Gene: Sacs (sacsin molecular chaperone) Rattus norvegicus
Symbol: Sacs
Name: sacsin molecular chaperone
Description: ENCODES a protein that exhibits chaperone binding (ortholog); Hsp70 protein binding (ortholog); proteasome binding (ortholog); INVOLVED IN negative regulation of inclusion body assembly (ortholog); ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy (ortholog); autosomal recessive limb-girdle muscular dystrophy type 2C (ortholog); Charlevoix-Saguenay spastic ataxia (ortholog); FOUND IN cytoplasm (ortholog); mitochondrion (ortholog); nucleus (ortholog); INTERACTS WITH 4-amino-2,6-dinitrotoluene; bisphenol A; indole-3-methanol
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC290301; LOC305940; RGD1305416; sacsin; similar to RIKEN cDNA E130115J16; spastic ataxia of Charlevoix-Saguenay (sacsin)
Homo sapiens (human) : SACS (sacsin molecular chaperone)  HGNC  Alliance
Mus musculus (house mouse) : Sacs (sacsin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sacs (sacsin molecular chaperone)
Pan paniscus (bonobo/pygmy chimpanzee) : SACS (sacsin molecular chaperone)
Canis lupus familiaris (dog) : SACS (sacsin molecular chaperone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sacs (sacsin molecular chaperone)
Sus scrofa (pig) : SACS (sacsin molecular chaperone)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01541,448,078 - 41,530,412 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01545,255,280 - 45,338,141 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41540,297,202 - 40,344,605 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11540,315,190 - 40,359,066 (+)NCBI
Celera1534,984,356 - 35,069,050 (+)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Sacs
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307281
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE