Lpcat1 (lysophosphatidylcholine acyltransferase 1) - Rat Genome Database

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Gene: Lpcat1 (lysophosphatidylcholine acyltransferase 1) Rattus norvegicus
Analyze
Symbol: Lpcat1
Name: lysophosphatidylcholine acyltransferase 1
RGD ID: 1311599
Description: Enables 1-acylglycerol-3-phosphate O-acyltransferase activity and 1-acylglycerophosphocholine O-acyltransferase activity. Predicted to be involved in phosphatidylcholine acyl-chain remodeling and phospholipid biosynthetic process. Predicted to act upstream of or within several processes, including negative regulation of phosphatidylcholine biosynthetic process; positive regulation of protein catabolic process; and surfactant homeostasis. Predicted to be located in Golgi apparatus; lipid droplet; and membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human LPCAT1 (lysophosphatidylcholine acyltransferase 1); PARTICIPATES IN ether lipid metabolic pathway; ether lipid metabolic pathway; glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1-acylglycerol-3-phosphate O-acyltransferase; 1-acylglycerophosphocholine O-acyltransferase; 1-alkenylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; acetyl-CoA:lyso-PAF acetyltransferase; acetyl-CoA:lyso-platelet-activating factor acetyltransferase; acyltransferase like 2; acyltransferase-like 2; Aytl2; LOC361467; LPC acyltransferase 1; LPCAT-1; lyso-PAF acetyltransferase; lysoPAFAT; lysoPC acyltransferase 1; RGD1311599; similar to hypothetical protein FLJ20481
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8131,594,621 - 31,644,946 (-)NCBIGRCr8
mRatBN7.2129,766,070 - 29,816,401 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,766,071 - 29,816,401 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx129,567,204 - 29,617,533 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0135,567,047 - 35,617,376 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,767,829 - 29,818,157 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0132,379,431 - 32,429,917 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl132,379,432 - 32,429,917 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,802,632 - 33,853,118 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4130,573,254 - 30,624,147 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1130,576,204 - 30,627,092 (-)NCBI
Celera128,412,898 - 28,463,109 (-)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (EXP,ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
butyric acid  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
ciglitazone  (ISO)
cobalt dichloride  (EXP,ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
fucoxanthin  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glucose  (ISO)
glyphosate  (EXP)
imidacloprid  (EXP)
indometacin  (ISO)
irinotecan  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
lithocholic acid  (ISO)
methapyrilene  (ISO)
methyl methanesulfonate  (ISO)
nickel sulfate  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paraquat  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
thiabendazole  (EXP)
thifluzamide  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells. Chen X, etal., Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11724-9. doi: 10.1073/pnas.0604946103. Epub 2006 Jul 24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:15057822   PMID:16704971   PMID:18156367   PMID:18285344   PMID:19946888   PMID:20018880   PMID:21052544   PMID:21498505   PMID:22296727  


Genomics

Comparative Map Data
Lpcat1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8131,594,621 - 31,644,946 (-)NCBIGRCr8
mRatBN7.2129,766,070 - 29,816,401 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl129,766,071 - 29,816,401 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx129,567,204 - 29,617,533 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0135,567,047 - 35,617,376 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0129,767,829 - 29,818,157 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0132,379,431 - 32,429,917 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl132,379,432 - 32,429,917 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,802,632 - 33,853,118 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4130,573,254 - 30,624,147 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1130,576,204 - 30,627,092 (-)NCBI
Celera128,412,898 - 28,463,109 (-)NCBICelera
Cytogenetic Map1p11NCBI
LPCAT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3851,461,427 - 1,523,960 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl51,456,480 - 1,523,962 (-)EnsemblGRCh38hg38GRCh38
GRCh3751,461,542 - 1,524,075 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3651,514,542 - 1,577,076 (-)NCBINCBI36Build 36hg18NCBI36
Celera51,499,585 - 1,562,101 (-)NCBICelera
Cytogenetic Map5p15.33NCBI
HuRef51,442,770 - 1,505,328 (-)NCBIHuRef
CHM1_151,461,370 - 1,523,947 (-)NCBICHM1_1
T2T-CHM13v2.051,373,271 - 1,435,654 (-)NCBIT2T-CHM13v2.0
Lpcat1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391373,615,332 - 73,664,539 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1373,615,316 - 73,664,541 (+)EnsemblGRCm39 Ensembl
GRCm381373,467,231 - 73,516,420 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1373,467,197 - 73,516,422 (+)EnsemblGRCm38mm10GRCm38
MGSCv371373,604,831 - 73,651,986 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361373,933,228 - 73,982,413 (+)NCBIMGSCv36mm8
Celera1375,795,573 - 75,842,729 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1339.97NCBI
Lpcat1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955504758,881 - 791,996 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955504760,941 - 791,996 (-)NCBIChiLan1.0ChiLan1.0
LPCAT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v241,732,113 - 1,797,068 (-)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl51,503,853 - 1,544,741 (-)Ensemblpanpan1.1panPan2
LPCAT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13411,162,715 - 11,195,380 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3411,164,615 - 11,193,681 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3415,658,942 - 15,705,323 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03411,049,553 - 11,095,789 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3411,049,271 - 11,095,790 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13411,100,715 - 11,147,111 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03411,079,852 - 11,126,208 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03411,290,686 - 11,337,070 (+)NCBIUU_Cfam_GSD_1.0
Lpcat1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213244,130,919 - 244,184,633 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936815292,200 - 344,413 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936815281,664 - 345,915 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LPCAT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1679,134,465 - 79,173,772 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11679,134,396 - 79,173,775 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21685,797,427 - 85,837,645 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LPCAT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.141,273,542 - 1,333,840 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl41,275,769 - 1,333,801 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605435,841,315 - 35,902,916 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lpcat1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624751730,472 - 764,430 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624751732,364 - 764,421 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lpcat1
159 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:446
Count of miRNA genes:237
Interacting mature miRNAs:306
Transcripts:ENSRNOT00000024111
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)11148148232355910Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)12076315844095856Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1224439043433040Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 21 78 105 66 64 66 249 66 103 55
Low 63 122 81 5 81 36 45 49 42 24
Below cutoff

Sequence


Ensembl Acc Id: ENSRNOT00000024111   ⟹   ENSRNOP00000024111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,766,071 - 29,816,401 (-)Ensembl
Rnor_6.0 Ensembl132,379,432 - 32,429,917 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108874   ⟹   ENSRNOP00000086508
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl129,766,071 - 29,803,247 (-)Ensembl
RefSeq Acc Id: NM_001100735   ⟹   NP_001094205
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8131,594,621 - 31,644,946 (-)NCBI
mRatBN7.2129,766,070 - 29,816,401 (-)NCBI
Rnor_6.0132,379,431 - 32,429,917 (-)NCBI
Rnor_5.0133,802,632 - 33,853,118 (-)NCBI
RGSC_v3.4130,573,254 - 30,624,147 (-)RGD
Celera128,412,898 - 28,463,109 (-)RGD
Sequence:
RefSeq Acc Id: XM_039081212   ⟹   XP_038937140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8131,594,621 - 31,644,815 (-)NCBI
mRatBN7.2129,766,070 - 29,816,263 (-)NCBI
RefSeq Acc Id: NP_001094205   ⟸   NM_001100735
- UniProtKB: Q1HAQ0 (UniProtKB/Swiss-Prot),   A6JUX7 (UniProtKB/TrEMBL),   A0A8I6A2C9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000024111   ⟸   ENSRNOT00000024111
RefSeq Acc Id: XP_038937140   ⟸   XM_039081212
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A2C9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000086508   ⟸   ENSRNOT00000108874
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q1HAQ0-F1-model_v2 AlphaFold Q1HAQ0 1-534 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689569
Promoter ID:EPDNEW_R94
Type:initiation region
Name:Lpcat1_1
Description:lysophosphatidylcholine acyltransferase 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0132,429,912 - 32,429,972EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311599 AgrOrtholog
BioCyc Gene G2FUF-61923 BioCyc
BioCyc Pathway PWY-7409 [phospholipid remodeling (phosphatidylethanolamine, yeast)] BioCyc
  PWY-7416 [phospholipid remodeling (phosphatidylcholine, yeast)] BioCyc
BioCyc Pathway Image PWY-7409 BioCyc
  PWY-7416 BioCyc
Ensembl Genes ENSRNOG00000017930 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055003029 UniProtKB/Swiss-Prot
  ENSRNOG00060025843 UniProtKB/Swiss-Prot
  ENSRNOG00065018838 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000024111.6 UniProtKB/Swiss-Prot
  ENSRNOT00000108874.1 UniProtKB/TrEMBL
  ENSRNOT00055004720 UniProtKB/Swiss-Prot
  ENSRNOT00060044768 UniProtKB/Swiss-Prot
  ENSRNOT00065031647 UniProtKB/Swiss-Prot
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LPCAT1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Plipid/glycerol_acylTrfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361467 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 361467 ENTREZGENE
PANTHER LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PHOSPHOLIPID ACYLTRANSFERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lpcat1 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017930 RatGTEx
  ENSRNOG00055003029 RatGTEx
  ENSRNOG00060025843 RatGTEx
  ENSRNOG00065018838 RatGTEx
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PlsC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glycerol-3-phosphate (1)-acyltransferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A2C9 ENTREZGENE, UniProtKB/TrEMBL
  A6JUX7 ENTREZGENE, UniProtKB/TrEMBL
  PCAT1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-10 Lpcat1  lysophosphatidylcholine acyltransferase 1  Aytl2_predicted  acyltransferase like 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Aytl2_predicted  acyltransferase like 2 (predicted)  RGD1311599_predicted  similar to hypothetical protein FLJ20481 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1311599_predicted  similar to hypothetical protein FLJ20481 (predicted)  LOC361467_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC361467_predicted  similar to hypothetical protein FLJ20481 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL