Cdk10 (cyclin-dependent kinase 10) - Rat Genome Database

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Gene: Cdk10 (cyclin-dependent kinase 10) Rattus norvegicus
Analyze
Symbol: Cdk10
Name: cyclin-dependent kinase 10
RGD ID: 1304851
Description: Predicted to enable cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in several processes, including peptidyl-threonine phosphorylation; regulation of cell cycle G2/M phase transition; and regulation of organelle organization. Predicted to act upstream of or within positive regulation of MAPK cascade. Predicted to be located in ciliary basal body. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in nucleus. Orthologous to human CDK10 (cyclin dependent kinase 10); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: cell division protein kinase 10; cyclin-dependent kinase (CDC2-like) 10; LOC361434; MGC112847
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21951,260,012 - 51,273,009 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1951,261,356 - 51,269,078 (+)Ensembl
Rnor_6.01956,024,903 - 56,032,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,024,903 - 56,032,605 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,728,927 - 66,738,144 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,545,204 - 53,552,911 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11953,551,287 - 53,557,788 (+)NCBI
Celera1950,497,238 - 50,504,945 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:11006117   PMID:12477932   PMID:15489334   PMID:16751776   PMID:24218572   PMID:27104747  


Genomics

Comparative Map Data
Cdk10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21951,260,012 - 51,273,009 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1951,261,356 - 51,269,078 (+)Ensembl
Rnor_6.01956,024,903 - 56,032,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1956,024,903 - 56,032,605 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01966,728,927 - 66,738,144 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41953,545,204 - 53,552,911 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11953,551,287 - 53,557,788 (+)NCBI
Celera1950,497,238 - 50,504,945 (+)NCBICelera
Cytogenetic Map19q12NCBI
CDK10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,686,689 - 89,696,354 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1689,680,737 - 89,696,354 (+)EnsemblGRCh38hg38GRCh38
GRCh371689,753,097 - 89,762,762 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361688,280,577 - 88,290,263 (+)NCBINCBI36hg18NCBI36
Build 341688,280,578 - 88,290,262NCBI
Celera1674,817,511 - 74,827,207 (+)NCBI
Cytogenetic Map16q24.3NCBI
HuRef1675,448,350 - 75,458,046 (+)NCBIHuRef
CHM1_11691,164,300 - 91,173,997 (+)NCBICHM1_1
T2T-CHM13v2.01695,771,455 - 95,781,117 (+)NCBI
Cdk10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398123,951,580 - 123,958,995 (+)NCBIGRCm39mm39
GRCm39 Ensembl8123,951,581 - 123,958,989 (+)Ensembl
GRCm388123,224,841 - 123,232,256 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8123,224,842 - 123,232,250 (+)EnsemblGRCm38mm10GRCm38
MGSCv378125,748,741 - 125,756,156 (+)NCBIGRCm37mm9NCBIm37
MGSCv368126,110,931 - 126,118,344 (+)NCBImm8
Celera8127,463,881 - 127,471,305 (+)NCBICelera
Cytogenetic Map8E1NCBI
Cdk10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555413,235,448 - 3,242,377 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555413,235,441 - 3,242,377 (+)NCBIChiLan1.0ChiLan1.0
CDK10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11690,109,448 - 90,120,119 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1690,109,492 - 90,119,532 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01670,445,200 - 70,455,476 (+)NCBIMhudiblu_PPA_v0panPan3
CDK10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1563,878,517 - 63,897,540 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl563,879,024 - 63,897,373 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha563,891,370 - 63,910,420 (-)NCBI
ROS_Cfam_1.0564,106,299 - 64,125,413 (-)NCBI
ROS_Cfam_1.0 Ensembl564,106,305 - 64,125,222 (-)Ensembl
UMICH_Zoey_3.1564,126,411 - 64,145,475 (-)NCBI
UNSW_CanFamBas_1.0563,964,013 - 63,983,067 (-)NCBI
UU_Cfam_GSD_1.0564,370,590 - 64,389,641 (-)NCBI
Cdk10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934924,598,384 - 24,606,038 (-)NCBI
SpeTri2.0NW_004936641351,905 - 359,553 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6332,242 - 339,142 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16332,239 - 339,130 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26458,803 - 465,827 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDK10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1575,002,284 - 75,034,555 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl575,024,205 - 75,033,428 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666047460,826 - 472,086 (-)NCBIVero_WHO_p1.0
Cdk10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624746281,092 - 291,026 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_004624746285,006 - 291,019 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH132209  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,260,621 - 51,260,819 (+)MAPPERmRatBN7.2
Rnor_6.01956,024,152 - 56,024,349NCBIRnor6.0
Rnor_5.01966,729,025 - 66,729,222UniSTSRnor5.0
RGSC_v3.41953,544,453 - 53,544,650UniSTSRGSC3.4
Celera1950,496,487 - 50,496,684UniSTS
RH 3.4 Map19710.21UniSTS
Cytogenetic Map19q12UniSTS
RH141043  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21951,268,827 - 51,269,043 (+)MAPPERmRatBN7.2
Rnor_6.01956,032,357 - 56,032,572NCBIRnor6.0
Rnor_5.01966,737,230 - 66,737,445UniSTSRnor5.0
RGSC_v3.41953,552,658 - 53,552,873UniSTSRGSC3.4
Celera1950,504,692 - 50,504,907UniSTS
RH 3.4 Map19712.01UniSTS
Cytogenetic Map19q12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193383821455283146Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat
2313395Anxrr26Anxiety related response QTL 26aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)194997648153225766Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:528
Count of miRNA genes:178
Interacting mature miRNAs:196
Transcripts:ENSRNOT00000021607, ENSRNOT00000066552
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 57 41 19 41 1 4 74 35 41 11 1
Low 8 7 7 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001025722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001109936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001109937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097884 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039097887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005496671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI071224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC098804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN932869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN935585 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ607073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY320517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000021607   ⟹   ENSRNOP00000021607
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1951,261,356 - 51,269,077 (+)Ensembl
Rnor_6.0 Ensembl1956,024,903 - 56,032,605 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000066552   ⟹   ENSRNOP00000059465
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1951,262,576 - 51,269,078 (+)Ensembl
Rnor_6.0 Ensembl1956,026,106 - 56,032,605 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099003   ⟹   ENSRNOP00000077813
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1951,262,576 - 51,269,078 (+)Ensembl
RefSeq Acc Id: NM_001025722   ⟹   NP_001020893
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,262,576 - 51,269,081 (+)NCBI
Rnor_6.01956,026,106 - 56,032,610 (+)NCBI
Rnor_5.01966,728,927 - 66,738,144 (+)NCBI
RGSC_v3.41953,545,204 - 53,552,911 (+)RGD
Celera1950,498,441 - 50,504,945 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001109936   ⟹   NP_001103406
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,261,373 - 51,269,081 (+)NCBI
Rnor_6.01956,024,903 - 56,032,610 (+)NCBI
Rnor_5.01966,728,927 - 66,738,144 (+)NCBI
RGSC_v3.41953,545,204 - 53,552,911 (+)RGD
Celera1950,497,238 - 50,504,945 (+)RGD
Sequence:
RefSeq Acc Id: NM_001109937   ⟹   NP_001103407
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,261,374 - 51,269,081 (+)NCBI
Rnor_6.01956,024,904 - 56,032,610 (+)NCBI
Rnor_5.01966,728,927 - 66,738,144 (+)NCBI
RGSC_v3.41953,545,204 - 53,552,911 (+)RGD
Celera1950,497,239 - 50,504,945 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097881   ⟹   XP_038953809
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,262,764 - 51,269,077 (+)NCBI
RefSeq Acc Id: XM_039097882   ⟹   XP_038953810
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,260,488 - 51,269,079 (+)NCBI
RefSeq Acc Id: XM_039097883   ⟹   XP_038953811
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,261,252 - 51,273,009 (+)NCBI
RefSeq Acc Id: XM_039097884   ⟹   XP_038953812
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,260,021 - 51,268,513 (+)NCBI
RefSeq Acc Id: XM_039097885   ⟹   XP_038953813
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,261,413 - 51,269,077 (+)NCBI
RefSeq Acc Id: XM_039097886   ⟹   XP_038953814
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,261,392 - 51,269,077 (+)NCBI
RefSeq Acc Id: XM_039097887   ⟹   XP_038953815
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,260,499 - 51,269,079 (+)NCBI
RefSeq Acc Id: XR_005496671
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21951,260,012 - 51,267,709 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001020893   ⟸   NM_001025722
- Peptide Label: isoform 3
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot),   F1LSV8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103406   ⟸   NM_001109936
- Peptide Label: isoform 1
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot),   G3V814 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001103407   ⟸   NM_001109937
- Peptide Label: isoform 2
- UniProtKB: Q4KM47 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000021607   ⟸   ENSRNOT00000021607
RefSeq Acc Id: ENSRNOP00000059465   ⟸   ENSRNOT00000066552
RefSeq Acc Id: XP_038953812   ⟸   XM_039097884
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038953810   ⟸   XM_039097882
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038953815   ⟸   XM_039097887
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038953811   ⟸   XM_039097883
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038953814   ⟸   XM_039097886
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038953813   ⟸   XM_039097885
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038953809   ⟸   XM_039097881
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000077813   ⟸   ENSRNOT00000099003
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KM47-F1-model_v2 AlphaFold Q4KM47 1-358 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701221
Promoter ID:EPDNEW_R11745
Type:multiple initiation site
Name:Cdk10_1
Description:cyclin-dependent kinase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01956,024,896 - 56,024,956EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304851 AgrOrtholog
BioCyc Gene G2FUF-5335 BioCyc
Ensembl Genes ENSRNOG00000016088 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000021607 ENTREZGENE
  ENSRNOP00000021607.4 UniProtKB/TrEMBL
  ENSRNOP00000059465 ENTREZGENE
  ENSRNOP00000059465.1 UniProtKB/TrEMBL
  ENSRNOP00000077813.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021607 ENTREZGENE
  ENSRNOT00000021607.9 UniProtKB/TrEMBL
  ENSRNOT00000066552 ENTREZGENE
  ENSRNOT00000066552.4 UniProtKB/TrEMBL
  ENSRNOT00000099003.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7376321 IMAGE-MGC_LOAD
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STKc_CDK10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361434 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:112847 IMAGE-MGC_LOAD
NCBI Gene 361434 ENTREZGENE
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cdk10 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y1M3_RAT UniProtKB/TrEMBL
  CDK10_RAT UniProtKB/Swiss-Prot
  F1LSV8 ENTREZGENE, UniProtKB/TrEMBL
  G3V814 ENTREZGENE, UniProtKB/TrEMBL
  Q4KM47 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-29 Cdk10  cyclin-dependent kinase 10  Cdk10  cyclin-dependent kinase (CDC2-like) 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Cdk10  cyclin-dependent kinase (CDC2-like) 10  Cdk10_predicted  cyclin-dependent kinase (CDC2-like) 10 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Cdk10_predicted  cyclin-dependent kinase (CDC2-like) 10 (predicted)      Symbol and Name status set to approved 70820 APPROVED