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Gene: Bmi1 (BMI1 proto-oncogene, polycomb ring finger) Rattus norvegicus
Symbol: Bmi1
Name: BMI1 proto-oncogene, polycomb ring finger
Description: Predicted to have several functions, including RING-like zinc finger domain binding activity; promoter-specific chromatin binding activity; and ubiquitin-protein transferase activator activity. Involved in cellular response to dexamethasone stimulus and cellular response to interleukin-1. Predicted to localize to cytosol; heterochromatin; and nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia; colorectal carcinoma; and hepatocellular carcinoma. Orthologous to several human genes including COMMD3-BMI1 (COMMD3-BMI1 readthrough); PARTICIPATES IN histone modification pathway; INTERACTS WITH amphetamine; bisphenol A; cadmium dichloride.
Type: protein-coding
Also known as: B lymphoma Mo-MLV insertion region 1; Bmi1 polycomb ring finger oncogene; LOC307151; Pcgf4; polycomb complex protein BMI-1; polycomb group ring finger 4
Homo sapiens (human) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)  HGNC  Alliance
Mus musculus (house mouse) : Bmi1 (Bmi1 polycomb ring finger oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmi1 (BMI1 proto-oncogene, polycomb ring finger)
Pan paniscus (bonobo/pygmy chimpanzee) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)
Canis lupus familiaris (dog) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)
Sus scrofa (pig) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)
Chlorocebus sabaeus (African green monkey) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)
Heterocephalus glaber (naked mole-rat) : Bmi1 (BMI1 proto-oncogene, polycomb ring finger)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01785,360,439 - 85,370,283 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1785,364,483 - 85,368,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01787,087,687 - 87,091,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41792,784,216 - 92,787,947 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11792,795,131 - 92,798,710 (+)NCBI
Celera1780,616,376 - 80,620,118 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Bmi1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307403
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.