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Gene: Zic2 (Zic family member 2) Rattus norvegicus
Symbol: Zic2
Name: Zic family member 2
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and chromatin DNA binding activity. Predicted to be involved in several processes, including nervous system development; regulation of transcription, DNA-templated; and visual perception. Predicted to localize to the cytoplasm and nuclear body. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 5. Orthologous to human ZIC2 (Zic family member 2); PARTICIPATES IN Hedgehog signaling pathway; INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC361096; Zic family member 2 (odd-paired homolog, Drosophila); zinc finger protein of the cerebellum 2; zinc finger protein ZIC 2
Homo sapiens (human) : ZIC2 (Zic family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Zic2 (zinc finger protein of the cerebellum 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zic2 (Zic family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZIC2 (Zic family member 2)
Canis lupus familiaris (dog) : ZIC2 (Zic family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zic2 (Zic family member 2)
Sus scrofa (pig) : ZIC2 (Zic family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.015108,908,366 - 108,913,812 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15108,908,607 - 108,912,737 (+)Ensembl
Rnor_5.015112,296,472 - 112,301,371 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415107,609,060 - 107,613,169 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.115107,624,839 - 107,629,424 (+)NCBI
Celera1598,350,700 - 98,355,483 (+)NCBICelera
Cytogenetic Map15q25NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Zic2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311174
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.