Arap2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2) - Rat Genome Database

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Pathways
Gene: Arap2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2) Rattus norvegicus
Analyze
Symbol: Arap2
Name: ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
RGD ID: 1306452
Description: Predicted to enable GTPase activator activity and phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in regulation of actin cytoskeleton organization. Predicted to be active in cytoplasm. Orthologous to human ARAP2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2; centaurin, delta 1; Centd1; LOC305367
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81450,921,323 - 51,120,972 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1450,921,713 - 51,120,962 (+)EnsemblGRCr8
mRatBN7.21446,717,657 - 46,917,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1446,718,760 - 46,917,154 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1451,125,503 - 51,322,104 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01452,427,974 - 52,624,570 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01448,824,406 - 49,021,017 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01448,726,033 - 48,922,809 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1448,726,045 - 48,922,983 (+)Ensemblrn6Rnor6.0
Rnor_5.01448,892,214 - 49,090,667 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41450,594,829 - 50,789,829 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1446,023,257 - 46,220,741 (+)NCBICelera
RGSC_v3.11450,611,833 - 50,790,398 (+)NCBI
Cytogenetic Map14q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-Nitrobenzanthrone  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clorgyline  (ISO)
coenzyme Q10  (ISO)
Cuprizon  (EXP)
cyclosporin A  (EXP,ISO)
DDT  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fluoranthene  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
GSK-J4  (ISO)
hydrogen cyanide  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (ISO)
methimazole  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (EXP)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paracetamol  (ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium cyanide  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercitrin  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
terbufos  (ISO)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11804589  


Genomics

Comparative Map Data
Arap2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81450,921,323 - 51,120,972 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1450,921,713 - 51,120,962 (+)EnsemblGRCr8
mRatBN7.21446,717,657 - 46,917,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1446,718,760 - 46,917,154 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1451,125,503 - 51,322,104 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01452,427,974 - 52,624,570 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01448,824,406 - 49,021,017 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01448,726,033 - 48,922,809 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1448,726,045 - 48,922,983 (+)Ensemblrn6Rnor6.0
Rnor_5.01448,892,214 - 49,090,667 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41450,594,829 - 50,789,829 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1446,023,257 - 46,220,741 (+)NCBICelera
RGSC_v3.11450,611,833 - 50,790,398 (+)NCBI
Cytogenetic Map14q11NCBI
ARAP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38436,005,404 - 36,244,784 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl435,948,221 - 36,244,514 (-)Ensemblhg38GRCh38
GRCh37436,007,026 - 36,246,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36435,744,017 - 35,922,374 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34435,890,187 - 35,983,929NCBI
Celera436,507,143 - 36,685,553 (-)NCBICelera
Cytogenetic Map4p14NCBI
HuRef435,394,038 - 35,572,297 (-)NCBIHuRef
CHM1_1436,066,734 - 36,245,096 (-)NCBICHM1_1
T2T-CHM13v2.0435,974,325 - 36,213,757 (-)NCBIT2T-CHM13v2.0
Arap2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39562,759,788 - 62,923,874 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl562,759,788 - 62,923,502 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38562,602,445 - 62,766,192 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl562,602,445 - 62,766,159 (-)Ensemblmm10GRCm38
MGSCv37562,993,684 - 63,157,416 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36562,890,682 - 63,054,331 (-)NCBIMGSCv36mm8
Celera559,899,718 - 60,063,218 (-)NCBICelera
Cytogenetic Map5C3.1NCBI
cM Map532.04NCBI
Arap2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544310,537,758 - 10,717,301 (+)Ensembl
ChiLan1.0NW_00495544310,537,763 - 10,719,329 (+)NCBIChiLan1.0ChiLan1.0
ARAP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2336,243,314 - 36,462,448 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1436,432,386 - 36,651,468 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0430,382,528 - 30,561,731 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1436,244,283 - 36,422,965 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl436,244,283 - 36,422,965 (-)EnsemblpanPan2panpan1.1
ARAP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1375,641,034 - 75,832,145 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl375,643,013 - 75,815,274 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha378,128,989 - 78,318,159 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0376,422,480 - 76,613,649 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl376,423,621 - 76,614,886 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1375,688,311 - 75,879,140 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0375,844,199 - 76,035,013 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0376,219,926 - 76,410,644 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528541,730,685 - 41,930,525 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364824,386,934 - 4,553,332 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364824,385,788 - 4,567,646 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARAP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl827,771,423 - 27,960,542 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1827,771,413 - 27,960,564 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2829,137,042 - 29,327,243 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARAP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12714,036,751 - 14,215,997 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2714,052,478 - 14,214,050 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604760,484,586 - 60,724,580 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arap2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248404,635,818 - 4,793,179 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248404,635,446 - 4,809,618 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Arap2
803 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:556
Count of miRNA genes:271
Interacting mature miRNAs:343
Transcripts:ENSRNOT00000003014
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143123808072970315Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142252151767521517Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141889519263895192Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141790672654251504Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat

Markers in Region
D14Rat46  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21445,792,708 - 45,792,904 (+)MAPPERmRatBN7.2
mRatBN7.21446,731,111 - 46,731,319 (+)MAPPERmRatBN7.2
Rnor_6.01448,738,353 - 48,738,560NCBIRnor6.0
Rnor_6.01447,716,056 - 47,716,251NCBIRnor6.0
Rnor_5.01448,904,215 - 48,904,422UniSTSRnor5.0
Rnor_5.01447,891,714 - 47,891,909UniSTSRnor5.0
RGSC_v3.41450,607,501 - 50,607,708UniSTSRGSC3.4
RGSC_v3.41448,529,615 - 48,529,810UniSTSRGSC3.4
RGSC_v3.41450,607,500 - 50,607,708RGDRGSC3.4
Celera1444,897,721 - 44,897,916UniSTS
Celera1446,035,608 - 46,035,813UniSTS
RGSC_v3.11450,609,891 - 50,610,099RGD
SHRSP x BN Map1428.34UniSTS
SHRSP x BN Map1428.34RGD
Cytogenetic Map14q11UniSTS
D14Rat35  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81451,025,619 - 51,025,822 (+)Marker Load Pipeline
mRatBN7.21446,821,968 - 46,822,171 (+)MAPPERmRatBN7.2
Rnor_6.01448,827,628 - 48,827,830NCBIRnor6.0
Rnor_5.01448,994,868 - 48,995,070UniSTSRnor5.0
RGSC_v3.41450,694,700 - 50,694,903RGDRGSC3.4
RGSC_v3.41450,694,701 - 50,694,903UniSTSRGSC3.4
Celera1446,125,352 - 46,125,558UniSTS
RGSC_v3.11450,697,091 - 50,697,294RGD
SHRSP x BN Map1428.2599UniSTS
SHRSP x BN Map1428.2599RGD
Cytogenetic Map14q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001437162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005492953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000031638   ⟹   ENSRNOP00000035496
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1448,740,190 - 48,741,187 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082599   ⟹   ENSRNOP00000070433
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1450,921,713 - 51,120,962 (+)Ensembl
mRatBN7.2 Ensembl1446,718,760 - 46,917,154 (+)Ensembl
Rnor_6.0 Ensembl1448,768,537 - 48,922,983 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086646   ⟹   ENSRNOP00000074225
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1450,921,793 - 51,120,585 (+)Ensembl
mRatBN7.2 Ensembl1446,718,760 - 46,917,154 (+)Ensembl
Rnor_6.0 Ensembl1448,726,045 - 48,922,807 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090271   ⟹   ENSRNOP00000071296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1448,764,670 - 48,765,797 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000164131   ⟹   ENSRNOP00000103220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1450,921,713 - 51,120,962 (+)Ensembl
RefSeq Acc Id: NM_001107216   ⟹   NP_001100686
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,922,415 - 51,120,796 (+)NCBI
mRatBN7.21446,718,760 - 46,917,154 (+)NCBI
Rnor_6.01448,726,045 - 48,922,807 (+)NCBI
Rnor_5.01448,892,214 - 49,090,667 (+)NCBI
RGSC_v3.41450,594,829 - 50,789,829 (+)RGD
Celera1446,023,257 - 46,220,741 (+)RGD
Sequence:
RefSeq Acc Id: XM_039091927   ⟹   XP_038947855
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,473 - 51,120,972 (+)NCBI
mRatBN7.21446,718,277 - 46,917,321 (+)NCBI
RefSeq Acc Id: XM_039091929   ⟹   XP_038947857
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,323 - 51,120,972 (+)NCBI
mRatBN7.21446,717,657 - 46,917,326 (+)NCBI
RefSeq Acc Id: XM_039091930   ⟹   XP_038947858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,473 - 51,120,972 (+)NCBI
mRatBN7.21446,718,277 - 46,917,321 (+)NCBI
RefSeq Acc Id: XM_039091931   ⟹   XP_038947859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,473 - 51,120,972 (+)NCBI
mRatBN7.21446,718,277 - 46,917,321 (+)NCBI
RefSeq Acc Id: XM_039091932   ⟹   XP_038947860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,471 - 51,094,269 (+)NCBI
mRatBN7.21446,718,277 - 46,888,015 (+)NCBI
RefSeq Acc Id: XM_039091936   ⟹   XP_038947864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,966,741 - 51,120,972 (+)NCBI
mRatBN7.21446,756,987 - 46,917,326 (+)NCBI
RefSeq Acc Id: XM_039091937   ⟹   XP_038947865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,471 - 51,040,000 (+)NCBI
mRatBN7.21446,718,277 - 46,836,350 (+)NCBI
RefSeq Acc Id: XM_039091938   ⟹   XP_038947866
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,470 - 51,035,337 (+)NCBI
mRatBN7.21446,718,277 - 46,831,686 (+)NCBI
RefSeq Acc Id: XR_005492952
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,471 - 51,110,226 (+)NCBI
mRatBN7.21446,718,277 - 46,906,584 (+)NCBI
RefSeq Acc Id: XR_005492953
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,471 - 51,075,055 (+)NCBI
mRatBN7.21446,718,277 - 46,871,404 (+)NCBI
RefSeq Acc Id: XR_010057366
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81450,921,472 - 51,082,628 (+)NCBI
RefSeq Acc Id: NP_001100686   ⟸   NM_001107216
- UniProtKB: A0A0G2K7I9 (UniProtKB/TrEMBL),   A6IJD8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000035496   ⟸   ENSRNOT00000031638
Ensembl Acc Id: ENSRNOP00000070433   ⟸   ENSRNOT00000082599
Ensembl Acc Id: ENSRNOP00000071296   ⟸   ENSRNOT00000090271
Ensembl Acc Id: ENSRNOP00000074225   ⟸   ENSRNOT00000086646
RefSeq Acc Id: XP_038947857   ⟸   XM_039091929
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038947855   ⟸   XM_039091927
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038947858   ⟸   XM_039091930
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038947859   ⟸   XM_039091931
- Peptide Label: isoform X3
- UniProtKB: A0A0G2K7I9 (UniProtKB/TrEMBL),   A6IJD8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947860   ⟸   XM_039091932
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038947865   ⟸   XM_039091937
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038947866   ⟸   XM_039091938
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038947864   ⟸   XM_039091936
- Peptide Label: isoform X5
Ensembl Acc Id: ENSRNOP00000103220   ⟸   ENSRNOT00000164131
Protein Domains
Arf-GAP   PH   Ras-associating   Rho-GAP   SAM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7I9-F1-model_v2 AlphaFold A0A0G2K7I9 1-1671 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306452 AgrOrtholog
BioCyc Gene G2FUF-15678 BioCyc
Ensembl Genes ENSRNOG00000056826 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082599 ENTREZGENE
  ENSRNOT00000082599.2 UniProtKB/TrEMBL
  ENSRNOT00000086646 ENTREZGENE
  ENSRNOT00000086646.2 UniProtKB/TrEMBL
  ENSRNOT00000164131 ENTREZGENE
Gene3D-CATH 1.10.150.50 UniProtKB/TrEMBL
  1.10.220.150 UniProtKB/TrEMBL
  1.10.555.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
InterPro Arf-Rho-GAP_ANK-PH_domain UniProtKB/TrEMBL
  ArfGAP UniProtKB/TrEMBL
  ARFGAP/RecO UniProtKB/TrEMBL
  ArfGAP_dom_sf UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Ras-assoc UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_ARAP UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM_type UniProtKB/TrEMBL
KEGG Report rno:305367 UniProtKB/TrEMBL
NCBI Gene 305367 ENTREZGENE
PANTHER ARF-GAP WITH RHO-GAP DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C UniProtKB/TrEMBL
Pfam ArfGap UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  PF00788 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
PhenoGen Arap2 PhenoGen
PRINTS REVINTRACTNG UniProtKB/TrEMBL
PROSITE ARFGAP UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  PS50200 UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
RatGTEx ENSRNOG00000056826 RatGTEx
SMART ArfGap UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
  Rho_GAP UniProtKB/TrEMBL
  SAM_homology UniProtKB/TrEMBL
  SSF57863 UniProtKB/TrEMBL
UniProt A0A096MK16 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2K7I9 ENTREZGENE, UniProtKB/TrEMBL
  A6IJD8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-15 Arap2  ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2  Centd1  centaurin, delta 1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Centd1  centaurin, delta 1   Centd1_predicted  centaurin, delta 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Centd1_predicted  centaurin, delta 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED