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Gene: Crnkl1 (crooked neck pre-mRNA splicing factor 1) Rattus norvegicus
Symbol: Crnkl1
Name: crooked neck pre-mRNA splicing factor 1
Description: Predicted to have RNA binding activity. Involved in cellular response to brain-derived neurotrophic factor stimulus; cellular response to leukemia inhibitory factor; and cerebral cortex development. Predicted to localize to the Prp19 complex; U2-type catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Human ortholog(s) of this gene implicated in basal cell carcinoma. Orthologous to human CRNKL1 (crooked neck pre-mRNA splicing factor 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Crn; Crn, crooked neck-like 1; Crn, crooked neck-like 1 (Drosophila); crooked neck homolog; crooked neck pre-mRNA splicing factor-like 1; crooked neck pre-mRNA splicing factor-like 1 (Drosophila); crooked neck protein; crooked neck-like 1 protein-like; crooked neck-like protein 1; crooked neck-like protein 1-like; LOC100360434; LOC100910202; MGC93283
Homo sapiens (human) : CRNKL1 (crooked neck pre-mRNA splicing factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Crnkl1 (crooked neck pre-mRNA splicing factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crnkl1 (crooked neck pre-mRNA splicing factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CRNKL1 (crooked neck pre-mRNA splicing factor 1)
Canis lupus familiaris (dog) : CRNKL1 (crooked neck pre-mRNA splicing factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crnkl1 (crooked neck pre-mRNA splicing factor 1)
Sus scrofa (pig) : CRNKL1 (crooked neck pre-mRNA splicing factor 1)
more info ...
Related Pseudogenes: Crnkl1-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0618,349,226 - 18,351,540 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0628,249,112 - 28,251,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43134,538,940 - 134,554,660 (-)NCBIRGSC3.4rn4RGSC3.4
Celera6957,687 - 960,001 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Crnkl1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620507
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.