:
RefSeq Acc Id: XM_040285143   ⟹   XP_040141077
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494786,622,660 - 86,951,751 (+)NCBI
RefSeq Acc Id: XR_005733720
Type: NON-CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494786,622,656 - 86,703,462 (+)NCBI
Protein Sequences
Protein RefSeqs XP_005329146 (Get FASTA)   NCBI Sequence Viewer  
  XP_005329147 (Get FASTA)   NCBI Sequence Viewer  
  XP_040141077 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000023838.2
  ENSSTOP00000027491.1
GenBank Protein KAG3286443 (Get FASTA)   NCBI Sequence Viewer  
  KAG3286444 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005329146   ⟸   XM_005329089
- Peptide Label: isoform X3
- UniProtKB: I3NHJ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005329147   ⟸   XM_005329090
- Peptide Label: isoform X1
- UniProtKB: A0A287D1M4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_040141077   ⟸   XM_040285143
- Peptide Label: isoform X2
RefSeq Acc Id: ENSSTOP00000027491   ⟸   ENSSTOT00000033653
RefSeq Acc Id: ENSSTOP00000023838   ⟸   ENSSTOT00000024167
Protein Domains
AAA+ ATPase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000026849 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024167.2 UniProtKB/TrEMBL
  ENSSTOT00000033653.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.1220 UniProtKB/TrEMBL
  1.10.8.710 UniProtKB/TrEMBL
  1.10.8.720 UniProtKB/TrEMBL
  1.20.1270.280 UniProtKB/TrEMBL
  1.20.140.100 UniProtKB/TrEMBL
  1.20.58.1120 UniProtKB/TrEMBL
  1.20.920.20 UniProtKB/TrEMBL
  1.20.920.30 UniProtKB/TrEMBL
  3.10.490.20 UniProtKB/TrEMBL
  3.20.180.20 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  6.10.140.1060 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  AAA_6 UniProtKB/TrEMBL
  AAA_9 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  AAA_lid_11_sf UniProtKB/TrEMBL
  DHC_fam UniProtKB/TrEMBL
  DYNC2H1_AAA_dom UniProtKB/TrEMBL
  Dynein_2_N UniProtKB/TrEMBL
  Dynein_AAA1S UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_C_barrel UniProtKB/TrEMBL
  Dynein_HC_stalk UniProtKB/TrEMBL
  Dynein_heavy_chain_D4_dom UniProtKB/TrEMBL
  Dynein_heavy_D6_P-loop UniProtKB/TrEMBL
  Dynein_heavy_linker UniProtKB/TrEMBL
  Dynein_heavy_tail UniProtKB/TrEMBL
  Dynein_linker_3 UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Dync2h1 ENTREZGENE
PANTHER CYTOPLASMIC DYNEIN 2 HEAVY CHAIN 1 UniProtKB/TrEMBL
  DYNEIN HEAVY CHAIN UniProtKB/TrEMBL
Pfam AAA_6 UniProtKB/TrEMBL
  AAA_7 UniProtKB/TrEMBL
  AAA_8 UniProtKB/TrEMBL
  AAA_9 UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/TrEMBL
  DHC_N1 UniProtKB/TrEMBL
  DHC_N2 UniProtKB/TrEMBL
  DYNC2H1_AAA_dom UniProtKB/TrEMBL
  Dynein_C UniProtKB/TrEMBL
  Dynein_heavy UniProtKB/TrEMBL
  PF12777 UniProtKB/TrEMBL
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A287D1M4 ENTREZGENE, UniProtKB/TrEMBL
  I3NHJ1 ENTREZGENE, UniProtKB/TrEMBL