Bmi1 (BMI1 proto-oncogene, polycomb ring finger) - Rat Genome Database

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Gene: Bmi1 (BMI1 proto-oncogene, polycomb ring finger) Heterocephalus glaber
Analyze
Symbol: Bmi1
Name: BMI1 proto-oncogene, polycomb ring finger
RGD ID: 18922052
Description: ENCODES a protein that exhibits chromatin binding (ortholog); RING-like zinc finger domain binding (ortholog); ubiquitin-protein transferase activator activity (ortholog); INVOLVED IN apoptotic signaling pathway (ortholog); brain development (ortholog); cellular response to dexamethasone stimulus (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH acute myeloid leukemia (ortholog); acute pancreatitis (ortholog); Chronic Pancreatitis (ortholog); FOUND IN cytosol (ortholog); heterochromatin (ortholog); nuclear body (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BMI1 polycomb ring finger oncogene; Polycomb complex protein BMI-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247966,274,561 - 6,282,984 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247966,277,201 - 6,282,830 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Bmi1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247966,274,561 - 6,282,984 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247966,277,201 - 6,282,830 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
BMI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381022,321,099 - 22,331,706 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1022,321,099 - 22,331,484 (+)EnsemblGRCh38hg38GRCh38
GRCh371022,610,028 - 22,620,413 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361022,650,146 - 22,660,194 (+)NCBINCBI36Build 36hg18NCBI36
Build 341022,650,145 - 22,660,190NCBI
Celera1022,297,715 - 22,308,139 (+)NCBICelera
Cytogenetic Map10p12.2NCBI
HuRef1022,276,563 - 22,281,617 (+)NCBIHuRef
CHM1_11022,610,777 - 22,620,864 (+)NCBICHM1_1
T2T-CHM13v2.01022,340,133 - 22,350,740 (+)NCBIT2T-CHM13v2.0
Bmi1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39218,681,953 - 18,691,440 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl218,681,829 - 18,691,440 (+)EnsemblGRCm39 Ensembl
GRCm38218,677,018 - 18,686,629 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl218,677,018 - 18,686,629 (+)EnsemblGRCm38mm10GRCm38
MGSCv37218,598,645 - 18,608,256 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36218,594,772 - 18,604,383 (+)NCBIMGSCv36mm8
Celera218,564,450 - 18,578,495 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map212.9NCBI
Bmi1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81786,240,683 - 86,250,044 (+)NCBIGRCr8
mRatBN7.21781,332,175 - 81,341,625 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1781,332,214 - 81,388,690 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1784,809,066 - 84,812,740 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01788,644,466 - 88,648,140 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01782,661,208 - 82,664,882 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01785,360,439 - 85,370,283 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1785,364,483 - 85,368,208 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01787,087,687 - 87,091,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41792,784,216 - 92,787,947 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11792,795,131 - 92,798,710 (+)NCBI
Celera1780,616,376 - 80,620,118 (+)NCBICelera
Cytogenetic Map17q12.3NCBI
Bmi1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554296,547,731 - 6,558,105 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554296,548,586 - 6,553,730 (-)NCBIChiLan1.0ChiLan1.0
BMI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2835,001,734 - 35,011,206 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11035,006,599 - 35,016,531 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01022,477,755 - 22,487,894 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11022,854,230 - 22,863,482 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1022,857,776 - 22,863,479 (+)Ensemblpanpan1.1panPan2
BMI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1210,818,232 - 10,828,473 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl210,818,232 - 10,833,613 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha29,511,530 - 9,521,768 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.029,018,100 - 9,028,340 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl29,018,100 - 9,033,607 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.128,381,805 - 8,392,033 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.028,465,970 - 8,476,210 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.028,633,839 - 8,644,069 (-)NCBIUU_Cfam_GSD_1.0
Bmi1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934422,243,467 - 22,253,222 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365205,707,778 - 5,717,024 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365205,707,542 - 5,716,966 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BMI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1052,586,509 - 52,596,564 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11052,586,089 - 52,596,154 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21058,240,742 - 58,245,839 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BMI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1922,095,592 - 22,104,894 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605127,837,839 - 27,848,269 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000005786   ⟹   ENSHGLP00000005714
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247966,274,561 - 6,282,984 (-)Ensembl
RefSeq Acc Id: XM_004859926   ⟹   XP_004859983
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247966,279,117 - 6,282,830 (-)NCBI
RefSeq Acc Id: XM_013077869   ⟹   XP_012933323
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247966,277,201 - 6,282,191 (-)NCBI
RefSeq Acc Id: XM_013077871   ⟹   XP_012933325
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247966,277,201 - 6,282,507 (-)NCBI
RefSeq Acc Id: XM_021240449   ⟹   XP_021096108
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247966,277,201 - 6,282,191 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004859983 (Get FASTA)   NCBI Sequence Viewer  
  XP_012933323 (Get FASTA)   NCBI Sequence Viewer  
  XP_012933325 (Get FASTA)   NCBI Sequence Viewer  
  XP_021096108 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB12617 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005714
  ENSHGLP00000056603
  ENSHGLP00100032258
RefSeq Acc Id: XP_012933325   ⟸   XM_013077871
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021096108   ⟸   XM_021240449
- Peptide Label: isoform X2
RefSeq Acc Id: XP_012933323   ⟸   XM_013077869
- Peptide Label: isoform X1
- UniProtKB: G5BTK4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004859983   ⟸   XM_004859926
- Peptide Label: isoform X1
- UniProtKB: G5BTK4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000005714   ⟸   ENSHGLT00000005786


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004175 Ensembl, ENTREZGENE
  ENSHGLG00000032421 UniProtKB/TrEMBL
  ENSHGLG00100046688 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000005786 ENTREZGENE
  ENSHGLT00000057047 UniProtKB/TrEMBL
  ENSHGLT00100089898 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro RAWUL UniProtKB/TrEMBL
  Znf_RING UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_RING_CS UniProtKB/TrEMBL
KEGG Report hgl:101705973 UniProtKB/TrEMBL
NCBI Gene Bmi1 ENTREZGENE
PANTHER POLYCOMB COMPLEX PROTEIN BMI-1 UniProtKB/TrEMBL
  RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT UniProtKB/TrEMBL
Pfam RAWUL UniProtKB/TrEMBL
  zf-C3HC4_2 UniProtKB/TrEMBL
PROSITE ZF_RING_1 UniProtKB/TrEMBL
  ZF_RING_2 UniProtKB/TrEMBL
SMART RING UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt G5BTK4 ENTREZGENE, UniProtKB/TrEMBL