Gene: Homer1 (homer scaffold protein 1) Rattus norvegicus
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Symbol: Homer1
Name: homer scaffold protein 1
Description: ENCODES a protein that exhibits G protein-coupled glutamate receptor binding; identical protein binding; molecular adaptor activity; INVOLVED IN circadian rhythm; G protein-coupled glutamate receptor signaling pathway; protein localization to synapse; PARTICIPATES IN glutamate signaling pathway; ASSOCIATED WITH Cocaine-Related Disorders (ortholog); Drug-Induced Dyskinesia (ortholog); Drug-Related Side Effects and Adverse Reactions (ortholog); FOUND IN dendrite; dendritic shaft; excitatory synapse; INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 3H-1,2-dithiole-3-thione
AGR Description: Exhibits several functions, including identical protein binding activity, protein heterodimerization activity, and scaffold protein binding activity; involved in several processes, including G protein-coupled glutamate receptor signaling pathway, circadian rhythm, and protein localization to synapse; localizes to several cellular components, including the glutamatergic synapse, neuron projection, and neuronal cell body; colocalizes with the excitatory synapse; orthologous to human HOMER1 (homer scaffold protein 1).
Merged Description: Exhibits several functions, including identical protein binding activity, protein heterodimerization activity, and scaffold protein binding activity; involved in several processes, including G protein-coupled glutamate receptor signaling pathway, circadian rhythm, and protein localization to synapse; localizes to several cellular components, including the glutamatergic synapse, neuron projection, and neuronal cell body; colocalizes with the excitatory synapse; orthologous to human HOMER1 (homer scaffold protein 1); PARTICIPATES IN glutamate signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 17beta-estradiol; 3H-1,2-dithiole-3-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: homer homolog 1; homer homolog 1 (Drosophila); homer protein homolog 1; homer scaffolding protein 1; homer, neuronal immediate early gene, 1; HOMER1F; PSD-Zip45; scaffold protein; VASP/Ena-related gene up-regulated during seizure and LTP 1; Vesl-1
Orthologs:
Homo sapiens (human) : HOMER1 (homer scaffold protein 1)  HGNC  Alliance
Mus musculus (house mouse) : Homer1 (homer scaffolding protein 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Homer1 (homer scaffold protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HOMER1 (homer scaffold protein 1)
Canis lupus familiaris (dog) : HOMER1 (homer scaffold protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Homer1 (homer scaffold protein 1)
Sus scrofa (pig) : HOMER1 (homer scaffold protein 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0222,909,550 - 23,012,303 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0242,106,531 - 42,208,187 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera220,619,882 - 20,720,929 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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QTLs in Region (Rnor_6.0)
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Sequence

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Strain Sequence Variants (Rnor 5.0)

Additional Information

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Nomenclature History
RGD Curation Notes
 
More on Homer1
Alliance Gene
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 628725
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.