Symbol:
Brd2
Name:
bromodomain containing 2
RGD ID:
1303324
Description:
Predicted to enable several functions, including chromatin binding activity; histone reader activity; and lysine-acetylated histone binding activity. Predicted to be involved in several processes, including chromatin looping; nucleosome assembly; and positive regulation of T-helper 17 cell lineage commitment. Predicted to act upstream of or within neural tube closure. Predicted to be located in cytoplasm and nuclear speck. Predicted to be active in chromatin and nucleus. Human ortholog(s) of this gene implicated in B-cell lymphoma; B-lymphoblastic leukemia/lymphoma; juvenile myoclonic epilepsy; and photosensitivity disease. Orthologous to human BRD2 (bromodomain containing 2); PARTICIPATES IN histone modification pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
bromodomain-containing 2; bromodomain-containing protein 2; LOC108348112; Ring3
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
BRD2 (bromodomain containing 2) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):
Brd2 (bromodomain containing 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Brd2 (bromodomain containing 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
BRD2 (bromodomain containing 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
BRD2 (bromodomain containing 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Brd2 (bromodomain containing 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
BRD2 (bromodomain containing 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
BRD2 (bromodomain containing 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Brd2 (bromodomain containing 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
LGALS8 (galectin 8) HGNC
OMA
Alliance orthologs 3
Homo sapiens (human):
BRD2 (bromodomain containing 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Brd2 (bromodomain containing 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
brd2a (bromodomain containing 2a)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
brd2b (bromodomain containing 2b)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|PANTHER|PhylomeDB|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
BDF1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Caenorhabditis elegans (roundworm):
bet-1
Alliance
DIOPT (Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Drosophila melanogaster (fruit fly):
fs(1)h
Alliance
DIOPT (Hieranoid|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):
BDF2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|SonicParanoid)
Drosophila melanogaster (fruit fly):
tbrd-1
Alliance
DIOPT (Ensembl Compara|InParanoid|PANTHER)
Xenopus tropicalis (tropical clawed frog):
brd2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Is Marker For:
QTLs:
Tcs1
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 20 4,728,282 - 4,737,286 (+) NCBI GRCr8 mRatBN7.2 20 4,727,078 - 4,735,389 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 20 4,728,151 - 4,735,388 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 20 5,480,415 - 5,487,612 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 20 4,842,158 - 4,849,355 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 20 5,323,436 - 5,330,635 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 20 3,910,555 - 3,921,074 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 5,262,120 - 5,269,337 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 3,910,555 - 3,917,426 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 20 7,323,184 - 7,330,398 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 20 4,864,606 - 4,871,813 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 20 4,864,832 - 4,872,040 (+) NCBI Celera 20 6,328,831 - 6,336,038 (+) NCBI Celera Cytogenetic Map 20 p12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Only show annotations with direct experimental evidence (0 objects hidden)
Brd2 Rat (+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of BRD2 mRNA] CTD PMID:31150632 Brd2 Rat (1->4)-beta-D-glucan multiple interactions ISO Brd2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of BRD2 mRNA CTD PMID:36331819 Brd2 Rat (S)-nicotine increases expression ISO Brd2 (Mus musculus) 6480464 Nicotine results in increased expression of BRD2 mRNA CTD PMID:33640489 Brd2 Rat 17beta-estradiol multiple interactions ISO BRD2 (Homo sapiens) 6480464 3 more ... CTD PMID:11179685 Brd2 Rat 17beta-estradiol increases expression ISO Brd2 (Mus musculus) 6480464 Estradiol results in increased expression of BRD2 mRNA CTD PMID:39298647 Brd2 Rat 17beta-estradiol increases expression ISO BRD2 (Homo sapiens) 6480464 Estradiol results in increased expression of BRD2 mRNA CTD PMID:11179685 Brd2 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO BRD2 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of BRD2 mRNA] CTD PMID:11179685 Brd2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of BRD2 mRNA CTD PMID:33387578 Brd2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Brd2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of BRD2 mRNA CTD PMID:20702594 and PMID:21570461 Brd2 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of BRD2 mRNA CTD PMID:34747641 Brd2 Rat 2,3,7,8-Tetrachlorodibenzofuran affects expression ISO Brd2 (Mus musculus) 6480464 2 more ... CTD PMID:20702594 Brd2 Rat 2,4-dinitrotoluene affects expression EXP 6480464 2 and 4-dinitrotoluene affects the expression of BRD2 mRNA CTD PMID:21346803 Brd2 Rat 2-hydroxypropanoic acid increases expression ISO BRD2 (Homo sapiens) 6480464 Lactic Acid results in increased expression of BRD2 mRNA CTD PMID:30851411 Brd2 Rat 3,3'-diindolylmethane multiple interactions ISO BRD2 (Homo sapiens) 6480464 3 and 3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of BRD2 mRNA] CTD PMID:11179685 Brd2 Rat 4,4'-sulfonyldiphenol increases expression ISO Brd2 (Mus musculus) 6480464 bisphenol S results in increased expression of BRD2 mRNA CTD PMID:39298647 Brd2 Rat 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO BRD2 (Homo sapiens) 6480464 BRD2 mutant form inhibits the reaction [6-chloro-2 more ... CTD PMID:26212199 Brd2 Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of BRD2 mRNA CTD PMID:22504374 and PMID:30047161 Brd2 Rat acrolein multiple interactions ISO BRD2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BRD2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of BRD2 mRNA CTD PMID:32699268 Brd2 Rat acrylamide increases expression ISO BRD2 (Homo sapiens) 6480464 Acrylamide results in increased expression of BRD2 mRNA CTD PMID:32763439 Brd2 Rat afimoxifene decreases response to substance ISO BRD2 (Homo sapiens) 6480464 BRD2 results in decreased susceptibility to afimoxifene CTD PMID:21233418 Brd2 Rat aflatoxin B1 increases expression ISO Brd2 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of BRD2 mRNA CTD PMID:19770486 Brd2 Rat alpha-pinene multiple interactions ISO BRD2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BRD2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of BRD2 mRNA CTD PMID:32699268 Brd2 Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of BRD2 mRNA CTD PMID:30047161 Brd2 Rat amphetamine decreases expression EXP 6480464 Amphetamine results in decreased expression of BRD2 mRNA CTD PMID:30779732 Brd2 Rat aristolochic acid A increases expression ISO BRD2 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of BRD2 mRNA CTD PMID:33212167 Brd2 Rat azoxystrobin increases expression ISO BRD2 (Homo sapiens) 6480464 azoxystrobin results in increased expression of BRD2 mRNA CTD PMID:33512557 Brd2 Rat benzatropine multiple interactions ISO BRD2 (Homo sapiens) 6480464 [Cuprizone co-treated with Benztropine] results in decreased expression of BRD2 protein CTD PMID:34122009 Brd2 Rat benzo[a]pyrene increases expression ISO Brd2 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of BRD2 mRNA CTD PMID:19770486 and PMID:20504355 Brd2 Rat benzo[a]pyrene diol epoxide I increases expression ISO BRD2 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 Brd2 Rat Benzo[k]fluoranthene decreases expression ISO Brd2 (Mus musculus) 6480464 benzo(k)fluoranthene results in decreased expression of BRD2 mRNA CTD PMID:26377693 Brd2 Rat bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of BRD2 mRNA CTD PMID:25181051 more ... Brd2 Rat bisphenol A multiple interactions ISO BRD2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of BRD2 gene CTD PMID:31601247 Brd2 Rat bisphenol A decreases expression ISO Brd2 (Mus musculus) 6480464 bisphenol A results in decreased expression of BRD2 mRNA CTD PMID:33221593 Brd2 Rat bisphenol A affects expression ISO BRD2 (Homo sapiens) 6480464 bisphenol A affects the expression of BRD2 mRNA CTD PMID:30903817 Brd2 Rat bisphenol A increases expression ISO BRD2 (Homo sapiens) 6480464 bisphenol A results in increased expression of BRD2 mRNA CTD PMID:29275510 Brd2 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of BRD2 gene CTD PMID:28505145 Brd2 Rat cadmium dichloride decreases expression ISO BRD2 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of BRD2 mRNA CTD PMID:25596134 Brd2 Rat caffeine decreases phosphorylation ISO BRD2 (Homo sapiens) 6480464 Caffeine results in decreased phosphorylation of BRD2 protein CTD PMID:35688186 Brd2 Rat CGP 52608 multiple interactions ISO BRD2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to BRD2 gene] CTD PMID:28238834 Brd2 Rat chloroacetaldehyde affects expression ISO BRD2 (Homo sapiens) 6480464 chloroacetaldehyde affects the expression of BRD2 mRNA CTD PMID:25596134 Brd2 Rat chloropicrin increases expression ISO BRD2 (Homo sapiens) 6480464 chloropicrin results in increased expression of BRD2 mRNA CTD PMID:26352163 Brd2 Rat cidofovir anhydrous decreases expression ISO BRD2 (Homo sapiens) 6480464 Cidofovir results in decreased expression of BRD2 mRNA CTD PMID:25596134 Brd2 Rat cisplatin increases expression ISO BRD2 (Homo sapiens) 6480464 Cisplatin results in increased expression of BRD2 mRNA CTD PMID:19561079 and PMID:38498338 Brd2 Rat cisplatin decreases expression ISO Brd2 (Mus musculus) 6480464 Cisplatin results in decreased expression of BRD2 mRNA CTD PMID:21151649 Brd2 Rat cisplatin decreases expression ISO BRD2 (Homo sapiens) 6480464 Cisplatin results in decreased expression of BRD2 mRNA CTD PMID:25596134 Brd2 Rat clodronic acid decreases expression ISO BRD2 (Homo sapiens) 6480464 Clodronic Acid results in decreased expression of BRD2 mRNA CTD PMID:25596134 Brd2 Rat clofibrate multiple interactions ISO Brd2 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of BRD2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of BRD2 mRNA] CTD PMID:17585979 Brd2 Rat cobalt dichloride increases expression ISO BRD2 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of BRD2 mRNA CTD PMID:19320972 Brd2 Rat copper(II) sulfate increases expression ISO BRD2 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of BRD2 mRNA CTD PMID:19549813 Brd2 Rat coumarin increases phosphorylation ISO BRD2 (Homo sapiens) 6480464 coumarin results in increased phosphorylation of BRD2 protein CTD PMID:35688186 Brd2 Rat Cuprizon multiple interactions ISO BRD2 (Homo sapiens) 6480464 [Cuprizone co-treated with Benztropine] results in decreased expression of BRD2 protein CTD PMID:34122009 Brd2 Rat cyclosporin A increases expression ISO BRD2 (Homo sapiens) 6480464 Cyclosporine results in increased expression of BRD2 mRNA CTD PMID:25562108 and PMID:25596134 Brd2 Rat DDE decreases expression ISO BRD2 (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of BRD2 mRNA CTD PMID:38568856 Brd2 Rat deguelin increases expression ISO BRD2 (Homo sapiens) 6480464 deguelin results in increased expression of BRD2 mRNA CTD PMID:33512557 Brd2 Rat diazinon increases methylation ISO BRD2 (Homo sapiens) 6480464 Diazinon results in increased methylation of BRD2 gene CTD PMID:22964155 Brd2 Rat Dibutyl phosphate affects expression ISO BRD2 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of BRD2 mRNA CTD PMID:37042841 Brd2 Rat diethyl malate increases expression ISO BRD2 (Homo sapiens) 6480464 diethyl malate results in increased expression of BRD2 mRNA CTD PMID:38498338 Brd2 Rat diethylstilbestrol decreases expression ISO BRD2 (Homo sapiens) 6480464 Diethylstilbestrol results in decreased expression of BRD2 mRNA CTD PMID:36621641 Brd2 Rat dioxygen decreases expression ISO BRD2 (Homo sapiens) 6480464 Oxygen deficiency results in decreased expression of BRD2 mRNA CTD PMID:25596134 Brd2 Rat dioxygen increases expression ISO BRD2 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of BRD2 CTD PMID:27292261 Brd2 Rat doxorubicin decreases expression ISO BRD2 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of BRD2 mRNA CTD PMID:29803840 Brd2 Rat doxorubicin decreases expression ISO Brd2 (Mus musculus) 6480464 Doxorubicin results in decreased expression of BRD2 mRNA CTD PMID:19277126 Brd2 Rat elemental selenium increases expression ISO BRD2 (Homo sapiens) 6480464 Selenium results in increased expression of BRD2 mRNA CTD PMID:19244175 Brd2 Rat elemental selenium multiple interactions ISO BRD2 (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of BRD2 mRNA CTD PMID:19244175 Brd2 Rat epoxiconazole increases expression ISO Brd2 (Mus musculus) 6480464 epoxiconazole results in increased expression of BRD2 mRNA CTD PMID:35436446 Brd2 Rat ethanol multiple interactions ISO Brd2 (Mus musculus) 6480464 Ethanol affects the expression of and affects the splicing of BRD2 mRNA CTD PMID:30319688 Brd2 Rat fenofibrate decreases expression EXP 6480464 Fenofibrate results in decreased expression of BRD2 mRNA CTD PMID:25596134 Brd2 Rat fenthion increases expression ISO Brd2 (Mus musculus) 6480464 Fenthion results in increased expression of BRD2 mRNA CTD PMID:34813904 Brd2 Rat flutamide increases expression EXP 6480464 Flutamide results in increased expression of BRD2 mRNA CTD PMID:24136188 Brd2 Rat folic acid increases expression ISO Brd2 (Mus musculus) 6480464 Folic Acid results in increased expression of BRD2 mRNA CTD PMID:25629700 Brd2 Rat FR900359 affects phosphorylation ISO BRD2 (Homo sapiens) 6480464 FR900359 affects the phosphorylation of BRD2 protein CTD PMID:37730182 Brd2 Rat fulvestrant multiple interactions ISO BRD2 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of BRD2 gene CTD PMID:31601247 Brd2 Rat furan increases expression ISO Brd2 (Mus musculus) 6480464 furan results in increased expression of BRD2 mRNA CTD PMID:24183702 Brd2 Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of BRD2 mRNA CTD PMID:22061828 Brd2 Rat gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of BRD2 mRNA CTD PMID:33387578 Brd2 Rat ifosfamide decreases expression ISO BRD2 (Homo sapiens) 6480464 Ifosfamide results in decreased expression of BRD2 mRNA CTD PMID:25596134 Brd2 Rat inulin multiple interactions ISO Brd2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of BRD2 mRNA CTD PMID:36331819 Brd2 Rat iron dichloride increases expression ISO BRD2 (Homo sapiens) 6480464 ferrous chloride results in increased expression of BRD2 mRNA CTD PMID:35984750 Brd2 Rat ivermectin decreases expression ISO BRD2 (Homo sapiens) 6480464 Ivermectin results in decreased expression of BRD2 protein CTD PMID:32959892 Brd2 Rat leflunomide decreases expression ISO BRD2 (Homo sapiens) 6480464 leflunomide results in decreased expression of BRD2 mRNA CTD PMID:28988120 Brd2 Rat lipopolysaccharide increases expression ISO Brd2 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of BRD2 mRNA and Lipopolysaccharides results in increased expression of BRD2 protein CTD PMID:26349765 Brd2 Rat metformin affects expression EXP 6480464 Metformin affects the expression of BRD2 mRNA CTD PMID:25596134 Brd2 Rat methamphetamine increases expression ISO Brd2 (Mus musculus) 6480464 Methamphetamine results in increased expression of BRD2 mRNA CTD PMID:26307267 Brd2 Rat methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of BRD2 mRNA CTD PMID:30467583 Brd2 Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of BRD2 mRNA CTD PMID:22504374 and PMID:30047161 Brd2 Rat methotrexate affects expression ISO Brd2 (Mus musculus) 6480464 Methotrexate affects the expression of BRD2 mRNA CTD PMID:18502557 Brd2 Rat methyl methanesulfonate increases expression ISO BRD2 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of BRD2 mRNA CTD PMID:23649840 Brd2 Rat methylisothiazolinone increases expression ISO BRD2 (Homo sapiens) 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of BRD2 mRNA CTD PMID:31629900 Brd2 Rat methylmercury chloride increases expression ISO BRD2 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of BRD2 mRNA CTD PMID:28001369 Brd2 Rat N-(6-acetamidohexyl)acetamide multiple interactions ISO Brd2 (Mus musculus) 6480464 hexamethylene bisacetamide inhibits the reaction [BRD2 protein binds to SRM promoter] CTD PMID:26941288 Brd2 Rat N-methylformamide increases expression ISO Brd2 (Mus musculus) 6480464 methylformamide analog results in increased expression of BRD2 mRNA and methylformamide results in increased expression of BRD2 mRNA CTD PMID:17040096 Brd2 Rat nickel sulfate decreases expression ISO BRD2 (Homo sapiens) 6480464 nickel sulfate results in decreased expression of BRD2 mRNA CTD PMID:18651567 Brd2 Rat nicotine increases expression ISO Brd2 (Mus musculus) 6480464 Nicotine results in increased expression of BRD2 mRNA CTD PMID:33640489 Brd2 Rat nitrates multiple interactions ISO Brd2 (Mus musculus) 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of BRD2 mRNA CTD PMID:35964746 Brd2 Rat ozone multiple interactions ISO BRD2 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BRD2 mRNA more ... CTD PMID:32699268 Brd2 Rat paracetamol increases expression ISO BRD2 (Homo sapiens) 6480464 Acetaminophen results in increased expression of BRD2 mRNA CTD PMID:21420995 more ... Brd2 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of BRD2 mRNA CTD PMID:33387578 Brd2 Rat paracetamol multiple interactions ISO Brd2 (Mus musculus) 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of BRD2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of BRD2 mRNA] CTD PMID:17585979 Brd2 Rat paracetamol affects expression ISO Brd2 (Mus musculus) 6480464 Acetaminophen affects the expression of BRD2 mRNA CTD PMID:17562736 Brd2 Rat pentachlorophenol increases expression ISO Brd2 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of BRD2 mRNA CTD PMID:23892564 Brd2 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Brd2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of BRD2 mRNA more ... CTD PMID:36331819 Brd2 Rat phenobarbital decreases expression ISO Brd2 (Mus musculus) 6480464 Phenobarbital results in decreased expression of BRD2 mRNA CTD PMID:19270015 Brd2 Rat phenobarbital affects expression ISO Brd2 (Mus musculus) 6480464 Phenobarbital affects the expression of BRD2 mRNA CTD PMID:23091169 Brd2 Rat picoxystrobin increases expression ISO BRD2 (Homo sapiens) 6480464 picoxystrobin results in increased expression of BRD2 mRNA CTD PMID:33512557 Brd2 Rat pirinixic acid increases expression ISO Brd2 (Mus musculus) 6480464 pirinixic acid results in increased expression of BRD2 mRNA CTD PMID:16985257 Brd2 Rat propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of BRD2 mRNA CTD PMID:30047161 Brd2 Rat pyrimidines decreases splicing ISO BRD2 (Homo sapiens) 6480464 Pyrimidines results in decreased splicing of BRD2 mRNA CTD PMID:25281741 Brd2 Rat quercetin increases expression ISO BRD2 (Homo sapiens) 6480464 Quercetin results in increased expression of BRD2 mRNA CTD PMID:21632981 Brd2 Rat quinazolines decreases splicing ISO BRD2 (Homo sapiens) 6480464 Quinazolines results in decreased splicing of BRD2 mRNA CTD PMID:25281741 Brd2 Rat rac-lactic acid increases expression ISO BRD2 (Homo sapiens) 6480464 Lactic Acid results in increased expression of BRD2 mRNA CTD PMID:30851411 Brd2 Rat selenium atom increases expression ISO BRD2 (Homo sapiens) 6480464 Selenium results in increased expression of BRD2 mRNA CTD PMID:19244175 Brd2 Rat selenium atom multiple interactions ISO BRD2 (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of BRD2 mRNA CTD PMID:19244175 Brd2 Rat silicon dioxide increases expression ISO Brd2 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of BRD2 mRNA CTD PMID:19073995 Brd2 Rat sodium arsenite increases expression ISO BRD2 (Homo sapiens) 6480464 sodium arsenite results in increased expression of BRD2 mRNA CTD PMID:38568856 Brd2 Rat sodium fluoride increases expression ISO Brd2 (Mus musculus) 6480464 Sodium Fluoride results in increased expression of BRD2 mRNA CTD PMID:27862939 Brd2 Rat temozolomide increases expression ISO BRD2 (Homo sapiens) 6480464 Temozolomide results in increased expression of BRD2 mRNA CTD PMID:31758290 Brd2 Rat testosterone enanthate affects expression ISO BRD2 (Homo sapiens) 6480464 testosterone enanthate affects the expression of BRD2 mRNA CTD PMID:17440010 Brd2 Rat tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of BRD2 mRNA] CTD PMID:31150632 Brd2 Rat tetrachloromethane increases expression ISO Brd2 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of BRD2 mRNA CTD PMID:31919559 Brd2 Rat tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of BRD2 mRNA CTD PMID:31150632 Brd2 Rat thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of BRD2 mRNA CTD PMID:34492290 Brd2 Rat thiram increases expression ISO BRD2 (Homo sapiens) 6480464 Thiram results in increased expression of BRD2 mRNA CTD PMID:38568856 Brd2 Rat titanium dioxide increases methylation ISO Brd2 (Mus musculus) 6480464 titanium dioxide results in increased methylation of BRD2 promoter CTD PMID:35295148 Brd2 Rat titanium dioxide decreases methylation ISO Brd2 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of BRD2 gene and titanium dioxide results in decreased methylation of BRD2 promoter CTD PMID:35295148 Brd2 Rat trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of BRD2 mRNA CTD PMID:33387578 Brd2 Rat trichostatin A multiple interactions ISO Brd2 (Mus musculus) 6480464 trichostatin A inhibits the reaction [IL3 protein promotes the reaction [BRD2 protein binds to CISH promoter]] CTD PMID:25769527 Brd2 Rat trichostatin A affects localization ISO Brd2 (Mus musculus) 6480464 trichostatin A affects the localization of BRD2 protein CTD PMID:25769527 Brd2 Rat triphenyl phosphate affects expression ISO BRD2 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of BRD2 mRNA CTD PMID:37042841 Brd2 Rat triptonide increases expression ISO Brd2 (Mus musculus) 6480464 triptonide results in increased expression of BRD2 mRNA CTD PMID:33045310 Brd2 Rat triticonazole decreases expression EXP 6480464 triticonazole results in decreased expression of BRD2 mRNA CTD PMID:36084822 Brd2 Rat trovafloxacin increases expression ISO Brd2 (Mus musculus) 6480464 trovafloxacin results in increased expression of BRD2 mRNA CTD PMID:35537566 Brd2 Rat tungsten decreases expression ISO Brd2 (Mus musculus) 6480464 Tungsten results in decreased expression of BRD2 mRNA CTD PMID:30912803 Brd2 Rat tunicamycin increases expression ISO BRD2 (Homo sapiens) 6480464 Tunicamycin results in increased expression of BRD2 mRNA CTD PMID:22378314 Brd2 Rat valproic acid decreases expression ISO BRD2 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of BRD2 mRNA CTD PMID:29154799 Brd2 Rat valproic acid affects localization ISO Brd2 (Mus musculus) 6480464 Valproic Acid affects the localization of BRD2 protein CTD PMID:25769527 Brd2 Rat vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of BRD2 mRNA CTD PMID:19015723 Brd2 Rat vitamin E increases expression ISO BRD2 (Homo sapiens) 6480464 Vitamin E results in increased expression of BRD2 mRNA CTD PMID:19244175 Brd2 Rat vitamin E decreases expression ISO BRD2 (Homo sapiens) 6480464 Vitamin E results in decreased expression of BRD2 mRNA CTD PMID:19244175 Brd2 Rat vitamin E multiple interactions ISO BRD2 (Homo sapiens) 6480464 [Selenium co-treated with Vitamin E] results in decreased expression of BRD2 mRNA CTD PMID:19244175
(+)-schisandrin B (EXP) (1->4)-beta-D-glucan (ISO) (S)-nicotine (ISO) 17beta-estradiol (ISO) 2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO) 2,3,7,8-Tetrachlorodibenzofuran (ISO) 2,4-dinitrotoluene (EXP) 2-hydroxypropanoic acid (ISO) 3,3'-diindolylmethane (ISO) 4,4'-sulfonyldiphenol (ISO) 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide (ISO) 6-propyl-2-thiouracil (EXP) acrolein (ISO) acrylamide (ISO) afimoxifene (ISO) aflatoxin B1 (ISO) alpha-pinene (ISO) amitrole (EXP) amphetamine (EXP) aristolochic acid A (ISO) azoxystrobin (ISO) benzatropine (ISO) benzo[a]pyrene (ISO) benzo[a]pyrene diol epoxide I (ISO) Benzo[k]fluoranthene (ISO) bisphenol A (EXP,ISO) cadmium dichloride (ISO) caffeine (ISO) CGP 52608 (ISO) chloroacetaldehyde (ISO) chloropicrin (ISO) cidofovir anhydrous (ISO) cisplatin (ISO) clodronic acid (ISO) clofibrate (ISO) cobalt dichloride (ISO) copper(II) sulfate (ISO) coumarin (ISO) Cuprizon (ISO) cyclosporin A (ISO) DDE (ISO) deguelin (ISO) diazinon (ISO) Dibutyl phosphate (ISO) diethyl malate (ISO) diethylstilbestrol (ISO) dioxygen (ISO) doxorubicin (ISO) elemental selenium (ISO) epoxiconazole (ISO) ethanol (ISO) fenofibrate (EXP) fenthion (ISO) flutamide (EXP) folic acid (ISO) FR900359 (ISO) fulvestrant (ISO) furan (ISO) gentamycin (EXP) ifosfamide (ISO) inulin (ISO) iron dichloride (ISO) ivermectin (ISO) leflunomide (ISO) lipopolysaccharide (ISO) metformin (EXP) methamphetamine (ISO) methapyrilene (EXP) methimazole (EXP) methotrexate (ISO) methyl methanesulfonate (ISO) methylisothiazolinone (ISO) methylmercury chloride (ISO) N-(6-acetamidohexyl)acetamide (ISO) N-methylformamide (ISO) nickel sulfate (ISO) nicotine (ISO) nitrates (ISO) ozone (ISO) paracetamol (EXP,ISO) pentachlorophenol (ISO) perfluorooctane-1-sulfonic acid (ISO) phenobarbital (ISO) picoxystrobin (ISO) pirinixic acid (ISO) propiconazole (EXP) pyrimidines (ISO) quercetin (ISO) quinazolines (ISO) rac-lactic acid (ISO) selenium atom (ISO) silicon dioxide (ISO) sodium arsenite (ISO) sodium fluoride (ISO) temozolomide (ISO) testosterone enanthate (ISO) tetrachloromethane (EXP,ISO) thioacetamide (EXP) thiram (ISO) titanium dioxide (ISO) trichloroethene (EXP) trichostatin A (ISO) triphenyl phosphate (ISO) triptonide (ISO) triticonazole (EXP) trovafloxacin (ISO) tungsten (ISO) tunicamycin (ISO) valproic acid (ISO) vinclozolin (EXP) vitamin E (ISO)
Biological Process
chromatin looping (IEA,ISO,ISS) chromatin organization (IEA) chromatin remodeling (IBA) neural tube closure (IEA,ISO) nucleosome assembly (IEA,ISO,ISS) positive regulation of T-helper 17 cell lineage commitment (IEA,ISO,ISS) protein localization to chromatin (IEA,ISO,ISS) regulation of DNA-templated transcription (IBA) regulation of gene expression (IEA,ISO) regulation of transcription by RNA polymerase II (IEA,ISO,ISS)
1.
Change in nuclear-cytoplasmic localization of a double-bromodomain protein during proliferation and differentiation of mouse spinal cord and dorsal root ganglia.
Crowley T, etal., Brain Res Dev Brain Res 2004 Apr 19;149(2):93-101.
2.
Reproductive cycle regulation of nuclear import, euchromatic localization, and association with components of Pol II mediator of a mammalian double-bromodomain protein.
Crowley TE, etal., Mol Endocrinol 2002 Aug;16(8):1727-37.
3.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.
E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia.
Greenwald RJ, etal., Blood. 2004 Feb 15;103(4):1475-84. Epub 2003 Oct 16.
5.
Association of BRD2 polymorphisms with photoparoxysmal response.
Lorenz S, etal., Neurosci Lett. 2006 May 29;400(1-2):135-9. Epub 2006 Mar 3.
6.
Rat ISS GO annotations from MGI mouse gene data--August 2006
MGD data from the GO Consortium
7.
BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy.
Pal DK, etal., Am J Hum Genet 2003 Aug;73(2):261-70. Epub 2003 Jun 25.
8.
GOA pipeline
RGD automated data pipeline
9.
Data Import for Chemical-Gene Interactions
RGD automated import pipeline for gene-chemical interactions
10.
The bromodomain: From epigenome reader to druggable target.
Sanchez R, etal., Biochim Biophys Acta. 2014 Aug;1839(8):676-685. doi: 10.1016/j.bbagrm.2014.03.011. Epub 2014 Mar 28.
11.
BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy.
Segura MF, etal., Cancer Res. 2013 Oct 15;73(20):6264-76. doi: 10.1158/0008-5472.CAN-13-0122-T. Epub 2013 Aug 15.
12.
Brd2 disruption in mice causes severe obesity without Type 2 diabetes.
Wang F, etal., Biochem J. 2009 Dec 14;425(1):71-83. doi: 10.1042/BJ20090928.
Brd2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 20 4,728,282 - 4,737,286 (+) NCBI GRCr8 mRatBN7.2 20 4,727,078 - 4,735,389 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 20 4,728,151 - 4,735,388 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 20 5,480,415 - 5,487,612 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 20 4,842,158 - 4,849,355 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 20 5,323,436 - 5,330,635 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 20 3,910,555 - 3,921,074 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 5,262,120 - 5,269,337 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 3,910,555 - 3,917,426 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 20 7,323,184 - 7,330,398 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 20 4,864,606 - 4,871,813 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 20 4,864,832 - 4,872,040 (+) NCBI Celera 20 6,328,831 - 6,336,038 (+) NCBI Celera Cytogenetic Map 20 p12 NCBI
BRD2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 6 32,968,594 - 32,981,505 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 6 32,968,594 - 32,981,505 (+) Ensembl GRCh38 hg38 GRCh38 GRCh37 6 32,936,371 - 32,949,282 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 6 33,044,415 - 33,057,059 (+) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 6 33,044,414 - 33,057,059 NCBI Celera 6 34,485,349 - 34,498,195 (+) NCBI Celera Cytogenetic Map 6 p21.32 NCBI HuRef 6 32,678,978 - 32,691,818 (+) NCBI HuRef CHM1_1 6 32,937,242 - 32,950,091 (+) NCBI CHM1_1 T2T-CHM13v2.0 6 32,789,953 - 32,802,871 (+) NCBI T2T-CHM13v2.0
Brd2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 17 34,330,993 - 34,341,581 (-) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 17 34,330,997 - 34,341,608 (-) Ensembl GRCm39 Ensembl GRCm38 17 34,112,019 - 34,122,814 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 17 34,112,023 - 34,122,634 (-) Ensembl GRCm38 mm10 GRCm38 MGSCv37 17 34,248,964 - 34,258,692 (-) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 17 33,722,473 - 33,730,354 (-) NCBI MGSCv36 mm8 Celera 17 36,864,043 - 36,873,770 (-) NCBI Celera Cytogenetic Map 17 B1 NCBI cM Map 17 17.98 NCBI
Brd2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955437 1,584,479 - 1,592,826 (+) Ensembl ChiLan1.0 ChiLan1.0 NW_004955437 1,584,890 - 1,592,486 (+) NCBI ChiLan1.0 ChiLan1.0
BRD2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 5 47,443,604 - 47,456,467 (+) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 6 43,315,229 - 43,328,092 (+) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 6 32,538,130 - 32,550,823 (+) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 6 33,657,488 - 33,666,054 (+) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 6 33,657,648 - 33,666,031 (+) Ensembl panpan1.1 panPan2
BRD2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 12 2,534,034 - 2,546,029 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 12 2,534,034 - 2,546,029 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 12 2,615,604 - 2,627,599 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 12 2,864,982 - 2,876,982 (+) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 12 2,864,927 - 2,876,950 (+) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 12 2,533,065 - 2,545,060 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 12 2,614,613 - 2,626,605 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 12 2,689,162 - 2,701,159 (+) NCBI UU_Cfam_GSD_1.0
Brd2 Squirrel Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl HiC_Itri_2 NW_024404946 38,145,455 - 38,153,085 (+) NCBI HiC_Itri_2 SpeTri2.0 Ensembl NW_004936476 25,807,163 - 25,818,899 (-) Ensembl SpeTri2.0 SpeTri2.0 Ensembl SpeTri2.0 NW_004936476 25,807,179 - 25,818,914 (-) NCBI SpeTri2.0 SpeTri2.0 SpeTri2.0
BRD2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 7 25,150,564 - 25,162,584 (+) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 7 25,096,579 - 25,162,591 (+) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 7 29,463,191 - 29,529,204 (+) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
BRD2
Brd2
.
Predicted Target Of
Count of predictions: 129 Count of miRNA genes: 92 Interacting mature miRNAs: 98 Transcripts: ENSRNOT00000000535, ENSRNOT00000060194 Prediction methods: Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction
2306850 Pia40 Pristane induced arthritis QTL 40 0.0001 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 20 1527959 5304575 Rat 1354642 Despr15 Despair related QTL 15 0.0027 locomotor behavior trait (VT:0001392) amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958) 20 1 24159021 Rat 4889857 Pur27 Proteinuria QTL 27 12.2 0.001 urine total protein amount (VT:0000032) urine total protein excretion rate (CMO:0000756) 20 4606607 17617956 Rat 9590109 Sffal8 Serum free fatty acids level QTL 8 5.32 0.01 blood free fatty acid amount (VT:0001553) plasma free fatty acids level (CMO:0000546) 20 1 29191651 Rat 9590275 Scort15 Serum corticosterone level QTL 15 3.48 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 20 1 29191651 Rat 7175096 Tcs1 T cell selection QTL 1 T cell selection trait (VT:0004917) expression 20 4727078 5024580 Rat 6893685 Bw111 Body weight QTL 111 2.7 0.004 body mass (VT:0001259) body weight (CMO:0000012) 20 1 32578807 Rat 1641915 Colcr9 Colorectal carcinoma resistance QTL 9 2.97 0.0024 intestine integrity trait (VT:0010554) benign colorectal tumor number (CMO:0001795) 20 1530655 46530655 Rat 2317057 Aia27 Adjuvant induced arthritis QTL 27 2.83 joint integrity trait (VT:0010548) right rear ankle joint diameter (CMO:0002150) 20 2892597 26381954 Rat 61474 Eae1 Experimental allergic encephalomyelitis QTL 1 3 nervous system integrity trait (VT:0010566) experimental autoimmune encephalomyelitis severity score (CMO:0001419) 20 4606607 6691706 Rat 7387283 Uae44 Urinary albumin excretion QTL 44 0.1712 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 20 1 26123605 Rat 7411668 Foco32 Food consumption QTL 32 8 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 20 1 36600972 Rat 2305926 Iddm37 Insulin dependent diabetes mellitus QTL 37 6 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 20 1527842 46527842 Rat 1600382 Edcs3 Endometrial carcinoma susceptibility QTL3 3.5 0.003 uterus morphology trait (VT:0001120) percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759) 20 1 25159026 Rat 1558640 Prcs2 Prostate cancer susceptibility QTL 2 3.3 prostate integrity trait (VT:0010571) percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943) 20 4606607 17617956 Rat 1331772 Cdexp2 CD45RC expression in CD8 T cells QTL 2 5.7 CD8-positive T cell quantity (VT:0008077) blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990) 20 3621649 10078919 Rat 8694189 Bw153 Body weight QTL 153 3.13 0.001 body mass (VT:0001259) body weight gain (CMO:0000420) 20 1 29191651 Rat 1300152 Bp195 Blood pressure QTL 195 3.46 arterial blood pressure trait (VT:2000000) systolic blood pressure (CMO:0000004) 20 3621649 9243559 Rat 9589155 Insul32 Insulin level QTL 32 6.38 0.001 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 20 1 29191651 Rat 7411650 Foco23 Food consumption QTL 23 20.7 0.001 eating behavior trait (VT:0001431) feed conversion ratio (CMO:0001312) 20 1 29191651 Rat 2317851 Alcrsp22 Alcohol response QTL 22 3.2 0.05 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 20 1 27339237 Rat 1598816 Memor12 Memory QTL 12 2.4 exploratory behavior trait (VT:0010471) average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674) 20 2606836 47606836 Rat 61432 Cia1 Collagen induced arthritis QTL 1 joint integrity trait (VT:0010548) joint inflammation composite score (CMO:0000919) 20 3621656 14101050 Rat 1641893 Alcrsp7 Alcohol response QTL 7 response to alcohol trait (VT:0010489) duration of loss of righting reflex (CMO:0002289) 20 1 27339237 Rat 9590252 Scort12 Serum corticosterone level QTL 12 20.46 0.001 blood corticosterone amount (VT:0005345) plasma corticosterone level (CMO:0001173) 20 1 36600972 Rat
AW228947
Rat Assembly Chr Position (strand) Source JBrowse Rnor_5.0 20 5,990,258 - 5,990,366 NCBI Rnor5.0 Rnor_5.0 20 7,330,134 - 7,330,242 NCBI Rnor5.0 Rnor_5.0 10 61,374,939 - 61,375,047 NCBI Rnor5.0 RGSC_v3.4 10 62,114,541 - 62,114,648 UniSTS RGSC3.4 RGSC_v3.4 20 4,871,557 - 4,871,664 UniSTS RGSC3.4 Celera 20 6,335,782 - 6,335,889 UniSTS Cytogenetic Map 10 q24 UniSTS Cytogenetic Map 20 p12 UniSTS
CGCb741
Rat Assembly Chr Position (strand) Source JBrowse GRCr8 20 4,733,603 - 4,733,777 (+) Marker Load Pipeline mRatBN7.2 20 4,731,699 - 4,731,873 (-) MAPPER mRatBN7.2 mRatBN7.2 20 4,731,699 - 4,731,873 (+) MAPPER mRatBN7.2 Rnor_6.0 20 5,265,648 - 5,265,821 NCBI Rnor6.0 Rnor_6.0 20 3,914,071 - 3,914,244 NCBI Rnor6.0 Rnor_5.0 20 7,326,709 - 7,326,882 UniSTS Rnor5.0 Rnor_5.0 20 5,993,619 - 5,993,792 UniSTS Rnor5.0 RGSC_v3.4 20 4,868,131 - 4,868,304 UniSTS RGSC3.4 Celera 20 6,332,356 - 6,332,529 UniSTS Cytogenetic Map 20 p12 UniSTS
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
9
11
49
113
91
90
59
25
59
6
218
97
93
45
60
31
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSRNOT00000000535 ⟹ ENSRNOP00000000535
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 20 4,728,151 - 4,735,382 (+) Ensembl Rnor_6.0 Ensembl 20 5,262,120 - 5,269,328 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000060194
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 20 4,730,185 - 4,735,382 (+) Ensembl Rnor_6.0 Ensembl 20 3,910,583 - 3,917,224 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000077454
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl 20 3,910,555 - 3,917,426 (-) Ensembl
Ensembl Acc Id:
ENSRNOT00000080585 ⟹ ENSRNOP00000072049
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source mRatBN7.2 Ensembl 20 4,728,518 - 4,735,388 (+) Ensembl Rnor_6.0 Ensembl 20 5,262,466 - 5,269,337 (+) Ensembl
Ensembl Acc Id:
ENSRNOT00000082900 ⟹ ENSRNOP00000070430
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source Rnor_6.0 Ensembl 20 5,262,946 - 5,265,935 (+) Ensembl
RefSeq Acc Id:
NM_212495 ⟹ NP_997660
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 4,730,079 - 4,737,286 (+) NCBI mRatBN7.2 20 4,728,175 - 4,735,382 (+) NCBI Rnor_6.0 20 3,910,562 - 3,917,769 (-) NCBI Rnor_5.0 20 7,323,184 - 7,330,398 (+) NCBI RGSC_v3.4 20 4,864,606 - 4,871,813 (+) RGD Celera 20 6,328,831 - 6,336,038 (+) RGD
Sequence:
GCAGCCTCTAGGACGAGCTGGAGGATTGTGCCTACTGACCCAGAGTCTTGGAGCCTCCGCGGGCCGCCAGTACAATCCACGTCCATCCGCTCGGAAATGGCCTTCGTCCCGGCCCGTGACCGCTCCCG
hide sequence
RefSeq Acc Id:
XM_008772772 ⟹ XP_008770994
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 4,730,880 - 4,737,286 (+) NCBI mRatBN7.2 20 4,729,003 - 4,735,389 (+) NCBI Rnor_6.0 20 3,910,555 - 3,916,979 (-) NCBI
Sequence:
GCAGCTGTTGACGCGAGCTCGCGGAGGGGGCTGCGACGGTTTTGAAGCGGTGGCGGCGGCCCAG
hide sequence
RefSeq Acc Id:
XM_017601578 ⟹ XP_017457067
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 4,728,284 - 4,737,286 (+) NCBI mRatBN7.2 20 4,727,078 - 4,735,374 (+) NCBI Rnor_6.0 20 3,910,555 - 3,918,918 (-) NCBI
Sequence:
GAGGGCTGCAGAGCAGCGCCGCCGCCTCCTCGGCTCGCCCTCCTCCCTGGCGCTGACCGATGGAAGAGGCGCTCCGTGGGGAGGACTCCCGGCCCGATGGGGGCGGGGGGCTTCAGTTCGCCCACGCT
hide sequence
RefSeq Acc Id:
XM_039098498 ⟹ XP_038954426
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 4,728,945 - 4,734,852 (+) NCBI mRatBN7.2 20 4,728,743 - 4,732,948 (+) NCBI
RefSeq Acc Id:
XM_063279018 ⟹ XP_063135088
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 4,728,282 - 4,737,286 (+) NCBI
RefSeq Acc Id:
XM_063279019 ⟹ XP_063135089
Type:
CODING
Position:
Rat Assembly Chr Position (strand) Source GRCr8 20 4,732,386 - 4,737,286 (+) NCBI
RefSeq Acc Id:
NP_997660 ⟸ NM_212495
- UniProtKB:
Q6MGA9 (UniProtKB/Swiss-Prot), A6JJF0 (UniProtKB/TrEMBL), A0A8I5ZYL9 (UniProtKB/TrEMBL)
- Sequence:
MLQNVTPHKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLAPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRR
hide sequence
RefSeq Acc Id:
XP_017457067 ⟸ XM_017601578
- Peptide Label:
isoform X1
- UniProtKB:
Q6MGA9 (UniProtKB/Swiss-Prot), A6JJF0 (UniProtKB/TrEMBL), A0A8I5ZYL9 (UniProtKB/TrEMBL)
- Sequence:
MLQNVTPHKLPGEGNAGLLGLGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLAPANPPPPE
hide sequence
RefSeq Acc Id:
XP_008770994 ⟸ XM_008772772
- Peptide Label:
isoform X2
- UniProtKB:
A0A8I5ZYL9 (UniProtKB/TrEMBL)
- Sequence:
MASVPALQLAPANPPPPEVSNPKKPGRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQ
hide sequence
Ensembl Acc Id:
ENSRNOP00000070430 ⟸ ENSRNOT00000082900
Ensembl Acc Id:
ENSRNOP00000072049 ⟸ ENSRNOT00000080585
Ensembl Acc Id:
ENSRNOP00000000535 ⟸ ENSRNOT00000000535
RefSeq Acc Id:
XP_038954426 ⟸ XM_039098498
- Peptide Label:
isoform X4
RefSeq Acc Id:
XP_063135088 ⟸ XM_063279018
- Peptide Label:
isoform X1
- UniProtKB:
Q6MGA9 (UniProtKB/Swiss-Prot), A6JJF0 (UniProtKB/TrEMBL), A0A8I5ZYL9 (UniProtKB/TrEMBL)
RefSeq Acc Id:
XP_063135089 ⟸ XM_063279019
- Peptide Label:
isoform X3
- UniProtKB:
A0A0G2K1Z8 (UniProtKB/TrEMBL), A0A8I5ZYL9 (UniProtKB/TrEMBL)
Date
Current Symbol
Current Name
Previous Symbol
Previous Name
Description
Reference
Status
2021-03-09
Brd2
bromodomain containing 2
LOC108348112
bromodomain-containing protein 2
Data merged from RGD:11509343
737654 PROVISIONAL
2016-08-02
LOC108348112
bromodomain-containing protein 2
Symbol and Name status set to provisional
70820 PROVISIONAL
2006-03-30
Brd2
bromodomain containing 2
bromodomain-containing 2
Name updated
1299863 APPROVED
2005-02-14
Brd2
bromodomain-containing 2
Symbol and Name status set to provisional
70820 PROVISIONAL
