Psmb9 (proteasome subunit beta 9)

Gene: Psmb9 (proteasome subunit beta 9) Rattus norvegicus

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Symbol:

Psmb9

Name:

proteasome subunit beta 9

Description:

Exhibits proteasome binding activity. Involved in several processes, including cellular response to electrical stimulus; hematopoietic or lymphoid organ development; and response to benzene. Localizes to the cytosol and proteasome complex. Biomarker of breast carcinoma and peptic esophagitis. Human ortholog(s) of this gene implicated in ankylosing spondylitis; autoimmune hypersensitivity disease (multiple); lymphoma; psoriasis; and renal cell carcinoma. Orthologous to human PSMB9 (proteasome subunit beta 9); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

large multifunctional protease 2; Lmp2; low molecular mass polypeptide 2; low molecular mass protein 2; macropain chain 7; multicatalytic endopeptidase complex chain 7; proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2); proteasome (prosome, macropain) subunit, beta type, 9; proteasome chain 7; proteasome subunit beta type-9; proteasome subunit beta-1i; proteosome (prosome macropain) subunit beta type 9 (large multifunctional protease 2); proteosome (prosome, macropain) subunit, beta type 9; really interesting new gene 12 protein; RING12 protein

Orthologs:

Homo sapiens (human) : PSMB9 (proteasome subunit beta 9) HGNC Alliance
Mus musculus (house mouse) : Psmb9 (proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psmb9 (proteasome subunit beta 9)
Pan paniscus (bonobo/pygmy chimpanzee) : PSMB9 (proteasome subunit beta 9)
Canis lupus familiaris (dog) : PSMB9 (proteasome subunit beta 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psmb9 (proteasome subunit beta 9)
Sus scrofa (pig) : PSMB9 (proteasome subunit beta 9)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PSMB9 (proteasome subunit beta 9)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Psmb9 (proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2))	HGNC	Treefam, NCBI, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Psmb9 (proteasome subunit beta 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PSMB9 (proteasome subunit beta 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PSMB9 (proteasome subunit beta 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Psmb9 (proteasome subunit beta 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PSMB9 (proteasome subunit beta 9)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Psmb9 (proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2))	Alliance	DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):	PSMB9 (proteasome subunit beta 9)	Alliance	DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):	psmb9a (proteasome subunit beta 9a)	Alliance	DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):	psmb9b (proteasome subunit beta 9b)	Alliance	DIOPT (Hieranoid, OrthoFinder, PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):	PRE3	Alliance	DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):	Prosbeta1	Alliance	DIOPT (Ensembl Compara, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Caenorhabditis elegans (roundworm):	pbs-1	Alliance	DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	20	3,973,424 - 3,978,845 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	20	6,052,972 - 6,058,393 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	20	4,801,187 - 4,806,608 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	20	4,801,449 - 4,806,835 (+)	NCBI
Celera	20	6,268,113 - 6,273,528 (+)	NCBI		Celera
Cytogenetic Map	20	p12	NCBI
RH 3.4 Map	20	58.54	RGD

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Strain Sequence Variants (Rnor 5.0)

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Additional Information

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Nomenclature History

RGD Curation Notes

More on Psmb9
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

RGD Object Information
RGD ID:	3427
Created:	2000-05-25
Species:	Rattus norvegicus
Last Modified:	2019-04-23
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

Functional Annotation unavailable	Annotation Distribution unavailable	Genomic Variants unavailble for Mouse Genomic Variants unavailable
Functional Annotation	Annotation Distribution	Genomic Variants

Protein-Protein Interactions unavailable	Genome Viewer unavailable	Damaging Variants unavailble for Mouse Damaging Variants unavailable
Protein-Protein Interactions	Genome Viewer	Damaging Variants

Annotation Comparison unavailable	OLGA unavailable
Annotation Comparison	OLGA	Excel (Download)

Gene Enrichment unavailable
Gene Enrichment

RGD Manual Annotations

Imported Annotations - ClinVar

Imported Annotations - CTD

Imported Annotations - OMIM

Imported Annotations - KEGG (archival)