Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Crnkl1 (crooked neck pre-mRNA splicing factor 1) Rattus norvegicus
Analyze
Symbol: Crnkl1
Name: crooked neck pre-mRNA splicing factor 1
Description: Predicted to have RNA binding activity. Involved in cellular response to brain-derived neurotrophic factor stimulus; cellular response to leukemia inhibitory factor; and cerebral cortex development. Predicted to localize to the Prp19 complex; U2-type catalytic step 2 spliceosome; and post-mRNA release spliceosomal complex. Human ortholog(s) of this gene implicated in basal cell carcinoma. Orthologous to human CRNKL1 (crooked neck pre-mRNA splicing factor 1); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Crn; Crn, crooked neck-like 1; Crn, crooked neck-like 1 (Drosophila); crooked neck homolog; crooked neck pre-mRNA splicing factor-like 1; crooked neck pre-mRNA splicing factor-like 1 (Drosophila); crooked neck protein; crooked neck-like 1 protein-like; crooked neck-like protein 1; crooked neck-like protein 1-like; LOC100360434; LOC100910202; MGC93283
Orthologs:
Homo sapiens (human) : CRNKL1 (crooked neck pre-mRNA splicing factor 1)  HGNC  Alliance
Mus musculus (house mouse) : Crnkl1 (crooked neck pre-mRNA splicing factor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crnkl1 (crooked neck pre-mRNA splicing factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CRNKL1 (crooked neck pre-mRNA splicing factor 1)
Canis lupus familiaris (dog) : CRNKL1 (crooked neck pre-mRNA splicing factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crnkl1 (crooked neck pre-mRNA splicing factor 1)
Sus scrofa (pig) : CRNKL1 (crooked neck pre-mRNA splicing factor 1)
more info ...
Related Pseudogenes: Crnkl1-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0618,349,226 - 18,351,540 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0628,249,112 - 28,251,426 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43134,538,940 - 134,554,660 (-)NCBIRGSC3.4rn4RGSC3.4
Celera6957,687 - 960,001 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Crnkl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620507
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.