BRD2 (bromodomain containing 2) - Rat Genome Database

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Gene: BRD2 (bromodomain containing 2) Homo sapiens
Analyze
Symbol: BRD2
Name: bromodomain containing 2
RGD ID: 1350574
HGNC Page HGNC:1103
Description: Enables several functions, including chromatin binding activity; histone reader activity; and lysine-acetylated histone binding activity. Involved in several processes, including chromatin looping; nucleosome assembly; and positive regulation of T-helper 17 cell lineage commitment. Located in nuclear speck. Is active in chromatin. Implicated in B-cell lymphoma; B-lymphoblastic leukemia/lymphoma; juvenile myoclonic epilepsy; and photosensitivity disease. Biomarker of melanoma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: BRD2 intronic transcript 1; BRD2-IT1; bromodomain-containing 2; bromodomain-containing protein 2; D6S113E; DKFZp686N0336; female sterile homeotic-related gene 1; FLJ31942; FSH; FSHRG1; FSRG1; KIAA9001; NAT; O27.1.1; really interesting new gene 3 protein; RING3; RNF3
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,968,594 - 32,981,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,968,594 - 32,981,505 (+)EnsemblGRCh38hg38GRCh38
GRCh37632,936,371 - 32,949,282 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,044,415 - 33,057,059 (+)NCBINCBI36Build 36hg18NCBI36
Build 34633,044,414 - 33,057,059NCBI
Celera634,485,349 - 34,498,195 (+)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,678,978 - 32,691,818 (+)NCBIHuRef
CHM1_1632,937,242 - 32,950,091 (+)NCBICHM1_1
T2T-CHM13v2.0632,789,953 - 32,802,871 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
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Original Reference(s)
BRD2HumanB-cell lymphoma  IMP 9586345 RGD 
BRD2HumanB-lymphoblastic leukemia/lymphoma  IMP 9586345 RGD 
BRD2Humanhyperinsulinism  ISOBrd2 (Mus musculus)9586446 RGD 
BRD2Humanjuvenile myoclonic epilepsy  IAGP 1358444DNA:SNPs:promoter (human)RGD 
BRD2Humanmelanoma  IEP 9586346protein:mRNA:skin:RGD 
BRD2Humanobesity  ISOBrd2 (Mus musculus)9586446 RGD 
BRD2Humanphotosensitivity disease susceptibilityIAGP 9586343DNA:SNPs and haplotype: :RGD 
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Original Reference(s)
BRD2Humanproteasome-associated autoinflammatory syndrome 1  IAGP (Homo sapiens)8554872ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1ClinVarPMID:28492532
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Original Reference(s)
BRD2Humanglioblastoma  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:27388964
BRD2Humanmedulloblastoma  EXP 11554173CTD Direct Evidence: marker/mechanismCTDPMID:24231268

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Original Reference(s)
BRD2Human(+)-schisandrin B multiple interactionsISOBrd2 (Rattus norvegicus)6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of BRD2 mRNA]CTDPMID:31150632
BRD2Human(1->4)-beta-D-glucan multiple interactionsISOBrd2 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of BRD2 mRNACTDPMID:36331819
BRD2Human(S)-nicotine increases expressionISOBrd2 (Mus musculus)6480464Nicotine results in increased expression of BRD2 mRNACTDPMID:33640489
BRD2Human17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of BRD2 mRNACTDPMID:11179685
BRD2Human17beta-estradiol increases expressionISOBrd2 (Mus musculus)6480464Estradiol results in increased expression of BRD2 mRNACTDPMID:39298647
BRD2Human17beta-estradiol multiple interactionsEXP 64804643 more ...CTDPMID:11179685
BRD2Human2,3,7,8-tetrachlorodibenzodioxine multiple interactionsEXP 6480464Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of BRD2 mRNA]CTDPMID:11179685
BRD2Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISOBrd2 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin affects the expression of BRD2 mRNACTDPMID:33387578
BRD2Human2,3,7,8-tetrachlorodibenzodioxine increases expressionISOBrd2 (Rattus norvegicus)6480464Tetrachlorodibenzodioxin results in increased expression of BRD2 mRNACTDPMID:34747641
BRD2Human2,3,7,8-tetrachlorodibenzodioxine affects expressionISOBrd2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of BRD2 mRNACTDPMID:20702594 and PMID:21570461
BRD2Human2,3,7,8-Tetrachlorodibenzofuran affects expressionISOBrd2 (Mus musculus)64804642 more ...CTDPMID:20702594
BRD2Human2,4-dinitrotoluene affects expressionISOBrd2 (Rattus norvegicus)64804642 and 4-dinitrotoluene affects the expression of BRD2 mRNACTDPMID:21346803
BRD2Human2-hydroxypropanoic acid increases expressionEXP 6480464Lactic Acid results in increased expression of BRD2 mRNACTDPMID:30851411
BRD2Human3,3'-diindolylmethane multiple interactionsEXP 64804643 and 3'-diindolylmethane inhibits the reaction [Estradiol results in increased expression of BRD2 mRNA]CTDPMID:11179685
BRD2Human4,4'-sulfonyldiphenol increases expressionISOBrd2 (Mus musculus)6480464bisphenol S results in increased expression of BRD2 mRNACTDPMID:39298647
BRD2Human6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactionsEXP 6480464BRD2 mutant form inhibits the reaction [6-chloro-2 more ...CTDPMID:26212199
BRD2Human6-propyl-2-thiouracil decreases expressionISOBrd2 (Rattus norvegicus)6480464Propylthiouracil results in decreased expression of BRD2 mRNACTDPMID:22504374 and PMID:30047161
BRD2Humanacrolein multiple interactionsEXP 6480464[Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of and results in increased oxidation of BRD2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of and results in increased oxidation of BRD2 mRNACTDPMID:32699268
BRD2Humanacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of BRD2 mRNACTDPMID:32763439
BRD2Humanafimoxifene decreases response to substanceEXP 6480464BRD2 results in decreased susceptibility to afimoxifeneCTDPMID:21233418

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Biological Process
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Original Reference(s)
BRD2Humanchromatin looping involved_inIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
BRD2Humanchromatin looping involved_inIDA 150520179 PMID:35410381UniProtPMID:35410381
BRD2Humanchromatin organization involved_inIEAUniProtKB-KW:KW-0156150520179 UniProtGO_REF:0000043
BRD2Humanchromatin remodeling involved_inIBAPANTHER:PTN002914388 more ...150520179 GO_CentralGO_REF:0000033
BRD2Humanneural tube closure acts_upstream_of_or_withinIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
BRD2Humannucleosome assembly involved_inIMP 150520179 PMID:18406326UniProtPMID:18406326
BRD2Humanpositive regulation of T-helper 17 cell lineage commitment involved_inIDA 150520179 PMID:28262505UniProtPMID:28262505
BRD2Humanpositive regulation of T-helper 17 cell lineage commitment involved_inIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
BRD2Humanprotein localization to chromatin involved_inIDA 150520179 PMID:28262505UniProtPMID:28262505
BRD2Humanprotein localization to chromatin involved_inIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
BRD2Humanregulation of gene expression involved_inIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
BRD2Humanregulation of transcription by RNA polymerase II involved_inIDA 150520179 PMID:18406326 and PMID:28262505UniProtPMID:18406326 and PMID:28262505
BRD2Humanregulation of transcription by RNA polymerase II involved_inIBAFB:FBgn0004656 more ...150520179 GO_CentralGO_REF:0000033
BRD2Humanregulation of transcription by RNA polymerase II involved_inIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
BRD2Humanspermatogenesis involved_inTAS 150520179 PMID:9693039PINCPMID:9693039
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Cellular Component
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Original Reference(s)
BRD2Humanchromatin is_active_inIBAPANTHER:PTN002914388 more ...150520179 GO_CentralGO_REF:0000033
BRD2Humanchromatin is_active_inIDA 150520179 PMID:17848202 more ...UniProtPMID:17848202 more ...
BRD2Humanchromosome located_inIEAUniProtKB-KW:KW-0158150520179 UniProtGO_REF:0000043
BRD2Humanchromosome located_inIEAUniProtKB-SubCell:SL-0468150520179 UniProtGO_REF:0000044
BRD2Humancytoplasm located_inIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
BRD2Humannuclear speck located_inIDA 150520179 HPAGO_REF:0000052
BRD2Humannucleoplasm located_inTAS 150520179 ReactomeReactome:R-HSA-8951977 more ...
BRD2Humannucleoplasm located_inIDA 150520179 HPAGO_REF:0000052
BRD2Humannucleus located_inIDA 150520179 PMID:25593309 and PMID:8595877UniProtPMID:25593309 and PMID:8595877
BRD2Humannucleus is_active_inIBAFB:FBgn0004656 more ...150520179 GO_CentralGO_REF:0000033
BRD2Humannucleus located_inIEAARBA:ARBA00026330150520179 UniProtGO_REF:0000117
BRD2Humannucleus located_inIEAUniProtKB-SubCell:SL-0191150520179 UniProtGO_REF:0000044
BRD2Humannucleus located_inIEAUniProtKB-KW:KW-0539150520179 UniProtGO_REF:0000043
BRD2Humannucleus located_inIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
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Molecular Function
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Original Reference(s)
BRD2Humanacetylation-dependent protein binding enablesIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
BRD2Humanacetylation-dependent protein binding enablesIDA 150520179 PMID:28262505UniProtPMID:28262505
BRD2Humanchromatin binding enablesIBAFB:FBgn0004656 more ...150520179 GO_CentralGO_REF:0000033
BRD2Humanhistone binding enablesIBAFB:FBgn0004656 more ...150520179 GO_CentralGO_REF:0000033
BRD2Humanhistone H3K14ac reader activity enablesIDA 150520179 PMID:18406326GO_CentralPMID:18406326
BRD2Humanhistone H4K12ac reader activity enablesIEAUniProtKB:Q7JJ13 and ensembl:ENSMUSP00000025193150520179 EnsemblGO_REF:0000107
BRD2Humanhistone H4K12ac reader activity enablesIDA 150520179 PMID:17848202 more ...UniProtPMID:17848202 more ...
BRD2Humanhistone H4K5ac reader activity enablesIDA 150520179 PMID:18406326 and PMID:20709061UniProtPMID:18406326 and PMID:20709061
BRD2Humanlysine-acetylated histone binding enablesISOBrd2 (Mus musculus)9068941 PMID:14731392UniProtPMID:14731392
BRD2Humanprotein binding enablesIPIUniProtKB:Q13761150520179 PMID:24229708IntActPMID:24229708
BRD2Humanprotein binding enablesIPIUniProtKB:P62805150520179 PMID:20709061IntActPMID:20709061
BRD2Humanprotein serine/threonine kinase activity enablesIDA 150520179 PMID:8595877FlyBasePMID:8595877
BRD2Humanprotein serine/threonine kinase activity enablesIBAFB:FBgn0004656 more ...150520179 GO_CentralGO_REF:0000033
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RGD Manual Annotations


  
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Original Reference(s)
BRD2Humanhistone modification pathway   TAS 9479075 RGD 

#
Reference Title
Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. E mu-BRD2 transgenic mice develop B-cell lymphoma and leukemia. Greenwald RJ, etal., Blood. 2004 Feb 15;103(4):1475-84. Epub 2003 Oct 16.
3. Association of BRD2 polymorphisms with photoparoxysmal response. Lorenz S, etal., Neurosci Lett. 2006 May 29;400(1-2):135-9. Epub 2006 Mar 3.
4. BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy. Pal DK, etal., Am J Hum Genet 2003 Aug;73(2):261-70. Epub 2003 Jun 25.
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. The bromodomain: From epigenome reader to druggable target. Sanchez R, etal., Biochim Biophys Acta. 2014 Aug;1839(8):676-685. doi: 10.1016/j.bbagrm.2014.03.011. Epub 2014 Mar 28.
7. BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy. Segura MF, etal., Cancer Res. 2013 Oct 15;73(20):6264-76. doi: 10.1158/0008-5472.CAN-13-0122-T. Epub 2013 Aug 15.
8. Brd2 disruption in mice causes severe obesity without Type 2 diabetes. Wang F, etal., Biochem J. 2009 Dec 14;425(1):71-83. doi: 10.1042/BJ20090928.
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PMID:1350857   PMID:1352711   PMID:1663500   PMID:8595877   PMID:8781126   PMID:9373153   PMID:9693039   PMID:10934046   PMID:10965846   PMID:11502199   PMID:11983150   PMID:12145330  
PMID:12366783   PMID:12477932   PMID:12600283   PMID:14574404   PMID:14702039   PMID:14731392   PMID:15146197   PMID:15302935   PMID:15342556   PMID:15489334   PMID:15548137   PMID:15949438  
PMID:16344560   PMID:16512664   PMID:16786191   PMID:16940503   PMID:17081983   PMID:17111193   PMID:17148447   PMID:17166848   PMID:17848202   PMID:17999746   PMID:18406326   PMID:19204726  
PMID:19322201   PMID:19454010   PMID:19766566   PMID:19851445   PMID:19953286   PMID:20036832   PMID:20048151   PMID:20467437   PMID:20587610   PMID:20709061   PMID:20811636   PMID:21555454  
PMID:21608014   PMID:21873635   PMID:22035730   PMID:22766109   PMID:23115324   PMID:23255218   PMID:23455922   PMID:23756480   PMID:23858473   PMID:24048450   PMID:24049186   PMID:24146614  
PMID:24229708   PMID:24711643   PMID:24733848   PMID:24981860   PMID:25049379   PMID:25281560   PMID:25544563   PMID:25593309   PMID:26186194   PMID:26324948   PMID:26344197   PMID:26496610  
PMID:26586120   PMID:27248496   PMID:27634302   PMID:27705803   PMID:27864998   PMID:27880917   PMID:28242625   PMID:28262505   PMID:28319085   PMID:28514442   PMID:28524877   PMID:28561026  
PMID:28588073   PMID:28591577   PMID:28805820   PMID:28805822   PMID:28945351   PMID:28977666   PMID:29018219   PMID:29044188   PMID:29437854   PMID:29568061   PMID:29608786   PMID:29956673  
PMID:29996942   PMID:30300821   PMID:30415952   PMID:30472188   PMID:30554943   PMID:30719712   PMID:30804502   PMID:30884312   PMID:30938974   PMID:31076518   PMID:31239290   PMID:31311807  
PMID:31444232   PMID:31504794   PMID:31527615   PMID:31586073   PMID:31753913   PMID:31776466   PMID:31792058   PMID:32051553   PMID:32151278   PMID:32353859   PMID:32416067   PMID:32459053  
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BRD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38632,968,594 - 32,981,505 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl632,968,594 - 32,981,505 (+)EnsemblGRCh38hg38GRCh38
GRCh37632,936,371 - 32,949,282 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,044,415 - 33,057,059 (+)NCBINCBI36Build 36hg18NCBI36
Build 34633,044,414 - 33,057,059NCBI
Celera634,485,349 - 34,498,195 (+)NCBICelera
Cytogenetic Map6p21.32NCBI
HuRef632,678,978 - 32,691,818 (+)NCBIHuRef
CHM1_1632,937,242 - 32,950,091 (+)NCBICHM1_1
T2T-CHM13v2.0632,789,953 - 32,802,871 (+)NCBIT2T-CHM13v2.0
Brd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391734,330,993 - 34,341,581 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1734,330,997 - 34,341,608 (-)EnsemblGRCm39 Ensembl
GRCm381734,112,019 - 34,122,814 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1734,112,023 - 34,122,634 (-)EnsemblGRCm38mm10GRCm38
MGSCv371734,248,964 - 34,258,692 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361733,722,473 - 33,730,354 (-)NCBIMGSCv36mm8
Celera1736,864,043 - 36,873,770 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.98NCBI
Brd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8204,728,282 - 4,737,286 (+)NCBIGRCr8
mRatBN7.2204,727,078 - 4,735,389 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl204,728,151 - 4,735,388 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx205,480,415 - 5,487,612 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0204,842,158 - 4,849,355 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0205,323,436 - 5,330,635 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0203,910,555 - 3,921,074 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,262,120 - 5,269,337 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl203,910,555 - 3,917,426 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,323,184 - 7,330,398 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4204,864,606 - 4,871,813 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1204,864,832 - 4,872,040 (+)NCBI
Celera206,328,831 - 6,336,038 (+)NCBICelera
Cytogenetic Map20p12NCBI
Brd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554371,584,479 - 1,592,826 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554371,584,890 - 1,592,486 (+)NCBIChiLan1.0ChiLan1.0
BRD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2547,443,604 - 47,456,467 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1643,315,229 - 43,328,092 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0632,538,130 - 32,550,823 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1633,657,488 - 33,666,054 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl633,657,648 - 33,666,031 (+)Ensemblpanpan1.1panPan2
BRD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1122,534,034 - 2,546,029 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl122,534,034 - 2,546,029 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha122,615,604 - 2,627,599 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0122,864,982 - 2,876,982 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl122,864,927 - 2,876,950 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1122,533,065 - 2,545,060 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0122,614,613 - 2,626,605 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0122,689,162 - 2,701,159 (+)NCBIUU_Cfam_GSD_1.0
Brd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494638,145,455 - 38,153,085 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647625,807,163 - 25,818,899 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647625,807,179 - 25,818,914 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BRD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl725,150,564 - 25,162,584 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1725,096,579 - 25,162,591 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2729,463,191 - 29,529,204 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BRD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11739,113,519 - 39,126,267 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604432,757,658 - 32,770,463 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Brd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475423,742,509 - 23,750,062 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475423,742,506 - 23,750,668 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in BRD2
95 total Variants

1 to 10 of 104 rows
Name
Type
Condition(s)
Position(s)
Clinical significance
NM_005104.4(BRD2):c.1330-4G>C single nucleotide variant BRD2-related disorder [RCV003982879]|not specified [RCV000594555] Chr6:32977753 [GRCh38]
Chr6:32945530 [GRCh37]
Chr6:6p21.32
benign
NM_005104.4(BRD2):c.1497GGA[1] (p.Glu500del) microsatellite BRD2-related disorder [RCV003974974]|not provided [RCV000594240] Chr6:32977922..32977924 [GRCh38]
Chr6:32945699..32945701 [GRCh37]
Chr6:6p21.32
benign|uncertain significance
NM_005104.4(BRD2):c.1579-8del deletion not specified [RCV000593467] Chr6:32978111 [GRCh38]
Chr6:32945895 [GRCh37]
Chr6:6p21.32
benign
NM_005104.4(BRD2):c.35C>T (p.Pro12Leu) single nucleotide variant not specified [RCV000202731] Chr6:32974467 [GRCh38]
Chr6:32942244 [GRCh37]
Chr6:6p21.32
uncertain significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
NM_005104.4(BRD2):c.883G>T (p.Ala295Ser) single nucleotide variant not specified [RCV004298428] Chr6:32976619 [GRCh38]
Chr6:32944396 [GRCh37]
Chr6:6p21.32
uncertain significance
NM_005104.4(BRD2):c.25A>G (p.Asn9Asp) single nucleotide variant not specified [RCV004323012] Chr6:32972923 [GRCh38]
Chr6:32940700 [GRCh37]
Chr6:6p21.32
uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
1 to 10 of 104 rows

Predicted Target Of
Summary Value
Count of predictions:7785
Count of miRNA genes:1129
Interacting mature miRNAs:1442
Transcripts:ENST00000374825, ENST00000374831, ENST00000395287, ENST00000395289, ENST00000443797, ENST00000449025, ENST00000449085, ENST00000456339, ENST00000463639, ENST00000464592, ENST00000469132, ENST00000481259, ENST00000482838, ENST00000482914, ENST00000495733, ENST00000496118, ENST00000580234, ENST00000581002, ENST00000584808, ENST00000606059, ENST00000607833
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 26 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
597432349GWAS1528423_Hprotein measurement QTL GWAS1528423 (human)8e-17protein measurement63297597532975976Human
597452377GWAS1548451_Hstreptococcus seropositivity QTL GWAS1548451 (human)2e-09streptococcus seropositivity63297854532978546Human
597045726GWAS1141800_Hhemoglobin measurement QTL GWAS1141800 (human)2e-08hemoglobin measurementhemoglobin measurement (CMO:0000508)63297775332977754Human
597061854GWAS1157928_Htonsillectomy risk measurement QTL GWAS1157928 (human)0.0000004tonsillectomy risk measurement63297792132977922Human
597454930GWAS1551004_Hstreptococcus seropositivity QTL GWAS1551004 (human)2e-18streptococcus seropositivity63297854532978546Human
597431187GWAS1527261_Hprotein measurement QTL GWAS1527261 (human)2e-17protein measurement63297882932978830Human
597156101GWAS1252175_Hsarcoidosis QTL GWAS1252175 (human)3e-08sarcoidosis63296866432968665Human
597511432GWAS1607506_Htriglyceride measurement QTL GWAS1607506 (human)1e-36triglyceride measurementblood triglyceride level (CMO:0000118)63297973932979740Human
597162625GWAS1258699_Hdihomo-linoleate 20:2n6 measurement QTL GWAS1258699 (human)0.000005dihomo-linoleate 20:2n6 measurement63297817932978180Human
597389068GWAS1485142_Hsusceptibility to Mycobacterium tuberculosis infection measurement QTL GWAS1485142 (human)8e-09susceptibility to Mycobacterium tuberculosis infection measurement63297854532978546Human

1 to 10 of 26 rows
G67884  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,943,866 - 32,944,082UniSTSGRCh37
Build 36633,051,844 - 33,052,060RGDNCBI36
Celera634,492,777 - 34,492,993RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,686,400 - 32,686,616UniSTS
D6S2656  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,942,958 - 32,943,257UniSTSGRCh37
Build 36633,050,936 - 33,051,235RGDNCBI36
Celera634,491,869 - 34,492,168RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,685,490 - 32,685,791UniSTS
RING3-CA  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,942,887 - 32,943,119UniSTSGRCh37
Build 36633,050,865 - 33,051,097RGDNCBI36
Celera634,491,798 - 34,492,030RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,685,419 - 32,685,653UniSTS
A008D22  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,949,128 - 32,949,242UniSTSGRCh37
Build 36633,057,106 - 33,057,220RGDNCBI36
Celera634,498,041 - 34,498,155RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,691,664 - 32,691,778UniSTS
GeneMap99-GB4 RH Map6120.09UniSTS
NCBI RH Map6509.1UniSTS
RH18121  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,948,650 - 32,948,847UniSTSGRCh37
Build 36633,056,628 - 33,056,825RGDNCBI36
Celera634,497,563 - 34,497,760RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,691,186 - 32,691,383UniSTS
GeneMap99-GB4 RH Map6119.82UniSTS
NIB1722  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,948,957 - 32,949,057UniSTSGRCh37
Build 36633,056,935 - 33,057,035RGDNCBI36
Celera634,497,870 - 34,497,970RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,691,493 - 32,691,593UniSTS
GeneMap99-GB4 RH Map6119.43UniSTS
Whitehead-RH Map6179.7UniSTS
NCBI RH Map6509.1UniSTS
STS-T87864  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,943,826 - 32,944,139UniSTSGRCh37
Build 36633,051,804 - 33,052,117RGDNCBI36
Celera634,492,737 - 34,493,050RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,686,360 - 32,686,673UniSTS
GeneMap99-GB4 RH Map1941.45UniSTS
NCBI RH Map1910.0UniSTS
SGC31960  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,945,705 - 32,945,950UniSTSGRCh37
Build 36633,053,683 - 33,053,928RGDNCBI36
Celera634,494,616 - 34,494,861RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,688,239 - 32,688,484UniSTS
GeneMap99-GB4 RH Map6119.82UniSTS
GeneMap99-GB4 RH Map6145.45UniSTS
Whitehead-RH Map6179.7UniSTS
NCBI RH Map6509.1UniSTS
D6S1894  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,948,615 - 32,948,727UniSTSGRCh37
Build 36633,056,593 - 33,056,705RGDNCBI36
Celera634,497,528 - 34,497,640RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,691,151 - 32,691,263UniSTS
M2_2_23  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,942,960 - 32,943,256UniSTSGRCh37
Build 36633,050,938 - 33,051,234RGDNCBI36
Celera634,491,871 - 34,492,167RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,685,492 - 32,685,790UniSTS
CGCb250  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,944,039 - 32,944,179UniSTSGRCh37
Build 36633,052,017 - 33,052,157RGDNCBI36
Celera634,492,950 - 34,493,090RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,686,573 - 32,686,713UniSTS
CGCb278  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,939,721 - 32,939,834UniSTSGRCh37
Build 36633,047,699 - 33,047,812RGDNCBI36
Celera634,488,632 - 34,488,745RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,682,253 - 32,682,366UniSTS
CGCb369  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,945,912 - 32,946,017UniSTSGRCh37
Build 36633,053,890 - 33,053,995RGDNCBI36
Celera634,494,823 - 34,494,928RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,688,446 - 32,688,551UniSTS
CGCb535  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,942,226 - 32,942,396UniSTSGRCh37
Build 36633,050,204 - 33,050,374RGDNCBI36
Celera634,491,137 - 34,491,307RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,684,758 - 32,684,928UniSTS
CGCb688  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,943,096 - 32,943,257UniSTSGRCh37
Build 36633,051,074 - 33,051,235RGDNCBI36
Celera634,492,007 - 34,492,168RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,685,630 - 32,685,791UniSTS
CGCb741  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,943,901 - 32,944,056UniSTSGRCh37
Build 36633,051,879 - 33,052,034RGDNCBI36
Celera634,492,812 - 34,492,967RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,686,435 - 32,686,590UniSTS
CGCb781  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,946,063 - 32,946,199UniSTSGRCh37
Build 36633,054,041 - 33,054,177RGDNCBI36
Celera634,494,974 - 34,495,110RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,688,597 - 32,688,733UniSTS
CGCb787  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,936,138 - 32,936,283UniSTSGRCh37
Build 36633,044,116 - 33,044,261RGDNCBI36
Celera634,485,050 - 34,485,195RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,678,679 - 32,678,824UniSTS
CGCb908  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,944,686 - 32,944,810UniSTSGRCh37
Build 36633,052,664 - 33,052,788RGDNCBI36
Celera634,493,597 - 34,493,721RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,687,220 - 32,687,344UniSTS
CGCbi2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,941,825 - 32,942,269UniSTSGRCh37
Build 36633,049,803 - 33,050,247RGDNCBI36
Celera634,490,736 - 34,491,180RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,684,357 - 32,684,801UniSTS
CGCbi4-2  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,943,473 - 32,943,846UniSTSGRCh37
Build 36633,051,451 - 33,051,824RGDNCBI36
Celera634,492,384 - 34,492,757RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,686,007 - 32,686,380UniSTS
CGCbpr  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,936,192 - 32,936,479UniSTSGRCh37
Build 36633,044,170 - 33,044,457RGDNCBI36
Celera634,485,104 - 34,485,391RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,678,733 - 32,679,020UniSTS
CGCbx13  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,948,325 - 32,948,669UniSTSGRCh37
Build 36633,056,303 - 33,056,647RGDNCBI36
Celera634,497,238 - 34,497,582RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,690,861 - 32,691,205UniSTS
CGCbx3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,942,221 - 32,942,381UniSTSGRCh37
Build 36633,050,199 - 33,050,359RGDNCBI36
Celera634,491,132 - 34,491,292RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,684,753 - 32,684,913UniSTS
CGCbx4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,943,115 - 32,943,346UniSTSGRCh37
Build 36633,051,093 - 33,051,324RGDNCBI36
Celera634,492,026 - 34,492,257RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,685,649 - 32,685,880UniSTS
CGCbx9  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,945,486 - 32,945,848UniSTSGRCh37
Build 36633,053,464 - 33,053,826RGDNCBI36
Celera634,494,397 - 34,494,759RGD
Cytogenetic Map6p21.3UniSTS
HuRef632,688,020 - 32,688,382UniSTS
BRD2_3857  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,948,364 - 32,949,215UniSTSGRCh37
Build 36633,056,342 - 33,057,193RGDNCBI36
Celera634,497,277 - 34,498,128RGD
HuRef632,690,900 - 32,691,751UniSTS
RING3CA  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,942,887 - 32,943,119UniSTSGRCh37
GRCh37632,942,887 - 32,943,126UniSTSGRCh37
GRCh37632,942,902 - 32,943,119UniSTSGRCh37
Build 36633,050,865 - 33,051,104RGDNCBI36
Celera634,491,798 - 34,492,030UniSTS
Celera634,491,798 - 34,492,037RGD
Celera634,491,813 - 34,492,030UniSTS
HuRef632,685,434 - 32,685,653UniSTS
HuRef632,685,419 - 32,685,660UniSTS
HuRef632,685,419 - 32,685,653UniSTS
RH79050  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37632,943,231 - 32,943,915UniSTSGRCh37
Celera634,492,142 - 34,492,826UniSTS
Cytogenetic Map6p21.3UniSTS
HuRef632,685,765 - 32,686,449UniSTS
GeneMap99-GB4 RH Map6120.15UniSTS
NCBI RH Map6509.1UniSTS




adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2438 2788 2252 4973 1726 2351 6 624 1951 465 2269 7304 6471 53 3734 1 852 1744 1617 175 1


1 to 30 of 94 rows
RefSeq Transcripts NG_042801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001113182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001199455 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001199456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001291986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_005104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047419222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047419223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054329845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054330619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054356162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054356163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001743557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_241911 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF107699 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI983495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK056504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK309797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL645941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL805913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL832722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL935042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY152720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 30 of 94 rows

Ensembl Acc Id: ENST00000374825   ⟹   ENSP00000363958
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,968,594 - 32,981,501 (+)Ensembl
Ensembl Acc Id: ENST00000374831   ⟹   ENSP00000363964
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,970,888 - 32,981,505 (+)Ensembl
Ensembl Acc Id: ENST00000395287   ⟹   ENSP00000378702
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,972,730 - 32,981,505 (+)Ensembl
Ensembl Acc Id: ENST00000449025   ⟹   ENSP00000409613
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,973,084 - 32,981,505 (+)Ensembl
Ensembl Acc Id: ENST00000449085   ⟹   ENSP00000409145
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,969,267 - 32,981,501 (+)Ensembl
Ensembl Acc Id: ENST00000456339   ⟹   ENSP00000411195
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,969,319 - 32,976,618 (+)Ensembl
Ensembl Acc Id: ENST00000463639
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,973,350 - 32,981,323 (+)Ensembl
Ensembl Acc Id: ENST00000464592
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,971,082 - 32,980,815 (+)Ensembl
Ensembl Acc Id: ENST00000469132
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,968,899 - 32,981,286 (+)Ensembl
Ensembl Acc Id: ENST00000481259   ⟹   ENSP00000433751
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,976,569 - 32,977,901 (+)Ensembl
Ensembl Acc Id: ENST00000482838
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,979,682 - 32,980,766 (+)Ensembl
Ensembl Acc Id: ENST00000482914   ⟹   ENSP00000431514
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,970,953 - 32,981,505 (+)Ensembl
Ensembl Acc Id: ENST00000495733   ⟹   ENSP00000436322
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,970,930 - 32,978,197 (+)Ensembl
Ensembl Acc Id: ENST00000496118   ⟹   ENSP00000464077
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,969,165 - 32,972,141 (+)Ensembl
Ensembl Acc Id: ENST00000580234
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,970,238 - 32,972,116 (+)Ensembl
Ensembl Acc Id: ENST00000581002
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,970,902 - 32,972,051 (+)Ensembl
Ensembl Acc Id: ENST00000584808
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,970,705 - 32,972,048 (+)Ensembl
Ensembl Acc Id: ENST00000606059   ⟹   ENSP00000475288
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,976,413 - 32,977,074 (+)Ensembl
Ensembl Acc Id: ENST00000607833   ⟹   ENSP00000475691
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,972,217 - 32,978,203 (+)Ensembl
Ensembl Acc Id: ENST00000677085   ⟹   ENSP00000504779
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,970,246 - 32,981,040 (+)Ensembl
Ensembl Acc Id: ENST00000677331
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,969,278 - 32,980,815 (+)Ensembl
Ensembl Acc Id: ENST00000678250   ⟹   ENSP00000502900
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,969,449 - 32,981,501 (+)Ensembl
Ensembl Acc Id: ENST00000678778   ⟹   ENSP00000503515
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,968,899 - 32,980,779 (+)Ensembl
Ensembl Acc Id: ENST00000679099
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,971,082 - 32,981,040 (+)Ensembl
Ensembl Acc Id: ENST00000679179   ⟹   ENSP00000503678
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl632,968,899 - 32,981,040 (+)Ensembl
RefSeq Acc Id: NM_001113182   ⟹   NP_001106653
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,970,930 - 32,981,501 (+)NCBI
GRCh37632,936,437 - 32,949,282 (+)ENTREZGENE
HuRef632,678,978 - 32,691,818 (+)ENTREZGENE
CHM1_1632,939,470 - 32,950,091 (+)NCBI
T2T-CHM13v2.0632,792,289 - 32,802,867 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001199455   ⟹   NP_001186384
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,971,595 - 32,981,505 (+)NCBI
GRCh37632,936,437 - 32,949,282 (+)ENTREZGENE
HuRef632,678,978 - 32,691,818 (+)ENTREZGENE
CHM1_1632,940,177 - 32,950,091 (+)NCBI
T2T-CHM13v2.0632,792,954 - 32,802,871 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001199456   ⟹   NP_001186385
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,973,084 - 32,981,501 (+)NCBI
GRCh37632,936,437 - 32,949,282 (+)ENTREZGENE
HuRef632,678,978 - 32,691,818 (+)ENTREZGENE
CHM1_1632,941,666 - 32,950,091 (+)NCBI
T2T-CHM13v2.0632,794,443 - 32,802,867 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001291986   ⟹   NP_001278915
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,970,930 - 32,981,501 (+)NCBI
CHM1_1632,939,470 - 32,950,091 (+)NCBI
T2T-CHM13v2.0632,792,289 - 32,802,867 (+)NCBI
Sequence:
RefSeq Acc Id: NM_005104   ⟹   NP_005095
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,968,594 - 32,981,501 (+)NCBI
GRCh37632,936,437 - 32,949,282 (+)ENTREZGENE
Build 36633,044,415 - 33,057,059 (+)NCBI Archive
HuRef632,678,978 - 32,691,818 (+)ENTREZGENE
CHM1_1632,937,242 - 32,950,091 (+)NCBI
T2T-CHM13v2.0632,789,953 - 32,802,867 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047419222   ⟹   XP_047275178
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,970,930 - 32,979,902 (+)NCBI
RefSeq Acc Id: XM_047419223   ⟹   XP_047275179
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,970,930 - 32,977,523 (+)NCBI
RefSeq Acc Id: XM_054356162   ⟹   XP_054212137
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0632,792,289 - 32,801,267 (+)NCBI
RefSeq Acc Id: XM_054356163   ⟹   XP_054212138
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0632,792,289 - 32,798,882 (+)NCBI
1 to 30 of 69 rows
Protein RefSeqs NP_001106653 (Get FASTA)   NCBI Sequence Viewer  
  NP_001186384 (Get FASTA)   NCBI Sequence Viewer  
  NP_001186385 (Get FASTA)   NCBI Sequence Viewer  
  NP_001278915 (Get FASTA)   NCBI Sequence Viewer  
  NP_005095 (Get FASTA)   NCBI Sequence Viewer  
  XP_047275178 (Get FASTA)   NCBI Sequence Viewer  
  XP_047275179 (Get FASTA)   NCBI Sequence Viewer  
  XP_054185819 (Get FASTA)   NCBI Sequence Viewer  
  XP_054185820 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186593 (Get FASTA)   NCBI Sequence Viewer  
  XP_054186594 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187080 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187081 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187344 (Get FASTA)   NCBI Sequence Viewer  
  XP_054187345 (Get FASTA)   NCBI Sequence Viewer  
  XP_054212137 (Get FASTA)   NCBI Sequence Viewer  
  XP_054212138 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA68890 (Get FASTA)   NCBI Sequence Viewer  
  AAD24963 (Get FASTA)   NCBI Sequence Viewer  
  AAH63840 (Get FASTA)   NCBI Sequence Viewer  
  AHW47930 (Get FASTA)   NCBI Sequence Viewer  
  AHW47947 (Get FASTA)   NCBI Sequence Viewer  
  AHW47964 (Get FASTA)   NCBI Sequence Viewer  
  AHW47981 (Get FASTA)   NCBI Sequence Viewer  
  AQY76675 (Get FASTA)   NCBI Sequence Viewer  
  AQY76676 (Get FASTA)   NCBI Sequence Viewer  
  AQY76677 (Get FASTA)   NCBI Sequence Viewer  
  AQY76679 (Get FASTA)   NCBI Sequence Viewer  
  AQY76680 (Get FASTA)   NCBI Sequence Viewer  
  AQY76681 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 69 rows
1 to 5 of 25 rows
1 to 5 of 25 rows
RefSeq Acc Id: NP_005095   ⟸   NM_005104
- Peptide Label: isoform 1
- UniProtKB: Q6P3U2 (UniProtKB/Swiss-Prot),   Q658Y7 (UniProtKB/Swiss-Prot),   Q63HQ9 (UniProtKB/Swiss-Prot),   Q5STC9 (UniProtKB/Swiss-Prot),   Q15310 (UniProtKB/Swiss-Prot),   O00700 (UniProtKB/Swiss-Prot),   O00699 (UniProtKB/Swiss-Prot),   B1AZT1 (UniProtKB/Swiss-Prot),   B0S7P0 (UniProtKB/Swiss-Prot),   A2AAU0 (UniProtKB/Swiss-Prot),   Q969U4 (UniProtKB/Swiss-Prot),   P25440 (UniProtKB/Swiss-Prot),   H0Y6K2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001106653   ⟸   NM_001113182
- Peptide Label: isoform 1
- UniProtKB: Q6P3U2 (UniProtKB/Swiss-Prot),   Q658Y7 (UniProtKB/Swiss-Prot),   Q63HQ9 (UniProtKB/Swiss-Prot),   Q5STC9 (UniProtKB/Swiss-Prot),   Q15310 (UniProtKB/Swiss-Prot),   O00700 (UniProtKB/Swiss-Prot),   O00699 (UniProtKB/Swiss-Prot),   B1AZT1 (UniProtKB/Swiss-Prot),   B0S7P0 (UniProtKB/Swiss-Prot),   A2AAU0 (UniProtKB/Swiss-Prot),   Q969U4 (UniProtKB/Swiss-Prot),   P25440 (UniProtKB/Swiss-Prot),   H0Y6K2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186384   ⟸   NM_001199455
- Peptide Label: isoform 2
- UniProtKB: A0A0G2JK44 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001186385   ⟸   NM_001199456
- Peptide Label: isoform 3
- UniProtKB: X5CF57 (UniProtKB/TrEMBL),   H0Y6K2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278915   ⟸   NM_001291986
- Peptide Label: isoform 4
- UniProtKB: A0A1U9X7A8 (UniProtKB/TrEMBL),   A0A1U9X7B3 (UniProtKB/TrEMBL),   A0A1U9X7B4 (UniProtKB/TrEMBL),   A0A1U9X7B8 (UniProtKB/TrEMBL)
- Sequence:
Bromo   NET

Name Modeler Protein Id AA Range Protein Structure
AF-P25440-F1-model_v2 AlphaFold P25440 1-801 view protein structure

RGD ID:6872868
Promoter ID:EPDNEW_H9574
Type:initiation region
Name:BRD2_3
Description:bromodomain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9575  EPDNEW_H9576  EPDNEW_H9577  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,968,603 - 32,968,663EPDNEW
RGD ID:6872820
Promoter ID:EPDNEW_H9575
Type:initiation region
Name:BRD2_4
Description:bromodomain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9576  EPDNEW_H9577  EPDNEW_H9574  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,969,258 - 32,969,318EPDNEW
RGD ID:6872822
Promoter ID:EPDNEW_H9576
Type:initiation region
Name:BRD2_2
Description:bromodomain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9575  EPDNEW_H9577  EPDNEW_H9574  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,970,937 - 32,970,997EPDNEW
RGD ID:6872824
Promoter ID:EPDNEW_H9577
Type:multiple initiation site
Name:BRD2_1
Description:bromodomain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H9575  EPDNEW_H9576  EPDNEW_H9574  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38632,972,198 - 32,972,258EPDNEW
RGD ID:6803832
Promoter ID:HG_KWN:53142
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_005104,   OTTHUMT00000276543,   OTTHUMT00000276549,   UC010JUG.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,043,296 - 33,044,402 (+)MPROMDB
RGD ID:6805035
Promoter ID:HG_KWN:53144
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000374831,   ENST00000395289,   OTTHUMT00000276546,   OTTHUMT00000276930,   UC003OCO.2,   UC003OCP.2,   UC010JUH.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,045,156 - 33,048,502 (+)MPROMDB
RGD ID:6812913
Promoter ID:HG_ACW:68007
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:BRD2.TAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,049,321 - 33,050,592 (+)MPROMDB
RGD ID:6803808
Promoter ID:HG_KWN:53146
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000276551,   OTTHUMT00000276552
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,050,971 - 33,052,657 (+)MPROMDB
RGD ID:6803807
Promoter ID:HG_KWN:53147
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000276553
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,053,104 - 33,053,604 (+)MPROMDB
RGD ID:6803809
Promoter ID:HG_KWN:53148
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000276547,   OTTHUMT00000276554
Position:
Human AssemblyChrPosition (strand)Source
Build 36633,054,356 - 33,056,127 (+)MPROMDB


1 to 40 of 113 rows
Database
Acc Id
Source(s)
COSMIC BRD2 COSMIC
Ensembl Genes ENSG00000204256 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSG00000215077 UniProtKB/Swiss-Prot
  ENSG00000234507 UniProtKB/Swiss-Prot
  ENSG00000234704 UniProtKB/Swiss-Prot
  ENSG00000235307 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000374825 ENTREZGENE
  ENST00000374825.9 UniProtKB/Swiss-Prot
  ENST00000374831 ENTREZGENE
  ENST00000374831.8 UniProtKB/Swiss-Prot
  ENST00000383108.6 UniProtKB/Swiss-Prot
  ENST00000395287 ENTREZGENE
  ENST00000395287.5 UniProtKB/Swiss-Prot
  ENST00000399527.5 UniProtKB/Swiss-Prot
  ENST00000399528.5 UniProtKB/Swiss-Prot
  ENST00000399529.7 UniProtKB/Swiss-Prot
  ENST00000414731.6 UniProtKB/Swiss-Prot
  ENST00000436979.5 UniProtKB/Swiss-Prot
  ENST00000438194.6 UniProtKB/Swiss-Prot
  ENST00000442863.5 UniProtKB/Swiss-Prot
  ENST00000448067.5 UniProtKB/Swiss-Prot
  ENST00000449025 ENTREZGENE
  ENST00000449085.4 UniProtKB/Swiss-Prot
  ENST00000449118.5 UniProtKB/Swiss-Prot
  ENST00000495733 ENTREZGENE
  ENST00000549126.4 UniProtKB/Swiss-Prot
  ENST00000552587.4 UniProtKB/Swiss-Prot
  ENST00000607833 ENTREZGENE
  ENST00000678250.1 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1270.220 UniProtKB/Swiss-Prot
  1.20.920.10 UniProtKB/Swiss-Prot
GTEx ENSG00000204256 GTEx
  ENSG00000215077 GTEx
  ENSG00000234507 GTEx
  ENSG00000234704 GTEx
  ENSG00000235307 GTEx
HGNC ID HGNC:1103 ENTREZGENE
Human Proteome Map BRD2 Human Proteome Map
InterPro Bromo_Brdt_I UniProtKB/Swiss-Prot
  Bromo_Brdt_II UniProtKB/Swiss-Prot
1 to 40 of 113 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-01-20 BRD2  bromodomain containing 2  BRD2-IT1  BRD2 intronic transcript 1  Data merged from RGD:10413065 737654 PROVISIONAL