Gpr39 (G protein-coupled receptor 39)

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Gene: Gpr39 (G protein-coupled receptor 39) Rattus norvegicus

Analyze

Symbol:

Gpr39

Name:

G protein-coupled receptor 39

RGD ID:

1306745

Description:

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within several processes, including adult feeding behavior; cellular response to zinc ion; and regulation of secretion. Predicted to be located in membrane. Orthologous to human GPR39 (G protein-coupled receptor 39); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

G-protein coupled receptor 39; LOC288995

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR39 (G protein-coupled receptor 39)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Gpr39 (G protein-coupled receptor 39)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr39 (G protein-coupled receptor 39)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR39 (G protein-coupled receptor 39)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR39 (G protein-coupled receptor 39)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr39 (G protein-coupled receptor 39)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR39 (G protein-coupled receptor 39)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr39 (G protein-coupled receptor 39)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	GPR39 (G protein-coupled receptor 39)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gpr39 (G protein-coupled receptor 39)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpr39 (G protein-coupled receptor 39)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	37,115,258 - 37,327,312 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	37,115,102 - 37,328,267 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	39,714,881 - 39,921,158 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	13	41,002,909 - 41,209,182 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	13	38,268,760 - 38,475,116 (+)	NCBI	Rnor_WKY
Rnor_6.0	13	42,008,642 - 42,220,737 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	42,008,842 - 42,009,738 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	47,119,931 - 47,328,375 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	38,181,953 - 38,400,282 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	38,196,195 - 38,414,321 (+)	NCBI
Celera	13	36,918,413 - 37,123,031 (+)	NCBI		Celera
Cytogenetic Map	13	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

calcitriol (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

dextran sulfate (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

furan (EXP)

gentamycin (EXP)

mercury dibromide (ISO)

methylmercury chloride (ISO)

nickel atom (ISO)

nickel sulfate (ISO)

paracetamol (EXP)

phenylmercury acetate (ISO)

potassium chromate (ISO)

rotenone (EXP,ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sotorasib (ISO)

sunitinib (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trametinib (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult feeding behavior (ISO)

cellular response to zinc ion (ISO)

cholesterol homeostasis (ISO)

diet induced thermogenesis (ISO)

establishment of localization in cell (ISO)

G protein-coupled receptor signaling pathway (IBA)

gastric acid secretion (ISO)

gastric emptying (ISO)

glucose homeostasis (ISO)

insulin secretion (ISO)

insulin secretion involved in cellular response to glucose stimulus (ISO)

negative regulation of gastric acid secretion (ISO)

neuron cellular homeostasis (ISO)

positive regulation of insulin secretion (ISO)

positive regulation of insulin secretion involved in cellular response to glucose stimulus (ISO)

positive regulation of MAP kinase activity (ISO)

positive regulation of release of sequestered calcium ion into cytosol (ISO)

regulation of cellular pH (ISO)

regulation of lipid metabolic process (ISO)

regulation of membrane potential (ISO)

release of sequestered calcium ion into cytosol (ISO)

Cellular Component

membrane (IEA)

Molecular Function

G protein-coupled receptor activity (IBA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:17030183	PMID:17488974	PMID:17885920	PMID:19213833	PMID:19213841	PMID:21784784	PMID:22441041	PMID:22992743	PMID:23133519	PMID:24333148	PMID:26375174	PMID:27106635
PMID:28270014	PMID:31904090

Genomics

Comparative Map Data

Gpr39
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	37,115,258 - 37,327,312 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	37,115,102 - 37,328,267 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	39,714,881 - 39,921,158 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	13	41,002,909 - 41,209,182 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	13	38,268,760 - 38,475,116 (+)	NCBI	Rnor_WKY
Rnor_6.0	13	42,008,642 - 42,220,737 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	42,008,842 - 42,009,738 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	47,119,931 - 47,328,375 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	38,181,953 - 38,400,282 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	38,196,195 - 38,414,321 (+)	NCBI
Celera	13	36,918,413 - 37,123,031 (+)	NCBI		Celera
Cytogenetic Map	13	q12	NCBI

GPR39
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	132,416,805 - 132,646,582 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	2	132,416,805 - 132,646,582 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	133,174,378 - 133,404,155 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	132,890,617 - 133,120,639 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	133,008,347 - 133,236,911	NCBI
Celera	2	126,889,417 - 127,119,426 (+)	NCBI		Celera
Cytogenetic Map	2	q21.2	NCBI
HuRef	2	125,167,784 - 125,397,791 (+)	NCBI		HuRef
CHM1_1	2	133,179,388 - 133,409,402 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	132,855,128 - 133,084,942 (+)	NCBI		T2T-CHM13v2.0

Gpr39
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	125,604,733 - 125,801,599 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	125,604,732 - 125,801,599 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	125,676,996 - 125,873,862 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	125,676,995 - 125,873,862 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	127,573,573 - 127,770,439 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	127,504,883 - 127,505,830 (+)	NCBI		MGSCv36	mm8
Celera	1	128,334,189 - 128,532,633 (+)	NCBI		Celera
Cytogenetic Map	1	E3	NCBI

Gpr39
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955440	47,652 - 239,206 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955440	46,648 - 235,644 (+)	NCBI	ChiLan1.0	ChiLan1.0

GPR39
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2B	136,509,316 - 136,510,431 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	2B	27,429,851 - 27,431,292 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

GPR39
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	19	35,385,835 - 35,585,953 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	19	35,385,829 - 35,586,507 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	19	35,617,325 - 35,815,657 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	19	36,821,160 - 37,020,836 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	19	36,821,312 - 37,021,482 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	19	35,468,606 - 35,669,165 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	19	35,630,016 - 35,829,194 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	19	36,849,888 - 37,048,076 (+)	NCBI		UU_Cfam_GSD_1.0

Gpr39
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	85,643,574 - 85,645,151 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936469	55,972,948 - 56,169,227 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936469	55,973,001 - 55,974,070 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR39
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	19,557,893 - 19,799,040 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	19,556,066 - 19,801,203 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	22,134,237 - 22,135,040 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	15	22,412,380 - 22,413,403 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Gpr39
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624732	31,801,512 - 32,045,229 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624732	31,801,512 - 32,045,271 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gpr39
953 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	86
Count of miRNA genes:	67
Interacting mature miRNAs:	72
Transcripts:	ENSRNOT00000038811
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738036	Lnnr4	Liver neoplastic nodule remodeling QTL 4	3.64		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	1	42356786	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
61339	Bp24	Blood pressure QTL 24		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	5994668	44807491	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	5994833	77046787	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	9313465	54313465	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	9313465	54313465	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	9831541	54831541	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	9831541	54831541	Rat
1300163	Cardf1	Cardiac cell morphology QTL 1	4.18		aorta morphology trait (VT:0000272)	artery lesion measurement (CMO:0000975)	13	11929449	45417941	Rat
2302275	Gluco37	Glucose level QTL 37	3.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	13	11929449	46193066	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	14915655	59915655	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	15158722	60158722	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	17694436	53050594	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	22301875	67301875	Rat
70170	Eae14	Experimental allergic encephalomyelitis QTL 14		0.0024	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	23203448	68203448	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	23692969	68692969	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	23692969	68692969	Rat
2303030	Bp327	Blood pressure QTL 327			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	30395351	41184251	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	31241331	58363171	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	31241331	93395974	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	32284471	77284471	Rat
61453	Pur1	Proteinuria QTL 1	18.06		urine total protein amount (VT:0000032)	urine protein level (CMO:0000591)	13	34535218	37415726	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	34535218	79535218	Rat
2292232	Pur16	Proteinuria QTL 16	17.2		urine total protein amount (VT:0000032)	urine protein level (CMO:0000591)	13	36155723	41961389	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	37262092	82262092	Rat

Markers in Region

D13Rat20

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	37,262,092 - 37,262,232 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	42,155,543 - 42,155,682	NCBI	Rnor6.0
Rnor_5.0	13	47,267,053 - 47,267,192	UniSTS	Rnor5.0
RGSC_v3.4	13	38,329,089 - 38,329,229	RGD	RGSC3.4
RGSC_v3.4	13	38,329,090 - 38,329,229	UniSTS	RGSC3.4
RGSC_v3.1	13	38,343,132 - 38,343,272	RGD
Celera	13	37,065,270 - 37,065,412	UniSTS
RH 2.0 Map	13	292.2	RGD
SHRSP x BN Map	13	8.0099	RGD
FHH x ACI Map	13	9.15	RGD
Cytogenetic Map	13	q11	UniSTS

D13Got4

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	37,140,037 - 37,140,206 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	42,033,420 - 42,033,588	NCBI	Rnor6.0
Rnor_5.0	13	47,144,709 - 47,144,877	UniSTS	Rnor5.0
RGSC_v3.4	13	38,206,730 - 38,206,899	RGD	RGSC3.4
RGSC_v3.4	13	38,206,731 - 38,206,899	UniSTS	RGSC3.4
RGSC_v3.1	13	38,220,773 - 38,220,942	RGD
Celera	13	36,943,193 - 36,943,351	UniSTS
RH 2.0 Map	13	285.0	RGD
Cytogenetic Map	13	q11	UniSTS

AI853408

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	37,326,758 - 37,326,876 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	42,220,184 - 42,220,301	NCBI	Rnor6.0
Rnor_5.0	13	47,327,822 - 47,327,939	UniSTS	Rnor5.0
RGSC_v3.4	13	38,399,729 - 38,399,846	UniSTS	RGSC3.4
Celera	13	37,122,478 - 37,122,595	UniSTS
Cytogenetic Map	13	q11	UniSTS

AU046866

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	37,263,179 - 37,263,410 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	42,156,630 - 42,156,860	NCBI	Rnor6.0
Rnor_5.0	13	47,268,140 - 47,268,370	UniSTS	Rnor5.0
RGSC_v3.4	13	38,330,177 - 38,330,407	UniSTS	RGSC3.4
Celera	13	37,066,360 - 37,066,590	UniSTS
Cytogenetic Map	13	q11	UniSTS

BF414576

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	37,318,807 - 37,318,899 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	42,212,233 - 42,212,324	NCBI	Rnor6.0
Rnor_5.0	13	47,319,871 - 47,319,962	UniSTS	Rnor5.0
RGSC_v3.4	13	38,391,778 - 38,391,869	UniSTS	RGSC3.4
Celera	13	37,114,527 - 37,114,618	UniSTS
RH 3.4 Map	19	396.93	UniSTS
Cytogenetic Map	13	q11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1		2	2		2				1
Low	2	26	46	39	14	39				34	33	11
Below cutoff		15	9		5		6	8	2		7		6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001114392	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BK005610	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474028	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000038811 ⟹ ENSRNOP00000036196

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	37,115,102 - 37,328,267 (+)	Ensembl
Rnor_6.0 Ensembl	13	42,008,842 - 42,009,738 (+)	Ensembl

RefSeq Acc Id:

NM_001100943 ⟹ NP_001094413

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	37,115,458 - 37,116,354 (+)	NCBI
Rnor_6.0	13	42,008,842 - 42,009,738 (+)	NCBI
Rnor_5.0	13	47,119,931 - 47,328,375 (+)	NCBI
RGSC_v3.4	13	38,181,953 - 38,400,282 (+)	RGD
Celera	13	36,918,613 - 36,919,509 (+)	NCBI

Sequence:

show sequence

ATGGCTTCATCCAGTGGCTCCAGCAACATCTGCTCCCGAGTCATCGATCACAGCCATGTCCCTG
AGTTCGAAGTGGCCACTTGGATCAAAATCACCCTCACCTTGGTGTACCTGATCGTCTTCGTGGT
AGGCATCTTGGGCAATAGCGTCACCATCCGGGTTACGCAGGTATTGCAGAAAAAGGGCTATTTG
CAGAAGGAGGTGACAGATCACATGATCAGTTTGGCTTGTTCAGATATCTTGGTCTTTTTGATTG
GCATGCCCATGGAGTTCTACAGCATCATCTGGAACCCCCTGACCACACCCAGCTATGCTCTGTC
CTGCAAGCTCCACACGTTCCTCTTTGAGACGTGTAGCTACGCCACATTGCTGCATGTGCTGACC
CTCAGCTTTGAGCGCTACATTGCCATTTGTCATCCCTTCAGATATAAGGACGTGTCTGGACCTT
GCCAGGTGAAACTGCTGATCGGCTTTGTATGGGTCACCTCCGCTCTGGTGGCACTGCCCTTGCT
CTTTGCCATGGGTATTGAGTACCCTCTGGCGAACGTCCCCACTCACAAGGGACTCAACTGTAAC
CTCTCTCGTACCCGCCACCACGATCATCCTGGAGACTCCAATATGTCCATCTGCACGAACCTCT
CCAGCCGTTGGGAGGTCTTCCAGTCCAGCATCTTTGGGGCCTTCGCTGTTTACCTGGTGGTCCT
GGTGTCTGTGGCTTTCATGTGTTGGAACATGATGAAAGTGCTAATGAAGAGCAAGCGGGGTACT
CTGGCAGGGACCGGACCACAGCTGCAGCTGCGGAAGTCAGAGAGTGAGGAGAGCCGGACAGCGA
GAAGACAGACCATCATATTCCTGAGTGAGTCTGGGTCGCGGGGAATTTTGGGCCCTTTGGCCTG
A

hide sequence

RefSeq Acc Id:

NM_001114392 ⟹ NP_001107864

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	37,115,258 - 37,327,312 (+)	NCBI
Rnor_6.0	13	42,008,642 - 42,220,737 (+)	NCBI
Rnor_5.0	13	47,119,931 - 47,328,375 (+)	NCBI
RGSC_v3.4	13	38,181,953 - 38,400,282 (+)	RGD
Celera	13	36,918,413 - 37,123,031 (+)	RGD

Sequence:

show sequence

TCGCGTCGCCAGGGATTCTAGGGTGAATTCTTCCAGGAAGTTTCGATGAGAGAGCCGAAAAACT
AAGTCACCCTTGGCCAGCCAACCACAGAGACAGAAATTGTTGCACCCACGCTGGTGAGTCGTGA
GGCTTCTTTGGGAGGCGGAAGAAAAGAAAGTGGAGACATTTGGGGACCTGGTGGTCAGGGTCTC
TCTTCCTCATGGCTTCATCCAGTGGCTCCAGCAACATCTGCTCCCGAGTCATCGATCACAGCCA
TGTCCCTGAGTTCGAAGTGGCCACTTGGATCAAAATCACCCTCACCTTGGTGTACCTGATCGTC
TTCGTGGTAGGCATCTTGGGCAATAGCGTCACCATCCGGGTTACGCAGGTATTGCAGAAAAAGG
GCTATTTGCAGAAGGAGGTGACAGATCACATGATCAGTTTGGCTTGTTCAGATATCTTGGTCTT
TTTGATTGGCATGCCCATGGAGTTCTACAGCATCATCTGGAACCCCCTGACCACACCCAGCTAT
GCTCTGTCCTGCAAGCTCCACACGTTCCTCTTTGAGACGTGTAGCTACGCCACATTGCTGCATG
TGCTGACCCTCAGCTTTGAGCGCTACATTGCCATTTGTCATCCCTTCAGATATAAGGACGTGTC
TGGACCTTGCCAGGTGAAACTGCTGATCGGCTTTGTATGGGTCACCTCCGCTCTGGTGGCACTG
CCCTTGCTCTTTGCCATGGGTATTGAGTACCCTCTGGCGAACGTCCCCACTCACAAGGGACTCA
ACTGTAACCTCTCTCGTACCCGCCACCACGATCATCCTGGAGACTCCAATATGTCCATCTGCAC
GAACCTCTCCAGCCGTTGGGAGGTCTTCCAGTCCAGCATCTTTGGGGCCTTCGCTGTTTACCTG
GTGGTCCTGGTGTCTGTGGCTTTCATGTGTTGGAACATGATGAAAGTGCTAATGAAGAGCAAGC
GGGGTACTCTGGCAGGGACCGGACCACAGCTGCAGCTGCGGAAGTCAGAGAGTGAGGAGAGCCG
GACAGCGAGAAGACAGACCATCATATTCCTGAGACTGATCGTGGTGACACTGGCCGTGTGTTGG
ATGCCAAATCAGATCCGACGGATCATGGCCGCAGCAAAACCCAAACATGACTGGACCAAGTCGT
ACTTCAAGGCGTACATGATCCTCCTCCCCTTCTCCGACACCTTCTTCTACCTCAGCTCCGTGGT
CAACCCTCTCCTCTACAACGTGTCTTCTCAGCAGTTCCGGAAGGTTTTCTGGCAGGTTCTCTGC
TGCCGGCTGACTCTGCAGCATGCCAACCAGGAGAAACAGCAGCGTGCCTACTTCAGCTCTACCA
AAAACAGCAGCCGCTCAGCCCGAAGCCCGCTCATCTTCCTAGCCTCCCGGCGTAGTAACTCTTC
CTCCCGGAGAACTAACAAGGTTTTCTTAAGCACTTTTCAGGCGGAGGCTAAGCCTCTAGAGGGC
GAGCACCAGCCCTTGAGTCCTGAGTCACCACAGACCGGCTCAGAGACCAAACCTGCTGGTTCCG
CCACAGAAAATAGTTTACAGGAGCAGGAAGTGTGAATGT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001094413	(Get FASTA)	NCBI Sequence Viewer
	NP_001107864	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	DAA06056	(Get FASTA)	NCBI Sequence Viewer
	EDL87968	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001107864 ⟸ NM_001114392
- Peptide Label:	isoform 1
- UniProtKB:	A0A8J8Y1V6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASSSGSSNICSRVIDHSHVPEFEVATWIKITLTLVYLIVFVVGILGNSVTIRVTQVLQKKGYL QKEVTDHMISLACSDILVFLIGMPMEFYSIIWNPLTTPSYALSCKLHTFLFETCSYATLLHVLT LSFERYIAICHPFRYKDVSGPCQVKLLIGFVWVTSALVALPLLFAMGIEYPLANVPTHKGLNCN LSRTRHHDHPGDSNMSICTNLSSRWEVFQSSIFGAFAVYLVVLVSVAFMCWNMMKVLMKSKRGT LAGTGPQLQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTKSYFK AYMILLPFSDTFFYLSSVVNPLLYNVSSQQFRKVFWQVLCCRLTLQHANQEKQQRAYFSSTKNS SRSARSPLIFLASRRSNSSSRRTNKVFLSTFQAEAKPLEGEHQPLSPESPQTGSETKPAGSATE NSLQEQEV hide sequence

RefSeq Acc Id:	NP_001094413 ⟸ NM_001100943
- Peptide Label:	isoform 2
- UniProtKB:	A6QR73 (UniProtKB/TrEMBL), E9PTT1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MASSSGSSNICSRVIDHSHVPEFEVATWIKITLTLVYLIVFVVGILGNSVTIRVTQVLQKKGYL QKEVTDHMISLACSDILVFLIGMPMEFYSIIWNPLTTPSYALSCKLHTFLFETCSYATLLHVLT LSFERYIAICHPFRYKDVSGPCQVKLLIGFVWVTSALVALPLLFAMGIEYPLANVPTHKGLNCN LSRTRHHDHPGDSNMSICTNLSSRWEVFQSSIFGAFAVYLVVLVSVAFMCWNMMKVLMKSKRGT LAGTGPQLQLRKSESEESRTARRQTIIFLSESGSRGILGPLA hide sequence

RefSeq Acc Id:

ENSRNOP00000036196 ⟸ ENSRNOT00000038811

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A6QR73-F1-model_v2	AlphaFold	A6QR73	1-298	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306745	AgrOrtholog
BioCyc Gene	G2FUF-18452	BioCyc
Ensembl Genes	ENSRNOG00000021586	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000036196	ENTREZGENE
	ENSRNOP00000036196.4	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038811	ENTREZGENE
	ENSRNOT00000038811.4	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	7TM_GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_supfam	UniProtKB/TrEMBL
KEGG Report	rno:288995	UniProtKB/TrEMBL
NCBI Gene	288995	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR 39	UniProtKB/TrEMBL
	G-PROTEIN COUPLED RECEPTOR 39	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PhenoGen	Gpr39	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	A0A8J8Y1V6	ENTREZGENE, UniProtKB/TrEMBL
	A6QR73	ENTREZGENE, UniProtKB/TrEMBL
	E9PTT1	ENTREZGENE
UniProt Secondary	E9PTT1	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Gpr39	G protein-coupled receptor 39	Gpr39_predicted	G protein-coupled receptor 39 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Gpr39_predicted	G protein-coupled receptor 39 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar