Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Lpcat1 (lysophosphatidylcholine acyltransferase 1) Rattus norvegicus
Symbol: Lpcat1
Name: lysophosphatidylcholine acyltransferase 1
RGD ID: 1311599
Description: Exhibits 1-acylglycerol-3-phosphate O-acyltransferase activity and 1-acylglycerophosphocholine O-acyltransferase activity. Predicted to be involved in several processes, including negative regulation of phosphatidylcholine biosynthetic process; phospholipid metabolic process; and surfactant homeostasis. Predicted to localize to Golgi apparatus; endoplasmic reticulum; and lipid droplet. Orthologous to human LPCAT1 (lysophosphatidylcholine acyltransferase 1); PARTICIPATES IN ether lipid metabolic pathway; ether lipid metabolic pathway; glycerophospholipid metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1-acylglycerol-3-phosphate O-acyltransferase; 1-acylglycerophosphocholine O-acyltransferase; 1-alkenylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; acetyl-CoA:lyso-PAF acetyltransferase; acetyl-CoA:lyso-platelet-activating factor acetyltransferase; acyltransferase like 2; acyltransferase-like 2; Aytl2; LOC361467; LPC acyltransferase 1; LPCAT-1; lyso-PAF acetyltransferase; lysoPAFAT; lysoPC acyltransferase 1; RGD1311599; similar to hypothetical protein FLJ20481
Homo sapiens (human) : LPCAT1 (lysophosphatidylcholine acyltransferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Lpcat1 (lysophosphatidylcholine acyltransferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lpcat1 (lysophosphatidylcholine acyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LPCAT1 (lysophosphatidylcholine acyltransferase 1)
Canis lupus familiaris (dog) : LPCAT1 (lysophosphatidylcholine acyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lpcat1 (lysophosphatidylcholine acyltransferase 1)
Sus scrofa (pig) : LPCAT1 (lysophosphatidylcholine acyltransferase 1)
Chlorocebus sabaeus (African green monkey) : LPCAT1 (lysophosphatidylcholine acyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Lpcat1 (lysophosphatidylcholine acyltransferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0132,379,431 - 32,429,917 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl132,379,432 - 32,429,917 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0133,802,632 - 33,853,118 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4130,573,254 - 30,624,147 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1130,576,204 - 30,627,092 (-)NCBI
Celera128,412,898 - 28,463,109 (-)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Lpcat1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311599
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.