Gene: Dpyd (dihydropyrimidine dehydrogenase) Rattus norvegicus
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Symbol: Dpyd
Name: dihydropyrimidine dehydrogenase
Description: ENCODES a protein that exhibits dihydropyrimidine dehydrogenase (NADP+) activity; dihydrouracil dehydrogenase (NAD+) activity; FAD binding; INVOLVED IN aging; circadian rhythm; pyrimidine nucleobase catabolic process; PARTICIPATES IN pyrimidine metabolic pathway; beta-alanine metabolic pathway; beta-ureidopropionase deficiency pathway; ASSOCIATED WITH Colorectal Neoplasms; liver disease; Sarcoma, Yoshida; FOUND IN cytosol; cytoplasm (ortholog); INTERACTS WITH 1-benzylpiperazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DHPDHase; dihydropyrimidine dehydrogenase [NADP(+)]; dihydropyrimidine dehydrogenase [NADP+]; dihydrothymine dehydrogenase; dihydrouracil dehydrogenase; DPD
Orthologs:
Homo sapiens (human) : DPYD (dihydropyrimidine dehydrogenase)  HGNC  Alliance
Mus musculus (house mouse) : Dpyd (dihydropyrimidine dehydrogenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dpyd (dihydropyrimidine dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : DPYD (dihydropyrimidine dehydrogenase)
Canis lupus familiaris (dog) : DPYD (dihydropyrimidine dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dpyd (dihydropyrimidine dehydrogenase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02221,823,692 - 222,694,627 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02240,072,322 - 240,744,042 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02239,874,415 - 240,000,215 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42214,931,901 - 215,818,809 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12214,894,962 - 215,781,871 (+)NCBI
Celera2199,080,477 - 199,932,183 (+)NCBICelera
Cytogenetic Map2q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dpyd
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621218
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-08-14
Status: ACTIVE