Gene: Txnrd2 (thioredoxin reductase 2) Rattus norvegicus
Symbol: Txnrd2
Name: thioredoxin reductase 2
Description: ENCODES a protein that exhibits protein homodimerization activity; thioredoxin-disulfide reductase activity; INVOLVED IN response to drug; response to hyperoxia; response to selenium ion; PARTICIPATES IN pyrimidine metabolic pathway; selenoamino acid metabolic pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; Reperfusion Injury; autism spectrum disorder (ortholog); FOUND IN axon; cytoplasm; dendrite; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; all-trans-retinoic acid
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC93435; thioredoxin reductase 2, mitochondrial; thioredoxin reductase TR3; Tr3; Trxr2; Trxrd2
Homo sapiens (human) : TXNRD2 (thioredoxin reductase 2)  HGNC  Alliance
Mus musculus (house mouse) : Txnrd2 (thioredoxin reductase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Txnrd2 (thioredoxin reductase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TXNRD2 (thioredoxin reductase 2)
Canis lupus familiaris (dog) : TXNRD2 (thioredoxin reductase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Txnrd2 (thioredoxin reductase 2)
Sus scrofa (pig) : TXNRD2 (thioredoxin reductase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01186,667,994 - 86,716,063 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01189,762,304 - 89,809,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41184,513,361 - 84,561,673 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11184,553,962 - 84,602,292 (-)NCBI
Celera1181,297,140 - 81,345,203 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Txnrd2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61960
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE