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Gene: Bmi1 (BMI1 proto-oncogene, polycomb ring finger) Rattus norvegicus
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Symbol: Bmi1
Name: BMI1 proto-oncogene, polycomb ring finger
Description: Predicted to have several functions, including RING-like zinc finger domain binding activity; promoter-specific chromatin binding activity; and ubiquitin-protein transferase activator activity. Involved in cellular response to dexamethasone stimulus and cellular response to interleukin-1. Predicted to localize to cytosol; heterochromatin; and nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia; colorectal carcinoma; and hepatocellular carcinoma. Orthologous to several human genes including COMMD3-BMI1 (COMMD3-BMI1 readthrough); PARTICIPATES IN histone modification pathway; INTERACTS WITH amphetamine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: B lymphoma Mo-MLV insertion region 1; Bmi1 polycomb ring finger oncogene; LOC307151; Pcgf4; polycomb complex protein BMI-1; polycomb group ring finger 4
Orthologs:
Homo sapiens (human) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)  HGNC  Alliance
Mus musculus (house mouse) : Bmi1 (Bmi1 polycomb ring finger oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bmi1 (BMI1 proto-oncogene, polycomb ring finger)
Pan paniscus (bonobo/pygmy chimpanzee) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)
Canis lupus familiaris (dog) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)
Sus scrofa (pig) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)
Chlorocebus sabaeus (African green monkey) : BMI1 (BMI1 proto-oncogene, polycomb ring finger)
Heterocephalus glaber (naked mole-rat) : Bmi1 (BMI1 proto-oncogene, polycomb ring finger)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01785,360,439 - 85,370,283 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1785,364,483 - 85,368,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01787,087,687 - 87,091,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41792,784,216 - 92,787,947 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11792,795,131 - 92,798,710 (+)NCBI
Celera1780,616,376 - 80,620,118 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Bmi1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307403
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.