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Gene: Lrat (lecithin retinol acyltransferase) Rattus norvegicus
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Symbol: Lrat
Name: lecithin retinol acyltransferase
Description: Exhibits phosphatidylcholine-retinol O-acyltransferase activity; retinoic acid binding activity; and retinol binding activity. Involved in response to retinoic acid; response to vitamin A; and retinoid metabolic process. Localizes to the multivesicular body; perinuclear region of cytoplasm; and rough endoplasmic reticulum. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 14 and retinitis pigmentosa. Orthologous to human LRAT (lecithin retinol acyltransferase); PARTICIPATES IN altered retinoid cycle metabolic pathway; retinitis pigmentosa pathway; retinoic acid metabolic pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase); lecithin-retinol acyltransferase; lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase); phosphatidylcholine--retinol O-acyltransferase
Orthologs:
Homo sapiens (human) : LRAT (lecithin retinol acyltransferase)  HGNC  Alliance
Mus musculus (house mouse) : Lrat (lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrat (lecithin retinol acyltransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : LRAT (lecithin retinol acyltransferase)
Canis lupus familiaris (dog) : LRAT (lecithin retinol acyltransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrat (lecithin retinol acyltransferase)
Sus scrofa (pig) : LRAT (lecithin retinol acyltransferase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02181,896,304 - 181,905,366 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02201,310,924 - 201,319,986 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42174,636,382 - 174,645,444 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12174,586,488 - 174,595,550 (-)NCBI
Celera2162,290,825 - 162,299,887 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lrat
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68362
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.