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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:terpenoid indole alkaloid
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Accession:CHEBI:65321 term browser browse the term
Definition:An indole alkaloid which is biosynthesised from L-tryptophan and isoprenoid building blocks.
Synonyms:related_synonym: terpenoid indole alkaloids


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ajmalicine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression
multiple interactions		 ISO raubasine results in increased expression of CASP3 protein
CASP3 protein affects the reaction [raubasine results in increased secretion of IL1B protein]; CASP3 protein affects the reaction [raubasine results in increased secretion of IL6 protein]; CASP3 protein affects the reaction [raubasine results in increased secretion of TNF protein]		 CTD PMID:38064316 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity
multiple interactions		 ISO raubasine results in decreased activity of CYP2D6 protein
raubasine inhibits the reaction [CYP2D6 protein affects the metabolism of Dextromethorphan]		 CTD PMID:15930738 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO raubasine inhibits the reaction [Calcitriol results in increased expression of CYP3A4 protein] CTD PMID:29782822 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Gsdme gasdermin E increases cleavage ISO raubasine results in increased cleavage of GSDME protein CTD PMID:38064316 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806 		JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion
multiple interactions		 ISO raubasine results in increased expression of IL1B protein
raubasine results in increased secretion of IL1B protein
[Acetylcysteine co-treated with raubasine] results in increased secretion of IL1B protein; CASP3 protein affects the reaction [raubasine results in increased secretion of IL1B protein]		 CTD PMID:38064316 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression
increases secretion
multiple interactions		 ISO raubasine results in increased expression of IL6 protein
raubasine results in increased secretion of IL6 protein
[Acetylcysteine co-treated with raubasine] results in increased secretion of IL6 protein; CASP3 protein affects the reaction [raubasine results in increased secretion of IL6 protein]		 CTD PMID:38064316 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
increases expression		 ISO raubasine results in increased secretion of TNF protein
[Acetylcysteine co-treated with raubasine] results in increased secretion of TNF protein; CASP3 protein affects the reaction [raubasine results in increased secretion of TNF protein]
raubasine results in increased expression of TNF protein		 CTD PMID:38064316 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
ajmaline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO Ajmaline inhibits the reaction [Calcitriol results in increased expression of CYP3A4 protein] CTD PMID:29782822 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Ajmaline results in decreased activity of KCNH2 protein CTD PMID:15599706 PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 decreases activity
affects response to substance		 ISO Ajmaline results in decreased activity of SCN5A protein
SCN5A protein affects the susceptibility to Ajmaline		 CTD PMID:10662748 PMID:15520322 PMID:20174578 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
alpha-ergocryptine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO ergocryptine results in increased activity of CASP3 protein CTD PMID:21295106 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
brucine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein multiple interactions EXP brucine inhibits the reaction [Diethylnitrosamine results in increased expression of AFP protein] CTD PMID:24060683 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO brucine results in increased expression of BAX protein CTD PMID:16443926 PMID:21684292 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO brucine results in decreased expression of BCL2 protein CTD PMID:16443926 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity
increases expression
multiple interactions		 ISO [brucine results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein; brucine results in increased activity of CASP3 protein
brucine results in increased expression of CASP3 protein
brucine results in increased expression of and results in increased activity of CASP3 protein; Cyclosporine inhibits the reaction [[brucine results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein]		 CTD PMID:16442763 PMID:16443926 PMID:17449162 PMID:21684292 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity		 ISO brucine results in increased activity of and results in increased cleavage of CASP9 protein; Cyclosporine inhibits the reaction [[brucine results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein]; Cyclosporine inhibits the reaction [brucine results in increased activity of and results in increased cleavage of CASP9 protein]
[brucine results in increased activity of CASP9 protein] which results in increased activity of CASP3 protein; brucine results in increased activity of CASP9 protein		 CTD PMID:16443926 PMID:21684292 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions EXP brucine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of CAT protein]; brucine inhibits the reaction [Diethylnitrosamine results in decreased activity of CAT protein] CTD PMID:24060683 PMID:30027798 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 multiple interactions ISO brucine affects the reaction [muscarinic toxin 7 binds to CHRM1 protein]; brucine affects the reaction [Pirenzepine analog binds to CHRM1 protein]; brucine analog affects the reaction [Acetylcholine binds to CHRM1 protein]; brucine analog affects the reaction [N-Methylscopolamine binds to CHRM1 protein]; brucine promotes the reaction [(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride binds to CHRM1 protein]; brucine promotes the reaction [5-methylfurtrethonium binds to CHRM1 protein]; brucine promotes the reaction [Acetylcholine binds to CHRM1 protein]; brucine promotes the reaction [Acetylcholine results in increased activity of CHRM1 protein]; brucine promotes the reaction [Bethanechol binds to CHRM1 protein]; brucine promotes the reaction [Carbachol binds to CHRM1 protein]; brucine promotes the reaction [furtrethonium binds to CHRM1 protein]; brucine promotes the reaction [oxotremorine M binds to CHRM1 protein]; brucine promotes the reaction [Pilocarpine binds to CHRM1 protein]; Quinuclidinyl Benzilate inhibits the reaction [brucine promotes the reaction [Acetylcholine results in increased activity of CHRM1 protein]] CTD PMID:9224827 PMID:9495826 PMID:10069518 PMID:10101037 PMID:15294002 More... NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions
affects binding		 ISO brucine analog affects the reaction [Acetylcholine binds to CHRM2 protein]; brucine analog affects the reaction [N-Methylscopolamine binds to CHRM2 protein]; brucine promotes the reaction [N-Methylscopolamine binds to CHRM2 protein]
brucine binds to CHRM2 protein		 CTD PMID:9495826 PMID:10069518 PMID:15647330 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 multiple interactions
affects binding		 ISO brucine analog affects the reaction [Acetylcholine binds to CHRM3 protein]; brucine analog affects the reaction [N-Methylscopolamine binds to CHRM3 protein]; brucine binds to and results in increased activity of CHRM3 protein mutant form; brucine promotes the reaction [(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride binds to CHRM3 protein]; brucine promotes the reaction [5-methylfurtrethonium binds to CHRM3 protein]; brucine promotes the reaction [Acetylcholine binds to CHRM3 protein]; brucine promotes the reaction [Arecoline binds to CHRM3 protein]; brucine promotes the reaction [Bethanechol binds to CHRM3 protein]; brucine promotes the reaction [Carbachol binds to CHRM3 protein]; brucine promotes the reaction [Carbachol results in increased activity of CHRM3 protein mutant form]; brucine promotes the reaction [furtrethonium binds to CHRM3 protein]; brucine promotes the reaction [oxotremorine M binds to CHRM3 protein]; brucine promotes the reaction [Pilocarpine binds to CHRM3 protein]
brucine binds to CHRM3 protein		 CTD PMID:9224827 PMID:10069518 PMID:15647330 PMID:20466821 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions
affects binding		 ISO brucine analog affects the reaction [Acetylcholine binds to CHRM4 protein]; brucine analog affects the reaction [N-Methylscopolamine binds to CHRM4 protein]; brucine promotes the reaction [(4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride binds to CHRM4 protein]; brucine promotes the reaction [5-methylfurtrethonium binds to CHRM4 protein]; brucine promotes the reaction [Bethanechol binds to CHRM4 protein]; brucine promotes the reaction [Carbachol binds to CHRM4 protein]; brucine promotes the reaction [furtrethonium binds to CHRM4 protein]; brucine promotes the reaction [oxotremorine M binds to CHRM4 protein]; brucine promotes the reaction [Pilocarpine binds to CHRM4 protein]; WIN 62577 inhibits the reaction [brucine binds to CHRM4 protein] CTD PMID:9224827 PMID:10069518 PMID:16709648 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Ctsd cathepsin D decreases expression ISO brucine results in decreased expression of CTSD mRNA
brucine results in decreased expression of CTSD mRNA; brucine results in decreased expression of CTSD protein		 CTD PMID:23933019 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP1A2 protein CTD PMID:21800547 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP brucine results in increased expression of CYP2B1 protein CTD PMID:7906730 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP brucine results in increased expression of CYP2B2 protein CTD PMID:7906730 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression EXP brucine results in increased expression of CYP2B3 protein CTD PMID:8850324 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases activity		 EXP [brucine co-treated with Glycyrrhetinic Acid] results in decreased activity of CYP2E1 protein; [brucine co-treated with liquiritin] results in decreased activity of CYP2E1 protein
brucine results in increased activity of CYP2E1 protein		 CTD PMID:21800547 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Fn1 fibronectin 1 decreases expression ISO brucine results in decreased expression of FN1 mRNA
brucine results in decreased expression of FN1 mRNA; brucine results in decreased expression of FN1 protein		 CTD PMID:23933019 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions ISO brucine analog binds to and results in decreased activity of GLRA1 protein; brucine binds to and results in decreased activity of GLRA1 protein CTD PMID:15081878 PMID:16687139 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression ISO brucine results in increased expression of GPT protein CTD PMID:31284022 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions EXP brucine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GPX1 protein] CTD PMID:30027798 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP brucine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSR protein] CTD PMID:30027798 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP brucine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of GSTA1 protein] CTD PMID:30027798 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Lox lysyl oxidase decreases expression ISO brucine results in decreased expression of LOX mRNA
brucine results in decreased expression of LOX mRNA; brucine results in decreased expression of LOX protein		 CTD PMID:23933019 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Mbp myelin basic protein affects expression EXP brucine affects the expression of MBP mRNA CTD PMID:22954530 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO brucine results in decreased expression of MMP2 mRNA
brucine results in decreased expression of MMP2 mRNA; brucine results in decreased expression of MMP2 protein		 CTD PMID:23933019 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Npas2 neuronal PAS domain protein 2 multiple interactions ISO NPAS2 protein affects the metabolism of and affects the susceptibility to brucine CTD PMID:31284022 NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP brucine inhibits the reaction [Diethylnitrosamine results in increased expression of PCNA protein] CTD PMID:24060683 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO brucine results in decreased expression of PTGS2 protein CTD PMID:16442763 PMID:17449162 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP brucine inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in decreased activity of SOD1 protein] CTD PMID:30027798 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Tnf tumor necrosis factor decreases secretion ISO brucine results in decreased secretion of TNF protein CTD PMID:21684292 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
caracurine VII term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrm2 cholinergic receptor, muscarinic 2 affects binding ISO caracurine binds to CHRM2 protein CTD PMID:15647330 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 affects binding ISO caracurine binds to CHRM3 protein CTD PMID:15647330 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
dihydroergotamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Dihydroergotamine results in decreased activity of ABCB11 protein CTD PMID:28437613 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Dihydroergotamine results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
increases activity		 ISO
EXP		 Dihydroergotamine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Dihydroergotamine results in decreased activity of CYP1A1 protein
Dihydroergotamine results in increased activity of CYP1A1 protein		 CTD PMID:18420780 PMID:18493746 PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Dihydroergotamine results in decreased activity of CYP1B1 protein CTD PMID:18420780 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases activity ISO Dihydroergotamine results in decreased activity of CYP2A4 protein CTD PMID:18420780 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity ISO Dihydroergotamine results in decreased activity of CYP2B10 protein CTD PMID:18420780 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO Dihydroergotamine results in decreased activity of CYP2C29 protein CTD PMID:18420780 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Dihydroergotamine results in decreased activity of CYP2D6 protein
Dihydroergotamine results in decreased activity of CYP2D22 protein		 CTD PMID:18420780 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Dihydroergotamine results in decreased activity of CYP3A4 protein CTD PMID:18420780 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B multiple interactions EXP dihydroergotamine binds to protein 5-Htr5b; inhibits the reaction[5-carboxamidotryptamine binds to 5-Htr5b] RGD PMID:8224165 RGD:2303647 NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835 		JBrowse link
G Il24 interleukin 24 increases expression ISO Dihydroergotamine results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Dihydroergotamine results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
ergocristine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity		 ISO ergocristine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
ergocristine results in decreased activity of ABCB11 protein		 CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Casp3 caspase 3 increases activity ISO ergocristine results in increased activity of CASP3 protein CTD PMID:21295106 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
ergosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO ergosine results in increased activity of CASP3 protein CTD PMID:21295106 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
ergotamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Ergotamine inhibits the reaction [Nitroglycerin results in increased expression of CALCA protein] CTD PMID:19121572 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Casp3 caspase 3 increases activity ISO Ergotamine results in increased activity of CASP3 protein CTD PMID:21295106 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Ergotamine inhibits the reaction [Nitroglycerin results in increased expression of FOS protein] CTD PMID:19121572 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Ergotamine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions ISO Ergotamine binds to and results in increased activity of HTR2B protein CTD PMID:11104741 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
fumigaclavine C term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma decreases expression ISO fumigaclavine C results in decreased expression of IFNG mRNA; fumigaclavine C results in decreased expression of IFNG protein CTD PMID:16023606 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il12a interleukin 12A decreases expression ISO fumigaclavine C results in decreased expression of IL12A mRNA CTD PMID:16023606 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO fumigaclavine C results in decreased expression of IL1B mRNA CTD PMID:16023606 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 decreases expression ISO fumigaclavine C results in decreased expression of IL2 mRNA; fumigaclavine C results in decreased expression of IL2 protein CTD PMID:16023606 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
decreases expression		 ISO fumigaclavine C results in decreased activity of MMP9 protein
fumigaclavine C results in decreased expression of MMP9 mRNA		 CTD PMID:16023606 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Tnf tumor necrosis factor decreases expression ISO fumigaclavine C results in decreased expression of TNF mRNA CTD PMID:16023606 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
ibogaine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Ibogaine results in decreased activity of KCNH2 protein CTD PMID:23707769 PMID:24307198 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 decreases activity ISO Ibogaine results in decreased activity of SCN5A protein CTD PMID:23707769 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Sec24d SEC24 homolog D, COPII coat complex component increases response to substance ISO SEC24D protein results in increased susceptibility to Ibogaine CTD PMID:27555326 NCBI chr 2:211,418,557...211,526,588
Ensembl chr 2:211,418,623...211,526,587 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
increases expression		 ISO Ibogaine inhibits the reaction [SLC6A3 protein mutant form results in decreased import of Dopamine]; Ibogaine promotes the reaction [SLC6A3 protein results in increased import of Dopamine]
Ibogaine results in increased expression of SLC6A3 protein		 CTD PMID:27555326 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
icajine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scn5a sodium voltage-gated channel alpha subunit 5 multiple interactions ISO icajine binds to and results in decreased activity of SCN5A protein CTD PMID:21616062 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
mesulergine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr2b 5-hydroxytryptamine receptor 2B affects binding
multiple interactions		 ISO mesulergine binds to HTR2B protein
Fluoxetine promotes the reaction [mesulergine binds to HTR2B protein]		 CTD PMID:11930908 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects binding
multiple interactions		 ISO
EXP		 mesulergine binds to HTR2C protein
N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [mesulergine binds to HTR2C protein]
Carbamazepine inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]]; Carbamazepine inhibits the reaction [Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]]; Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]; Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]; Plant Extracts inhibits the reaction [Pilocarpine affects the reaction [mesulergine binds to HTR2C protein]]; Plant Extracts inhibits the reaction [Pilocarpine inhibits the reaction [mesulergine binds to HTR2C protein]]		 CTD PMID:18083778 PMID:19439326 PMID:19700373 PMID:29458138 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 affects binding
multiple interactions		 ISO mesulergine binds to HTR7 protein
[mesulergine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; mesulergine inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]		 CTD PMID:14578406 PMID:20827463 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Prl prolactin multiple interactions EXP mesulergine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:1421203 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
methysergide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Methysergide results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions EXP Methysergide promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA1A protein] CTD PMID:16545797 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Calca calcitonin-related polypeptide alpha affects activity EXP Methysergide affects the activity of CALCA protein CTD PMID:10075105 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B affects binding EXP Methysergide binds to HTR1B protein CTD PMID:11888550 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B multiple interactions EXP methysergide binds to protein 5-Htr5b; inhibits the reaction[5-carboxamidotryptamine binds to 5-Htr5b] RGD PMID:8224165 RGD:2303647 NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835 		JBrowse link
Mitragynine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects activity ISO mitragynine affects the activity of ABCG2 protein CTD PMID:30083819 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis
decreases activity
multiple interactions		 ISO CES1 protein results in increased hydrolysis of mitragynine
mitragynine results in decreased activity of CES1 protein
[mitragynine results in decreased activity of CES1 protein] which results in decreased metabolism of Oseltamivir		 CTD PMID:25445008 PMID:37716419 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression		 ISO mitragynine results in increased activity of CYP1A2 protein
mitragynine results in increased expression of CYP1A2 mRNA; mitragynine results in increased expression of CYP1A2 protein		 CTD PMID:23274770 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO mitragynine results in decreased activity of CYP2C19 protein CTD PMID:31707106 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases expression
decreases activity		 ISO mitragynine results in increased expression of CYP2D6 protein
mitragynine results in decreased activity of CYP2D6 protein		 CTD PMID:23274770 PMID:31707106 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases activity
increases expression		 ISO mitragynine results in increased activity of CYP3A4 protein
mitragynine results in increased expression of CYP3A4 mRNA; mitragynine results in increased expression of CYP3A4 protein		 CTD PMID:23274770 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases expression
multiple interactions		 ISO mitragynine results in decreased expression of KCNH2 protein
mitragynine binds to and results in decreased activity of KCNH2 protein		 CTD PMID:27260674 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Oprd1 opioid receptor, delta 1 affects binding ISO mitragynine binds to OPRD1 protein CTD PMID:27192616 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oprk1 opioid receptor, kappa 1 affects binding
multiple interactions		 ISO mitragynine binds to OPRK1 protein
mitragynine inhibits the reaction [3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer binds to and results in increased activity of OPRK1 protein]		 CTD PMID:27192616 NCBI chr 5:13,860,016...13,877,823
Ensembl chr 5:13,860,021...13,877,823 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions
increases activity
affects binding		 ISO mitragynine affects the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]; mitragynine binds to and results in increased activity of OPRM1 protein; mitragynine inhibits the reaction [Tretinoin results in increased expression of OPRM1 mRNA]
mitragynine results in increased activity of OPRM1 protein
mitragynine inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]
mitragynine binds to OPRM1 protein		 CTD PMID:23608241 PMID:27192616 PMID:32734307 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO mitragynine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of PTGS1 protein] CTD PMID:21513785 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO mitragynine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; mitragynine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein] CTD PMID:21513785 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
paxilline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO paxilline inhibits the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]] CTD PMID:12807996 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO paxilline inhibits the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]] CTD PMID:12807996 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Fasn fatty acid synthase multiple interactions
increases expression		 ISO [Bexarotene co-treated with paxilline] results in increased expression of FASN mRNA; [CD 3254 co-treated with paxilline] results in increased expression of FASN mRNA
paxilline results in increased expression of FASN mRNA		 CTD PMID:32123961 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 multiple interactions ISO paxilline inhibits the reaction [NS 1619 inhibits the reaction [Oxygen deficiency results in increased expression of FLT1 protein]] CTD PMID:25371888 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 affects response to substance EXP KCNMA1 protein affects the susceptibility to paxilline CTD PMID:22226998 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Mlxipl MLX interacting protein-like increases expression ISO paxilline results in increased expression of MLXIPL mRNA CTD PMID:32123961 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions
increases expression		 ISO [Bexarotene co-treated with paxilline] results in increased expression of NR0B2 mRNA; [CD 3254 co-treated with paxilline] results in increased expression of NR0B2 mRNA
paxilline results in increased expression of NR0B2 mRNA		 CTD PMID:32123961 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions
increases expression		 ISO [Bexarotene co-treated with paxilline] results in increased expression of NR1H3 mRNA; [CD 3254 co-treated with paxilline] results in increased expression of NR1H3 mRNA; NR1H3 protein promotes the reaction [paxilline results in increased abundance of Lipids]
paxilline results in increased expression of NR1H3 mRNA		 CTD PMID:20079722 PMID:32123961 NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722 		JBrowse link
G Nrip1 nuclear receptor interacting protein 1 multiple interactions
increases expression		 ISO [CD 3254 co-treated with paxilline] results in increased expression of NRIP1 mRNA
paxilline results in increased expression of NRIP1 mRNA		 CTD PMID:32123961 NCBI chr11:14,895,843...14,979,490
Ensembl chr11:14,895,553...14,981,761 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO paxilline inhibits the reaction [cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein]] CTD PMID:12807996 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
increases expression		 ISO [CD 3254 co-treated with paxilline] results in increased expression of SCD mRNA
paxilline results in increased expression of SCD mRNA		 CTD PMID:32123961 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression		 ISO [Bexarotene co-treated with paxilline] results in increased expression of SREBF1 mRNA; [CD 3254 co-treated with paxilline] results in increased expression of SREBF1 mRNA
paxilline results in increased expression of SREBF1 mRNA		 CTD PMID:32123961 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO paxilline inhibits the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of AKT1 protein]]; paxilline inhibits the reaction [cilostazol inhibits the reaction [TNF results in decreased phosphorylation of CREB1 protein]]; paxilline inhibits the reaction [cilostazol inhibits the reaction [TNF results in increased phosphorylation of PTEN protein]] CTD PMID:12807996 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
rescinnamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO rescinnamine results in increased expression of ABCB1 mRNA CTD PMID:7476894 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO rescinnamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
reserpic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO reserpic acid inhibits the reaction [Calcitriol results in increased expression of CYP3A4 protein] CTD PMID:29782822 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
reserpine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity		 ISO Reserpine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Reserpine results in decreased activity of ABCB11 protein		 CTD PMID:20829430 PMID:23956101 PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
decreases activity		 ISO Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]; Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]
Reserpine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
Reserpine results in increased expression of ABCB1 mRNA; Reserpine results in increased expression of ABCB1 protein
Reserpine results in decreased activity of ABCB1 protein		 CTD PMID:7476894 PMID:8632764 PMID:10617675 PMID:12235267 PMID:19528478 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Reserpine inhibits the reaction [ABCG2 protein results in increased transport of Irinotecan] CTD PMID:12869632 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Ache acetylcholinesterase multiple interactions
affects activity		 EXP [Plant Extracts results in increased abundance of Dronabinol] inhibits the reaction [Reserpine affects the activity of ACHE protein] CTD PMID:28212939 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Adra1d adrenoceptor alpha 1D increases response to substance
increases expression		 EXP ADRA1D protein results in increased susceptibility to Reserpine
Reserpine results in increased expression of ADRA1D mRNA		 CTD PMID:15159276 PMID:17676312 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354 		JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression EXP Reserpine results in increased expression of ADRA2A mRNA CTD PMID:11264240 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adrb1 adrenoceptor beta 1 increases expression
increases stability		 EXP Reserpine results in increased expression of ADRB1 mRNA; Reserpine results in increased expression of ADRB1 protein
Reserpine results in increased stability of ADRB1 mRNA		 CTD PMID:1336118 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression EXP Reserpine results in increased expression of ADRB2 mRNA CTD PMID:1664493 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 increases expression EXP Reserpine results in increased expression of AGTR2 mRNA; Reserpine results in increased expression of AGTR2 protein CTD PMID:20964730 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Reserpine results in increased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions		 ISO Reserpine results in decreased phosphorylation of AKT1 protein
arsenic trioxide promotes the reaction [Reserpine results in decreased phosphorylation of AKT1 protein]		 CTD PMID:26114099 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 multiple interactions ISO Reserpine inhibits the reaction [Folic Acid results in increased activity of AMD1 protein] CTD PMID:17371283 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476 		JBrowse link
G Ar androgen receptor multiple interactions ISO Reserpine inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein] CTD PMID:29162470 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein multiple interactions EXP Reserpine inhibits the reaction [Cocaine results in increased expression of ARC mRNA] CTD PMID:7722525 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 EXP IAPP protein inhibits the reaction [Reserpine results in increased expression of BAX protein] CTD PMID:19463876 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 EXP IAPP protein inhibits the reaction [Reserpine results in decreased expression of BCL2 protein] CTD PMID:19463876 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions		 ISO
EXP		 Reserpine results in decreased expression of BDNF protein
cerebrolysin inhibits the reaction [Reserpine results in decreased expression of BDNF protein]; Fluoxetine inhibits the reaction [Reserpine results in decreased expression of BDNF protein]
arsenic trioxide promotes the reaction [Reserpine results in decreased expression of BDNF protein]		 CTD PMID:26114099 PMID:33279466 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects binding ISO Reserpine binds to BIRC5 promoter CTD PMID:17968851 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G C3 complement C3 affects expression EXP Reserpine affects the expression of C3 mRNA CTD PMID:18363858 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 EXP IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP3 protein] CTD PMID:19463876 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity		 EXP IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP8 protein] CTD PMID:19463876 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase multiple interactions
decreases expression
increases expression		 EXP Plant Extracts inhibits the reaction [Reserpine results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Reserpine results in decreased expression of CAT protein]
Reserpine results in increased expression of CAT protein		 CTD PMID:14685008 PMID:16444668 PMID:19109989 PMID:19761039 PMID:20628966 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Reserpine results in decreased expression of CCND1 mRNA; Reserpine results in decreased expression of CCND1 protein CTD PMID:19607803 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of CDKN1B protein CTD PMID:11318962 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein]; [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA] CTD PMID:18504326 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Chga chromogranin A multiple interactions
increases expression
increases activity		 ISO
EXP		 CHGA protein alternative form inhibits the reaction [Reserpine results in increased activity of CHGA promoter]; Chlorisondamine inhibits the reaction [Reserpine results in increased activity of CHGA promoter]
Reserpine results in increased expression of CHGA mRNA		 CTD PMID:1907749 PMID:8189248 PMID:12799369 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chgb chromogranin B increases expression EXP Reserpine results in increased expression of CHGB mRNA; Reserpine results in increased expression of CHGB protein CTD PMID:1907749 PMID:8189248 PMID:8361347 NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 increases expression
decreases expression		 EXP Reserpine results in increased expression of CHRM1 mRNA
Reserpine results in decreased expression of CHRM1 protein		 CTD PMID:1506860 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Reserpine results in decreased expression of CNR1 mRNA CTD PMID:11358453 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cpe carboxypeptidase E increases expression EXP Reserpine results in increased expression of CPE mRNA CTD PMID:8189248 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Crem cAMP responsive element modulator multiple interactions
increases expression		 EXP Reserpine promotes the reaction [CREM protein binds to TH promoter]
Reserpine results in increased expression of CREM mRNA alternative form; Reserpine results in increased expression of CREM protein; Reserpine results in increased expression of CREM protein alternative form		 CTD PMID:8810303 PMID:11438978 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Crh corticotropin releasing hormone increases expression EXP Reserpine results in increased expression of CRH mRNA; Reserpine results in increased expression of CRH protein CTD PMID:1850078 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Reserpine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A1 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] CTD PMID:15627480 PMID:18493746 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; [Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:16510159 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Reserpine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions		 ISO Reserpine results in increased expression of CYP3A4 mRNA; Reserpine results in increased expression of CYP3A4 protein
[Reserpine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Reserpine inhibits the reaction [Calcitriol results in increased expression of CYP3A4 protein]		 CTD PMID:8632764 PMID:16837568 PMID:17041008 PMID:29782822 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO Reserpine results in increased expression of CYP3A5 protein CTD PMID:8632764 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyss cystatin S multiple interactions EXP Reserpine inhibits the reaction [Isoproterenol results in increased expression of CYSS mRNA] CTD PMID:9447264 NCBI chr 3:137,432,049...137,436,654
Ensembl chr 3:137,432,049...137,436,610 		JBrowse link
G Dbh dopamine beta-hydroxylase decreases activity
increases expression
increases stability
increases activity		 EXP Reserpine results in decreased activity of DBH protein
Reserpine results in increased expression of DBH mRNA
Reserpine results in increased stability of DBH protein
Reserpine results in increased activity of DBH protein		 CTD PMID:1359376 PMID:2325165 PMID:7984052 PMID:8189248 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Ddc dopa decarboxylase increases expression EXP Reserpine results in increased expression of DDC mRNA CTD PMID:1359376 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Drd1 dopamine receptor D1 increases expression EXP Reserpine results in increased expression of DRD1 mRNA CTD PMID:8419537 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
increases expression		 ISO
EXP		 DRD2 protein affects the susceptibility to [8-(3-chlorostyryl)caffeine co-treated with Reserpine]
Reserpine results in increased expression of DRD2 mRNA; Reserpine results in increased expression of DRD2 mRNA alternative form		 CTD PMID:1331675 PMID:8419537 PMID:11172060 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression		 EXP [Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA; eticlopride inhibits the reaction [[Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA]; Quinpirole inhibits the reaction [Reserpine results in increased expression of EGR1 mRNA]; Reserpine promotes the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [[Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]]
Reserpine results in increased expression of EGR1 mRNA; Reserpine results in increased expression of EGR1 protein		 CTD PMID:1347779 PMID:8063705 PMID:9729266 PMID:9890435 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases response to substance EXP ERBB2 protein results in increased susceptibility to Reserpine CTD PMID:8093862 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Fabp7 fatty acid binding protein 7 affects expression EXP Reserpine affects the expression of FABP7 mRNA CTD PMID:18363858 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
increases phosphorylation		 EXP 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine promotes the reaction [Reserpine results in increased expression of FOS protein]; 3,7-dimethyl-1-propargylxanthine inhibits the reaction [Reserpine results in increased expression of FOS protein]; 8-(3-chlorostyryl)caffeine promotes the reaction [Quinpirole inhibits the reaction [Reserpine results in increased expression of FOS protein]]; Quinpirole inhibits the reaction [Reserpine results in increased expression of FOS protein]; Quinpirole promotes the reaction [Reserpine results in increased expression of FOS protein]; Reserpine inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Quinpirole] results in increased expression of FOS protein]; Reserpine inhibits the reaction [Cocaine results in increased expression of FOS protein]; Reserpine promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased expression of FOS protein]; Reserpine promotes the reaction [Amphetamine results in increased expression of FOS protein]; Reserpine promotes the reaction [Quinpirole results in increased expression of FOS protein]; Theophylline inhibits the reaction [Reserpine results in increased expression of FOS protein]
Reserpine results in increased expression of FOS mRNA; Reserpine results in increased expression of FOS protein
Reserpine results in increased phosphorylation of FOS protein		 CTD PMID:1359376 PMID:1686849 PMID:2118661 PMID:7845612 PMID:7914358 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression
multiple interactions		 EXP Reserpine results in increased expression of GAD1 mRNA
Clenbuterol inhibits the reaction [Reserpine results in increased expression of GAD1 mRNA]		 CTD PMID:8774452 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression
increases expression
multiple interactions		 EXP Reserpine results in decreased expression of GAL mRNA
Reserpine results in increased expression of GAL mRNA
Desipramine inhibits the reaction [Reserpine results in increased expression of GAL mRNA]		 CTD PMID:1279347 PMID:1698642 PMID:1705056 PMID:1717808 PMID:9512271 More... NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Gast gastrin multiple interactions EXP Reserpine inhibits the reaction [Levodopa results in decreased cleavage of GAST protein] CTD PMID:10332097 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP Reserpine results in increased expression of GCH1 mRNA; Reserpine results in increased expression of GCH1 mRNA alternative form CTD PMID:8103077 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Reserpine results in increased expression of GCNT3 mRNA CTD PMID:26198647 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562 		JBrowse link
G Gnai1 G protein subunit alpha i1 increases expression EXP Reserpine results in increased expression of GNAI1 protein CTD PMID:11264240 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 increases expression EXP Reserpine results in increased expression of GNAI2 mRNA; Reserpine results in increased expression of GNAI2 protein CTD PMID:8419537 PMID:11264240 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 increases expression EXP Reserpine results in increased expression of GNAI3 protein CTD PMID:11264240 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gnao1 G protein subunit alpha o1 increases expression EXP Reserpine results in increased expression of GNAO1 mRNA; Reserpine results in increased expression of GNAO1 protein CTD PMID:8419537 PMID:11264240 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnas GNAS complex locus increases expression
decreases expression		 EXP Reserpine results in increased expression of GNAS mRNA; Reserpine results in increased expression of GNAS protein
Reserpine results in decreased expression of GNAS protein alternative form		 CTD PMID:1336118 PMID:8419537 PMID:11264240 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 decreases expression
increases expression		 EXP Reserpine results in decreased expression of GRM5 mRNA
Reserpine results in increased expression of GRM5 protein		 CTD PMID:16890937 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Hgf hepatocyte growth factor increases expression EXP Reserpine results in increased expression of HGF protein CTD PMID:16081063 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 multiple interactions ISO HSPG2 gene results in increased susceptibility to [Haloperidol co-treated with Reserpine] CTD PMID:20072119 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A decreases expression ISO Reserpine results in decreased expression of HTR1A protein CTD PMID:26114099 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Iapp islet amyloid polypeptide multiple interactions EXP IAPP protein inhibits the reaction [Reserpine results in decreased expression of BCL2 protein]; IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP3 protein]; IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP8 protein]; IAPP protein inhibits the reaction [Reserpine results in increased expression of BAX protein]; IAPP protein inhibits the reaction [Reserpine results in increased expression of TNFSF10 protein] CTD PMID:19463876 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions		 ISO Reserpine results in decreased expression of IL10 mRNA; Reserpine results in decreased expression of IL10 protein
SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 mRNA]; SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 protein]		 CTD PMID:16985181 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il18 interleukin 18 increases expression EXP Reserpine results in increased expression of IL18 mRNA CTD PMID:8999896 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Reserpine results in increased expression of JUN mRNA CTD PMID:1359376 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Reserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]] CTD PMID:1347779 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 decreases activity
multiple interactions		 ISO Reserpine results in decreased activity of KCNA3 protein
[Reserpine results in decreased activity of KCNA3 protein] which results in decreased import of Thallium		 CTD PMID:21362439 NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 increases expression EXP Reserpine results in increased expression of KCNA5 mRNA CTD PMID:12606256 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression EXP Reserpine results in decreased expression of KCND2 mRNA CTD PMID:12606256 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728 		JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 decreases expression EXP Reserpine results in decreased expression of KCND3 mRNA CTD PMID:12606256 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions		 ISO Reserpine results in decreased activity of KCNH2 protein
[Reserpine results in decreased activity of KCNH2 protein] which results in decreased import of Thallium		 CTD PMID:21362439 PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Lep leptin increases expression ISO Reserpine results in increased expression of LEP mRNA CTD PMID:10050748 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases response to substance
decreases expression		 ISO MYC protein results in increased susceptibility to Reserpine
Reserpine results in decreased expression of MYC protein		 CTD PMID:8093862 PMID:19607803 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression EXP Reserpine results in increased expression of NCF1 mRNA; Reserpine results in increased expression of NCF1 protein CTD PMID:20964730 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases activity ISO Reserpine results in decreased activity of NFE2L2 protein CTD PMID:30203046 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ngf nerve growth factor increases expression EXP Reserpine results in increased expression of NGF mRNA; Reserpine results in increased expression of NGF protein CTD PMID:1996081 PMID:8593794 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nos1 nitric oxide synthase 1 increases expression EXP Reserpine results in increased expression of NOS1 mRNA; Reserpine results in increased expression of NOS1 protein CTD PMID:7533141 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression
decreases expression		 EXP Chlorisondamine inhibits the reaction [Reserpine results in increased expression of NPY mRNA]; Chlorisondamine promotes the reaction [Reserpine results in increased expression of NPY mRNA]; Dexamethasone inhibits the reaction [Reserpine results in increased expression of NPY mRNA]
Reserpine results in increased expression of NPY mRNA; Reserpine results in increased expression of NPY protein
Reserpine results in decreased expression of NPY mRNA; Reserpine results in decreased expression of NPY protein		 CTD PMID:1671012 PMID:1676830 PMID:1687976 PMID:1698642 PMID:1713314 More... NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [Reserpine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:17041008 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
decreases activity		 ISO [Reserpine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA
Reserpine results in decreased activity of NR1I3 protein		 CTD PMID:17041008 PMID:30203046 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression EXP Reserpine results in increased expression of NR3C1 mRNA CTD PMID:7984052 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions
decreases expression		 ISO arsenic trioxide promotes the reaction [Reserpine results in decreased expression of NTRK2 protein] CTD PMID:26114099 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nts neurotensin increases expression EXP Reserpine results in increased expression of NTS mRNA CTD PMID:1850078 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression
multiple interactions		 EXP
ISO		 Reserpine results in decreased expression of ODC1 protein
Reserpine inhibits the reaction [CB 3717 results in increased activity of ODC1 protein]; Reserpine inhibits the reaction [CB 3717 results in increased expression of ODC1 mRNA]; Reserpine inhibits the reaction [Testosterone results in increased activity of ODC1 protein]; Reserpine inhibits the reaction [Testosterone results in increased expression of ODC1 mRNA]		 CTD PMID:6519379 PMID:9194572 PMID:10354516 PMID:17371283 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase increases expression EXP Reserpine results in increased expression of PAM mRNA CTD PMID:8189248 NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of PCNA protein CTD PMID:11318962 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 increases expression EXP Reserpine results in increased expression of PCSK2 mRNA CTD PMID:8189248 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Penk proenkephalin multiple interactions
increases expression
decreases expression		 EXP Apomorphine inhibits the reaction [Reserpine results in increased expression of PENK mRNA]
Reserpine results in increased expression of PENK mRNA; Reserpine results in increased expression of PENK protein
Reserpine results in decreased expression of PENK mRNA		 CTD PMID:1331675 PMID:1850078 PMID:3188958 PMID:3838946 PMID:4078631 More... NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase multiple interactions
increases expression
decreases expression		 EXP Chlorisondamine inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]; Dexamethasone inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]; POMC protein alternative form inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]; Reserpine results in increased expression of and results in increased activity of PNMT protein
Reserpine results in increased expression of PNMT mRNA		 CTD PMID:1359376 PMID:1687976 PMID:1714554 PMID:2903502 PMID:8063705 More... NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Pomc proopiomelanocortin increases expression
multiple interactions		 EXP Reserpine results in increased expression of POMC mRNA; Reserpine results in increased expression of POMC protein alternative form
POMC protein alternative form inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]		 CTD PMID:8479280 PMID:20504635 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha decreases expression ISO Reserpine results in decreased expression of PRKACA protein CTD PMID:26114099 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prl prolactin increases expression EXP Reserpine results in increased expression of PRL protein CTD PMID:11071396 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prss1 serine protease 1 decreases expression
increases expression		 EXP Reserpine results in decreased expression of PRSS1 protein
Reserpine results in increased expression of PRSS1 protein		 CTD PMID:8625754 NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Reserpine results in increased expression of PTGS2 protein CTD PMID:16081063 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase increases expression EXP Reserpine results in increased expression of PTS mRNA CTD PMID:7545485 NCBI chr 8:50,870,838...50,877,869
Ensembl chr 8:50,870,841...50,877,869 		JBrowse link
G Rasd2 RASD family, member 2 decreases expression EXP Reserpine results in decreased expression of RASD2 mRNA CTD PMID:16352400 NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 decreases expression EXP Reserpine results in decreased expression of RGS10 mRNA CTD PMID:14505795 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 decreases expression EXP Reserpine results in decreased expression of RGS2 mRNA CTD PMID:14505795 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression EXP Reserpine results in decreased expression of RGS4 mRNA CTD PMID:14505795 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs5 regulator of G-protein signaling 5 decreases expression EXP Reserpine results in decreased expression of RGS5 mRNA CTD PMID:14505795 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 decreases expression EXP Reserpine results in decreased expression of RGS8 mRNA CTD PMID:14505795 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance
decreases expression		 ISO
EXP		 RGS9 affects the susceptibility to Reserpine
Reserpine results in decreased expression of RGS9 mRNA		 CTD PMID:14505795 PMID:15728856 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
G Scg2 secretogranin II increases expression EXP Reserpine results in increased expression of SCG2 mRNA CTD PMID:1907749 PMID:8189248 PMID:8361347 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 mRNA; [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 protein CTD PMID:11318962 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 increases expression ISO Reserpine results in increased expression of SIAH1 mRNA CTD PMID:19607803 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808 		JBrowse link
G Slc18a1 solute carrier family 18 member A1 decreases activity
multiple interactions		 ISO Reserpine results in decreased activity of SLC18A1 protein
Reserpine inhibits the reaction [SLC18A1 protein results in increased uptake of Serotonin]		 CTD PMID:8245983 PMID:21712771 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 affects binding
multiple interactions
decreases activity
increases expression
affects response to substance
decreases response to substance		 ISO
EXP		 Reserpine binds to SLC18A2 protein
Reserpine inhibits the reaction [SLC18A2 protein results in increased uptake of Dopamine]
Reserpine results in decreased activity of SLC18A2 protein
SLC18A2 protein binds to Reserpine
Reserpine results in increased expression of SLC18A2 mRNA
SLC18A2 affects the susceptibility to Reserpine
Reserpine inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin]; Serotonin inhibits the reaction [SLC18A2 protein binds to Reserpine]
SLC18A2 gene SNP results in decreased susceptibility to Reserpine		 CTD PMID:1438304 PMID:7912402 PMID:8189248 PMID:9038139 PMID:15475732 More... NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 decreases expression EXP Reserpine results in decreased expression of SLC6A2 mRNA CTD PMID:7478180 PMID:7616203 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 decreases activity
affects response to substance		 ISO Reserpine results in decreased activity of SLC6A3 protein
SLC6A3 gene mutant form affects the susceptibility to Reserpine		 CTD PMID:17664021 PMID:19615345 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP Reserpine results in decreased expression of SLC6A4 mRNA CTD PMID:10027743 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Snca synuclein alpha affects response to substance
increases expression
multiple interactions		 ISO
EXP		 SNCA protein mutant form affects the susceptibility to Reserpine
Reserpine results in increased expression of SNCA protein
[Levodopa co-treated with Carbidopa] inhibits the reaction [Reserpine results in increased expression of SNCA protein]; Dextromethorphan promotes the reaction [zolmitriptan inhibits the reaction [Reserpine results in increased expression of SNCA protein]]; Glutamic Acid inhibits the reaction [zolmitriptan inhibits the reaction [Reserpine results in increased expression of SNCA protein]]; zolmitriptan inhibits the reaction [Reserpine results in increased expression of SNCA protein]		 CTD PMID:18622040 PMID:38229316 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Reserpine results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Syt7 synaptotagmin 7 multiple interactions EXP [Reserpine co-treated with Apomorphine] results in increased expression of SYT7 mRNA CTD PMID:17719177 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions
increases expression		 EXP [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine co-treated with Quinpirole] results in increased expression of TAC1 mRNA; [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine] results in increased expression of TAC1 mRNA; Apomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA] CTD PMID:9751140 PMID:17719177 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO Reserpine results in increased expression of TFF1 mRNA CTD PMID:35307500 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Th tyrosine hydroxylase increases expression
increases activity
decreases expression
affects activity
increases stability
multiple interactions		 ISO
EXP		 Reserpine results in increased expression of TH mRNA
Reserpine results in increased activity of TH protein
Reserpine results in increased expression of TH mRNA; Reserpine results in increased expression of TH protein
Reserpine results in decreased expression of TH mRNA
Reserpine affects the activity of TH protein
Reserpine results in increased stability of TH mRNA
Bicuculline promotes the reaction [Reserpine affects the activity of TH protein]; Bicuculline promotes the reaction [Reserpine results in increased expression of TH mRNA]; Chlorisondamine inhibits the reaction [Reserpine results in increased expression of TH mRNA]; Chlorisondamine promotes the reaction [Reserpine results in increased expression of TH mRNA]; Desipramine inhibits the reaction [Reserpine results in increased expression of TH mRNA]; Reserpine promotes the reaction [CREM protein binds to TH promoter]; Reserpine results in increased expression of and results in increased activity of TH protein		 CTD PMID:1350653 PMID:1359376 PMID:1676830 PMID:1687822 PMID:1687976 More... NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 EXP Reserpine results in increased expression of TNF protein
cerebrolysin inhibits the reaction [Reserpine results in increased expression of TNF protein]; Fluoxetine inhibits the reaction [Reserpine results in increased expression of TNF protein]		 CTD PMID:33279466 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions
increases expression		 EXP IAPP protein inhibits the reaction [Reserpine results in increased expression of TNFSF10 protein] CTD PMID:19463876 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tph1 tryptophan hydroxylase 1 increases activity
decreases activity		 EXP Reserpine results in increased activity of TPH1 protein
Reserpine results in decreased activity of TPH1 protein		 CTD PMID:8369965 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
G Vgf VGF nerve growth factor inducible increases expression EXP Reserpine results in increased expression of VGF mRNA CTD PMID:8189248 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341 		JBrowse link
G Vip vasoactive intestinal peptide increases expression EXP Reserpine results in increased expression of VIP mRNA CTD PMID:1850078 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
strychnine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases expression EXP Strychnine results in increased expression of CASP3 mRNA CTD PMID:19815060 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 affects binding
multiple interactions		 ISO Strychnine binds to CHRM2 protein
Strychnine promotes the reaction [N-Methylscopolamine binds to CHRM2 protein]		 CTD PMID:9495826 PMID:15647330 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 affects binding EXP
ISO		 Strychnine binds to CHRM3 protein CTD PMID:12435818 PMID:15647330 NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 multiple interactions ISO Strychnine promotes the reaction [N-Methylscopolamine binds to CHRM4 protein] CTD PMID:9495826 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions EXP Strychnine results in increased expression of and results in increased degradation of CYP2B1 protein CTD PMID:7906730 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression EXP Strychnine results in increased expression of CYP2B2 protein CTD PMID:7906730 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP [Strychnine co-treated with Ketoconazole] results in decreased expression of CYP3A23-3A1 protein; [Strychnine co-treated with Phenobarbital] results in increased expression of CYP3A23-3A1 mRNA CTD PMID:35358606 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP Strychnine results in increased expression of GFAP mRNA CTD PMID:22954530 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions
decreases activity		 ISO
EXP		 Strychnine analog binds to and results in decreased activity of GLRA1 protein; Strychnine binds to and results in decreased activity of GLRA1 protein; Strychnine promotes the reaction [Genistein results in decreased activity of GLRA1 protein]; Strychnine promotes the reaction [Quercetin results in decreased activity of GLRA1 protein]
Strychnine results in decreased activity of GLRA1 protein
Genistein promotes the reaction [Strychnine results in decreased activity of GLRA1 protein]; Quercetin promotes the reaction [Strychnine results in decreased activity of GLRA1 protein]		 CTD PMID:7752562 PMID:15081878 PMID:16687139 PMID:20719748 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162 		JBrowse link
G Glra2 glycine receptor, alpha 2 decreases activity EXP Strychnine results in decreased activity of GLRA2 protein CTD PMID:7752562 NCBI chr  X:29,020,377...29,241,666
Ensembl chr  X:29,020,557...29,241,666 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Strychnine inhibits the reaction [NAD inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased secretion of IL1B protein]] CTD PMID:29642561 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Strychnine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 multiple interactions ISO Strychnine binds to and results in decreased activity of SCN5A protein CTD PMID:21616062 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Strychnine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
Syrosingopine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO syrosingopine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
vincaleukoblastine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 decreases response to substance
increases expression		 ISO ABCA2 mRNA results in decreased susceptibility to Vinblastine
Vinblastine results in increased expression of ABCA2 mRNA		 CTD PMID:16928819 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 decreases response to substance
increases expression		 ISO ABCA3 mRNA results in decreased susceptibility to Vinblastine
Vinblastine results in increased expression of ABCA3 mRNA		 CTD PMID:16928819 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases uptake
decreases activity
multiple interactions
increases export		 ISO ABCB11 protein results in decreased uptake of Vinblastine
Vinblastine results in decreased activity of ABCB11 protein
Vinblastine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
ABCB11 protein results in increased export of Vinblastine		 CTD PMID:10617675 PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases response to substance
increases secretion
increases activity
increases expression
affects binding
multiple interactions
affects uptake
increases transport		 ISO
EXP		 ABCB1 protein results in decreased susceptibility to Vinblastine
ABCB1A protein results in increased secretion of Vinblastine
Vinblastine results in increased activity of ABCB1 protein mutant form
Vinblastine results in increased expression of ABCB1 protein
Vinblastine binds to ABCB1 protein
[Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]] which results in decreased susceptibility to Vinblastine; [Elacridar binds to and results in decreased activity of ABCB1 protein] which results in decreased export of Vinblastine; [Glycyrrhetinic Acid affects the activity of ABCB1 protein] which affects the susceptibility to Vinblastine; [sodium arsenite results in increased expression of ABCB1 protein] which results in decreased susceptibility to Vinblastine; [Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Carvedilol inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; Clotrimazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; cnidiadin inhibits the reaction [ABCB1 protein results in increased export of Vinblastine]; Curcumin analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Curcumin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Cyclosporine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Diazinon affects the reaction [ABCB1 protein results in increased transport of Vinblastine]; Erythromycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Ketoconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Miconazole inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Sesquiterpenes analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vinblastine]; Troleandomycin inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein affects the uptake of Vinblastine]; Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Vinblastine]; Vinblastine inhibits the reaction [Verapamil analog results in increased activity of ABCB1 protein mutant form]		 CTD PMID:1967174 PMID:8917702 PMID:9148857 PMID:11355955 PMID:11455017 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases secretion EXP ABCB1B protein results in increased secretion of Vinblastine CTD PMID:12235267 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
decreases response to substance		 ISO
EXP		 ABCC1 protein affects the susceptibility to Vinblastine
ABCC1 protein results in decreased susceptibility to Vinblastine		 CTD PMID:9334814 PMID:11455017 PMID:16156793 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects transport
decreases response to substance
multiple interactions		 ISO
EXP		 ABCC2 protein affects the transport of Vinblastine
ABCC2 protein results in decreased susceptibility to Vinblastine
[isopropyl 5,12-hydroxypentadeca-8,10-dien-6,14-diynoate results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine; [verlukast results in decreased activity of ABCC2 protein] which results in increased uptake of Vinblastine; Probenecid promotes the reaction [ABCC2 protein affects the transport of Vinblastine]		 CTD PMID:9525973 PMID:11455017 PMID:15849751 PMID:25844889 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Ablim1 actin-binding LIM protein 1 affects response to substance ISO ABLIM1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:256,083,747...256,372,075
Ensembl chr 1:256,084,297...256,371,969 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 affects response to substance ISO ACAT2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 affects response to substance ISO ACOT13 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:40,240,378...40,252,851
Ensembl chr17:40,240,378...40,252,851 		JBrowse link
G Acp1 acid phosphatase 1 affects response to substance ISO ACP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:47,506,380...47,522,021
Ensembl chr 6:47,506,380...47,522,021 		JBrowse link
G Add3 adducin 3 affects response to substance ISO ADD3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:252,147,341...252,255,126
Ensembl chr 1:252,147,386...252,255,124 		JBrowse link
G Aif1 allograft inflammatory factor 1 decreases expression EXP Vinblastine results in decreased expression of AIF1 mRNA CTD PMID:20624997 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression EXP Vinblastine results in decreased expression of AK1 mRNA CTD PMID:20624997 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041 		JBrowse link
G Aox1 aldehyde oxidase 1 affects response to substance ISO AOX1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770 		JBrowse link
G Apln apelin decreases expression EXP Vinblastine results in decreased expression of APLN mRNA CTD PMID:20624997 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Atp5me ATP synthase membrane subunit e affects response to substance ISO ATP5ME protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013 		JBrowse link
G Atp5mf ATP synthase membrane subunit f affects response to substance ISO ATP5MF protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236 		JBrowse link
G Aurkb aurora kinase B affects response to substance ISO AURKB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Axl Axl receptor tyrosine kinase affects response to substance ISO AXL protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 affects response to substance ISO BIRC2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 affects response to substance ISO BIRC3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 decreases response to substance ISO BIRC7 protein results in decreased susceptibility to Vinblastine CTD PMID:17437058 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase affects response to substance ISO BUB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G C10h5orf15 similar to human chromosome 5 open reading frame 15 affects response to substance ISO C5ORF15 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:36,563,989...36,576,593
Ensembl chr10:36,563,958...36,576,590 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions		 EXP
ISO		 Vinblastine results in increased cleavage of CASP3 protein
CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]		 CTD PMID:16545138 PMID:20624997 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase affects response to substance ISO CAT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Vinblastine results in increased expression of CCL2 mRNA CTD PMID:20624997 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccn2 cellular communication network factor 2 affects response to substance ISO CCN2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnb1 cyclin B1 affects response to substance
increases response to substance		 ISO CCNB1 protein affects the susceptibility to Vinblastine
CCNB1 protein results in increased susceptibility to Vinblastine		 CTD PMID:16217747 PMID:16849574 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 affects response to substance ISO CCNB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Cd14 CD14 molecule increases expression EXP Vinblastine results in increased expression of CD14 mRNA CTD PMID:20624997 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd40lg CD40 ligand decreases response to substance
multiple interactions		 ISO CD40LG protein results in decreased susceptibility to Vinblastine
CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]		 CTD PMID:16545138 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cd44 CD44 molecule increases expression EXP Vinblastine results in increased expression of CD44 mRNA CTD PMID:20624997 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cdca8 cell division cycle associated 8 affects response to substance ISO CDCA8 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 affects response to substance ISO CDK1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 affects response to substance ISO CDK2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Vinblastine results in increased expression of CDKN1A mRNA CTD PMID:20624997 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects response to substance ISO CDKN2C protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Vinblastine results in decreased expression of CDKN3 mRNA CTD PMID:20624997 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cenpa centromere protein A affects response to substance ISO CENPA protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 affects response to substance ISO CKAP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 affects response to substance ISO COX17 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cox5a cytochrome c oxidase subunit 5A affects response to substance ISO COX5A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781 		JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 affects response to substance ISO COX6B1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
Ensembl chr 2:85,875,109...85,884,001 		JBrowse link
G Cp ceruloplasmin increases expression EXP Vinblastine results in increased expression of CP mRNA CTD PMID:20624997 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 affects response to substance ISO CREG1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308 		JBrowse link
G Cript CXXC repeat containing interactor of PDZ3 domain affects response to substance ISO CRIPT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399 		JBrowse link
G Ctss cathepsin S increases expression EXP Vinblastine results in increased expression of CTSS mRNA CTD PMID:20624997 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Vinblastine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:11602686 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Dcps decapping enzyme, scavenger affects response to substance ISO DCPS protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:33,468,669...33,524,407
Ensembl chr 8:33,415,671...33,524,389 		JBrowse link
G Ddx23 DEAD-box helicase 23 affects response to substance ISO DDX23 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:129,797,620...129,814,909
Ensembl chr 7:129,797,614...129,814,949 		JBrowse link
G Dera deoxyribose-phosphate aldolase affects response to substance ISO DERA protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:170,663,689...170,742,469
Ensembl chr 4:170,663,665...170,758,865 		JBrowse link
G Dffb DNA fragmentation factor subunit beta affects response to substance ISO DFFB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dipk1a divergent protein kinase domain 1A affects response to substance ISO DIPK1A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:1,772,412...1,843,508
Ensembl chr14:1,772,422...1,843,743 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 affects response to substance ISO DKK1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 affects response to substance ISO DKK3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON affects response to substance ISO DONSON protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889 		JBrowse link
G Dscc1 DNA replication and sister chromatid cohesion 1 affects response to substance ISO DSCC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:86,482,588...86,498,212
Ensembl chr 7:86,482,588...86,498,212 		JBrowse link
G E2f1 E2F transcription factor 1 increases response to substance ISO E2F1 protein results in increased susceptibility to Vinblastine CTD PMID:16849574 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Ednrb endothelin receptor type B increases expression EXP Vinblastine results in increased expression of EDNRB mRNA CTD PMID:20624997 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Efcab7 EF-hand calcium binding domain 7 affects response to substance ISO EFCAB7 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:114,525,403...114,576,130
Ensembl chr 5:114,525,167...114,576,129 		JBrowse link
G Emp2 epithelial membrane protein 2 affects response to substance ISO EMP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:5,360,073...5,394,734
Ensembl chr10:5,360,073...5,394,733 		JBrowse link
G Epcam epithelial cell adhesion molecule affects response to substance ISO EPCAM protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 increases expression EXP Vinblastine results in increased expression of EPRS1 mRNA CTD PMID:20624997 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects response to substance ISO ERBB2 protein affects the susceptibility to Vinblastine CTD PMID:10327070 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Ereg epiregulin affects response to substance ISO EREG protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Esm1 endothelial cell-specific molecule 1 decreases expression EXP Vinblastine results in decreased expression of ESM1 mRNA CTD PMID:20624997 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects response to substance ISO ETFB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068 		JBrowse link
G Exosc9 exosome component 9 affects response to substance ISO EXOSC9 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:119,416,028...119,426,981
Ensembl chr 2:119,388,715...119,427,051 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression EXP Vinblastine results in increased expression of F3 mRNA CTD PMID:20624997 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C affects response to substance ISO FAM3C protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078 		JBrowse link
G Fancl FA complementation group L affects response to substance ISO FANCL protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:100,249,733...100,317,958
Ensembl chr14:100,248,875...100,314,255 		JBrowse link
G Faslg Fas ligand increases expression ISO Vinblastine results in increased expression of FASLG protein CTD PMID:11716366 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP Vinblastine results in increased expression of FCGR2B mRNA CTD PMID:20624997 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 affects response to substance ISO FEN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A affects response to substance ISO FKBP1A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Fli1 Fli-1 proto-oncogene, ETS transcription factor affects response to substance ISO FLI1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:30,831,422...30,950,468
Ensembl chr 8:30,832,753...30,950,433 		JBrowse link
G Fn1 fibronectin 1 affects response to substance ISO FN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit affects response to substance ISO FOSL1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G G0s2 G0/G1switch 2 affects response to substance ISO G0S2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP Vinblastine results in increased expression of GADD45A mRNA CTD PMID:20624997 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression EXP Vinblastine results in increased expression of GADD45B mRNA CTD PMID:20624997 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP Vinblastine results in increased expression of GADD45G mRNA CTD PMID:20624997 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Gas7 growth arrest specific 7 decreases expression EXP Vinblastine results in decreased expression of GAS7 mRNA CTD PMID:20624997 NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276 		JBrowse link
G Ggct gamma-glutamyl cyclotransferase affects response to substance ISO GGCT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:84,122,921...84,129,327
Ensembl chr 4:84,123,118...84,129,277 		JBrowse link
G Ggcx gamma-glutamyl carboxylase affects response to substance ISO GGCX protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063 		JBrowse link
G Gmnn geminin, DNA replication inhibitor affects response to substance ISO GMNN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:40,301,771...40,310,054
Ensembl chr17:40,301,808...40,310,054 		JBrowse link
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta affects response to substance ISO GNPTAB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933 		JBrowse link
G Gpr176 G protein-coupled receptor 176 affects response to substance ISO GPR176 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:105,236,794...105,337,664
Ensembl chr 3:105,236,795...105,337,226 		JBrowse link
G Gpsm2 G-protein signaling modulator 2 affects response to substance ISO GPSM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases response to substance EXP GSTP1 protein results in decreased susceptibility to Vinblastine CTD PMID:11455017 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gtf2i general transcription factor II I affects response to substance ISO GTF2I protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243 		JBrowse link
G Gtf3a general transcription factor III A affects response to substance ISO GTF3A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:8,136,746...8,144,690
Ensembl chr12:8,136,747...8,144,690 		JBrowse link
G Gtse1 G-2 and S-phase expressed 1 affects response to substance ISO GTSE1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806 		JBrowse link
G Gusb glucuronidase, beta affects response to substance ISO GUSB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:26,701,188...26,714,718
Ensembl chr12:26,697,951...26,726,905 		JBrowse link
G H1f2 H1.2 linker histone, cluster member affects response to substance ISO H1-2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635 		JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase affects response to substance ISO HADH protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 affects response to substance ISO HCLS1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014 		JBrowse link
G Hmgb1 high mobility group box 1 affects response to substance ISO HMGB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgb2 high mobility group box 2 affects response to substance ISO HMGB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmgn3 high mobility group nucleosomal binding domain 3 affects response to substance ISO HMGN3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976 		JBrowse link
G Hmmr hyaluronan-mediated motility receptor affects response to substance ISO HMMR protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP Vinblastine results in increased expression of HMOX1 mRNA CTD PMID:20624997 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Homer1 homer scaffold protein 1 affects response to substance ISO HOMER1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
decreases expression		 EXP
ISO		 Vinblastine results in increased expression of ICAM1 mRNA
Vinblastine results in decreased expression of ICAM1 mRNA; Vinblastine results in decreased expression of ICAM1 protein		 CTD PMID:12649748 PMID:20624997 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 affects response to substance ISO ID2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 affects response to substance ISO IDH2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 affects response to substance ISO IGF2BP3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta increases phosphorylation
multiple interactions		 ISO Vinblastine results in increased phosphorylation of IKBKB protein
Vinblastine results in decreased localization of [IKBKB protein binds to NFKBIA protein]		 CTD PMID:17029595 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 affects response to substance ISO IL13RA2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:111,002,590...111,074,053
Ensembl chr  X:111,002,592...111,072,381 		JBrowse link
G Il1b interleukin 1 beta affects response to substance
increases expression		 ISO
EXP		 IL1B protein affects the susceptibility to Vinblastine
Vinblastine results in increased expression of IL1B mRNA		 CTD PMID:16217747 PMID:20624997 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases chemical synthesis
increases stability		 ISO Vinblastine results in decreased chemical synthesis of IL6 protein
Vinblastine results in increased stability of IL6 mRNA		 CTD PMID:16499908 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Vinblastine results in decreased expression of INHA mRNA CTD PMID:20624997 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inhba inhibin subunit beta A affects response to substance ISO INHBA protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Itgal integrin subunit alpha L decreases expression ISO Vinblastine results in decreased expression of ITGAL mRNA; Vinblastine results in decreased expression of ITGAL protein CTD PMID:12649748 NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 affects response to substance ISO ITGB1BP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases phosphorylation		 ISO TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein] CTD PMID:12221076 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kank1 KN motif and ankyrin repeat domains 1 affects response to substance ISO KANK1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:222,877,962...223,074,514
Ensembl chr 1:222,877,622...223,074,514 		JBrowse link
G Kazn kazrin, periplakin interacting protein affects response to substance ISO KAZN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:154,392,793...155,381,567
Ensembl chr 5:154,392,793...154,779,074 		JBrowse link
G Kif11 kinesin family member 11 affects response to substance ISO KIF11 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766 		JBrowse link
G Kif15 kinesin family member 15 affects response to substance ISO KIF15 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750 		JBrowse link
G Kif1b kinesin family member 1B affects response to substance ISO KIF1B protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Kif20a kinesin family member 20A affects response to substance ISO KIF20A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Kif23 kinesin family member 23 affects response to substance ISO KIF23 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072 		JBrowse link
G Kif4a kinesin family member 4A affects response to substance ISO KIF4A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:65,721,746...65,824,277
Ensembl chr  X:65,721,779...65,824,139 		JBrowse link
G Kpna2 karyopherin subunit alpha 2 affects response to substance ISO KPNA2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150 		JBrowse link
G Lmnb1 lamin B1 affects response to substance ISO LMNB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 affects response to substance ISO LPAR1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Lrrc1 leucine rich repeat containing 1 affects response to substance ISO LRRC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:78,239,897...78,407,347
Ensembl chr 8:78,239,900...78,406,490 		JBrowse link
G Lsm7 LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated affects response to substance ISO LSM7 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:8,856,698...8,859,113
Ensembl chr 7:8,856,489...8,859,119 		JBrowse link
G Ltbp2 latent transforming growth factor beta binding protein 2 affects response to substance ISO LTBP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:104,429,947...104,530,498
Ensembl chr 6:104,429,947...104,526,208 		JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 affects response to substance ISO MAD2L1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 ISO Vinblastine results in increased phosphorylation of MAPK8 protein
TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein]		 CTD PMID:12221076 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 ISO TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein] CTD PMID:12221076 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapkapk5 MAPK activated protein kinase 5 affects response to substance ISO MAPKAPK5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:34,993,520...35,013,059
Ensembl chr12:34,994,092...35,013,052 		JBrowse link
G Melk maternal embryonic leucine zipper kinase affects response to substance ISO MELK protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:58,540,393...58,600,562
Ensembl chr 5:58,540,449...58,600,937 		JBrowse link
G Mme membrane metallo-endopeptidase affects response to substance ISO MME protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792 		JBrowse link
G Mmp1 matrix metallopeptidase 1 affects response to substance ISO MMP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mok MOK protein kinase affects response to substance ISO MOK protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:129,823,794...129,854,669
Ensembl chr 6:129,823,795...129,854,700 		JBrowse link
G Mrpl57 mitochondrial ribosomal protein L57 affects response to substance ISO MRPL57 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:31,970,904...31,971,766
Ensembl chr15:31,970,860...31,973,993 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects response to substance
increases expression		 ISO
EXP		 MYC protein affects the susceptibility to Vinblastine
Vinblastine results in increased expression of MYC mRNA		 CTD PMID:18802399 PMID:20624997 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycbp Myc binding protein affects response to substance ISO MYCBP protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:136,135,955...136,143,163
Ensembl chr 5:136,135,931...136,145,616 		JBrowse link
G Nbn nibrin increases expression EXP Vinblastine results in increased expression of NBN mRNA CTD PMID:20624997 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G affects response to substance ISO NCAPG protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H affects response to substance ISO NCAPH protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ndc80 NDC80 kinetochore complex component affects response to substance ISO NDC80 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924 		JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 affects response to substance ISO NDUFA1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:116,424,223...116,427,875
Ensembl chr  X:116,424,223...116,428,633 		JBrowse link
G Ndufa13 NADH:ubiquinone oxidoreductase subunit A13 affects response to substance ISO NDUFA13 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:19,526,633...19,533,567
Ensembl chr16:19,526,565...19,535,726 		JBrowse link
G Ndufa3 NADH:ubiquinone oxidoreductase subunit A3 affects response to substance ISO NDUFA3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:65,597,567...65,600,197
Ensembl chr 1:65,597,578...65,600,235 		JBrowse link
G Ndufa7 NADH:ubiquinone oxidoreductase subunit A7 affects response to substance ISO NDUFA7 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:14,609,283...14,622,064
Ensembl chr 7:14,609,146...14,631,976 		JBrowse link
G Ndufb2 NADH:ubiquinone oxidoreductase subunit B2 affects response to substance ISO NDUFB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:68,367,526...68,374,609
Ensembl chr15:46,536,062...46,536,851
Ensembl chr 4:46,536,062...46,536,851 		JBrowse link
G Ndufc1 NADH:ubiquinone oxidoreductase subunit C1 affects response to substance ISO NDUFC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:135,447,067...135,450,950
Ensembl chr 2:135,447,119...135,450,874 		JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 affects response to substance ISO NDUFC2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189 		JBrowse link
G Ndufs6 NADH:ubiquinone oxidoreductase subunit S6 affects response to substance ISO NDUFS6 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:29,968,833...29,977,423
Ensembl chr 1:29,968,842...29,977,467 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 affects response to substance ISO NDUFV2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 decreases localization ISO Vinblastine results in decreased localization of NFATC4 protein CTD PMID:17044076 NCBI chr15:29,286,998...29,314,610
Ensembl chr15:29,305,535...29,314,610 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation
multiple interactions		 ISO Vinblastine results in increased phosphorylation of NFKBIA protein
Vinblastine results in decreased localization of [IKBKB protein binds to NFKBIA protein]		 CTD PMID:17029595 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngf nerve growth factor decreases response to substance EXP Vinblastine results in decreased susceptibility to NGF protein CTD PMID:9524088 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Npy neuropeptide Y decreases expression EXP Vinblastine results in decreased expression of NPY mRNA CTD PMID:1671012 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Vinblastine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity		 ISO [Vinblastine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; NR1I2 protein promotes the reaction [Vinblastine results in increased expression of ABCB1 protein] CTD PMID:20041327 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nsmaf neutral sphingomyelinase activation associated factor affects response to substance ISO NSMAF protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 5:19,517,795...19,578,773
Ensembl chr 5:19,518,348...19,577,627 		JBrowse link
G Nudt15 nudix hydrolase 15 affects response to substance ISO NUDT15 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:48,707,776...48,713,847
Ensembl chr15:48,709,700...48,747,363 		JBrowse link
G Nudt4 nudix hydrolase 4 affects response to substance ISO NUDT4 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:30,188,100...30,204,615
Ensembl chr 7:30,188,100...30,204,615 		JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 affects response to substance ISO NUSAP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:106,603,273...106,633,428
Ensembl chr 3:106,603,289...106,633,624 		JBrowse link
G Oaz1 ornithine decarboxylase antizyme 1 affects response to substance ISO OAZ1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:8,883,855...8,886,315
Ensembl chr 7:8,883,851...8,886,310 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions ISO Vinblastine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] CTD PMID:9270009 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Oip5 Opa interacting protein 5 affects response to substance ISO OIP5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 3:106,593,746...106,603,281
Ensembl chr 3:106,593,760...106,603,250 		JBrowse link
G Or1i2 olfactory receptor family 1 subfamily I member 2 affects response to substance ISO OR1I1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:10,985,938...10,986,879
Ensembl chr 7:10,980,344...10,987,036 		JBrowse link
G Orc6 origin recognition complex, subunit 6 affects response to substance ISO ORC6 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662 		JBrowse link
G Osbpl10 oxysterol binding protein-like 10 affects response to substance ISO OSBPL10 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:114,661,050...114,918,664
Ensembl chr 8:114,660,743...114,918,625 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO CD40LG protein inhibits the reaction [Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; Vinblastine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein] CTD PMID:16545138 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pdhb pyruvate dehydrogenase E1 subunit beta affects response to substance ISO PDHB protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500 		JBrowse link
G Pelo pelota mRNA surveillance and ribosome rescue factor affects response to substance ISO PELO protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:46,797,853...46,799,621
Ensembl chr 2:46,797,853...46,799,746 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects response to substance ISO PGRMC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682 		JBrowse link
G Pir pirin affects response to substance ISO PIR protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218 		JBrowse link
G Plagl1 PLAG1 like zinc finger 1 increases expression EXP Vinblastine results in increased expression of PLAGL1 mRNA CTD PMID:20624997 NCBI chr 1:7,477,295...7,517,229
Ensembl chr 1:7,477,177...7,517,228 		JBrowse link
G Plat plasminogen activator, tissue type increases expression EXP Vinblastine results in increased expression of PLAT mRNA CTD PMID:20624997 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase affects response to substance ISO PLAU protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression EXP Vinblastine results in increased expression of PLAUR mRNA CTD PMID:20624997 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP Vinblastine results in increased expression of PPP1R15A mRNA CTD PMID:20624997 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 affects response to substance ISO PRC1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765 		JBrowse link
G Prkcd protein kinase C, delta affects localization ISO Vinblastine affects the localization of PRKCD protein CTD PMID:9852137 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects response to substance ISO PSMB1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560 		JBrowse link
G Psme4 proteasome activator subunit 4 affects response to substance ISO PSME4 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408 		JBrowse link
G Ptges3 prostaglandin E synthase 3 affects response to substance ISO PTGES3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin affects response to substance ISO PTTG1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837 		JBrowse link
G Ptx3 pentraxin 3 affects response to substance ISO PTX3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Qrich1 glutamine-rich 1 increases phosphorylation ISO Vinblastine results in increased phosphorylation of QRICH1 protein CTD PMID:17510977 NCBI chr 8:109,216,900...109,256,472
Ensembl chr 8:109,217,376...109,261,359 		JBrowse link
G Rab11fip1 RAB11 family interacting protein 1 affects response to substance ISO RAB11FIP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:64,886,902...64,917,491
Ensembl chr16:64,884,676...64,917,491 		JBrowse link
G Racgap1 Rac GTPase-activating protein 1 affects response to substance ISO RACGAP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831 		JBrowse link
G Ranbp1 RAN binding protein 1 affects response to substance ISO RANBP1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838 		JBrowse link
G Rassf1 Ras association domain family member 1 increases expression EXP Vinblastine results in increased expression of RASSF1 mRNA CTD PMID:20624997 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit affects response to substance ISO REV3L protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099 		JBrowse link
G Rfc5 replication factor C subunit 5 affects response to substance ISO RFC5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312 		JBrowse link
G Rpa3 replication protein A3 affects response to substance ISO RPA3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 affects response to substance ISO RRM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP Vinblastine results in increased expression of S100A8 mRNA CTD PMID:20624997 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP Vinblastine results in increased expression of S100A9 mRNA CTD PMID:20624997 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sele selectin E increases expression EXP Vinblastine results in increased expression of SELE mRNA CTD PMID:20624997 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Serpinb2 serpin family B member 2 affects response to substance ISO SERPINB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Serpine1 serpin family E member 1 increases expression
affects response to substance		 EXP
ISO		 Vinblastine results in increased expression of SERPINE1 mRNA
SERPINE1 protein affects the susceptibility to Vinblastine		 CTD PMID:16217747 PMID:20624997 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sfxn1 sideroflexin 1 affects response to substance ISO SFXN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529 		JBrowse link
G Shtn1 shootin 1 affects response to substance ISO SHTN1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:258,121,966...258,225,861
Ensembl chr 1:258,121,968...258,228,265 		JBrowse link
G Skic8 SKI8 subunit of superkiller complex affects response to substance ISO SKIC8 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:55,103,542...55,120,837
Ensembl chr 8:55,103,545...55,120,813 		JBrowse link
G Skp2 S-phase kinase associated protein 2 affects response to substance ISO SKP2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 affects response to substance ISO SLC22A3 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Snrnp25 small nuclear ribonucleoprotein U11/U12 subunit 25 affects response to substance ISO SNRNP25 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:15,420,482...15,423,806
Ensembl chr10:15,420,486...15,423,804 		JBrowse link
G Snx10 sorting nexin 10 affects response to substance ISO SNX10 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:80,612,648...80,677,005
Ensembl chr 4:80,612,669...80,676,996 		JBrowse link
G Sod1 superoxide dismutase 1 affects response to substance ISO SOD1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression		 ISO bisindolylmaleimide I inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; calphostin C inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA] CTD PMID:9852137 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sort1 sortilin 1 affects response to substance ISO SORT1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Spon1 spondin 1 increases expression EXP Vinblastine results in increased expression of SPON1 mRNA CTD PMID:20624997 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 affects response to substance ISO SRD5A1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srgn serglycin affects response to substance ISO SRGN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO Vinblastine deficiency results in decreased activity of and affects the localization of STAT1 protein CTD PMID:28086195 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Vinblastine deficiency results in decreased activity of and affects the localization of STAT3 protein CTD PMID:28086195 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stc2 stanniocalcin 2 affects response to substance ISO STC2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Stk26 serine/threonine kinase 26 affects response to substance ISO STK26 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr  X:130,325,064...130,375,674
Ensembl chr  X:130,310,885...130,374,291 		JBrowse link
G Strn striatin affects response to substance ISO STRN protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:16,335,265...16,422,159
Ensembl chr 6:16,335,358...16,417,083 		JBrowse link
G Sucla2 succinate-CoA ligase ADP-forming subunit beta affects response to substance ISO SUCLA2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138 		JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects response to substance ISO SUCLG1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 affects response to substance ISO SULT1A1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Syde1 synapse defective Rho GTPase homolog 1 affects response to substance ISO SYDE1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:11,032,931...11,038,917
Ensembl chr 7:11,032,898...11,039,869 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 affects response to substance ISO TBC1D4 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
G Tdg thymine-DNA glycosylase affects response to substance ISO TDG protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:21,077,853...21,097,617
Ensembl chr 7:21,077,853...21,097,567 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 affects response to substance
increases expression		 ISO
EXP		 TFPI2 protein affects the susceptibility to Vinblastine
Vinblastine results in increased expression of TFPI2 mRNA		 CTD PMID:16217747 PMID:20624997 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600 		JBrowse link
G Thbd thrombomodulin increases expression EXP Vinblastine results in increased expression of THBD mRNA CTD PMID:20624997 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Vinblastine results in increased expression of THBS1 mRNA CTD PMID:20624997 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP Vinblastine results in increased expression of TIMP1 mRNA CTD PMID:20624997 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tmem134 transmembrane protein 134 affects response to substance ISO TMEM134 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:201,419,225...201,424,778
Ensembl chr 1:201,419,264...201,431,411 		JBrowse link
G Tmem14a transmembrane protein 14A affects response to substance ISO TMEM14A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 9:23,640,594...23,652,379
Ensembl chr 9:23,733,039...23,734,463
Ensembl chr 9:23,733,039...23,734,463 		JBrowse link
G Tmem156 transmembrane protein 156 affects response to substance ISO TMEM156 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:43,221,464...43,252,453
Ensembl chr14:43,223,381...43,252,449 		JBrowse link
G Tmem97 transmembrane protein 97 affects response to substance ISO TMEM97 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730 		JBrowse link
G Tmpo thymopoietin affects response to substance ISO TMPO protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Top2a DNA topoisomerase II alpha affects response to substance ISO TOP2A protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of JUN protein]; TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK8 protein]; TP53 protein affects the reaction [Vinblastine results in increased phosphorylation of MAPK9 protein] CTD PMID:12221076 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpd52l1 TPD52 like 1 increases expression
affects response to substance		 EXP
ISO		 Vinblastine results in increased expression of TPD52L1 mRNA
TPD52L1 protein affects the susceptibility to Vinblastine		 CTD PMID:16217747 PMID:20624997 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Trim2 tripartite motif-containing 2 affects response to substance ISO TRIM2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:169,500,628...169,652,855
Ensembl chr 2:169,500,634...169,652,927 		JBrowse link
G Trmt5 tRNA methyltransferase 5 affects response to substance ISO TRMT5 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:91,963,558...91,987,660
Ensembl chr 6:91,943,724...91,987,555 		JBrowse link
G Tspan13 tetraspanin 13 affects response to substance ISO TSPAN13 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:52,738,748...52,765,503
Ensembl chr 6:52,738,758...52,765,547 		JBrowse link
G Ttf2 transcription termination factor 2 affects response to substance ISO TTF2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 2:188,366,321...188,397,750
Ensembl chr 2:188,366,331...188,397,689 		JBrowse link
G Ttk Ttk protein kinase affects response to substance ISO TTK protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651 		JBrowse link
G Tuba1b tubulin, alpha 1B decreases expression EXP Vinblastine results in decreased expression of TUBA1B mRNA CTD PMID:20624997 NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tuba4a tubulin, alpha 4A decreases expression EXP Vinblastine results in decreased expression of TUBA4A mRNA CTD PMID:20624997 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Vinblastine results in decreased expression of TUBB4B mRNA CTD PMID:20624997 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296 		JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression EXP Vinblastine results in decreased expression of TUBB5 mRNA CTD PMID:20624997 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Tubg1 tubulin, gamma 1 decreases expression EXP Vinblastine results in decreased expression of TUBG1 mRNA CTD PMID:20624997 NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433 		JBrowse link
G Uqcr10 ubiquinol-cytochrome c reductase, complex III subunit X affects response to substance ISO UQCR10 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr14:79,566,151...79,569,017
Ensembl chr14:79,566,157...79,569,003 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression EXP Vinblastine results in increased expression of VCAM1 mRNA CTD PMID:20624997 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression EXP Vinblastine results in decreased expression of VEGFA mRNA CTD PMID:20624997 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfc vascular endothelial growth factor C affects response to substance ISO VEGFC protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Vwf von Willebrand factor increases expression EXP Vinblastine results in increased expression of VWF mRNA CTD PMID:20624997 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wsb2 WD repeat and SOCS box-containing 2 affects response to substance ISO WSB2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr12:39,217,645...39,238,634
Ensembl chr12:39,217,648...39,238,640 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta affects response to substance ISO YWHAQ protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273 		JBrowse link
G Zdhhc11 zinc finger, DHHC-type containing 11 affects response to substance ISO ZDHHC11 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 1:29,296,334...29,327,227
Ensembl chr 1:29,296,334...29,326,898 		JBrowse link
G Zfp36l2 zinc finger protein 36, C3H type-like 2 affects response to substance ISO ZFP36L2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064 		JBrowse link
G Zwint ZW10 interacting kinetochore protein affects response to substance ISO ZWINT protein affects the susceptibility to Vinblastine CTD PMID:16217747 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957 		JBrowse link
vincamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 multiple interactions ISO Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IBA1 protein] CTD PMID:38629493 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GFAP protein] CTD PMID:38629493 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of HMOX1 protein] CTD PMID:38629493 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B mRNA]; Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL1B protein] CTD PMID:38629493 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL6 mRNA]; Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of IL6 protein] CTD PMID:38629493 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Vincamine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions ISO Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of NFE2L2 protein] CTD PMID:38629493 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased phosphorylation of NFKBIA protein] CTD PMID:38629493 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased phosphorylation of RELA protein] CTD PMID:38629493 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF mRNA]; Vincamine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF protein] CTD PMID:38629493 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
vincristine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aamdc adipogenesis associated, Mth938 domain containing increases expression ISO Vincristine results in increased expression of AAMDC mRNA CTD PMID:23649840 NCBI chr 1:151,861,990...151,893,621
Ensembl chr 1:151,845,255...151,892,398 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA1 mRNA CTD PMID:19944135 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abca12 ATP binding cassette subfamily A member 12 increases expression
multiple interactions		 ISO Vincristine results in increased expression of ABCA12 mRNA
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA12 mRNA		 CTD PMID:19944135 PMID:23649840 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Abca4 ATP binding cassette subfamily A member 4 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCA4 mRNA CTD PMID:19944135 NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069 		JBrowse link
G Abca5 ATP binding cassette subfamily A member 5 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCA5 mRNA CTD PMID:19944135 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976 		JBrowse link
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCA8 mRNA CTD PMID:19944135 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects response to substance
increases expression
multiple interactions
increases transport
decreases uptake
decreases response to substance
affects uptake		 ISO
EXP		 ABCB1 protein affects the susceptibility to Vincristine
Vincristine results in increased expression of ABCB1A mRNA
Vincristine results in increased expression of ABCB1 protein
[Estradiol results in decreased expression of ABCB1 protein] which results in increased uptake of and results in increased susceptibility to Vincristine; [MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Vincristine; [Paclitaxel results in increased expression of ABCB1] which results in decreased susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB1 mRNA; [Vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; CEP 33779 inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Cyclosporine inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Fenofibrate inhibits the reaction [ABCB1 protein results in increased transport of Vincristine]; Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; NR1I2 protein promotes the reaction [Vincristine results in increased expression of ABCB1 protein]; pinostrobin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; tectochrysin inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]; zosuquidar trihydrochloride inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]
ABCB1 protein results in decreased uptake of Vincristine
ABCB1 protein affects the uptake of Vincristine		 CTD PMID:7905786 PMID:10617675 PMID:11792417 PMID:11934808 PMID:15239124 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects uptake EXP ABCB1B protein affects the uptake of Vincristine CTD PMID:11934808 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB4 mRNA CTD PMID:19944135 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 multiple interactions
decreases response to substance		 ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB6 mRNA
ABCB6 protein results in decreased susceptibility to Vincristine		 CTD PMID:19944135 PMID:25202056 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases response to substance
increases expression
multiple interactions
decreases response to substance
affects transport
affects response to substance
affects export		 ISO
EXP		 ABCC1 gene SNP results in increased susceptibility to Vincristine
Vincristine results in increased expression of ABCC1 mRNA
[Genistein results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Indomethacin results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Probenecid results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [Sulfinpyrazone results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine; [verlukast results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine
ABCC1 protein results in decreased susceptibility to Vincristine; ABCC1 results in decreased susceptibility to Vincristine
[MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC1 mRNA; ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine; Buthionine Sulfoximine inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Cyclosporine inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Doxorubicin inhibits the reaction [ABCC1 protein affects the transport of Vincristine]; GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Quercetin promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Verapamil inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; Vincristine inhibits the reaction [ABCC1 protein affects the transport of fluorexon]; Vincristine inhibits the reaction [Glutathione promotes the reaction [ABCC1 results in increased transport of methylarsine analog]]; zafirlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]
ABCC1 protein affects the transport of Vincristine; ABCC1 protein mutant form affects the transport of Vincristine
ABCC1 protein affects the susceptibility to Vincristine		 CTD PMID:7954421 PMID:8649356 PMID:8968083 PMID:10348353 PMID:10685512 More... NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc10 ATP binding cassette subfamily C member 10 multiple interactions
decreases response to substance		 ISO Imatinib Mesylate inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine]; nilotinib inhibits the reaction [ABCC10 protein results in decreased susceptibility to Vincristine] CTD PMID:19841739 NCBI chr 9:14,657,242...14,677,178
Ensembl chr 9:14,657,264...14,677,178 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
multiple interactions
decreases response to substance		 ISO ABCC2 protein affects the export of Vincristine
[Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC2 mRNA; ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine; myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine]		 CTD PMID:15896345 PMID:19944135 PMID:22095822 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCC3 mRNA CTD PMID:19944135 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCC4 mRNA CTD PMID:19944135 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCC5 mRNA CTD PMID:19944135 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCC6 mRNA CTD PMID:19944135 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCD3 mRNA CTD PMID:19944135 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCG1 mRNA CTD PMID:19944135 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO [Paclitaxel results in decreased expression of ABCG2] which results in decreased susceptibility to Vincristine; [Vincristine results in decreased susceptibility to Vincristine] which results in increased expression of ABCG2 mRNA CTD PMID:19944135 PMID:21833476 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abcg4 ATP binding cassette subfamily G member 4 multiple interactions ISO [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCG4 mRNA CTD PMID:19944135 NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881 		JBrowse link
G Abhd11 abhydrolase domain containing 11 decreases expression ISO Vincristine results in decreased expression of ABHD11 mRNA CTD PMID:23649840 NCBI chr12:21,682,206...21,685,331
Ensembl chr12:21,682,202...21,685,398 		JBrowse link
G Abtb2 ankyrin repeat and BTB domain containing 2 increases expression ISO Vincristine results in increased expression of ABTB2 mRNA CTD PMID:23649840 NCBI chr 3:89,954,726...90,108,549
Ensembl chr 3:89,954,713...90,108,548 		JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 decreases expression ISO Vincristine results in decreased expression of ACAD9 mRNA CTD PMID:23649840 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547 		JBrowse link
G Ache acetylcholinesterase decreases expression
multiple interactions		 EXP Vincristine results in decreased expression of ACHE protein
xaliproden inhibits the reaction [Vincristine results in decreased expression of ACHE protein]		 CTD PMID:8413926 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Ackr3 atypical chemokine receptor 3 increases expression ISO Vincristine results in increased expression of ACKR3 mRNA CTD PMID:23649840 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237 		JBrowse link
G Actr2 actin related protein 2 increases expression ISO Vincristine results in increased expression of ACTR2 mRNA CTD PMID:23649840 NCBI chr14:94,296,443...94,333,735
Ensembl chr14:94,296,443...94,340,524 		JBrowse link
G Adat2 adenosine deaminase, tRNA-specific 2 decreases expression ISO Vincristine results in decreased expression of ADAT2 mRNA CTD PMID:23649840 NCBI chr 1:7,954,520...7,975,254
Ensembl chr 1:7,954,631...7,975,251 		JBrowse link
G Adgrf4 adhesion G protein-coupled receptor F4 increases expression ISO Vincristine results in increased expression of ADGRF4 mRNA CTD PMID:23649840 NCBI chr 9:18,272,050...18,303,219
Ensembl chr 9:18,272,050...18,303,217 		JBrowse link
G Adrb1 adrenoceptor beta 1 decreases expression ISO Vincristine results in decreased expression of ADRB1 mRNA CTD PMID:23649840 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 increases response to substance ISO ADRB2 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Agbl3 AGBL carboxypeptidase 3 decreases expression ISO Vincristine results in decreased expression of AGBL3 mRNA CTD PMID:23649840 NCBI chr 4:63,448,789...63,535,538
Ensembl chr 4:63,453,940...63,531,188 		JBrowse link
G Ahsa2 activator of HSP90 ATPase homolog 2 decreases expression ISO Vincristine results in decreased expression of AHSA2P mRNA CTD PMID:23649840 NCBI chr14:97,476,304...97,485,725
Ensembl chr14:97,476,817...97,485,657 		JBrowse link
G Aim2 absent in melanoma 2 increases expression ISO Vincristine results in increased expression of AIM2 mRNA CTD PMID:23649840 NCBI chr13:85,865,206...85,906,996
Ensembl chr13:85,866,284...85,906,975 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression EXP Vincristine results in decreased expression of AK1 mRNA CTD PMID:20624997 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041 		JBrowse link
G Ak3 adenylate kinase 3 decreases expression ISO Vincristine results in decreased expression of AK3 mRNA CTD PMID:23649840 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625 		JBrowse link
G Akap10 A-kinase anchoring protein 10 increases expression ISO Vincristine results in increased expression of AKAP10 mRNA CTD PMID:23649840 NCBI chr10:46,545,371...46,608,730
Ensembl chr10:46,551,532...46,608,769 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
decreases expression		 ISO
EXP		 Vincristine inhibits the reaction [Doxorubicin results in decreased phosphorylation of AKT1 protein]
Vincristine results in decreased expression of AKT1 mRNA
Quercetin inhibits the reaction [Vincristine results in decreased expression of AKT1 mRNA]
Vincristine promotes the reaction [NVP ADW742 inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]]		 CTD PMID:16740780 PMID:18590705 PMID:33038355 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases expression
multiple interactions		 EXP Vincristine results in decreased expression of AKT2 mRNA
Quercetin inhibits the reaction [Vincristine results in decreased expression of AKT2 mRNA]		 CTD PMID:33038355 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression ISO Vincristine results in decreased expression of ALDOC mRNA CTD PMID:23649840 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Alms1 ALMS1, centrosome and basal body associated protein decreases expression ISO Vincristine results in decreased expression of ALMS1 mRNA CTD PMID:23649840 NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005 		JBrowse link
G Alpk2 alpha-kinase 2 increases expression ISO Vincristine results in increased expression of ALPK2 mRNA CTD PMID:23649840 NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258 		JBrowse link
G Amh anti-Mullerian hormone decreases secretion ISO Vincristine results in decreased secretion of AMH protein CTD PMID:30657998 NCBI chr 7:8,906,776...8,909,192
Ensembl chr 7:8,906,836...8,909,282 		JBrowse link
G Anapc5 anaphase-promoting complex subunit 5 increases expression ISO Vincristine results in increased expression of ANAPC5 mRNA CTD PMID:23649840 NCBI chr12:33,748,709...33,781,709
Ensembl chr12:33,748,735...33,781,781 		JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A decreases expression ISO Vincristine results in decreased expression of ANKDD1A mRNA CTD PMID:23649840 NCBI chr 8:66,017,571...66,043,738
Ensembl chr 8:66,017,773...66,042,651 		JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 increases expression ISO Vincristine results in increased expression of ANKHD1 mRNA CTD PMID:23649840 NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024 		JBrowse link
G Ankra2 ankyrin repeat family A member 2 increases expression ISO Vincristine results in increased expression of ANKRA2 mRNA CTD PMID:23649840 NCBI chr 2:29,612,867...29,623,748
Ensembl chr 2:29,612,925...29,623,730 		JBrowse link
G Ankrd13c ankyrin repeat domain 13C decreases expression ISO Vincristine results in decreased expression of ANKRD13C mRNA CTD PMID:23649840 NCBI chr 2:247,023,040...247,070,433
Ensembl chr 2:247,022,286...247,070,433 		JBrowse link
G Ankrd33b ankyrin repeat domain 33B increases expression ISO Vincristine results in increased expression of ANKRD33B mRNA CTD PMID:23649840 NCBI chr 2:82,277,604...82,359,420
Ensembl chr 2:82,283,108...82,358,872 		JBrowse link
G Ankrd37 ankyrin repeat domain 37 decreases expression ISO Vincristine results in decreased expression of ANKRD37 mRNA CTD PMID:23649840 NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E decreases expression ISO Vincristine results in decreased expression of ANP32E mRNA CTD PMID:23649840 NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054 		JBrowse link
G Anxa1 annexin A1 increases expression ISO Vincristine results in increased expression of ANXA1 mRNA CTD PMID:23649840 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa2 annexin A2 increases expression ISO Vincristine results in increased expression of ANXA2 mRNA CTD PMID:23649840 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 decreases expression ISO Vincristine results in decreased expression of AP1S2 mRNA CTD PMID:23649840 NCBI chr  X:30,572,746...30,598,961
Ensembl chr  X:30,572,751...30,597,262 		JBrowse link
G Apex2 apurinic/apyrimidinic endodeoxyribonuclease 2 decreases expression ISO Vincristine results in decreased expression of APEX2 mRNA CTD PMID:23649840 NCBI chr  X:19,425,684...19,508,459
Ensembl chr  X:19,487,419...19,508,439 		JBrowse link
G Apln apelin decreases expression EXP Vincristine results in decreased expression of APLN mRNA CTD PMID:20624997 NCBI chr  X:127,180,801...127,213,567
Ensembl chr  X:127,203,823...127,213,391 		JBrowse link
G Apod apolipoprotein D increases expression ISO Vincristine results in increased expression of APOD mRNA CTD PMID:23649840 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Apold1 apolipoprotein L domain containing 1 increases expression ISO Vincristine results in increased expression of APOLD1 mRNA CTD PMID:23649840 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706 		JBrowse link
G Aqp9 aquaporin 9 increases expression ISO Vincristine results in increased expression of AQP9 mRNA CTD PMID:23649840 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Arap2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 decreases expression ISO Vincristine results in decreased expression of ARAP2 mRNA CTD PMID:23649840 NCBI chr14:46,717,657...46,917,326
Ensembl chr14:46,718,760...46,917,154 		JBrowse link
G Arf1 ARF GTPase 1 increases expression ISO Vincristine results in increased expression of ARF1 mRNA CTD PMID:23649840 NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434 		JBrowse link
G Arhgap15 Rho GTPase activating protein 15 increases expression ISO Vincristine results in increased expression of ARHGAP15 mRNA CTD PMID:23649840 NCBI chr 3:27,989,368...28,592,722
Ensembl chr 3:27,989,633...28,600,265 		JBrowse link
G Arhgap18 Rho GTPase activating protein 18 decreases expression ISO Vincristine results in decreased expression of ARHGAP18 mRNA CTD PMID:23649840 NCBI chr 1:18,403,531...18,637,306
Ensembl chr 1:18,403,537...18,637,256 		JBrowse link
G Arhgap5 Rho GTPase activating protein 5 decreases expression ISO Vincristine results in decreased expression of ARHGAP5 mRNA CTD PMID:23649840 NCBI chr 6:69,975,904...70,039,299
Ensembl chr 6:69,976,214...70,037,660 		JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression ISO Vincristine results in increased expression of ARHGEF6 mRNA CTD PMID:23649840 NCBI chr  X:135,145,447...135,264,636
Ensembl chr  X:135,146,786...135,275,304 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 increases expression ISO Vincristine results in increased expression of ARHGEF7 mRNA CTD PMID:23649840 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697 		JBrowse link
G Arid2 AT-rich interaction domain 2 increases expression ISO Vincristine results in increased expression of ARID2 mRNA CTD PMID:23649840 NCBI chr 7:127,447,192...127,565,987
Ensembl chr 7:127,447,278...127,563,512 		JBrowse link
G Arid4b AT-rich interaction domain 4B increases expression ISO Vincristine results in increased expression of ARID4B mRNA CTD PMID:23649840 NCBI chr17:51,138,419...51,262,894
Ensembl chr17:51,138,535...51,262,906 		JBrowse link
G Arl5a ARF like GTPase 5A decreases expression ISO Vincristine results in decreased expression of ARL5A mRNA CTD PMID:23649840 NCBI chr 3:36,878,461...36,903,362
Ensembl chr 3:36,880,712...36,903,211 		JBrowse link
G Arl5b ARF like GTPase 5B increases expression ISO Vincristine results in increased expression of ARL5B mRNA CTD PMID:23649840 NCBI chr17:77,955,864...77,979,895
Ensembl chr17:77,955,818...77,979,854 		JBrowse link
G Arl6ip1 ARL6 interacting reticulophagy regulator 1 decreases expression ISO Vincristine results in decreased expression of ARL6IP1 mRNA CTD PMID:23649840 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994 		JBrowse link
G Armc8 armadillo repeat containing 8 decreases expression ISO Vincristine results in decreased expression of ARMC8 mRNA CTD PMID:23649840 NCBI chr 8:100,036,946...100,131,544
Ensembl chr 8:100,036,946...100,131,520 		JBrowse link
G Aspm assembly factor for spindle microtubules increases expression ISO Vincristine results in increased expression of ASPM mRNA CTD PMID:17374387 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755 		JBrowse link
G Asxl1 ASXL transcriptional regulator 1 increases expression ISO Vincristine results in increased expression of ASXL1 mRNA CTD PMID:23649840 NCBI chr 3:141,814,012...141,881,526
Ensembl chr 3:141,813,433...141,881,538 		JBrowse link
G Atad2 ATPase family, AAA domain containing 2 decreases expression ISO Vincristine results in decreased expression of ATAD2 mRNA CTD PMID:23649840 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Vincristine results in increased expression of ATF3 mRNA CTD PMID:23649840 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO Vincristine results in increased expression of ATF5 mRNA CTD PMID:23649840 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Atf6 activating transcription factor 6 multiple interactions
increases expression		 EXP Quercetin inhibits the reaction [Vincristine results in increased expression of ATF6 mRNA] CTD PMID:33038355 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression ISO Vincristine results in increased expression of ATP2B4 mRNA CTD PMID:23649840 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression ISO Vincristine results in decreased expression of ATP5F1C mRNA CTD PMID:23649840 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Atp6v0e1 ATPase H+ transporting V0 subunit e1 increases expression ISO Vincristine results in increased expression of ATP6V0E1 mRNA CTD PMID:23649840 NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434 		JBrowse link
G Atp7a ATPase copper transporting alpha decreases response to substance ISO ATP7A protein results in decreased susceptibility to Vincristine CTD PMID:17510416 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 decreases expression ISO Vincristine results in decreased expression of ATP8A1 mRNA CTD PMID:23649840 NCBI chr14:40,315,013...40,557,572
Ensembl chr14:40,315,049...40,554,611 		JBrowse link
G Aurka aurora kinase A increases response to substance
increases expression		 ISO AURKA gene SNP results in increased susceptibility to Vincristine
Vincristine results in increased expression of AURKA mRNA		 CTD PMID:17374387 PMID:20864405 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Aurkb aurora kinase B decreases expression ISO Vincristine results in decreased expression of AURKB mRNA CTD PMID:23649840 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837 		JBrowse link
G Avp arginine vasopressin increases expression ISO Vincristine results in increased expression of AVP protein CTD PMID:4356234 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G B3galt6 Beta-1,3-galactosyltransferase 6 decreases expression ISO Vincristine results in decreased expression of B3GALT6 mRNA CTD PMID:23649840 NCBI chr 5:166,584,202...166,586,338
Ensembl chr 5:166,584,202...166,586,338 		JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 increases expression ISO Vincristine results in increased expression of B3GNT5 mRNA CTD PMID:23649840 NCBI chr11:81,141,102...81,153,206
Ensembl chr11:81,140,599...81,156,166 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 affects response to substance ISO BAK1 protein affects the susceptibility to Vincristine CTD PMID:22178383 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bambi BMP and activin membrane-bound inhibitor increases expression ISO Vincristine results in increased expression of BAMBI mRNA CTD PMID:23649840 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 decreases expression ISO Vincristine results in decreased expression of BARD1 mRNA CTD PMID:23649840 NCBI chr 9:72,616,070...72,694,553
Ensembl chr 9:72,623,155...72,694,265 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression ISO Vincristine results in increased expression of BASP1 mRNA CTD PMID:23649840 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Batf basic leucine zipper ATF-like transcription factor increases expression ISO Vincristine results in increased expression of BATF mRNA CTD PMID:23649840 NCBI chr 6:105,353,715...105,376,051
Ensembl chr 6:105,353,715...105,376,051 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
increases expression
affects response to substance		 ISO
EXP		 Vincristine results in decreased expression of BAX mRNA
KN 93 inhibits the reaction [Vincristine results in increased expression of BAX mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of BAX protein]
Vincristine results in increased expression of BAX mRNA; Vincristine results in increased expression of BAX protein
Quercetin inhibits the reaction [Vincristine results in increased expression of BAX mRNA]
BAX protein affects the susceptibility to Vincristine
[Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BAX protein; Vincristine results in increased cleavage of and results in increased expression of BAX protein		 CTD PMID:9815696 PMID:15131059 PMID:16001973 PMID:22178383 PMID:33038355 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcat1 branched chain amino acid transaminase 1 increases expression ISO Vincristine results in increased expression of BCAT1 mRNA CTD PMID:23649840 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases response to substance
multiple interactions
decreases expression
increases phosphorylation		 ISO
EXP		 BCL2 protein results in decreased susceptibility to Vincristine
KN 93 inhibits the reaction [Vincristine results in decreased expression of BCL2 mRNA]; KN 93 inhibits the reaction [Vincristine results in decreased expression of BCL2 protein]
Vincristine results in decreased expression of BCL2 mRNA; Vincristine results in decreased expression of BCL2 protein
Quercetin inhibits the reaction [Vincristine results in decreased expression of BCL2 mRNA]
Vincristine results in increased phosphorylation of BCL2 protein
[Doxorubicin co-treated with Dexamethasone co-treated with Vincristine co-treated with Cytarabine co-treated with Mercaptopurine co-treated with Methotrexate co-treated with Cyclophosphamide co-treated with Enzymes and Coenzymes] results in increased expression of BCL2 protein; [Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of BCL2 protein; [MIR497 results in decreased expression of BCL2 protein] which results in increased susceptibility to Vincristine; TYMP inhibits the reaction [Vincristine results in increased phosphorylation of BCL2 protein]		 CTD PMID:9815696 PMID:15907805 PMID:20162574 PMID:21182165 PMID:21258880 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO Vincristine results in increased expression of BCL2A1 mRNA CTD PMID:23649840 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression
affects response to substance		 ISO Vincristine results in increased expression of BCL2L1 mRNA
BCL2L1 protein affects the susceptibility to Vincristine		 CTD PMID:22178383 PMID:23649840 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO Vincristine results in decreased expression of BCLAF1 mRNA CTD PMID:23649840 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Bcor BCL6 co-repressor increases expression ISO Vincristine results in increased expression of BCOR mRNA CTD PMID:23649840 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613 		JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions EXP [HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Vincristine CTD PMID:17989505 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Bdkrb2 bradykinin receptor B2 multiple interactions EXP [icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Vincristine CTD PMID:17989505 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 increases expression ISO Vincristine results in increased expression of BIRC2 mRNA CTD PMID:23649840 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression ISO Vincristine results in increased expression of BIRC3 mRNA CTD PMID:23649840 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Vincristine results in decreased expression of BLM mRNA CTD PMID:23649840 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312 		JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO Vincristine results in increased expression of BMP2 mRNA CTD PMID:23649840 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression
multiple interactions		 ISO Vincristine results in decreased expression of BNIP3 mRNA
Vincristine affects the reaction [Valproic Acid affects the localization of BNIP3 protein]		 CTD PMID:23649840 PMID:25446377 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression ISO Vincristine results in decreased expression of BNIP3L mRNA CTD PMID:23649840 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Borcs7 BLOC-1 related complex subunit 7 increases expression ISO Vincristine results in increased expression of BORCS7 mRNA CTD PMID:23649840 NCBI chr 1:245,564,347...245,578,182
Ensembl chr 1:245,564,369...245,579,343 		JBrowse link
G Brip1 BRCA1 interacting DNA helicase 1 decreases expression ISO Vincristine results in decreased expression of BRIP1 mRNA CTD PMID:23649840 NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324 		JBrowse link
G Brwd1 bromodomain and WD repeat domain containing 1 decreases expression ISO Vincristine results in decreased expression of BRWD1 mRNA CTD PMID:23649840 NCBI chr11:35,286,364...35,378,768
Ensembl chr11:35,288,313...35,378,768 		JBrowse link
G Btg1 BTG anti-proliferation factor 1 increases expression ISO Vincristine results in increased expression of BTG1 mRNA CTD PMID:23649840 NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Vincristine results in increased expression of BTG2 mRNA CTD PMID:23649840 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btg4 BTG anti-proliferation factor 4 increases expression ISO Vincristine results in increased expression of BTG4 mRNA CTD PMID:23649840 NCBI chr 8:51,410,774...51,425,802
Ensembl chr 8:51,422,061...51,425,796 		JBrowse link
G Bub3 BUB3 mitotic checkpoint protein decreases expression ISO Vincristine results in decreased expression of BUB3 mRNA CTD PMID:23649840 NCBI chr 1:186,330,358...186,340,969
Ensembl chr 1:186,327,931...186,395,036 		JBrowse link
G C13h1orf74 similar to human chromosome 1 open reading frame 74 decreases expression ISO Vincristine results in decreased expression of C1ORF74 mRNA CTD PMID:23649840 NCBI chr13:104,692,769...104,695,368
Ensembl chr13:104,692,824...104,695,470 		JBrowse link
G C1galt1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 decreases expression ISO Vincristine results in decreased expression of C1GALT1 mRNA CTD PMID:23649840 NCBI chr 4:35,930,981...35,966,100
Ensembl chr 4:35,928,104...35,961,831 		JBrowse link
G C7h12orf54 similar to human chromosome 12 open reading frame 54 increases expression ISO Vincristine results in increased expression of C12ORF54 mRNA CTD PMID:23649840 NCBI chr 7:129,529,811...129,548,676 JBrowse link
G C8h15orf39 similar to human chromosome 15 open reading frame 39 decreases expression ISO Vincristine results in decreased expression of C15ORF39 mRNA CTD PMID:23649840 NCBI chr 8:57,646,324...57,655,896
Ensembl chr 8:57,645,756...57,655,941 		JBrowse link
G Cables2 Cdk5 and Abl enzyme substrate 2 decreases expression ISO Vincristine results in decreased expression of CABLES2 mRNA CTD PMID:23649840 NCBI chr 3:167,347,527...167,362,274
Ensembl chr 3:167,347,461...167,362,279 		JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H increases expression
multiple interactions		 ISO Vincristine results in increased expression of CACNA1H mRNA; Vincristine results in increased expression of CACNA1H protein
Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of CACNA1H mRNA]; Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]; KN 62 inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]; KN 93 inhibits the reaction [Vincristine results in increased expression of CACNA1H mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]; zinc chloride inhibits the reaction [Vincristine results in increased expression of CACNA1H protein]		 CTD PMID:34286406 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376 		JBrowse link
G Cacnb2 calcium voltage-gated channel auxiliary subunit beta 2 increases expression ISO Vincristine results in increased expression of CACNB2 mRNA CTD PMID:23649840 NCBI chr17:77,564,630...77,910,000
Ensembl chr17:77,564,460...77,909,106 		JBrowse link
G Cald1 caldesmon 1 increases expression ISO Vincristine results in increased expression of CALD1 mRNA CTD PMID:23649840 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Calm2 calmodulin 2 decreases expression ISO Vincristine results in decreased expression of CALM2 mRNA CTD PMID:23649840 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Calu calumenin increases expression ISO Vincristine results in increased expression of CALU mRNA CTD PMID:23649840 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression ISO Vincristine results in decreased expression of CAMK2D mRNA CTD PMID:23649840 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 increases response to substance ISO CAMKK1 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498 		JBrowse link
G Capg capping actin protein, gelsolin like increases expression ISO Vincristine results in increased expression of CAPG mRNA CTD PMID:23649840 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 decreases expression ISO Vincristine results in decreased expression of CARHSP1 mRNA CTD PMID:23649840 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019 		JBrowse link
G Casp1 caspase 1 increases expression ISO Vincristine results in increased expression of CASP1 mRNA CTD PMID:23649840 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression		 EXP
ISO		 Vincristine results in increased cleavage of CASP3 protein
KN 93 inhibits the reaction [Vincristine results in increased cleavage of CASP3 protein]
coenzyme Q10 inhibits the reaction [Vincristine results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [Vincristine results in increased expression of CASP3 mRNA]; Quercetin inhibits the reaction [Vincristine results in increased expression of CASP3 protein]; Sumatriptan inhibits the reaction [Vincristine results in increased expression of CASP3 mRNA]; Sumatriptan inhibits the reaction [Vincristine results in increased expression of CASP3 protein]
Vincristine results in increased expression of CASP3 mRNA; Vincristine results in increased expression of CASP3 protein		 CTD PMID:20624997 PMID:29958920 PMID:33038355 PMID:34286406 PMID:34939713 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 increases expression ISO Vincristine results in increased expression of CASP6 mRNA CTD PMID:16001973 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp8 caspase 8 increases expression
increases response to substance
multiple interactions		 ISO Vincristine results in increased expression of CASP8 mRNA
CASP8 protein results in increased susceptibility to Vincristine
Vincristine results in increased expression of and results in increased cleavage of CASP8 protein		 CTD PMID:16001973 PMID:22010212 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase affects response to substance
decreases activity
decreases expression
multiple interactions		 ISO
EXP		 CAT protein affects the susceptibility to Vincristine
Vincristine results in decreased activity of CAT protein
Vincristine results in decreased expression of CAT protein
Quercetin inhibits the reaction [Vincristine results in decreased activity of CAT protein]; tetrahydrocurcumin inhibits the reaction [Vincristine results in decreased expression of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased activity of CAT protein]; Vincristine inhibits the reaction [Isoproterenol results in decreased expression of CAT protein]		 CTD PMID:11178967 PMID:24201307 PMID:25537132 PMID:26102012 PMID:36808657 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbx3 chromobox 3 decreases expression ISO Vincristine results in decreased expression of CBX3 mRNA CTD PMID:23649840 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283 		JBrowse link
G Cbx5 chromobox 5 decreases expression ISO Vincristine results in decreased expression of CBX5 mRNA CTD PMID:23649840 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 decreases expression ISO Vincristine results in decreased expression of CCAR1 mRNA CTD PMID:23649840 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526 		JBrowse link
G Ccdc12 coiled-coil domain containing 12 decreases expression ISO Vincristine results in decreased expression of CCDC12 mRNA CTD PMID:23649840 NCBI chr 8:110,635,276...110,686,417
Ensembl chr 8:110,635,710...110,686,417 		JBrowse link
G Ccdc186 coiled-coil domain containing 186 decreases expression ISO Vincristine results in decreased expression of CCDC186 mRNA CTD PMID:23649840 NCBI chr 1:255,831,663...255,871,954
Ensembl chr 1:255,839,595...255,871,935 		JBrowse link
G Ccdc198 coiled-coil domain containing 198 decreases expression ISO Vincristine results in decreased expression of CCDC198 mRNA CTD PMID:23649840 NCBI chr15:22,500,181...22,527,011
Ensembl chr15:22,502,687...22,526,992 		JBrowse link
G Ccdc32 coiled-coil domain containing 32 decreases expression ISO Vincristine results in decreased expression of CCDC32 mRNA CTD PMID:23649840 NCBI chr 3:105,998,429...106,010,985
Ensembl chr 3:105,998,430...106,010,975 		JBrowse link
G Ccdc82 coiled-coil domain containing 82 increases expression ISO Vincristine results in increased expression of CCDC82 mRNA CTD PMID:23649840 NCBI chr 8:10,227,727...10,265,963
Ensembl chr 8:10,228,430...10,265,963 		JBrowse link
G Cchcr1 coiled-coil alpha-helical rod protein 1 decreases expression ISO Vincristine results in decreased expression of CCHCR1 mRNA CTD PMID:23649840 NCBI chr20:3,205,675...3,218,437
Ensembl chr20:3,205,676...3,218,308 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 increases expression ISO Vincristine results in increased expression of CCL1 mRNA CTD PMID:23649840 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO
EXP		 Vincristine results in increased expression of CCL2 mRNA CTD PMID:20624997 PMID:23649840 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Vincristine results in increased expression of CCL20 mRNA CTD PMID:23649840 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 increases expression ISO Vincristine results in increased expression of CCL22 mRNA CTD PMID:23649840 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO Vincristine results in increased expression of CCL4 mRNA CTD PMID:23649840 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO Vincristine results in increased expression of CCL5 mRNA CTD PMID:23649840 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases response to substance ISO CCN2 mRNA results in decreased susceptibility to Vincristine CTD PMID:24154679 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnb1 cyclin B1 affects response to substance
increases expression		 ISO CCNB1 protein affects the susceptibility to Vincristine
Vincristine results in increased expression of CCNB1 mRNA		 CTD PMID:22178383 PMID:23649840 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Vincristine results in increased expression of CCNB2 mRNA CTD PMID:23649840 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Vincristine results in decreased expression of CCNE1 mRNA CTD PMID:23649840 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccne2 cyclin E2 decreases expression ISO Vincristine results in decreased expression of CCNE2 mRNA CTD PMID:23649840 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632 		JBrowse link
G Ccnl1 cyclin L1 decreases expression ISO Vincristine results in decreased expression of CCNL1 mRNA CTD PMID:23649840 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368 		JBrowse link
G Cd109 CD109 molecule increases expression ISO Vincristine results in increased expression of CD109 mRNA CTD PMID:23649840 NCBI chr 8:79,454,480...79,569,195
Ensembl chr 8:79,454,480...79,569,194 		JBrowse link
G Cd14 CD14 molecule increases expression EXP Vincristine results in increased expression of CD14 mRNA CTD PMID:20624997 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd200 Cd200 molecule increases expression ISO Vincristine results in increased expression of CD200 mRNA CTD PMID:23649840 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648 		JBrowse link
G Cd274 CD274 molecule increases expression ISO Vincristine results in increased expression of CD274 mRNA CTD PMID:23649840 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd36 CD36 molecule increases expression EXP Vincristine results in increased expression of CD36 mRNA CTD PMID:20624997 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd40 CD40 molecule increases expression ISO Vincristine results in increased expression of CD40 mRNA CTD PMID:23649840 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd44 CD44 molecule increases expression ISO Vincristine results in increased expression of CD44 mRNA CTD PMID:23649840 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd48 Cd48 molecule increases expression ISO Vincristine results in increased expression of CD48 mRNA CTD PMID:23649840 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) increases expression ISO Vincristine results in increased expression of CD55 mRNA CTD PMID:23649840 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd69 Cd69 molecule increases expression ISO Vincristine results in increased expression of CD69 mRNA CTD PMID:23649840 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542 		JBrowse link
G Cd80 Cd80 molecule increases expression ISO Vincristine results in increased expression of CD80 mRNA CTD PMID:23649840 NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030 		JBrowse link
G Cd83 CD83 molecule increases expression ISO Vincristine results in increased expression of CD83 mRNA CTD PMID:23649840 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Cd86 CD86 molecule increases expression ISO Vincristine results in increased expression of CD86 mRNA CTD PMID:23649840 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression ISO Vincristine results in increased expression of CDC42EP3 mRNA CTD PMID:23649840 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721 		JBrowse link
G Cdc42ep4 CDC42 effector protein 4 increases expression ISO Vincristine results in increased expression of CDC42EP4 mRNA CTD PMID:23649840 NCBI chr10:98,772,613...98,797,924
Ensembl chr10:98,772,495...98,797,695 		JBrowse link
G Cdc42se1 CDC42 small effector 1 increases expression ISO Vincristine results in increased expression of CDC42SE1 mRNA CTD PMID:23649840 NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028 		JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Vincristine results in decreased expression of CDC6 mRNA CTD PMID:23649840 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdca3 cell division cycle associated 3 decreases expression ISO Vincristine results in decreased expression of CDCA3 mRNA CTD PMID:23649840 NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799 		JBrowse link
G Cdca7 cell division cycle associated 7 decreases expression ISO Vincristine results in decreased expression of CDCA7 mRNA CTD PMID:23649840 NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353 		JBrowse link
G Cdh1 cadherin 1 increases expression ISO Vincristine results in increased expression of CDH1 mRNA CTD PMID:23649840 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Vincristine results in decreased expression of CDK1 mRNA CTD PMID:23649840 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk10 cyclin-dependent kinase 10 decreases expression ISO Vincristine results in decreased expression of CDK10 mRNA CTD PMID:23649840 NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078 		JBrowse link
G Cdk19 cyclin-dependent kinase 19 decreases expression ISO Vincristine results in decreased expression of CDK19 mRNA CTD PMID:23649840 NCBI chr20:43,770,409...43,910,629
Ensembl chr20:43,770,409...43,910,628 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression ISO Vincristine results in decreased expression of CDK2 mRNA CTD PMID:23649840 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions		 EXP
ISO		 Vincristine results in increased expression of CDKN1A mRNA
[XL019 compound co-treated with Vincristine] results in increased expression of CDKN1A protein; Resveratrol inhibits the reaction [Vincristine results in increased expression of CDKN1A mRNA]		 CTD PMID:20624997 PMID:23649840 PMID:26055805 PMID:29187454 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases response to substance ISO CDKN2A protein results in increased susceptibility to Vincristine CTD PMID:16786135 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO Vincristine results in decreased expression of CDKN2C mRNA CTD PMID:23649840 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO Vincristine results in increased expression of CEACAM1 mRNA CTD PMID:23649840 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Vincristine results in increased expression of CEBPB mRNA CTD PMID:16001973 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Celf1 CUGBP, Elav-like family member 1 decreases expression ISO Vincristine results in decreased expression of CELF1 mRNA CTD PMID:23649840 NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426 		JBrowse link
G Cenpc centromere protein C decreases expression ISO Vincristine results in decreased expression of CENPC1 mRNA CTD PMID:23649840 NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476 		JBrowse link
G Cenpf centromere protein F decreases expression ISO Vincristine results in decreased expression of CENPF mRNA CTD PMID:23649840 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669 		JBrowse link
G Cenpi centromere protein I decreases expression ISO Vincristine results in decreased expression of CENPI mRNA CTD PMID:23649840 NCBI chr  X:97,515,919...97,567,671
Ensembl chr  X:97,515,972...97,567,657 		JBrowse link
G Cenpu centromere protein U decreases expression ISO Vincristine results in decreased expression of CENPU mRNA CTD PMID:23649840 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823 		JBrowse link
G Cep135 centrosomal protein 135 increases expression ISO Vincristine results in increased expression of CEP135 mRNA CTD PMID:23649840 NCBI chr14:31,530,538...31,595,812
Ensembl chr14:31,531,482...31,595,772 		JBrowse link
G Ces5a carboxylesterase 5A increases expression ISO Vincristine results in increased expression of CES5A mRNA CTD PMID:23649840 NCBI chr19:11,469,431...11,499,007
Ensembl chr19:11,469,469...11,499,006 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Vincristine results in increased expression of CFLAR mRNA CTD PMID:23649840 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Chd1l chromodomain helicase DNA binding protein 1-like increases expression ISO Vincristine results in increased expression of CHD1L mRNA CTD PMID:23649840 NCBI chr 2:185,138,526...185,217,498
Ensembl chr 2:185,139,308...185,217,595 		JBrowse link
G Chek2 checkpoint kinase 2 decreases expression ISO Vincristine results in decreased expression of CHEK2 mRNA CTD PMID:23649840 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chm CHM Rab escort protein increases expression ISO Vincristine results in increased expression of CHM mRNA CTD PMID:23649840 NCBI chr  X:78,203,200...78,361,996
Ensembl chr  X:78,203,204...78,361,943 		JBrowse link
G Chml CHM like Rab escort protein decreases expression ISO Vincristine results in decreased expression of CHML mRNA CTD PMID:23649840 NCBI chr13:87,609,647...87,619,868
Ensembl chr13:87,589,298...87,619,862 		JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 decreases expression ISO Vincristine results in decreased expression of CHTF18 mRNA CTD PMID:23649840 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050 		JBrowse link
G Ciapin1 cytokine induced apoptosis inhibitor 1 decreases response to substance ISO CIAPIN1 protein results in decreased susceptibility to Vincristine CTD PMID:18389626 NCBI chr19:10,179,963...10,195,511
Ensembl chr19:10,180,100...10,195,503 		JBrowse link
G Cirbp cold inducible RNA binding protein decreases expression ISO Vincristine results in decreased expression of CIRBP mRNA CTD PMID:23649840 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 increases expression ISO Vincristine results in increased expression of CLASP2 mRNA CTD PMID:23649840 NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Clec2d C-type lectin domain family 2, member D decreases expression ISO Vincristine results in decreased expression of CLEC2D mRNA CTD PMID:23649840 NCBI chr 4:162,216,052...162,239,530
Ensembl chr 4:162,216,572...162,239,527 		JBrowse link
G Clic2 chloride intracellular channel 2 increases expression ISO Vincristine results in increased expression of CLIC2 mRNA CTD PMID:23649840 NCBI chr20:149,337...164,375
Ensembl chr20:148,907...164,355 		JBrowse link
G Clspn claspin decreases expression ISO Vincristine results in decreased expression of CLSPN mRNA CTD PMID:23649840 NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034 		JBrowse link
G Cnksr2 connector enhancer of kinase suppressor of Ras 2 decreases expression ISO Vincristine results in decreased expression of CNKSR2 mRNA CTD PMID:23649840 NCBI chr  X:36,908,135...37,148,337
Ensembl chr  X:36,907,850...37,150,555 		JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 decreases expression ISO Vincristine results in decreased expression of CNOT3 mRNA CTD PMID:23649840 NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167 		JBrowse link
G Cnot6l CCR4-NOT transcription complex, subunit 6-like decreases expression ISO Vincristine results in decreased expression of CNOT6L mRNA CTD PMID:23649840 NCBI chr14:13,410,499...13,502,511
Ensembl chr14:13,411,281...13,498,203 		JBrowse link
G Cntln centlein decreases expression ISO Vincristine results in decreased expression of CNTLN mRNA CTD PMID:23649840 NCBI chr 5:99,295,865...99,576,402
Ensembl chr 5:99,296,000...99,576,396 		JBrowse link
G Col15a1 collagen type XV alpha 1 chain decreases response to substance ISO COL15A1 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 5:61,501,963...61,607,591
Ensembl chr 5:61,501,963...61,607,591 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases response to substance ISO COL1A2 mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases response to substance ISO COL3A1 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col5a2 collagen type V alpha 2 chain decreases response to substance ISO COL5A2 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Comtd1 catechol-O-methyltransferase domain containing 1 decreases expression ISO Vincristine results in decreased expression of COMTD1 mRNA CTD PMID:23649840 NCBI chr15:2,459,783...2,462,895
Ensembl chr15:2,459,783...2,462,895 		JBrowse link
G Cp ceruloplasmin increases expression EXP Vincristine results in increased expression of CP mRNA CTD PMID:20624997 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpeb2 cytoplasmic polyadenylation element binding protein 2 increases expression ISO Vincristine results in increased expression of CPEB2 mRNA CTD PMID:23649840 NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743 		JBrowse link
G Cpne3 copine 3 decreases expression ISO Vincristine results in decreased expression of CPNE3 mRNA CTD PMID:23649840 NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934 		JBrowse link
G Cpsf6 cleavage and polyadenylation specific factor 6 decreases expression ISO Vincristine results in decreased expression of CPSF6 mRNA CTD PMID:23649840 NCBI chr 7:52,956,589...53,001,783
Ensembl chr 7:52,956,589...52,988,122 		JBrowse link
G Crebbp CREB binding protein increases expression ISO Vincristine results in increased expression of CREBBP mRNA CTD PMID:23649840 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO Vincristine results in increased expression of CREBRF mRNA CTD PMID:23649840 NCBI chr10:16,399,170...16,479,650
Ensembl chr10:16,404,596...16,461,999 		JBrowse link
G Crebzf CREB/ATF bZIP transcription factor decreases expression ISO Vincristine results in decreased expression of CREBZF mRNA CTD PMID:23649840 NCBI chr 1:144,416,864...144,423,540
Ensembl chr 1:144,417,446...144,428,553 		JBrowse link
G Crtap cartilage associated protein decreases expression ISO Vincristine results in decreased expression of CRTAP mRNA CTD PMID:23649840 NCBI chr 8:114,047,929...114,067,636
Ensembl chr 8:114,047,933...114,067,631 		JBrowse link
G Crtc3 CREB regulated transcription coactivator 3 increases expression ISO Vincristine results in increased expression of CRTC3 mRNA CTD PMID:23649840 NCBI chr 1:134,552,830...134,655,929
Ensembl chr 1:134,554,696...134,655,500 		JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression ISO Vincristine results in decreased expression of CSAD mRNA CTD PMID:23649840 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Vincristine results in increased expression of CSF2 mRNA CTD PMID:23649840 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 increases expression ISO Vincristine results in increased expression of CSNK1A1 mRNA CTD PMID:23649840 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 increases expression ISO Vincristine results in increased expression of CSNK1G1 mRNA CTD PMID:23649840 NCBI chr 8:66,439,760...66,577,247
Ensembl chr 8:66,439,864...66,572,826 		JBrowse link
G Csta cystatin A increases expression ISO Vincristine results in increased expression of CSTA mRNA CTD PMID:23649840 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488 		JBrowse link
G Cstf1 cleavage stimulation factor subunit 1 decreases expression ISO Vincristine results in decreased expression of CSTF1 mRNA CTD PMID:23649840 NCBI chr 3:161,144,522...161,156,294
Ensembl chr 3:161,144,548...161,156,300 		JBrowse link
G Ctc1 CST telomere replication complex component 1 decreases expression ISO Vincristine results in decreased expression of CTC1 mRNA CTD PMID:23649840 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298 		JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO Vincristine results in increased expression of CTH mRNA CTD PMID:23649840 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctnnal1 catenin alpha-like 1 decreases expression ISO Vincristine results in decreased expression of CTNNAL1 mRNA CTD PMID:23649840 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression
decreases response to substance		 ISO Vincristine results in increased expression of CTNNB1 mRNA
CTNNB1 results in decreased susceptibility to Vincristine		 CTD PMID:22000491 PMID:23649840 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cul4a cullin 4A increases expression ISO Vincristine results in increased expression of CUL4A mRNA CTD PMID:23649840 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Vincristine results in increased expression of CXCL10 mRNA CTD PMID:23649840 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Vincristine results in increased expression of CXCL11 mRNA CTD PMID:23649840 NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression
multiple interactions		 ISO Vincristine results in increased expression of CXCL12 mRNA
KN 93 inhibits the reaction [Vincristine results in increased expression of CXCL12 mRNA]		 CTD PMID:34286406 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Vincristine results in increased expression of CXCL9 mRNA CTD PMID:23649840 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase increases expression ISO Vincristine results in increased expression of CYLD mRNA CTD PMID:23649840 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases response to substance ISO CYP2C8 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 protein results in increased metabolism of Vincristine CTD PMID:19346885 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions
increases metabolic processing		 ISO [CYP3A5 gene polymorphism results in increased activity of CYP3A5 protein] which results in increased metabolism of Vincristine
CYP3A5 protein results in increased metabolism of Vincristine		 CTD PMID:21225912 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO Vincristine results in increased expression of CYP4F3 mRNA CTD PMID:23649840 NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940 		JBrowse link
G Cyp4v3 cytochrome P450, family 4, subfamily v, polypeptide 3 decreases expression ISO Vincristine results in decreased expression of CYP4V2 mRNA CTD PMID:23649840 NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 decreases expression ISO Vincristine results in decreased expression of CYSLTR1 mRNA CTD PMID:23649840 NCBI chr  X:71,661,421...71,690,012
Ensembl chr  X:71,663,821...71,690,121 		JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 increases expression ISO Vincristine results in increased expression of DAAM1 mRNA CTD PMID:23649840 NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114 		JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 increases expression ISO Vincristine results in increased expression of DCAF8 mRNA CTD PMID:23649840 NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726 		JBrowse link
G Dcn decorin decreases response to substance ISO DCN mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Dcun1d1 defective in cullin neddylation 1 domain containing 1 increases expression ISO Vincristine results in increased expression of DCUN1D1 mRNA CTD PMID:23649840 NCBI chr 2:118,721,275...118,772,606
Ensembl chr 2:118,721,822...118,772,602 		JBrowse link
G Dcun1d4 defective in cullin neddylation 1 domain containing 4 decreases expression ISO Vincristine results in decreased expression of DCUN1D4 mRNA CTD PMID:23649840 NCBI chr14:34,652,723...34,733,122
Ensembl chr14:34,652,723...34,733,207 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Vincristine results in increased expression of DDIT3 mRNA CTD PMID:23649840 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddx50 DExD-box helicase 50 increases expression ISO Vincristine results in increased expression of DDX50 mRNA CTD PMID:23649840 NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152 		JBrowse link
G Ddx52 DExD-box helicase 52 increases expression ISO Vincristine results in increased expression of DDX52 mRNA CTD PMID:23649840 NCBI chr10:68,824,594...68,847,400
Ensembl chr10:68,824,645...68,848,266 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 increases expression ISO Vincristine results in increased expression of DDX60 mRNA CTD PMID:23649840 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dennd5a DENN domain containing 5A increases expression ISO Vincristine results in increased expression of DENND5A mRNA CTD PMID:23649840 NCBI chr 1:163,928,183...163,994,207
Ensembl chr 1:163,928,183...163,994,316 		JBrowse link
G Dgcr8 DGCR8 microprocessor complex subunit decreases expression ISO Vincristine results in decreased expression of DGCR8 mRNA CTD PMID:23649840 NCBI chr11:82,704,673...82,737,251
Ensembl chr11:82,704,729...82,737,242 		JBrowse link
G Dhfr dihydrofolate reductase decreases expression ISO Vincristine results in decreased expression of DHFR mRNA CTD PMID:23649840 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Dhrs11 dehydrogenase/reductase 11 decreases expression ISO Vincristine results in decreased expression of DHRS11 mRNA CTD PMID:23649840 NCBI chr10:69,698,214...69,708,294
Ensembl chr10:69,698,214...69,708,295 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO Vincristine results in increased expression of DHRS2 mRNA CTD PMID:23649840 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dhrs7 dehydrogenase/reductase 7 increases expression ISO Vincristine results in increased expression of DHRS7 mRNA CTD PMID:23649840 NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein decreases expression ISO Vincristine results in decreased expression of DIABLO mRNA CTD PMID:23649840 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dido1 death inducer-obliterator 1 decreases expression ISO Vincristine results in decreased expression of DIDO1 mRNA CTD PMID:23649840 NCBI chr 3:167,772,535...167,825,894
Ensembl chr 3:167,772,770...167,817,218 		JBrowse link
G Dip2a disco-interacting protein 2 homolog A increases expression ISO Vincristine results in increased expression of DIP2A mRNA CTD PMID:23649840 NCBI chr20:12,284,566...12,371,068
Ensembl chr20:12,284,654...12,370,217 		JBrowse link
G Dmd dystrophin increases expression ISO Vincristine results in increased expression of DMD mRNA CTD PMID:23649840 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases expression ISO Vincristine results in decreased expression of DNAJB1 mRNA CTD PMID:23649840 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dnajc7 DnaJ heat shock protein family (Hsp40) member C7 increases expression ISO Vincristine results in increased expression of DNAJC7 mRNA CTD PMID:23649840 NCBI chr10:85,518,637...85,555,079
Ensembl chr10:85,518,621...85,555,575 		JBrowse link
G Dnase1l3 deoxyribonuclease 1L3 decreases expression ISO Vincristine results in decreased expression of DNASE1L3 mRNA CTD PMID:23649840 NCBI chr15:16,922,335...16,948,322
Ensembl chr15:16,922,335...16,948,317 		JBrowse link
G Dnmbp dynamin binding protein decreases expression ISO Vincristine results in decreased expression of DNMBP mRNA CTD PMID:23649840 NCBI chr 1:242,736,189...242,829,431
Ensembl chr 1:242,736,189...242,802,604 		JBrowse link
G Dock4 dedicator of cytokinesis 4 increases expression ISO Vincristine results in increased expression of DOCK4 mRNA CTD PMID:23649840 NCBI chr 6:57,512,929...57,902,597
Ensembl chr 6:57,512,908...57,901,855 		JBrowse link
G Dock8 dedicator of cytokinesis 8 decreases expression ISO Vincristine results in decreased expression of DOCK8 mRNA CTD PMID:23649840 NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474 		JBrowse link
G Dok4 docking protein 4 increases expression ISO Vincristine results in increased expression of DOK4 mRNA CTD PMID:23649840 NCBI chr19:10,146,520...10,157,187
Ensembl chr19:10,146,474...10,158,203 		JBrowse link
G Donson DNA replication fork stabilization factor DONSON decreases expression ISO Vincristine results in decreased expression of DONSON mRNA CTD PMID:23649840 NCBI chr11:30,919,834...30,933,150
Ensembl chr11:30,923,239...30,932,889 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 decreases expression ISO Vincristine results in decreased expression of DPP4 mRNA CTD PMID:23649840 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase increases response to substance ISO DPYD gene SNP results in increased susceptibility to Vincristine CTD PMID:20864405 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 increases expression ISO Vincristine results in increased expression of DRAM1 mRNA CTD PMID:23649840 NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765 		JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Vincristine results in decreased expression of DTL mRNA CTD PMID:23649840 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Vincristine results in increased expression of DUSP1 mRNA CTD PMID:23649840 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Vincristine results in increased expression of DUSP10 mRNA CTD PMID:23649840 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dusp16 dual specificity phosphatase 16 increases expression ISO Vincristine results in increased expression of DUSP16 mRNA CTD PMID:23649840 NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980 		JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO Vincristine results in increased expression of DUSP2 mRNA CTD PMID:23649840 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499 		JBrowse link
G Dusp4 dual specificity phosphatase 4 increases expression ISO Vincristine results in increased expression of DUSP4 mRNA CTD PMID:23649840 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dynlt2 dynein light chain Tctex-type 2 decreases expression ISO Vincristine results in decreased expression of DYNLT2 mRNA CTD PMID:23649840 NCBI chr 1:55,971,285...55,983,249
Ensembl chr 1:55,971,283...55,983,307 		JBrowse link
G E2f8 E2F transcription factor 8 decreases expression ISO Vincristine results in decreased expression of E2F8 mRNA CTD PMID:23649840 NCBI chr 1:98,565,717...98,584,265
Ensembl chr 1:98,565,717...98,584,098 		JBrowse link
G Ebf1 EBF transcription factor 1 increases expression ISO Vincristine results in increased expression of EBF1 mRNA CTD PMID:23649840 NCBI chr10:29,095,858...29,489,142
Ensembl chr10:29,099,933...29,487,665 		JBrowse link
G Ednrb endothelin receptor type B increases expression EXP Vincristine results in increased expression of EDNRB mRNA CTD PMID:20624997 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Efna4 ephrin A4 decreases expression ISO Vincristine results in decreased expression of EFNA4 mRNA CTD PMID:23649840 NCBI chr 2:174,748,729...174,752,979
Ensembl chr 2:174,748,724...174,752,979 		JBrowse link
G Egfl6 EGF-like-domain, multiple 6 decreases response to substance ISO EGFL6 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr  X:27,884,087...27,942,044
Ensembl chr  X:27,884,125...27,942,044 		JBrowse link
G Egr1 early growth response 1 increases expression ISO Vincristine results in increased expression of EGR1 mRNA CTD PMID:12706485 PMID:23649840 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr3 early growth response 3 increases expression ISO Vincristine results in increased expression of EGR3 mRNA CTD PMID:23649840 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Ehbp1l1 EH domain binding protein 1-like 1 decreases expression ISO Vincristine results in decreased expression of EHBP1L1 mRNA CTD PMID:23649840 NCBI chr 1:202,994,115...203,014,320
Ensembl chr 1:202,994,118...203,014,270 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 decreases expression ISO Vincristine results in decreased expression of EIF1 mRNA CTD PMID:23649840 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327 		JBrowse link
G Eif1ad eukaryotic translation initiation factor 1A domain containing decreases expression ISO Vincristine results in decreased expression of EIF1AD mRNA CTD PMID:23649840 NCBI chr 1:202,674,362...202,679,662
Ensembl chr 1:202,674,185...202,679,658 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions		 EXP Vincristine results in increased expression of EIF2AK3 mRNA
Quercetin inhibits the reaction [Vincristine results in increased expression of EIF2AK3 mRNA]		 CTD PMID:33038355 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif3b eukaryotic translation initiation factor 3, subunit B decreases expression ISO Vincristine results in decreased expression of EIF3B mRNA CTD PMID:23649840 NCBI chr12:14,196,403...14,220,865
Ensembl chr12:14,196,403...14,220,886 		JBrowse link
G Eif3m eukaryotic translation initiation factor 3, subunit M increases expression ISO Vincristine results in increased expression of EIF3M mRNA CTD PMID:23649840 NCBI chr 3:91,424,754...91,442,358
Ensembl chr 3:91,416,325...91,442,392 		JBrowse link
G Eif4a1 eukaryotic translation initiation factor 4A1 increases expression ISO Vincristine results in increased expression of EIF4A1 mRNA CTD PMID:23649840 NCBI chr10:54,384,345...54,389,855
Ensembl chr10:54,384,347...54,389,858 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO Vincristine results in decreased expression of EIF4A2 mRNA CTD PMID:23649840 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Elf3 E74 like ETS transcription factor 3 increases expression ISO Vincristine results in increased expression of ELF3 mRNA CTD PMID:23649840 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481 		JBrowse link
G Elk3 ETS transcription factor ELK3 increases expression ISO Vincristine results in increased expression of ELK3 mRNA CTD PMID:23649840 NCBI chr 7:27,768,582...27,831,088
Ensembl chr 7:27,768,599...27,804,084 		JBrowse link
G Eme2 essential meiotic structure-specific endonuclease subunit 2 decreases expression ISO Vincristine results in decreased expression of EME2 mRNA CTD PMID:23649840 NCBI chr10:13,913,216...13,915,991
Ensembl chr10:13,913,221...13,915,968 		JBrowse link
G Eml6 EMAP like 6 decreases expression ISO Vincristine results in decreased expression of EML6 mRNA CTD PMID:23649840 NCBI chr14:103,471,537...103,806,120
Ensembl chr14:103,476,372...103,805,849 		JBrowse link
G Enox1 ecto-NOX disulfide-thiol exchanger 1 increases expression ISO Vincristine results in increased expression of ENOX1 mRNA CTD PMID:23649840 NCBI chr15:52,517,833...53,079,752
Ensembl chr15:52,515,178...53,079,749 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases expression ISO Vincristine results in increased expression of ENPP2 mRNA CTD PMID:23649840 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Ensa endosulfine alpha decreases expression ISO Vincristine results in decreased expression of ENSA mRNA CTD PMID:23649840 NCBI chr 2:183,185,552...183,192,888
Ensembl chr 2:183,185,552...183,194,847 		JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression ISO Vincristine results in increased expression of ENTPD2 mRNA CTD PMID:23649840 NCBI chr 3:8,213,575...8,219,094
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Eomes eomesodermin decreases expression ISO Vincristine results in decreased expression of EOMES mRNA CTD PMID:23649840 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Epg5 ectopic P-granules 5 autophagy tethering factor increases expression ISO Vincristine results in increased expression of EPG5 mRNA CTD PMID:23649840 NCBI chr18:71,403,990...71,502,079
Ensembl chr18:71,404,010...71,501,502 		JBrowse link
G Ephb1 Eph receptor B1 decreases expression ISO Vincristine results in decreased expression of EPHB1 mRNA CTD PMID:23649840 NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839 		JBrowse link
G Ephx1 epoxide hydrolase 1 decreases expression ISO Vincristine results in decreased expression of EPHX1 mRNA CTD PMID:21382384 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Epm2aip1 EPM2A interacting protein 1 decreases expression ISO Vincristine results in decreased expression of EPM2AIP1 mRNA CTD PMID:23649840 NCBI chr 8:111,233,871...111,241,219
Ensembl chr 8:111,233,826...111,241,871 		JBrowse link
G Epor erythropoietin receptor decreases expression ISO Vincristine results in decreased expression of EPOR mRNA CTD PMID:23649840 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G Eprs1 glutamyl-prolyl-tRNA synthetase 1 increases expression EXP Vincristine results in increased expression of EPRS1 mRNA CTD PMID:20624997 NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966 		JBrowse link
G Epsti1 epithelial stromal interaction 1 increases expression ISO Vincristine results in increased expression of EPSTI1 mRNA CTD PMID:23649840 NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191 		JBrowse link
G Erich3 glutamate-rich 3 decreases expression ISO Vincristine results in decreased expression of ERICH3 mRNA CTD PMID:23649840 NCBI chr 2:243,615,777...243,717,973
Ensembl chr 2:243,615,872...243,715,317 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases expression
multiple interactions		 EXP Vincristine results in increased expression of ERN1 mRNA
Quercetin inhibits the reaction [Vincristine results in increased expression of ERN1 mRNA]		 CTD PMID:33038355 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression ISO Vincristine results in decreased expression of ESCO2 mRNA CTD PMID:23649840 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306 		JBrowse link
G Esd esterase D decreases expression ISO Vincristine results in decreased expression of ESD mRNA CTD PMID:23649840 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144 		JBrowse link
G Esm1 endothelial cell-specific molecule 1 decreases expression EXP Vincristine results in decreased expression of ESM1 mRNA CTD PMID:20624997 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
decreases expression		 ISO bisphenol A inhibits the reaction [Vincristine results in decreased expression of ESR1 mRNA]; bisphenol A inhibits the reaction [Vincristine results in decreased expression of ESR1 protein]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR1 mRNA]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR1 protein]; Vincristine binds to and results in decreased activity of ESR1 protein
Vincristine results in decreased expression of ESR1 mRNA; Vincristine results in decreased expression of ESR1 protein		 CTD PMID:25752796 PMID:35263089 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
decreases expression		 ISO bisphenol A inhibits the reaction [Vincristine results in decreased expression of ESR2 mRNA]; bisphenol A inhibits the reaction [Vincristine results in decreased expression of ESR2 protein]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR2 mRNA]; Diethylhexyl Phthalate inhibits the reaction [Vincristine results in decreased expression of ESR2 protein]
Vincristine results in decreased expression of ESR2 mRNA; Vincristine results in decreased expression of ESR2 protein		 CTD PMID:35263089 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Evc EvC ciliary complex subunit 1 increases expression ISO Vincristine results in increased expression of EVC mRNA CTD PMID:23649840 NCBI chr14:73,456,181...73,498,955
Ensembl chr14:73,456,222...73,498,099 		JBrowse link
G Exo1 exonuclease 1 decreases expression ISO Vincristine results in decreased expression of EXO1 mRNA CTD PMID:23649840 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Exog exo/endonuclease G decreases expression ISO Vincristine results in decreased expression of EXOG mRNA CTD PMID:23649840 NCBI chr 8:119,184,974...119,204,819
Ensembl chr 8:119,185,136...119,204,672 		JBrowse link
G Ext1 exostosin glycosyltransferase 1 increases expression ISO Vincristine results in increased expression of EXT1 mRNA CTD PMID:23649840 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357 		JBrowse link
G F2 coagulation factor II, thrombin affects expression ISO Vincristine affects the expression of F2 protein CTD PMID:12542493 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO
EXP		 Vincristine results in increased expression of F3 mRNA; Vincristine results in increased expression of F3 protein CTD PMID:12542493 PMID:20624997 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fam13b family with sequence similarity 13, member B increases expression ISO Vincristine results in increased expression of FAM13B mRNA CTD PMID:23649840 NCBI chr18:26,040,285...26,107,112
Ensembl chr18:26,040,285...26,106,587 		JBrowse link
G Fam13c family with sequence similarity 13, member C increases expression ISO Vincristine results in increased expression of FAM13C mRNA CTD PMID:23649840 NCBI chr20:18,065,625...18,187,792
Ensembl chr20:18,065,628...18,187,592 		JBrowse link
G Fam171b family with sequence similarity 171, member B decreases expression ISO Vincristine results in decreased expression of FAM171B mRNA CTD PMID:23649840 NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127 		JBrowse link
G Fam174a family with sequence similarity 174, member A increases expression ISO Vincristine results in increased expression of FAM174A mRNA CTD PMID:23649840 NCBI chr 9:95,742,815...95,761,083
Ensembl chr 9:95,742,927...95,761,081 		JBrowse link
G Fam76b family with sequence similarity 76, member B decreases expression ISO Vincristine results in decreased expression of FAM76B mRNA CTD PMID:23649840 NCBI chr 8:10,689,396...10,711,847
Ensembl chr 8:10,688,963...10,711,861 		JBrowse link
G Fam81a family with sequence similarity 81, member A decreases expression ISO Vincristine results in decreased expression of FAM81A mRNA CTD PMID:23649840 NCBI chr 8:70,762,852...70,821,898
Ensembl chr 8:70,763,614...70,821,875 		JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression ISO Vincristine results in decreased expression of FAM83D mRNA CTD PMID:23649840 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192 		JBrowse link
G Fancf FA complementation group F decreases expression ISO Vincristine results in decreased expression of FANCF mRNA CTD PMID:23649840 NCBI chr 1:101,449,120...101,451,936
Ensembl chr 1:101,450,389...101,451,923 		JBrowse link
G Fancg FA complementation group G decreases expression ISO Vincristine results in decreased expression of FANCG mRNA CTD PMID:23649840 NCBI chr 5:57,230,287...57,240,067
Ensembl chr 5:57,231,685...57,240,029 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Vincristine results in increased expression of FAS mRNA CTD PMID:23649840 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression ISO Vincristine results in increased expression of FASLG protein CTD PMID:11716366 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fastkd2 FAST kinase domains 2 decreases expression ISO Vincristine results in decreased expression of FASTKD2 mRNA CTD PMID:23649840 NCBI chr 9:65,166,148...65,188,184
Ensembl chr 9:65,168,228...65,188,174 		JBrowse link
G Fbxl20 F-box and leucine-rich repeat protein 20 decreases expression ISO Vincristine results in decreased expression of FBXL20 mRNA CTD PMID:23649840 NCBI chr10:83,080,568...83,143,680
Ensembl chr10:83,086,551...83,144,162 		JBrowse link
G Fbxl4 F-box and leucine-rich repeat protein 4 decreases expression ISO Vincristine results in decreased expression of FBXL4 mRNA CTD PMID:23649840 NCBI chr 5:35,955,801...36,029,446
Ensembl chr 5:35,955,812...36,029,443 		JBrowse link
G Fbxo33 F-box protein 33 decreases expression ISO Vincristine results in decreased expression of FBXO33 mRNA CTD PMID:23649840 NCBI chr 6:76,900,619...76,934,232
Ensembl chr 6:76,900,631...76,932,669 		JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO Vincristine results in decreased expression of FBXO5 mRNA CTD PMID:23649840 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437 		JBrowse link
G Fbxo9 f-box protein 9 decreases expression ISO Vincristine results in decreased expression of FBXO9 mRNA CTD PMID:23649840 NCBI chr 8:78,958,482...78,984,015
Ensembl chr 8:78,958,483...78,983,949 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP Vincristine results in increased expression of FCGR2B mRNA CTD PMID:20624997 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression ISO Vincristine results in increased expression of FDFT1 mRNA CTD PMID:23649840 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 increases expression ISO Vincristine results in increased expression of FERMT2 mRNA CTD PMID:23649840 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Ffar2 free fatty acid receptor 2 decreases expression ISO Vincristine results in decreased expression of FFAR2 mRNA CTD PMID:23649840 NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases expression ISO Vincristine results in decreased expression of FGR mRNA CTD PMID:23649840 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Flot2 flotillin 2 decreases expression ISO Vincristine results in decreased expression of FLOT2 mRNA CTD PMID:23649840 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Vincristine results in decreased expression of FLT1 mRNA CTD PMID:23649840 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmnl3 formin-like 3 increases expression ISO Vincristine results in increased expression of FMNL3 mRNA CTD PMID:23649840 NCBI chr 7:130,454,270...130,505,626
Ensembl chr 7:130,454,275...130,505,626 		JBrowse link
G Fnbp1 formin binding protein 1 increases expression ISO Vincristine results in increased expression of FNBP1 mRNA CTD PMID:23649840 NCBI chr 3:14,309,067...14,424,378
Ensembl chr 3:14,309,640...14,424,881 		JBrowse link
G Fnbp4 formin binding protein 4 increases expression ISO Vincristine results in increased expression of FNBP4 mRNA CTD PMID:23649840 NCBI chr 3:76,733,012...76,763,077
Ensembl chr 3:76,733,027...76,763,079 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Vincristine results in increased expression of FOS protein CTD PMID:18930597 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression ISO Vincristine results in increased expression of FOSL2 mRNA CTD PMID:23649840 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxk2 forkhead box K2 decreases expression ISO Vincristine results in decreased expression of FOXK2 mRNA CTD PMID:23649840 NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563 		JBrowse link
G Foxo1 forkhead box O1 multiple interactions
decreases expression		 EXP Quercetin inhibits the reaction [Vincristine results in decreased expression of FOXO1 mRNA] CTD PMID:33038355 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Foxp1 forkhead box P1 increases expression ISO Vincristine results in increased expression of FOXP1 mRNA CTD PMID:23649840 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G Fry FRY microtubule binding protein decreases expression ISO Vincristine results in decreased expression of FRY mRNA CTD PMID:23649840 NCBI chr12:4,493,890...4,887,118
Ensembl chr12:4,493,891...4,799,116 		JBrowse link
G Fscn1 fascin actin-bundling protein 1 increases expression ISO Vincristine results in increased expression of FSCN1 mRNA CTD PMID:23649840 NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211 		JBrowse link
G Fsd1l fibronectin type III and SPRY domain containing 1-like increases expression ISO Vincristine results in increased expression of FSD1L mRNA CTD PMID:23649840 NCBI chr 5:68,258,877...68,334,931
Ensembl chr 5:68,258,932...68,334,928 		JBrowse link
G Fubp1 far upstream element binding protein 1 decreases expression ISO Vincristine results in decreased expression of FUBP1 mRNA CTD PMID:23649840 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Fut11 fucosyltransferase 11 decreases expression ISO Vincristine results in decreased expression of FUT11 mRNA CTD PMID:23649840 NCBI chr15:3,598,768...3,602,328
Ensembl chr15:3,598,758...3,602,356 		JBrowse link
G G3bp1 G3BP stress granule assembly factor 1 increases expression ISO Vincristine results in increased expression of G3BP1 mRNA CTD PMID:23649840 NCBI chr10:39,586,864...39,620,268
Ensembl chr10:39,586,864...39,620,268 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP
ISO		 Vincristine results in increased expression of GADD45A mRNA CTD PMID:20624997 PMID:23649840 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression EXP Vincristine results in increased expression of GADD45B mRNA CTD PMID:20624997 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression EXP Vincristine results in increased expression of GADD45G mRNA CTD PMID:20624997 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Garin1b golgi associated RAB2 interactor 1B increases expression ISO Vincristine results in increased expression of GARIN1B mRNA CTD PMID:23649840 NCBI chr 4:57,915,184...57,938,593
Ensembl chr 4:57,920,790...57,938,591 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase decreases expression ISO Vincristine results in decreased expression of GART mRNA CTD PMID:23649840 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Gas7 growth arrest specific 7 decreases expression EXP Vincristine results in decreased expression of GAS7 mRNA CTD PMID:20624997 NCBI chr10:52,152,718...52,383,283
Ensembl chr10:52,152,493...52,383,276 		JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO Vincristine results in increased expression of GBP1 mRNA CTD PMID:23649840 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131 		JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO Vincristine results in increased expression of GBP2 mRNA CTD PMID:23649840 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gbp6 guanylate binding protein family member 6 decreases expression ISO Vincristine results in decreased expression of GBP6 mRNA CTD PMID:23649840 NCBI chr14:4,730,286...4,756,508
Ensembl chr14:4,730,453...4,839,062
Ensembl chr14:4,730,453...4,839,062 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine CTD PMID:10900222 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
decreases expression		 ISO [GCLC protein co-treated with GCLM protein] results in decreased susceptibility to Vincristine
Vincristine results in decreased expression of GCLM mRNA		 CTD PMID:10900222 PMID:23649840 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Vincristine results in increased expression of GDF15 mRNA CTD PMID:23649840 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression
multiple interactions		 EXP
ISO		 Vincristine results in increased expression of GFAP protein
Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GFAP protein]; KN 93 inhibits the reaction [Vincristine results in increased expression of GFAP protein]
Quercetin inhibits the reaction [Vincristine results in increased expression of GFAP protein]		 CTD PMID:33038355 PMID:34286406 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor decreases expression ISO Vincristine results in decreased expression of GFI1 mRNA CTD PMID:23649840 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814 		JBrowse link
G Gfm1 G elongation factor, mitochondrial 1 increases expression ISO Vincristine results in increased expression of GFM1 mRNA CTD PMID:23649840 NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
multiple interactions		 ISO Vincristine results in increased expression of GJA1 mRNA; Vincristine results in increased expression of GJA1 protein
Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; Ascorbic Acid inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; gap 27 peptide inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; gap 27 peptide inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; GJA1 protein promotes the reaction [Vincristine results in increased secretion of IL1B protein]; GJA1 protein promotes the reaction [Vincristine results in increased secretion of IL6 protein]; KN 62 inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; KN 93 inhibits the reaction [Vincristine results in increased expression of GJA1 mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of GJA1 protein]; zinc chloride inhibits the reaction [Vincristine results in increased expression of GJA1 protein]		 CTD PMID:34286406 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gjc1 gap junction protein, gamma 1 decreases expression ISO Vincristine results in decreased expression of GJC1 mRNA CTD PMID:23649840 NCBI chr10:87,758,192...87,785,443
Ensembl chr10:87,760,528...87,785,867 		JBrowse link
G Gli1 GLI family zinc finger 1 increases response to substance ISO GLI1 gene SNP results in increased susceptibility to Vincristine CTD PMID:20864405 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Glipr1 GLI pathogenesis-related 1 increases expression ISO Vincristine results in increased expression of GLIPR1 mRNA CTD PMID:23649840 NCBI chr 7:47,487,342...47,498,974
Ensembl chr 7:47,487,345...47,498,429 		JBrowse link
G Gmfb glia maturation factor, beta increases expression ISO Vincristine results in increased expression of GMFB mRNA CTD PMID:23649840 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331 		JBrowse link
G Gmppb GDP-mannose pyrophosphorylase B decreases expression ISO Vincristine results in decreased expression of GMPPB mRNA CTD PMID:23649840 NCBI chr 8:108,737,429...108,740,437
Ensembl chr 8:108,693,060...108,767,286 		JBrowse link
G Gna15 G protein subunit alpha 15 increases expression ISO Vincristine results in increased expression of GNA15 mRNA CTD PMID:23649840 NCBI chr 7:8,184,632...8,205,508
Ensembl chr 7:8,184,861...8,205,508 		JBrowse link
G Gng2 G protein subunit gamma 2 increases expression ISO Vincristine results in increased expression of GNG2 mRNA CTD PMID:23649840 NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183 		JBrowse link
G Gon4l gon-4 like increases expression ISO Vincristine results in increased expression of GON4L mRNA CTD PMID:23649840 NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634 		JBrowse link
G Gopc golgi associated PDZ and coiled-coil motif containing decreases expression ISO Vincristine results in decreased expression of GOPC mRNA CTD PMID:23649840 NCBI chr20:31,727,617...31,776,904
Ensembl chr20:31,727,620...31,776,903 		JBrowse link
G Gpatch11 G patch domain containing 11 decreases expression ISO Vincristine results in decreased expression of GPATCH11 mRNA CTD PMID:23649840 NCBI chr 6:16,229,933...16,243,305
Ensembl chr 6:16,233,059...16,243,238 		JBrowse link
G Gpatch2 G patch domain containing 2 increases expression ISO Vincristine results in increased expression of GPATCH2 mRNA CTD PMID:23649840 NCBI chr13:98,784,993...98,925,696
Ensembl chr13:98,784,969...98,925,661 		JBrowse link
G Gpatch2l G patch domain containing 2-like increases expression ISO Vincristine results in increased expression of GPATCH2L mRNA CTD PMID:23649840 NCBI chr 6:105,883,383...105,935,644
Ensembl chr 6:105,883,460...105,934,888 		JBrowse link
G Gpbp1l1 GC-rich promoter binding protein 1-like 1 increases expression ISO Vincristine results in increased expression of GPBP1L1 mRNA CTD PMID:23649840 NCBI chr 5:130,009,768...130,050,636
Ensembl chr 5:130,023,137...130,050,459 		JBrowse link
G Gpc3 glypican 3 increases response to substance ISO GPC3 mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 decreases expression ISO Vincristine results in decreased expression of GPD2 mRNA CTD PMID:23649840 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901 		JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Vincristine results in increased expression of GPNMB mRNA CTD PMID:23649840 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpr132 G protein-coupled receptor 132 increases expression ISO Vincristine results in increased expression of GPR132 mRNA CTD PMID:23649840 NCBI chr 6:131,924,061...131,943,327
Ensembl chr 6:131,924,160...131,942,168 		JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression ISO Vincristine results in increased expression of GPR137B mRNA CTD PMID:23649840 NCBI chr17:86,003,635...86,041,841
Ensembl chr17:85,966,921...86,041,835 		JBrowse link
G Gpr180 G protein-coupled receptor 180 decreases expression ISO Vincristine results in decreased expression of GPR180 mRNA CTD PMID:23649840 NCBI chr15:95,195,782...95,224,955
Ensembl chr15:95,199,777...95,228,373 		JBrowse link
G Gpr55 G protein-coupled receptor 55 increases expression ISO Vincristine results in increased expression of GPR55 mRNA CTD PMID:23649840 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613 		JBrowse link
G Gpr63 G protein-coupled receptor 63 decreases expression ISO Vincristine results in decreased expression of GPR63 mRNA CTD PMID:23649840 NCBI chr 5:38,672,548...38,727,224
Ensembl chr 5:38,635,472...38,727,677 		JBrowse link
G Gpr84 G protein-coupled receptor 84 increases expression ISO Vincristine results in increased expression of GPR84 mRNA CTD PMID:23649840 NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity		 EXP Quercetin inhibits the reaction [Vincristine results in increased activity of GPT protein] CTD PMID:36808657 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gramd2b GRAM domain containing 2B increases expression ISO Vincristine results in increased expression of GRAMD2B mRNA CTD PMID:23649840 NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953 		JBrowse link
G Grap2 GRB2-related adaptor protein 2 decreases expression ISO Vincristine results in decreased expression of GRAP2 mRNA CTD PMID:23649840 NCBI chr 7:112,117,142...112,190,880
Ensembl chr 7:112,117,142...112,190,877 		JBrowse link
G Gspt1 G1 to S phase transition 1 increases expression ISO Vincristine results in increased expression of GSPT1 mRNA CTD PMID:23649840 NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance
decreases response to substance
multiple interactions		 ISO GSTM1 gene polymorphism affects the susceptibility to Vincristine
GSTM1 protein results in decreased susceptibility to Vincristine
Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine]		 CTD PMID:15044619 PMID:15713801 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases response to substance
multiple interactions		 ISO GSTP1 protein results in decreased susceptibility to Vincristine
GSTP1 protein promotes the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]		 CTD PMID:10900222 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gtf3c3 general transcription factor IIIC subunit 3 increases expression ISO Vincristine results in increased expression of GTF3C3 mRNA CTD PMID:23649840 NCBI chr 9:55,882,252...55,943,037
Ensembl chr 9:55,883,721...55,942,967 		JBrowse link
G Gtpbp3 GTP binding protein 3 decreases expression ISO Vincristine results in decreased expression of GTPBP3 mRNA CTD PMID:23649840 NCBI chr16:18,175,766...18,180,857
Ensembl chr16:18,175,766...18,180,857 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO [CEP 33779 results in increased susceptibility to Vincristine] which results in increased phosphorylation of H2AX protein; [NVP-BSK805 results in increased susceptibility to Vincristine] which results in increased phosphorylation of H2AX protein CTD PMID:28669723 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G H2bc12 H2B clustered histone 12 increases expression ISO Vincristine results in increased expression of H2BC12 mRNA CTD PMID:23649840 NCBI chr17:42,485,699...42,486,162 JBrowse link
G H2bc3 H2B clustered histone 3 increases expression ISO Vincristine results in increased expression of H2BC3 mRNA CTD PMID:23649840 NCBI chr17:41,380,056...41,380,686 JBrowse link
G H2bc6 H2B clustered histone 6 increases expression ISO Vincristine results in increased expression of H2BC6 mRNA CTD PMID:23649840 NCBI chr17:41,520,775...41,521,238 JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression ISO Vincristine results in decreased expression of HAMP mRNA CTD PMID:25633564 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Haus2 HAUS augmin like complex subunit 2 decreases expression ISO Vincristine results in decreased expression of HAUS2 mRNA CTD PMID:23649840 NCBI chr 3:107,553,146...107,565,982
Ensembl chr 3:107,553,161...107,565,157 		JBrowse link
G Hbb hemoglobin subunit beta decreases expression ISO Vincristine results in decreased expression of HBB mRNA CTD PMID:23649840 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbb-b1 hemoglobin, beta adult major chain decreases expression ISO Vincristine results in decreased expression of HBD mRNA CTD PMID:23649840 NCBI chr 1:158,224,175...158,231,675
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hdac1 histone deacetylase 1 decreases expression EXP Vincristine results in decreased expression of HDAC1 protein CTD PMID:27474498 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac4 histone deacetylase 4 decreases expression EXP Vincristine results in decreased expression of HDAC4 protein CTD PMID:27474498 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hdac9 histone deacetylase 9 decreases expression ISO Vincristine results in decreased expression of HDAC9 mRNA CTD PMID:23649840 NCBI chr 6:50,762,074...51,624,311
Ensembl chr 6:50,763,590...51,625,333 		JBrowse link
G Hdhd3 haloacid dehalogenase-like hydrolase domain containing 3 decreases expression ISO Vincristine results in decreased expression of HDHD3 mRNA CTD PMID:23649840 NCBI chr 5:75,951,308...75,954,775
Ensembl chr 5:75,946,013...75,955,266 		JBrowse link
G Hectd4 HECT domain E3 ubiquitin protein ligase 4 increases expression ISO Vincristine results in increased expression of HECTD4 mRNA CTD PMID:23649840 NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987 		JBrowse link
G Hells helicase, lymphoid specific decreases expression ISO Vincristine results in decreased expression of HELLS mRNA CTD PMID:23649840 NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844 		JBrowse link
G Heph hephaestin increases expression ISO Vincristine results in increased expression of HEPH mRNA CTD PMID:23649840 NCBI chr  X:61,151,131...61,402,980
Ensembl chr  X:61,296,345...61,402,980 		JBrowse link
G Hhat hedgehog acyltransferase increases expression ISO Vincristine results in increased expression of HHAT mRNA CTD PMID:23649840 NCBI chr13:104,024,507...104,283,580
Ensembl chr13:104,010,916...104,282,893 		JBrowse link
G Hic1 HIC ZBTB transcriptional repressor 1 decreases expression ISO Vincristine results in decreased expression of HIC1 mRNA CTD PMID:23649840 NCBI chr10:60,014,520...60,019,475
Ensembl chr10:60,011,528...60,019,475 		JBrowse link
G Hilpda hypoxia inducible lipid droplet-associated decreases expression ISO Vincristine results in decreased expression of HILPDA mRNA CTD PMID:23649840 NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557 		JBrowse link
G Hint1 histidine triad nucleotide binding protein 1 decreases expression ISO Vincristine results in decreased expression of HINT1 mRNA CTD PMID:23649840 NCBI chr10:38,989,516...38,993,259
Ensembl chr 4:92,100,973...92,101,568 		JBrowse link
G Hint3 histidine triad nucleotide binding protein 3 increases expression ISO Vincristine results in increased expression of HINT3 mRNA CTD PMID:23649840 NCBI chr 1:27,035,936...27,045,799
Ensembl chr 1:27,035,905...27,047,721 		JBrowse link
G Hist1h2al1 histone cluster 1 H2A family like 1 increases expression ISO Vincristine results in increased expression of H2AC6 mRNA CTD PMID:23649840 NCBI chr17:42,707,954...42,708,420 JBrowse link
G Hist1h2bc histone cluster 1, H2bc increases expression ISO Vincristine results in increased expression of H2BC21 mRNA CTD PMID:23649840 NCBI chr17:42,692,335...42,696,601
Ensembl chr17:42,694,723...42,696,642 		JBrowse link
G Hist1h2bd histone cluster 1 H2B family member D increases expression ISO Vincristine results in increased expression of H2BC5 mRNA CTD PMID:23649840 NCBI chr17:42,792,887...42,793,268 JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q increases expression ISO Vincristine results in increased expression of H2BC7 mRNA CTD PMID:23649840 NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153 		JBrowse link
G Hivep3 HIVEP zinc finger 3 increases expression ISO Vincristine results in increased expression of HIVEP3 mRNA CTD PMID:23649840 NCBI chr 5:133,325,327...133,727,797
Ensembl chr 5:133,658,052...133,727,795 		JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member increases expression ISO Vincristine results in increased expression of HLF mRNA CTD PMID:23649840 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935 		JBrowse link
G Hmcn1 hemicentin 1 increases response to substance ISO HMCN1 mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr13:62,615,461...63,084,524
Ensembl chr13:62,615,461...63,084,524 		JBrowse link
G Hmga2 high mobility group AT-hook 2 decreases expression ISO Vincristine results in decreased expression of HMGA2 mRNA CTD PMID:23649840 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgb1 high mobility group box 1 decreases expression
increases secretion
decreases response to substance		 EXP
ISO		 Vincristine results in decreased expression of HMGB1 protein
Vincristine results in increased secretion of HMGB1 protein
HMGB1 protein results in decreased susceptibility to Vincristine		 CTD PMID:27474498 PMID:27807322 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 decreases expression ISO Vincristine results in decreased expression of HMGN5 mRNA CTD PMID:23649840 NCBI chr  X:74,085,871...74,094,488
Ensembl chr  X:74,085,875...74,094,441 		JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
decreases activity
multiple interactions
increases expression		 ISO
EXP		 Vincristine results in decreased expression of HMOX1 mRNA
Vincristine results in decreased expression of HMOX1 protein
Vincristine results in decreased activity of HMOX1 protein
Quercetin inhibits the reaction [Vincristine results in decreased activity of HMOX1 protein]; Quercetin inhibits the reaction [Vincristine results in decreased expression of HMOX1 protein]
Vincristine results in increased expression of HMOX1 mRNA		 CTD PMID:20624997 PMID:23649840 PMID:33038355 PMID:36808657 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 decreases expression ISO Vincristine results in decreased expression of HNRNPA2B1 mRNA CTD PMID:23649840 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO Vincristine results in decreased expression of HNRNPD mRNA CTD PMID:23649840 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like decreases expression ISO Vincristine results in decreased expression of HNRNPDL mRNA CTD PMID:23649840 NCBI chr14:9,557,430...9,563,659
Ensembl chr14:9,557,425...9,562,506 		JBrowse link
G Hnrnpr heterogeneous nuclear ribonucleoprotein R decreases expression ISO Vincristine results in decreased expression of HNRNPR mRNA CTD PMID:23649840 NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U decreases expression ISO Vincristine results in decreased expression of HNRNPU mRNA CTD PMID:23649840 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Hook1 hook microtubule-tethering protein 1 decreases expression ISO Vincristine results in decreased expression of HOOK1 mRNA CTD PMID:23649840 NCBI chr 5:110,824,501...110,887,791
Ensembl chr 5:110,824,501...110,887,787 		JBrowse link
G Hook3 hook microtubule-tethering protein 3 decreases expression ISO Vincristine results in decreased expression of HOOK3 mRNA CTD PMID:23649840 NCBI chr16:65,954,293...66,058,812
Ensembl chr16:65,954,350...66,061,338 		JBrowse link
G Hoxb7 homeo box B7 decreases expression ISO Vincristine results in decreased expression of HOXB7 mRNA CTD PMID:23649840 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034 		JBrowse link
G Hpdl 4-hydroxyphenylpyruvate dioxygenase-like decreases expression ISO Vincristine results in decreased expression of HPDL mRNA CTD PMID:23649840 NCBI chr 5:130,286,627...130,288,233
Ensembl chr 5:130,286,631...130,288,233 		JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression ISO Vincristine results in increased expression of HRAS mRNA CTD PMID:16001973 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO Vincristine results in decreased expression of HS2ST1 mRNA CTD PMID:23649840 NCBI chr 2:233,508,018...233,641,769
Ensembl chr 2:233,508,021...233,641,769 		JBrowse link
G Hspa14 heat shock protein family A (Hsp70) member 14 decreases expression ISO Vincristine results in decreased expression of HSPA14 mRNA CTD PMID:23649840 NCBI chr17:74,728,945...74,749,727
Ensembl chr17:74,728,899...74,749,727 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 EXP Vincristine results in increased expression of HSPA5 mRNA
Quercetin inhibits the reaction [Vincristine results in increased expression of HSPA5 mRNA]		 CTD PMID:33038355 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspb2 heat shock protein family B (small) member 2 decreases response to substance ISO HSPB2 protein results in decreased susceptibility to Vincristine CTD PMID:17524270 NCBI chr 8:51,093,267...51,094,528
Ensembl chr 8:51,081,342...51,094,533 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 decreases expression ISO Vincristine results in decreased expression of HSPD1 mRNA CTD PMID:23649840 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
increases expression		 EXP [alpha-phenyl-1-(2-phenylethyl)-4-piperidinemethanol binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Vincristine
Vincristine results in increased expression of HTR2A protein		 CTD PMID:18930597 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Hyls1 HYLS1, centriolar and ciliogenesis associated decreases expression ISO Vincristine results in decreased expression of HYLS1 mRNA CTD PMID:23649840 NCBI chr 8:33,912,692...33,921,760
Ensembl chr 8:33,912,692...33,921,760 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO
EXP		 Vincristine results in increased expression of ICAM1 mRNA CTD PMID:20624997 PMID:23649840 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Icam4 intercellular adhesion molecule 4, Landsteiner-Wiener blood group increases expression ISO Vincristine results in increased expression of ICAM4 mRNA CTD PMID:23649840 NCBI chr 8:19,566,075...19,567,171
Ensembl chr 8:19,566,075...19,567,171 		JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Vincristine results in increased expression of ID2 mRNA CTD PMID:23649840 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Id3 inhibitor of DNA binding 3 increases response to substance ISO ID3 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Ier3 immediate early response 3 increases expression ISO Vincristine results in increased expression of IER3 mRNA CTD PMID:23649840 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583 		JBrowse link
G Ifi44 interferon-induced protein 44 increases expression ISO Vincristine results in increased expression of IFI44 mRNA CTD PMID:23649840 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844 		JBrowse link
G Ifi44l interferon-induced protein 44-like increases expression ISO Vincristine results in increased expression of IFI44L mRNA CTD PMID:23649840 NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 increases expression ISO Vincristine results in increased expression of IFIH1 mRNA CTD PMID:23649840 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 increases expression ISO Vincristine results in increased expression of IFIT2 mRNA CTD PMID:23649840 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635 		JBrowse link
G Ifng interferon gamma increases expression ISO Vincristine results in increased expression of IFNG mRNA CTD PMID:23649840 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Vincristine results in decreased expression of IFRD1 mRNA CTD PMID:23649840 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990 		JBrowse link
G Ift20 intraflagellar transport 20 increases expression ISO Vincristine results in increased expression of IFT20 mRNA CTD PMID:23649840 NCBI chr10:63,432,597...63,438,125
Ensembl chr10:63,432,633...63,438,124 		JBrowse link
G Ift25 intraflagellar transport 25 decreases expression ISO Vincristine results in decreased expression of IFT25 mRNA CTD PMID:23649840 NCBI chr 5:122,035,588...122,062,421
Ensembl chr 5:122,035,581...122,062,421 		JBrowse link
G Ift43 intraflagellar transport 43 increases expression ISO Vincristine results in increased expression of IFT43 mRNA CTD PMID:23649840 NCBI chr 6:105,729,734...105,806,257
Ensembl chr 6:105,729,792...105,806,257 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases response to substance		 ISO Vincristine promotes the reaction [NVP ADW742 inhibits the reaction [IGF1 protein results in increased phosphorylation of AKT1 protein]]
IGF1 protein results in decreased susceptibility to Vincristine		 CTD PMID:9452187 PMID:16740780 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 decreases expression ISO Vincristine results in decreased expression of IGHG1 mRNA CTD PMID:23649840 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
G Igkc immunoglobulin kappa constant decreases expression ISO Vincristine results in decreased expression of IGKC mRNA CTD PMID:23649840
G Igkv8-30l1 immunoglobulin kappa chain variable 8-30 like 1 decreases expression ISO Vincristine results in decreased expression of IGKV4-1 mRNA CTD PMID:23649840 NCBI chr 4:101,838,285...101,839,132 JBrowse link
G Ikzf2 IKAROS family zinc finger 2 decreases expression ISO Vincristine results in decreased expression of IKZF2 mRNA CTD PMID:23649840 NCBI chr 9:71,046,038...71,191,296
Ensembl chr 9:71,042,440...71,190,867 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO Vincristine results in increased expression of IL10RA mRNA CTD PMID:23649840 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Il15 interleukin 15 increases expression ISO Vincristine results in increased expression of IL15 mRNA CTD PMID:23649840 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Il17rb interleukin 17 receptor B decreases expression ISO Vincristine results in decreased expression of IL17RB mRNA CTD PMID:23649840 NCBI chr16:5,180,431...5,194,125
Ensembl chr16:5,180,432...5,194,125 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
increases secretion		 EXP
ISO		 Vincristine results in increased expression of IL1B mRNA; Vincristine results in increased expression of IL1B protein
gap 27 peptide inhibits the reaction [Vincristine results in increased secretion of IL1B protein]; GJA1 protein promotes the reaction [Vincristine results in increased secretion of IL1B protein]; KN 93 inhibits the reaction [Vincristine results in increased expression of IL1B mRNA]
coenzyme Q10 inhibits the reaction [Vincristine results in increased expression of IL1B protein]; Sumatriptan inhibits the reaction [Vincristine results in increased expression of IL1B mRNA]		 CTD PMID:20624997 PMID:29958920 PMID:34286406 PMID:34939713 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression ISO Vincristine results in increased expression of IL1R1 mRNA CTD PMID:23649840 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937 		JBrowse link
G Il2 interleukin 2 multiple interactions
increases expression		 EXP tropisetron inhibits the reaction [Vincristine results in increased expression of IL2 protein] CTD PMID:24374478 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il23a interleukin 23 subunit alpha increases expression ISO Vincristine results in increased expression of IL23A mRNA CTD PMID:23649840 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il36g interleukin 36, gamma increases expression ISO Vincristine results in increased expression of IL36G mRNA CTD PMID:23649840 NCBI chr 3:6,948,323...6,954,485
Ensembl chr 3:6,948,297...6,954,480 		JBrowse link
G Il6 interleukin 6 affects response to substance
multiple interactions
increases secretion
increases expression		 EXP
ISO		 IL6 protein affects the susceptibility to Vincristine
gap 27 peptide inhibits the reaction [Vincristine results in increased secretion of IL6 protein]; GJA1 protein promotes the reaction [Vincristine results in increased secretion of IL6 protein]; KN 93 inhibits the reaction [Vincristine results in increased expression of IL6 mRNA]
Vincristine results in increased expression of IL6 mRNA; Vincristine results in increased expression of IL6 protein		 CTD PMID:16001973 PMID:18270703 PMID:18652822 PMID:23649840 PMID:34286406 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il7 interleukin 7 increases expression ISO Vincristine results in increased expression of IL7 mRNA CTD PMID:23649840 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Ildr1 immunoglobulin-like domain containing receptor 1 increases expression ISO Vincristine results in increased expression of ILDR1 mRNA CTD PMID:23649840 NCBI chr11:64,085,774...64,118,760
Ensembl chr11:64,008,566...64,118,760 		JBrowse link
G Ildr2 immunoglobulin-like domain containing receptor 2 decreases expression ISO Vincristine results in decreased expression of ILDR2 mRNA CTD PMID:23649840 NCBI chr13:78,518,770...78,580,627
Ensembl chr13:78,518,802...78,576,924 		JBrowse link
G Impa2 inositol monophosphatase 2 decreases expression ISO Vincristine results in decreased expression of IMPA2 mRNA CTD PMID:23649840 NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641 		JBrowse link
G Ina internexin neuronal intermediate filament protein, alpha multiple interactions ISO INA affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine] CTD PMID:21246521 NCBI chr 1:245,896,775...245,908,330
Ensembl chr 1:245,896,775...245,908,330 		JBrowse link
G Ing2 inhibitor of growth family, member 2 decreases expression ISO Vincristine results in decreased expression of ING2 mRNA CTD PMID:23649840 NCBI chr16:44,573,592...44,584,180
Ensembl chr16:44,575,597...44,583,482 		JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Vincristine results in decreased expression of INHA mRNA CTD PMID:20624997 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Vincristine results in increased expression of INHBE mRNA CTD PMID:23649840 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Inpp1 inositol polyphosphate-1-phosphatase increases expression ISO Vincristine results in increased expression of INPP1 mRNA CTD PMID:23649840 NCBI chr 9:48,688,037...48,717,793
Ensembl chr 9:48,669,901...48,717,793 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B increases expression ISO Vincristine results in increased expression of INPP4B mRNA CTD PMID:23649840 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Ints11 integrator complex subunit 11 decreases expression ISO Vincristine results in decreased expression of INTS11 mRNA CTD PMID:23649840 NCBI chr 5:166,479,134...166,497,956
Ensembl chr 5:166,479,155...166,497,651 		JBrowse link
G Ints5 integrator complex subunit 5 decreases expression ISO Vincristine results in decreased expression of INTS5 mRNA CTD PMID:23649840 NCBI chr 1:205,788,906...205,793,685
Ensembl chr 1:205,788,906...205,793,685 		JBrowse link
G Ipo5 importin 5 decreases expression ISO Vincristine results in decreased expression of IPO5 mRNA CTD PMID:23649840 NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126 		JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 decreases expression ISO Vincristine results in decreased expression of IQGAP2 mRNA CTD PMID:23649840 NCBI chr 2:26,894,836...27,170,270
Ensembl chr 2:26,894,825...27,170,279 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO Vincristine results in increased expression of IRAK2 mRNA CTD PMID:23649840 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Ireb2 iron responsive element binding protein 2 increases expression ISO Vincristine results in increased expression of IREB2 mRNA CTD PMID:23649840 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO Vincristine results in increased expression of IRF1 mRNA CTD PMID:23649840 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 increases expression ISO Vincristine results in increased expression of ISG20 mRNA CTD PMID:23649840 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027 		JBrowse link
G Islr immunoglobulin superfamily containing leucine-rich repeat increases expression ISO Vincristine results in increased expression of ISLR mRNA CTD PMID:23649840 NCBI chr 8:58,571,155...58,574,128
Ensembl chr 8:58,570,777...58,574,130 		JBrowse link
G Itga1 integrin subunit alpha 1 increases response to substance ISO ITGA1 mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 2:46,646,125...46,812,237
Ensembl chr 2:46,653,193...46,812,238 		JBrowse link
G Itga4 integrin subunit alpha 4 decreases expression ISO Vincristine results in decreased expression of ITGA4 mRNA CTD PMID:23649840 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO Vincristine results in increased expression of ITGAM mRNA CTD PMID:23649840 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb1bp2 integrin subunit beta 1 binding protein 2 decreases expression ISO Vincristine results in decreased expression of ITGB1BP2 mRNA CTD PMID:23649840 NCBI chr  X:66,572,537...66,577,174
Ensembl chr  X:66,572,537...66,577,174 		JBrowse link
G Itgb7 integrin subunit beta 7 decreases expression ISO Vincristine results in decreased expression of ITGB7 mRNA CTD PMID:23649840 NCBI chr 7:133,347,927...133,364,955
Ensembl chr 7:133,347,960...133,364,876 		JBrowse link
G Itgb8 integrin subunit beta 8 increases expression ISO Vincristine results in increased expression of ITGB8 mRNA CTD PMID:23649840 NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B decreases expression ISO Vincristine results in decreased expression of ITPKB mRNA CTD PMID:23649840 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression ISO Vincristine results in increased expression of ITPR1 mRNA CTD PMID:23649840 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Itprid2 ITPR interacting domain containing 2 decreases expression ISO Vincristine results in decreased expression of ITPRID2 mRNA CTD PMID:23649840 NCBI chr 3:64,536,707...64,573,978
Ensembl chr 3:64,536,707...64,573,978 		JBrowse link
G Itpripl1 ITPRIP like 1 decreases expression ISO Vincristine results in decreased expression of ITPRIPL1 mRNA CTD PMID:23649840 NCBI chr 3:114,403,123...114,407,917
Ensembl chr 3:114,402,270...114,414,497 		JBrowse link
G Ivl involucrin increases expression ISO Vincristine results in increased expression of IVL mRNA CTD PMID:23649840 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100 		JBrowse link
G Ivns1abp influenza virus NS1A binding protein decreases expression ISO Vincristine results in decreased expression of IVNS1ABP mRNA CTD PMID:23649840 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701 		JBrowse link
G Jade2 jade family PHD finger 2 increases expression ISO Vincristine results in increased expression of JADE2 mRNA CTD PMID:23649840 NCBI chr10:36,075,239...36,124,210
Ensembl chr10:36,078,917...36,116,984 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM decreases expression ISO Vincristine results in decreased expression of JCHAIN mRNA CTD PMID:23649840 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Jmjd1c jumonji domain containing 1C increases expression ISO Vincristine results in increased expression of JMJD1C mRNA CTD PMID:23649840 NCBI chr20:21,332,147...21,494,220
Ensembl chr20:21,332,147...21,463,122 		JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 decreases expression ISO Vincristine results in decreased expression of JPT1 mRNA CTD PMID:23649840 NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO Vincristine results in increased expression of JUN mRNA CTD PMID:23649840 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kat2b lysine acetyltransferase 2B increases expression ISO Vincristine results in increased expression of KAT2B mRNA CTD PMID:16001973 NCBI chr 9:6,562,525...6,667,064
Ensembl chr 9:6,562,288...6,667,064 		JBrowse link
G Kcmf1 potassium channel modulatory factor 1 decreases expression ISO Vincristine results in decreased expression of KCMF1 mRNA CTD PMID:23649840 NCBI chr 4:104,888,452...104,950,234
Ensembl chr 4:104,889,847...104,950,234 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 increases response to substance ISO KCNA5 protein results in increased susceptibility to Vincristine CTD PMID:17428690 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcnmb1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 increases expression ISO Vincristine results in increased expression of KCNMB1 mRNA CTD PMID:23649840 NCBI chr10:18,557,510...18,614,824
Ensembl chr10:18,557,904...18,565,798 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 increases expression ISO Vincristine results in increased expression of KCNN2 mRNA CTD PMID:23649840 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Kdm2b lysine demethylase 2B increases expression ISO Vincristine results in increased expression of KDM2B mRNA CTD PMID:23649840 NCBI chr12:33,566,530...33,701,366
Ensembl chr12:33,574,657...33,701,355 		JBrowse link
G Kdsr 3-ketodihydrosphingosine reductase decreases expression ISO Vincristine results in decreased expression of KDSR mRNA CTD PMID:23649840 NCBI chr13:22,862,117...22,894,118
Ensembl chr13:22,862,117...22,894,108 		JBrowse link
G Klf12 KLF transcription factor 12 decreases expression ISO Vincristine results in decreased expression of KLF12 mRNA CTD PMID:23649840 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056 		JBrowse link
G Klf6 KLF transcription factor 6 increases expression ISO Vincristine results in increased expression of KLF6 mRNA CTD PMID:23649840 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Klhl14 kelch-like family member 14 decreases expression ISO Vincristine results in decreased expression of KLHL14 mRNA CTD PMID:23649840 NCBI chr18:12,804,253...12,917,828
Ensembl chr18:12,804,253...12,917,828 		JBrowse link
G Klhl28 kelch-like family member 28 increases expression ISO Vincristine results in increased expression of KLHL28 mRNA CTD PMID:23649840 NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164 		JBrowse link
G Kmt5b lysine methyltransferase 5B increases expression ISO Vincristine results in increased expression of KMT5B mRNA CTD PMID:23649840 NCBI chr 1:201,000,444...201,049,819
Ensembl chr 1:201,000,444...201,049,819 		JBrowse link
G Kpna2 karyopherin subunit alpha 2 decreases expression ISO Vincristine results in decreased expression of KPNA2 mRNA CTD PMID:23649840 NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150 		JBrowse link
G Krt23 keratin 23 increases response to substance ISO KRT23 mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983 		JBrowse link
G Krt7 keratin 7 increases expression ISO Vincristine results in increased expression of KRT7 mRNA CTD PMID:23649840 NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052 		JBrowse link
G Kynu kynureninase increases expression ISO Vincristine results in increased expression of KYNU mRNA CTD PMID:23649840 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Lactb2 lactamase, beta 2 decreases expression ISO Vincristine results in decreased expression of LACTB2 mRNA CTD PMID:23649840 NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429 		JBrowse link
G Lama2 laminin subunit alpha 2 increases response to substance ISO LAMA2 mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530 		JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 increases expression ISO Vincristine results in increased expression of LAMP3 mRNA CTD PMID:23649840 NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784 		JBrowse link
G Larp1b La ribonucleoprotein 1B decreases expression ISO Vincristine results in decreased expression of LARP1B mRNA CTD PMID:23649840 NCBI chr 2:123,936,057...123,969,254
Ensembl chr 2:123,935,983...123,968,896 		JBrowse link
G Lbh LBH regulator of WNT signaling pathway decreases expression ISO Vincristine results in decreased expression of LBH mRNA CTD PMID:23649840 NCBI chr 6:22,569,238...22,593,056
Ensembl chr 6:22,568,834...22,593,079 		JBrowse link
G Lce1b late cornified envelope 1B increases expression ISO Vincristine results in increased expression of LCE1B mRNA CTD PMID:23649840 NCBI chr 2:178,255,351...178,257,533
Ensembl chr 2:178,256,213...178,257,985 		JBrowse link
G Lcor ligand dependent nuclear receptor corepressor increases expression ISO Vincristine results in increased expression of LCOR mRNA CTD PMID:23649840 NCBI chr 1:240,298,565...240,405,627
Ensembl chr 1:240,298,563...240,402,448 		JBrowse link
G Lcorl ligand dependent nuclear receptor corepressor-like decreases expression ISO Vincristine results in decreased expression of LCORL mRNA CTD PMID:23649840 NCBI chr14:65,271,339...65,407,732
Ensembl chr14:65,271,135...65,404,174 		JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 increases expression ISO Vincristine results in increased expression of LCP2 mRNA CTD PMID:23649840 NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559 		JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 increases expression ISO Vincristine results in increased expression of LDLRAD4 mRNA CTD PMID:23649840 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 decreases expression ISO Vincristine results in decreased expression of LDLRAP1 mRNA CTD PMID:23649840 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601 		JBrowse link
G Leg1 liver enriched gene 1 increases expression ISO Vincristine results in increased expression of C6ORF58 mRNA CTD PMID:23649840 NCBI chr 1:28,799,902...28,816,230
Ensembl chr 1:28,799,902...28,815,993 		JBrowse link
G Leng8 leukocyte receptor cluster member 8 decreases expression ISO Vincristine results in decreased expression of LENG8 mRNA CTD PMID:23649840 NCBI chr 1:70,040,785...70,052,662
Ensembl chr 1:70,040,785...70,052,488 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Vincristine results in increased expression of LIF mRNA CTD PMID:23649840 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lima1 LIM domain and actin binding 1 increases expression ISO Vincristine results in increased expression of LIMA1 mRNA CTD PMID:23649840 NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473 		JBrowse link
G Lims1 LIM zinc finger domain containing 1 increases expression ISO Vincristine results in increased expression of LIMS1 mRNA CTD PMID:23649840 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500 		JBrowse link
G Lmna lamin A/C increases expression ISO Vincristine results in increased expression of LMNA mRNA CTD PMID:23649840 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Lnpep leucyl and cystinyl aminopeptidase increases expression ISO Vincristine results in increased expression of LNPEP mRNA CTD PMID:23649840 NCBI chr 1:58,258,642...58,355,532
Ensembl chr 1:58,258,642...58,354,544 		JBrowse link
G Lrba LPS responsive beige-like anchor protein decreases expression ISO Vincristine results in decreased expression of LRBA mRNA CTD PMID:23649840 NCBI chr 2:171,623,668...172,202,576
Ensembl chr 2:171,621,507...172,202,724 		JBrowse link
G Lrch3 leucine rich repeats and calponin homology domain containing 3 increases expression ISO Vincristine results in increased expression of LRCH3 mRNA CTD PMID:23649840 NCBI chr11:67,772,499...67,872,269
Ensembl chr11:67,772,506...67,872,264 		JBrowse link
G Lrp8 LDL receptor related protein 8 decreases expression ISO Vincristine results in decreased expression of LRP8 mRNA CTD PMID:23649840 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352 		JBrowse link
G Lrrc8c leucine rich repeat containing 8 VRAC subunit C decreases expression ISO Vincristine results in decreased expression of LRRC8C mRNA CTD PMID:23649840 NCBI chr14:4,223,901...4,315,590
Ensembl chr14:4,227,832...4,315,249 		JBrowse link
G Lrrcc1 leucine rich repeat and coiled-coil centrosomal protein 1 decreases expression ISO Vincristine results in decreased expression of LRRCC1 mRNA CTD PMID:23649840 NCBI chr 2:87,025,671...87,060,313
Ensembl chr 2:87,025,598...87,060,294 		JBrowse link
G Lrrfip1 LRR binding FLII interacting protein 1 decreases expression ISO Vincristine results in decreased expression of LRRFIP1 mRNA CTD PMID:23649840 NCBI chr 9:91,592,032...91,720,250
Ensembl chr 9:91,643,197...91,720,250 		JBrowse link
G Lta lymphotoxin alpha increases expression ISO Vincristine results in increased expression of LTA mRNA CTD PMID:23649840 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Lto1 LTO1 maturation factor of ABCE1 decreases expression ISO Vincristine results in decreased expression of LTO1 mRNA CTD PMID:23649840 NCBI chr 1:200,074,247...200,080,951
Ensembl chr 1:200,074,253...200,088,061 		JBrowse link
G Lum lumican decreases response to substance ISO LUM mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793 		JBrowse link
G Ly96 lymphocyte antigen 96 increases expression ISO Vincristine results in increased expression of LY96 mRNA CTD PMID:23649840 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386 		JBrowse link
G Lztfl1 leucine zipper transcription factor-like 1 decreases expression ISO Vincristine results in decreased expression of LZTFL1 mRNA CTD PMID:23649840 NCBI chr 8:123,344,085...123,360,245
Ensembl chr 8:123,344,925...123,360,192 		JBrowse link
G Lzts2 leucine zipper tumor suppressor 2 decreases expression ISO Vincristine results in decreased expression of LZTS2 mRNA CTD PMID:23649840 NCBI chr 1:243,876,665...243,888,489
Ensembl chr 1:243,880,022...243,888,423 		JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 increases expression ISO Vincristine results in increased expression of MACF1 mRNA CTD PMID:23649840 NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905 		JBrowse link
G Macir macrophage immunometabolism regulator decreases expression ISO Vincristine results in decreased expression of MACIR mRNA CTD PMID:23649840 NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Vincristine results in increased expression of MAFF mRNA CTD PMID:23649840 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Magt1 magnesium transporter 1 decreases expression ISO Vincristine results in decreased expression of MAGT1 mRNA CTD PMID:23649840 NCBI chr  X:71,038,489...71,079,704
Ensembl chr  X:71,038,489...71,079,699 		JBrowse link
G Man2a1 mannosidase, alpha, class 2A, member 1 decreases expression ISO Vincristine results in decreased expression of MAN2A1 mRNA CTD PMID:23649840 NCBI chr 9:104,252,001...104,408,349
Ensembl chr 9:104,252,001...104,408,349 		JBrowse link
G Manea mannosidase, endo-alpha decreases expression ISO Vincristine results in decreased expression of MANEA mRNA CTD PMID:23649840 NCBI chr 5:40,196,373...40,218,540
Ensembl chr 5:40,196,396...40,218,459 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions		 ISO
EXP		 Vincristine results in increased expression of MAP1LC3B mRNA
Quercetin inhibits the reaction [Vincristine results in increased expression of MAP1LC3B protein]		 CTD PMID:23649840 PMID:36808657 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 decreases expression ISO Vincristine results in decreased expression of MAP3K1 mRNA CTD PMID:23649840 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 decreases expression ISO Vincristine results in decreased expression of MAP3K7 mRNA CTD PMID:23649840 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases expression ISO Vincristine results in increased expression of MAP3K8 mRNA CTD PMID:23649840 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 increases expression ISO Vincristine results in increased expression of MAP4K4 mRNA CTD PMID:23649840 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapkbp1 mitogen activated protein kinase binding protein 1 increases expression ISO Vincristine results in increased expression of MAPKBP1 mRNA CTD PMID:23649840 NCBI chr 3:106,947,342...106,998,368
Ensembl chr 3:106,947,827...106,996,199 		JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 decreases localization
multiple interactions		 ISO Vincristine results in decreased localization of MAPRE1 protein
olesoxime inhibits the reaction [Vincristine results in decreased localization of MAPRE1 protein]		 CTD PMID:20417191 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983 		JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 multiple interactions
affects localization		 ISO olesoxime inhibits the reaction [Vincristine results in decreased localization of MAPRE3 protein]
Vincristine affects the localization of MAPRE3 protein		 CTD PMID:20417191 NCBI chr 6:25,513,800...25,558,876
Ensembl chr 6:25,513,800...25,558,881 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 increases expression ISO Vincristine results in increased expression of MARCHF7 mRNA CTD PMID:23649840 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate increases expression ISO Vincristine results in increased expression of MARCKS mRNA CTD PMID:23649840 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Mars1 methionyl-tRNA synthetase 1 decreases expression ISO Vincristine results in decreased expression of MARS1 mRNA CTD PMID:23649840 NCBI chr 7:63,121,142...63,138,550
Ensembl chr 7:63,121,142...63,138,495 		JBrowse link
G Mars2 methionyl-tRNA synthetase 2, mitochondrial decreases expression ISO Vincristine results in decreased expression of MARS2 mRNA CTD PMID:23649840 NCBI chr 9:56,720,408...56,729,991
Ensembl chr 9:56,720,983...56,723,820 		JBrowse link
G Matn2 matrilin 2 decreases response to substance ISO MATN2 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 7:65,494,996...65,644,613
Ensembl chr 7:65,494,834...65,645,113 		JBrowse link
G Matr3 matrin 3 decreases expression ISO Vincristine results in decreased expression of MATR3 mRNA CTD PMID:23649840 NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166 		JBrowse link
G Max MYC associated factor X decreases expression ISO Vincristine results in decreased expression of MAX mRNA CTD PMID:23649840 NCBI chr 6:95,636,859...95,662,204
Ensembl chr 6:95,636,858...95,662,137 		JBrowse link
G Mbd4 methyl-CpG binding domain 4 DNA glycosylase decreases expression ISO Vincristine results in decreased expression of MBD4 mRNA CTD PMID:23649840 NCBI chr 4:148,893,049...148,904,833
Ensembl chr 4:148,894,280...148,904,982 		JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 decreases expression ISO Vincristine results in decreased expression of MBNL3 mRNA CTD PMID:23649840 NCBI chr  X:130,641,942...130,737,179
Ensembl chr  X:130,648,538...130,737,056 		JBrowse link
G Mbtd1 mbt domain containing 1 increases expression ISO Vincristine results in increased expression of MBTD1 mRNA CTD PMID:23649840 NCBI chr10:78,839,140...78,895,413
Ensembl chr10:78,839,036...78,893,720 		JBrowse link
G Mccc2 methylcrotonyl-CoA carboxylase subunit 2 increases expression ISO Vincristine results in increased expression of MCCC2 mRNA CTD PMID:23649840 NCBI chr 2:31,304,927...31,375,978
Ensembl chr 2:31,304,932...31,375,972 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression ISO Vincristine results in increased expression of MCL1 mRNA CTD PMID:23649840 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mcm4 minichromosome maintenance complex component 4 decreases expression ISO Vincristine results in decreased expression of MCM4 mRNA CTD PMID:23649840 NCBI chr11:85,258,443...85,272,144
Ensembl chr11:85,258,443...85,272,144 		JBrowse link
G Mcmbp minichromosome maintenance complex binding protein increases expression ISO Vincristine results in increased expression of MCMBP mRNA CTD PMID:23649840 NCBI chr 1:183,270,598...183,316,975
Ensembl chr 1:183,271,980...183,316,975 		JBrowse link
G Mcoln2 mucolipin TRP cation channel 2 increases expression ISO Vincristine results in increased expression of MCOLN2 mRNA CTD PMID:23649840 NCBI chr 2:235,053,816...235,102,703
Ensembl chr 2:235,053,816...235,102,702 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression
decreases expression		 ISO Vincristine results in increased expression of MDM2 mRNA
Vincristine results in decreased expression of MDM2 mRNA		 CTD PMID:16001973 PMID:23649840 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mdn1 midasin AAA ATPase 1 increases expression ISO Vincristine results in increased expression of MDN1 mRNA CTD PMID:23649840 NCBI chr 5:47,055,435...47,190,426
Ensembl chr 5:47,055,447...47,186,332 		JBrowse link
G Med29 mediator complex subunit 29 decreases expression ISO Vincristine results in decreased expression of MED29 mRNA CTD PMID:23649840 NCBI chr 1:83,677,961...83,683,365
Ensembl chr 1:83,677,961...83,683,365 		JBrowse link
G Med31 mediator complex subunit 31 decreases expression ISO Vincristine results in decreased expression of MED31 mRNA CTD PMID:23649840 NCBI chr10:56,836,944...56,840,326
Ensembl chr10:56,836,944...56,840,326 		JBrowse link
G Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit decreases expression ISO Vincristine results in decreased expression of METTL3 mRNA CTD PMID:23649840 NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041 		JBrowse link
G Mfsd5 major facilitator superfamily domain containing 5 decreases expression ISO Vincristine results in decreased expression of MFSD5 mRNA CTD PMID:23649840 NCBI chr 7:133,409,096...133,411,377
Ensembl chr 7:133,402,537...133,411,396 		JBrowse link
G Mfsd6 major facilitator superfamily domain containing 6 decreases expression ISO Vincristine results in decreased expression of MFSD6 mRNA CTD PMID:23649840 NCBI chr 9:48,773,171...48,858,471
Ensembl chr 9:48,773,414...48,858,465 		JBrowse link
G Mga MAX dimerization protein MGA increases expression ISO Vincristine results in increased expression of MGA mRNA CTD PMID:23649840 NCBI chr 3:106,851,216...106,942,908
Ensembl chr 3:106,851,140...106,941,043 		JBrowse link
G Mgat4a alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A decreases expression ISO Vincristine results in decreased expression of MGAT4A mRNA CTD PMID:23649840 NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions ISO [MGMT protein co-treated with ABCB1 protein] results in decreased susceptibility to Vincristine; MGMT affects the susceptibility to [Procarbazine co-treated with Vincristine co-treated with Nitrosourea Compounds]; MGMT protein affects the susceptibility to [Procarbazine co-treated with Lomustine co-treated with Vincristine] CTD PMID:11792417 PMID:16033832 PMID:16936459 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mical3 microtubule associated monooxygenase, calponin and LIM domain containing 3 increases expression ISO Vincristine results in increased expression of MICAL3 mRNA CTD PMID:23649840 NCBI chr 4:154,152,776...154,353,274
Ensembl chr 4:154,153,834...154,302,590 		JBrowse link
G Mir132 microRNA 132 increases expression ISO Vincristine results in increased expression of MIR132 mRNA CTD PMID:32505695 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir497 microRNA 497 multiple interactions ISO [MIR497 results in decreased expression of BCL2 protein] which results in increased susceptibility to Vincristine CTD PMID:21258880 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases response to substance ISO MKI67 gene SNP results in increased susceptibility to Vincristine CTD PMID:20864405 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mkln1 muskelin 1 increases expression ISO Vincristine results in increased expression of MKLN1 mRNA CTD PMID:23649840 NCBI chr 4:59,815,912...60,124,047
Ensembl chr 4:60,002,464...60,123,993 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 increases expression ISO Vincristine results in increased expression of MKNK2 mRNA CTD PMID:23649840 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827 		JBrowse link
G Mllt3 MLLT3, super elongation complex subunit increases expression ISO Vincristine results in increased expression of MLLT3 mRNA CTD PMID:23649840 NCBI chr 5:102,259,075...102,515,447
Ensembl chr 5:102,260,011...102,515,361 		JBrowse link
G Mmd monocyte to macrophage differentiation-associated increases expression ISO Vincristine results in increased expression of MMD mRNA CTD PMID:23649840 NCBI chr10:75,073,278...75,101,528
Ensembl chr10:75,073,365...75,101,528 		JBrowse link
G Mnd1 meiotic nuclear divisions 1 decreases expression ISO Vincristine results in decreased expression of MND1 mRNA CTD PMID:23649840 NCBI chr 2:169,433,523...169,496,081
Ensembl chr 2:169,433,540...169,496,096 		JBrowse link
G Mpz myelin protein zero increases response to substance ISO MPZ gene results in increased susceptibility to Vincristine CTD PMID:16676325 NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679 		JBrowse link
G Mr1 major histocompatibility complex, class I-related increases expression ISO Vincristine results in increased expression of MR1 mRNA CTD PMID:23649840 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970 		JBrowse link
G Mrpl30 mitochondrial ribosomal protein L30 decreases expression ISO Vincristine results in decreased expression of MRPL30 mRNA CTD PMID:23649840 NCBI chr 9:40,125,352...40,136,189
Ensembl chr 9:40,125,430...40,137,257 		JBrowse link
G Mrpl39 mitochondrial ribosomal protein L39 decreases expression ISO Vincristine results in decreased expression of MRPL39 mRNA CTD PMID:23649840 NCBI chr11:23,779,655...23,795,146
Ensembl chr11:23,779,662...23,795,125 		JBrowse link
G Mrpl50 mitochondrial ribosomal protein L50 decreases expression ISO Vincristine results in decreased expression of MRPL50 mRNA CTD PMID:23649840 NCBI chr 5:63,867,437...63,872,591 JBrowse link
G Mrps16 mitochondrial ribosomal protein S16 decreases expression ISO Vincristine results in decreased expression of MRPS16 mRNA CTD PMID:23649840 NCBI chr15:3,918,621...3,921,024
Ensembl chr15:3,918,615...3,921,656 		JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 increases expression ISO Vincristine results in increased expression of ND6 mRNA CTD PMID:23649840 NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061 		JBrowse link
G Mt2-ps1 metallothionein 2, pseudogene 1 increases expression ISO Vincristine results in increased expression of MT1HL1 mRNA CTD PMID:23649840 NCBI chr20:3,159,037...3,159,409
Ensembl chr 5:119,728,811...119,730,073 		JBrowse link
G Mt2A metallothionein 2A increases expression ISO Vincristine results in increased expression of MT2A mRNA CTD PMID:23649840 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mta3 metastasis associated 1 family, member 3 decreases expression ISO Vincristine results in decreased expression of MTA3 mRNA CTD PMID:23649840 NCBI chr 6:10,867,028...10,987,221
Ensembl chr 6:10,867,011...10,986,883 		JBrowse link
G Mtcp1 mature T-cell proliferation 1 decreases expression ISO Vincristine results in decreased expression of MTCP1 mRNA CTD PMID:23649840 NCBI chr18:126,189...130,123 JBrowse link
G Mtfr2 mitochondrial fission regulator 2 decreases expression ISO Vincristine results in decreased expression of MTFR2 mRNA CTD PMID:23649840 NCBI chr 1:15,123,232...15,138,632
Ensembl chr 1:15,070,894...15,148,832 		JBrowse link
G Mtg2 mitochondrial ribosome-associated GTPase 2 increases expression ISO Vincristine results in increased expression of MTG2 mRNA CTD PMID:23649840 NCBI chr 3:167,165,542...167,181,358
Ensembl chr 3:167,165,982...167,181,358 		JBrowse link
G Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like decreases expression ISO Vincristine results in decreased expression of MTHFD2L mRNA CTD PMID:23649840 NCBI chr14:17,089,947...17,170,036
Ensembl chr14:17,089,952...17,170,112 		JBrowse link
G Mtrf1l mitochondrial translation release factor 1 like decreases expression ISO Vincristine results in decreased expression of MTRF1L mRNA CTD PMID:23649840 NCBI chr 1:42,208,553...42,221,020
Ensembl chr 1:42,210,583...42,220,836 		JBrowse link
G Mvp major vault protein increases expression ISO Vincristine results in increased expression of MVP mRNA CTD PMID:23649840 NCBI chr 1:181,594,734...181,622,336
Ensembl chr 1:181,594,734...181,622,380 		JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Vincristine results in increased expression of MXD1 mRNA CTD PMID:23649840 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
increases expression		 ISO
EXP		 Vincristine results in decreased expression of MYC mRNA
Vincristine results in increased expression of MYC mRNA		 CTD PMID:16001973 PMID:20624997 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases response to substance
multiple interactions		 ISO MYCN protein results in decreased susceptibility to Vincristine
[MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Vincristine		 CTD PMID:10348353 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590 		JBrowse link
G Myh11 myosin heavy chain 11 increases expression ISO Vincristine results in increased expression of MYH11 mRNA CTD PMID:23649840 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459 		JBrowse link
G Mysm1 myb-like, SWIRM and MPN domains 1 increases expression ISO Vincristine results in increased expression of MYSM1 mRNA CTD PMID:23649840 NCBI chr 5:109,761,345...109,826,652
Ensembl chr 5:109,776,286...109,819,967 		JBrowse link
G Mzb1 marginal zone B and B1 cell-specific protein decreases expression ISO Vincristine results in decreased expression of MZB1 mRNA CTD PMID:23649840 NCBI chr18:27,238,999...27,241,060
Ensembl chr18:27,239,001...27,241,094 		JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 increases expression ISO Vincristine results in increased expression of N4BP2L2 mRNA CTD PMID:23649840 NCBI chr12:137,342...200,292
Ensembl chr12:103,590...197,784 		JBrowse link
G Naa25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit decreases expression ISO Vincristine results in decreased expression of NAA25 mRNA CTD PMID:23649840 NCBI chr12:35,098,256...35,150,498
Ensembl chr12:35,098,075...35,150,467 		JBrowse link
G Naa50 N(alpha)-acetyltransferase 50, NatE catalytic subunit decreases expression ISO Vincristine results in decreased expression of NAA50 mRNA CTD PMID:23649840 NCBI chr11:56,538,366...56,560,842
Ensembl chr11:56,538,366...56,560,842 		JBrowse link
G Nabp1 nucleic acid binding protein 1 increases expression ISO Vincristine results in increased expression of NABP1 mRNA CTD PMID:23649840 NCBI chr 9:50,098,552...50,133,982
Ensembl chr 9:50,126,726...50,134,107 		JBrowse link
G Naca nascent polypeptide associated complex subunit alpha decreases expression ISO Vincristine results in decreased expression of NACA mRNA CTD PMID:23649840 NCBI chr 7:468,862...481,992
Ensembl chr 7:469,723...481,992 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression ISO Vincristine results in increased expression of NAMPT mRNA CTD PMID:23649840 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Napb NSF attachment protein beta increases expression ISO Vincristine results in increased expression of NAPB mRNA CTD PMID:23649840 NCBI chr 3:136,132,248...136,179,280
Ensembl chr 3:136,133,428...136,179,345 		JBrowse link
G Nasp nuclear autoantigenic sperm protein decreases expression ISO Vincristine results in decreased expression of NASP mRNA CTD PMID:23649840 NCBI chr 5:130,057,363...130,083,003
Ensembl chr 5:130,057,363...130,082,928 		JBrowse link
G Nbn nibrin increases expression EXP Vincristine results in increased expression of NBN mRNA CTD PMID:20624997 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 decreases expression ISO Vincristine results in decreased expression of NCBP1 mRNA CTD PMID:23649840 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089 		JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 increases expression ISO Vincristine results in increased expression of NCEH1 mRNA CTD PMID:23649840 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 increases expression ISO Vincristine results in increased expression of NCF2 mRNA CTD PMID:23649840 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Ncoa7 nuclear receptor coactivator 7 increases expression ISO Vincristine results in increased expression of NCOA7 mRNA CTD PMID:23649840 NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871 		JBrowse link
G Nde1 nudE neurodevelopment protein 1 increases expression ISO Vincristine results in increased expression of NDE1 mRNA CTD PMID:23649840 NCBI chr10:839,788...883,946
Ensembl chr10:839,788...883,869 		JBrowse link
G Ndufb4 NADH:ubiquinone oxidoreductase subunit B4 decreases expression ISO Vincristine results in decreased expression of NDUFB4 mRNA CTD PMID:23649840 NCBI chr11:63,063,723...63,070,426
Ensembl chr11:63,063,795...63,070,425 		JBrowse link
G Nefl neurofilament light chain increases expression
multiple interactions		 EXP Vincristine results in increased expression of NEFL protein
coenzyme Q10 inhibits the reaction [Vincristine results in increased expression of NEFL protein]		 CTD PMID:34939713 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Neurl3 neuralized E3 ubiquitin protein ligase 3 increases expression ISO Vincristine results in increased expression of NEURL3 mRNA CTD PMID:23649840 NCBI chr 9:38,494,486...38,503,352
Ensembl chr 9:38,494,489...38,502,649 		JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 increases expression ISO Vincristine results in increased expression of NFAT5 mRNA CTD PMID:23649840 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 increases response to substance ISO NFATC2 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325 		JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 increases expression ISO Vincristine results in increased expression of NFE2L1 mRNA CTD PMID:23649840 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression
multiple interactions		 EXP Vincristine results in decreased expression of NFE2L2 mRNA; Vincristine results in decreased expression of NFE2L2 protein
coenzyme Q10 inhibits the reaction [Vincristine results in decreased expression of NFE2L2 mRNA]; Quercetin inhibits the reaction [Vincristine results in decreased expression of NFE2L2 protein]		 CTD PMID:33038355 PMID:34939713 PMID:36808657 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfe2l3 NFE2 like bZIP transcription factor 3 decreases expression ISO Vincristine results in decreased expression of NFE2L3 mRNA CTD PMID:23649840 NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629 		JBrowse link
G Ngf nerve growth factor multiple interactions
decreases response to substance		 EXP Bicuculline inhibits the reaction [Propofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]; Bicuculline inhibits the reaction [Thiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]]; Propofol inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]; Thiopental inhibits the reaction [Vincristine results in decreased susceptibility to NGF protein]
NGF protein results in decreased susceptibility to Vincristine; Vincristine results in decreased susceptibility to NGF protein		 CTD PMID:9524088 PMID:9622663 PMID:10553948 PMID:11991087 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nhsl1 NHS-like 1 increases expression ISO Vincristine results in increased expression of NHSL1 mRNA CTD PMID:23649840 NCBI chr 1:12,956,525...13,188,580
Ensembl chr 1:12,956,021...13,187,547 		JBrowse link
G Ninj1 ninjurin 1 increases expression ISO Vincristine results in increased expression of NINJ1 mRNA CTD PMID:23649840 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Nisch nischarin decreases expression ISO Vincristine results in decreased expression of NISCH mRNA CTD PMID:23649840 NCBI chr16:6,364,370...6,400,675
Ensembl chr16:6,364,374...6,400,668 		JBrowse link
G Nmnat3 nicotinamide nucleotide adenylyltransferase 3 decreases response to substance ISO NMNAT3 protein results in decreased susceptibility to Vincristine CTD PMID:18463239 NCBI chr 8:98,892,168...99,003,912
Ensembl chr 8:98,873,398...99,020,645 		JBrowse link
G Nmrk2 nicotinamide riboside kinase 2 decreases response to substance ISO ITGB1BP3 mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 7:8,514,855...8,517,916
Ensembl chr 7:8,514,927...8,517,922 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase decreases expression ISO Vincristine results in decreased expression of NNT mRNA CTD PMID:23649840 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Nol12 nucleolar protein 12 decreases expression ISO Vincristine results in decreased expression of NOL12 mRNA CTD PMID:23649840 NCBI chr 7:110,493,294...110,498,908
Ensembl chr 7:110,493,246...110,498,907 		JBrowse link
G Nol4l nucleolar protein 4-like increases expression ISO Vincristine results in increased expression of NOL4L mRNA CTD PMID:23649840 NCBI chr 3:141,884,840...142,007,668
Ensembl chr 3:141,884,840...142,008,976 		JBrowse link
G Nos1 nitric oxide synthase 1 decreases expression ISO Vincristine results in decreased expression of NOS1 protein CTD PMID:16098672 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Npl N-acetylneuraminate pyruvate lyase increases expression ISO Vincristine results in increased expression of NPL mRNA CTD PMID:23649840 NCBI chr13:65,655,099...65,697,464
Ensembl chr13:65,655,118...65,697,372 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases activity
multiple interactions		 EXP Vincristine results in decreased activity of NQO1 protein
Quercetin inhibits the reaction [Vincristine results in decreased activity of NQO1 protein]		 CTD PMID:33038355 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Vincristine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity		 ISO [Vincristine results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 mRNA; NR1I2 protein promotes the reaction [Vincristine results in increased expression of ABCB1 protein] CTD PMID:20041327 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 decreases expression ISO Vincristine results in decreased expression of NR2F2 mRNA CTD PMID:23649840 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression ISO Vincristine results in increased expression of NR5A2 mRNA CTD PMID:23649840 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO Vincristine results in decreased expression of NREP mRNA CTD PMID:23649840 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591 		JBrowse link
G Nrn1 neuritin 1 decreases expression ISO Vincristine results in decreased expression of NRN1 mRNA CTD PMID:23649840 NCBI chr17:28,129,969...28,138,898
Ensembl chr17:28,129,977...28,138,896 		JBrowse link
G Nsmce4a NSE4 homolog A, SMC5-SMC6 complex component decreases expression ISO Vincristine results in decreased expression of NSMCE4A mRNA CTD PMID:23649840 NCBI chr 1:185,102,075...185,109,166
Ensembl chr 1:185,094,360...185,109,166 		JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression ISO Vincristine results in increased expression of NT5E mRNA CTD PMID:23649840 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Nudt7 nudix hydrolase 7 decreases expression ISO Vincristine results in decreased expression of NUDT7 mRNA CTD PMID:23649840 NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex increases expression ISO Vincristine results in increased expression of NUF2 mRNA CTD PMID:23649840 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766 		JBrowse link
G Numb NUMB, endocytic adaptor protein increases expression ISO Vincristine results in increased expression of NUMB mRNA CTD PMID:23649840 NCBI chr 6:103,431,400...103,553,422
Ensembl chr 6:103,431,400...103,553,354 		JBrowse link
G Nup153 nucleoporin 153 increases expression ISO Vincristine results in increased expression of NUP153 mRNA CTD PMID:23649840 NCBI chr17:17,972,217...18,024,876
Ensembl chr17:17,972,217...18,024,876 		JBrowse link
G Nxt1 nuclear transport factor 2-like export factor 1 decreases expression ISO Vincristine results in decreased expression of NXT1 mRNA CTD PMID:23649840 NCBI chr 3:136,108,975...136,111,897
Ensembl chr 3:136,108,862...136,111,907 		JBrowse link
G Oga O-GlcNAcase increases expression ISO Vincristine results in increased expression of OGA mRNA CTD PMID:23649840 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase decreases expression ISO Vincristine results in decreased expression of OGG1 mRNA CTD PMID:23649840 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase decreases expression ISO Vincristine results in decreased expression of OGT mRNA CTD PMID:23649840 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Olah oleoyl-ACP hydrolase increases expression ISO Vincristine results in increased expression of OLAH mRNA CTD PMID:23649840 NCBI chr17:74,877,651...74,902,517
Ensembl chr17:74,877,655...74,902,518 		JBrowse link
G Orai1 ORAI calcium release-activated calcium modulator 1 decreases expression ISO Vincristine results in decreased expression of ORAI1 mRNA CTD PMID:23649840 NCBI chr12:33,533,151...33,548,361
Ensembl chr12:33,534,344...33,548,405 		JBrowse link
G Otp orthopedia homeobox increases expression ISO Vincristine results in increased expression of OTP mRNA CTD PMID:23649840 NCBI chr 2:26,108,158...26,116,359
Ensembl chr 2:26,108,163...26,116,359 		JBrowse link
G Oxtr oxytocin receptor affects response to substance ISO OXTR protein affects the susceptibility to Vincristine CTD PMID:33429010 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674 		JBrowse link
G P2rx5 purinergic receptor P2X 5 decreases expression ISO Vincristine results in decreased expression of P2RX5 mRNA CTD PMID:23649840 NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423 		JBrowse link
G P2rx7 purinergic receptor P2X 7 multiple interactions EXP [(N-(1-(((cyanoimino)(5-quinolinylamino) methyl) amino)-2,2-dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide) binds to and results in decreased activity of P2RX7 protein] which results in decreased susceptibility to Vincristine CTD PMID:16982702 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 decreases expression ISO Vincristine results in decreased expression of P4HA1 mRNA CTD PMID:23649840 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786 		JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like decreases expression ISO Vincristine results in decreased expression of PABPC1L mRNA CTD PMID:23649840 NCBI chr 3:152,692,825...152,725,997
Ensembl chr 3:152,693,700...152,725,997 		JBrowse link
G Pabpn1 poly(A) binding protein, nuclear 1 decreases expression ISO Vincristine results in decreased expression of PABPN1 mRNA CTD PMID:23649840 NCBI chr15:28,368,100...28,372,712
Ensembl chr15:28,368,100...28,372,703 		JBrowse link
G Paip1 poly(A) binding protein interacting protein 1 decreases expression ISO Vincristine results in decreased expression of PAIP1 mRNA CTD PMID:23649840 NCBI chr 2:51,523,190...51,550,241
Ensembl chr 2:51,522,921...51,550,241 		JBrowse link
G Pank2 pantothenate kinase 2 decreases expression ISO Vincristine results in decreased expression of PANK2 mRNA CTD PMID:23649840 NCBI chr 3:118,483,382...118,519,551
Ensembl chr 3:118,483,444...118,518,320 		JBrowse link
G Paqr4 progestin and adipoQ receptor family member 4 decreases expression ISO Vincristine results in decreased expression of PAQR4 mRNA CTD PMID:23649840 NCBI chr10:12,758,970...12,762,649
Ensembl chr10:12,758,972...12,762,584 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [CEP 33779 results in increased susceptibility to Vincristine] which results in increased cleavage of PARP1 protein; [NVP-BSK805 results in increased susceptibility to Vincristine] which results in increased cleavage of PARP1 protein CTD PMID:28669723 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 decreases expression ISO Vincristine results in decreased expression of PARP2 mRNA CTD PMID:23649840 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338 		JBrowse link
G Parp9 poly (ADP-ribose) polymerase family, member 9 increases expression ISO Vincristine results in increased expression of PARP9 mRNA CTD PMID:23649840 NCBI chr11:64,780,977...64,814,995
Ensembl chr11:64,780,981...64,815,455 		JBrowse link
G Patl1 PAT1 homolog 1, processing body mRNA decay factor decreases expression ISO Vincristine results in decreased expression of PATL1 mRNA CTD PMID:23649840 NCBI chr 1:208,831,115...208,862,904
Ensembl chr 1:208,831,115...208,862,857 		JBrowse link
G Pbxip1 PBX homeobox interacting protein 1 increases expression ISO Vincristine results in increased expression of PBXIP1 mRNA CTD PMID:23649840 NCBI chr 2:174,856,339...174,868,922
Ensembl chr 2:174,856,397...174,868,919 		JBrowse link
G Pced1b PC-esterase domain containing 1B decreases expression ISO Vincristine results in decreased expression of PCED1B mRNA CTD PMID:23649840 NCBI chr 7:128,394,388...128,528,231
Ensembl chr 7:128,391,319...128,528,231 		JBrowse link
G Pcf11 PCF11 cleavage and polyadenylation factor subunit decreases expression ISO Vincristine results in decreased expression of PCF11 mRNA CTD PMID:23649840 NCBI chr 1:146,694,045...146,724,030
Ensembl chr 1:146,697,646...146,724,124 		JBrowse link
G Pcgf2 polycomb group ring finger 2 decreases expression ISO Vincristine results in decreased expression of PCGF2 mRNA CTD PMID:23649840 NCBI chr10:82,682,563...82,694,563
Ensembl chr10:82,683,553...82,693,406 		JBrowse link
G Pcnx1 pecanex 1 increases expression ISO Vincristine results in increased expression of PCNX1 mRNA CTD PMID:23649840 NCBI chr 6:101,565,461...101,702,339
Ensembl chr 6:101,565,580...101,702,271 		JBrowse link
G Pcnx2 pecanex 2 increases expression ISO Vincristine results in increased expression of PCNX2 mRNA CTD PMID:23649840 NCBI chr19:53,718,920...53,869,559
Ensembl chr19:53,718,655...53,871,364 		JBrowse link
G Pcsk7 proprotein convertase subtilisin/kexin type 7 increases expression ISO Vincristine results in increased expression of PCSK7 mRNA CTD PMID:23649840 NCBI chr 8:46,202,079...46,224,699
Ensembl chr 8:46,202,131...46,224,705 		JBrowse link
G Pdcd5 programmed cell death 5 decreases expression ISO Vincristine results in decreased expression of PDCD5 mRNA CTD PMID:23649840 NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200 		JBrowse link
G Pde4b phosphodiesterase 4B increases expression ISO Vincristine results in increased expression of PDE4B mRNA CTD PMID:23649840 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 decreases expression ISO Vincristine results in decreased expression of PDK1 mRNA CTD PMID:23649840 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdk3 pyruvate dehydrogenase kinase 3 decreases expression ISO Vincristine results in decreased expression of PDK3 mRNA CTD PMID:23649840 NCBI chr  X:58,486,699...58,553,533
Ensembl chr  X:58,486,554...58,553,557 		JBrowse link
G Pds5b PDS5 cohesin associated factor B increases expression ISO Vincristine results in increased expression of PDS5B mRNA CTD PMID:23649840 NCBI chr12:202,481...345,596
Ensembl chr12:255,313...345,596 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 increases expression ISO Vincristine results in increased expression of PEA15 mRNA CTD PMID:23649840 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499 		JBrowse link
G Peli1 pellino E3 ubiquitin protein ligase 1 decreases expression ISO Vincristine results in decreased expression of PELI1 mRNA CTD PMID:23649840 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Pex11b peroxisomal biogenesis factor 11 beta decreases expression ISO Vincristine results in decreased expression of PEX11B mRNA CTD PMID:23649840 NCBI chr 2:184,172,041...184,180,972
Ensembl chr 2:184,172,004...184,181,495 		JBrowse link
G Pex13 peroxisomal biogenesis factor 13 decreases expression ISO Vincristine results in decreased expression of PEX13 mRNA CTD PMID:23649840 NCBI chr14:97,602,829...97,621,233
Ensembl chr14:97,603,539...97,621,262 		JBrowse link
G Pfas phosphoribosylformylglycinamidine synthase decreases expression ISO Vincristine results in decreased expression of PFAS mRNA CTD PMID:23649840 NCBI chr10:53,690,301...53,711,811
Ensembl chr10:53,691,626...53,708,420 		JBrowse link
G Pfkfb4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 decreases expression ISO Vincristine results in decreased expression of PFKFB4 mRNA CTD PMID:23649840 NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634 		JBrowse link
G Pgm1 phosphoglucomutase 1 decreases expression ISO Vincristine results in decreased expression of PGM1 mRNA CTD PMID:23649840 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728 		JBrowse link
G Pgp phosphoglycolate phosphatase decreases expression ISO Vincristine results in decreased expression of PGP mRNA CTD PMID:23649840 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858 		JBrowse link
G Phf11 PHD finger protein 11 increases expression ISO Vincristine results in increased expression of PHF11 mRNA CTD PMID:23649840 NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009 		JBrowse link
G Phf6 PHD finger protein 6 decreases expression ISO Vincristine results in decreased expression of PHF6 mRNA CTD PMID:23649840 NCBI chr  X:132,656,658...132,699,720
Ensembl chr  X:132,656,672...132,699,127 		JBrowse link
G Phtf2 putative homeodomain transcription factor 2 decreases expression ISO Vincristine results in decreased expression of PHTF2 mRNA CTD PMID:23649840 NCBI chr 4:14,215,190...14,330,549
Ensembl chr 4:14,215,263...14,330,513 		JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha increases expression ISO Vincristine results in increased expression of PIK3C2A mRNA CTD PMID:23649840 NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases phosphorylation
multiple interactions		 ISO Vincristine results in decreased phosphorylation of PIK3R1 protein
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Vincristine results in decreased phosphorylation of PIK3R1 protein]; bisphenol A inhibits the reaction [Vincristine results in decreased phosphorylation of PIK3R1 protein]; perfluorooctanoic acid inhibits the reaction [Vincristine results in decreased phosphorylation of PIK3R1 protein]		 CTD PMID:36181250 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 decreases expression ISO Vincristine results in decreased expression of PIK3R2 mRNA CTD PMID:23649840 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065 		JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha increases expression ISO Vincristine results in increased expression of PILRA mRNA CTD PMID:23649840 NCBI chr12:17,787,169...17,798,149
Ensembl chr12:17,787,127...17,798,094 		JBrowse link
G Pim2 Pim-2 proto-oncogene, serine/threonine kinase increases expression ISO Vincristine results in increased expression of PIM2 mRNA CTD PMID:23649840 NCBI chr  X:14,617,582...14,622,851
Ensembl chr  X:14,617,582...14,622,851 		JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta decreases expression ISO Vincristine results in decreased expression of PITPNB mRNA CTD PMID:23649840 NCBI chr12:45,249,308...45,298,388
Ensembl chr12:45,249,333...45,298,314 		JBrowse link
G Pkig cAMP-dependent protein kinase inhibitor gamma increases expression ISO Vincristine results in increased expression of PKIG mRNA CTD PMID:23649840 NCBI chr 3:152,330,477...152,398,085
Ensembl chr 3:152,366,041...152,398,082 		JBrowse link
G Pla1a phospholipase A1 member A increases expression ISO Vincristine results in increased expression of PLA1A mRNA CTD PMID:23649840 NCBI chr11:62,320,112...62,357,779
Ensembl chr11:62,320,493...62,357,779 		JBrowse link
G Pla2g4c phospholipase A2 group IVC increases expression ISO Vincristine results in increased expression of PLA2G4C mRNA CTD PMID:23649840 NCBI chr 1:74,237,714...74,275,757
Ensembl chr 1:74,236,211...74,274,656 		JBrowse link
G Plat plasminogen activator, tissue type increases expression EXP Vincristine results in increased expression of PLAT mRNA CTD PMID:20624997 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression EXP Vincristine results in increased expression of PLAUR mRNA CTD PMID:20624997 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Plcxd1 phosphatidylinositol-specific phospholipase C, X domain containing 1 decreases expression ISO Vincristine results in decreased expression of PLCXD1 mRNA CTD PMID:23649840 NCBI chr12:46,578,917...46,582,181
Ensembl chr12:46,579,225...46,582,392 		JBrowse link
G Plek pleckstrin increases expression ISO Vincristine results in increased expression of PLEK mRNA CTD PMID:23649840 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131 		JBrowse link
G Plekha2 pleckstrin homology domain containing A2 decreases expression ISO Vincristine results in decreased expression of PLEKHA2 mRNA CTD PMID:23649840 NCBI chr16:66,938,684...67,000,661
Ensembl chr16:66,939,109...66,999,395 		JBrowse link
G Plekhg1 pleckstrin homology and RhoGEF domain containing G1 increases expression ISO Vincristine results in increased expression of PLEKHG1 mRNA CTD PMID:23649840 NCBI chr 1:40,348,684...40,434,063
Ensembl chr 1:40,311,221...40,434,063 		JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression ISO Vincristine results in increased expression of PLPP3 mRNA CTD PMID:23649840 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205 		JBrowse link
G Pm20d2 peptidase M20 domain containing 2 decreases expression ISO Vincristine results in decreased expression of PM20D2 mRNA CTD PMID:23649840 NCBI chr 5:47,566,059...47,586,334
Ensembl chr 5:47,566,072...47,586,212 		JBrowse link
G Pmp22 peripheral myelin protein 22 increases response to substance ISO PMP22 gene mutant form results in increased susceptibility to Vincristine CTD PMID:12427913 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component decreases expression ISO Vincristine results in decreased expression of PMS1 mRNA CTD PMID:23649840 NCBI chr 9:48,229,403...48,340,237
Ensembl chr 9:48,253,410...48,340,237 		JBrowse link
G Pnisr PNN interacting serine and arginine rich protein decreases expression ISO Vincristine results in decreased expression of PNISR mRNA CTD PMID:23649840 NCBI chr 5:35,395,965...35,422,852
Ensembl chr 5:35,395,965...35,422,844 		JBrowse link
G Pnoc prepronociceptin decreases expression ISO Vincristine results in decreased expression of PNOC mRNA CTD PMID:23649840 NCBI chr15:39,624,635...39,652,463
Ensembl chr15:39,624,641...39,651,867 		JBrowse link
G Poglut1 protein O-glucosyltransferase 1 increases expression ISO Vincristine results in increased expression of POGLUT1 mRNA CTD PMID:23649840 NCBI chr11:62,198,600...62,226,446
Ensembl chr11:62,198,513...62,226,434 		JBrowse link
G Pogz pogo transposable element derived with ZNF domain increases expression ISO Vincristine results in increased expression of POGZ mRNA CTD PMID:23649840 NCBI chr 2:182,394,269...182,440,711
Ensembl chr 2:182,380,768...182,440,707 		JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO Vincristine results in decreased expression of POLA1 mRNA CTD PMID:23649840 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pold3 DNA polymerase delta 3, accessory subunit decreases expression ISO Vincristine results in decreased expression of POLD3 mRNA CTD PMID:23649840 NCBI chr 1:154,417,893...154,456,687
Ensembl chr 1:154,418,084...154,456,665 		JBrowse link
G Polq DNA polymerase theta increases expression ISO Vincristine results in increased expression of POLQ mRNA CTD PMID:23649840 NCBI chr11:63,673,796...63,775,905
Ensembl chr11:63,673,816...63,775,878 		JBrowse link
G Polr1b RNA polymerase I subunit B decreases expression ISO Vincristine results in decreased expression of POLR1B mRNA CTD PMID:23649840 NCBI chr 3:116,333,910...116,358,385
Ensembl chr 3:116,333,889...116,358,379 		JBrowse link
G Polr1h RNA polymerase I subunit H decreases response to substance
multiple interactions		 ISO POLR1H protein results in decreased susceptibility to Vincristine
Verapamil inhibits the reaction [POLR1H protein results in decreased susceptibility to Vincristine]		 CTD PMID:14726695 NCBI chr20:1,594,936...1,598,854
Ensembl chr20:1,594,936...1,598,854 		JBrowse link
G Postn periostin decreases response to substance ISO POSTN mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
G Pou2af1 POU class 2 homeobox associating factor 1 decreases expression ISO Vincristine results in decreased expression of POU2AF1 mRNA CTD PMID:23649840 NCBI chr 8:51,521,813...51,548,819
Ensembl chr 8:51,474,015...51,548,819 		JBrowse link
G Pou2f1 POU class 2 homeobox 1 decreases expression ISO Vincristine results in decreased expression of POU2F1 mRNA CTD PMID:23649840 NCBI chr13:78,120,617...78,263,306
Ensembl chr13:78,130,685...78,263,363 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression
multiple interactions		 EXP Vincristine results in decreased expression of PPARGC1A protein
Quercetin inhibits the reaction [Vincristine results in decreased expression of PPARGC1A protein]		 CTD PMID:36808657 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A increases expression ISO Vincristine results in increased expression of PPM1A mRNA CTD PMID:23649840 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 increases expression ISO Vincristine results in increased expression of PPP1R10 mRNA CTD PMID:23649840 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP
ISO		 Vincristine results in increased expression of PPP1R15A mRNA CTD PMID:20624997 PMID:23649840 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B increases response to substance ISO PPP1R1B protein results in increased susceptibility to Vincristine CTD PMID:17470401 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Ppp1r3e protein phosphatase 1, regulatory subunit 3E decreases expression ISO Vincristine results in decreased expression of PPP1R3E mRNA CTD PMID:23649840 NCBI chr15:28,348,443...28,349,603
Ensembl chr15:28,347,854...28,349,603 		JBrowse link
G Ppp4r3b protein phosphatase 4, regulatory subunit 3B decreases expression ISO Vincristine results in decreased expression of PPP4R3B mRNA CTD PMID:23649840 NCBI chr14:102,917,043...102,965,210
Ensembl chr14:102,917,443...103,068,192 		JBrowse link
G Prc1 protein regulator of cytokinesis 1 increases expression ISO Vincristine results in increased expression of PRC1 mRNA CTD PMID:17374387 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765 		JBrowse link
G Prim1 DNA primase subunit 1 decreases expression ISO Vincristine results in decreased expression of PRIM1 mRNA CTD PMID:23649840 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526 		JBrowse link
G Prkcd protein kinase C, delta affects localization ISO Vincristine affects the localization of PRKCD protein CTD PMID:9852137 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkce protein kinase C, epsilon increases response to substance EXP PRKCE protein results in increased susceptibility to Vincristine CTD PMID:12809704 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit increases expression ISO Vincristine results in increased expression of PRKDC mRNA CTD PMID:23649840 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prlr prolactin receptor increases expression ISO Vincristine results in increased expression of PRLR mRNA CTD PMID:23649840 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Prnp prion protein decreases response to substance ISO PRNP protein results in decreased susceptibility to Vincristine CTD PMID:15386405 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937 		JBrowse link
G Prpf4b pre-mRNA processing factor 4B decreases expression ISO Vincristine results in decreased expression of PRP4K mRNA CTD PMID:23649840 NCBI chr17:29,985,343...30,020,285
Ensembl chr17:29,985,343...30,019,625 		JBrowse link
G Prr12 proline rich 12 decreases expression ISO Vincristine results in decreased expression of PRR12 mRNA CTD PMID:23649840 NCBI chr 1:95,510,015...95,534,002
Ensembl chr 1:95,509,931...95,533,652 		JBrowse link
G Prr3 proline rich 3 decreases expression ISO Vincristine results in decreased expression of PRR3 mRNA CTD PMID:23649840 NCBI chr20:2,792,868...2,799,865
Ensembl chr20:2,792,860...2,799,865 		JBrowse link
G Prrg4 proline rich and Gla domain 4 increases expression ISO Vincristine results in increased expression of PRRG4 mRNA CTD PMID:23649840 NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273 		JBrowse link
G Psd3 pleckstrin and Sec7 domain containing 3 increases expression ISO Vincristine results in increased expression of PSD3 mRNA CTD PMID:23649840 NCBI chr16:21,465,643...22,035,846
Ensembl chr16:21,465,639...22,034,547 		JBrowse link
G Psme4 proteasome activator subunit 4 increases expression ISO Vincristine results in increased expression of PSME4 mRNA CTD PMID:23649840 NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408 		JBrowse link
G Psmg4 proteasome assembly chaperone 4 increases expression ISO Vincristine results in increased expression of PSMG4 mRNA CTD PMID:23649840 NCBI chr17:30,710,682...30,718,035
Ensembl chr17:30,710,682...30,718,082 		JBrowse link
G Pspc1 paraspeckle component 1 decreases expression ISO Vincristine results in decreased expression of PSPC1 mRNA CTD PMID:23649840 NCBI chr15:30,828,617...30,911,315
Ensembl chr15:30,828,626...30,911,202 		JBrowse link
G Ptafr platelet-activating factor receptor increases expression ISO Vincristine results in increased expression of PTAFR mRNA CTD PMID:23649840 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Ptger4 prostaglandin E receptor 4 increases expression ISO Vincristine results in increased expression of PTGER4 mRNA CTD PMID:23649840 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptgr2 prostaglandin reductase 2 decreases expression ISO Vincristine results in decreased expression of PTGR2 mRNA CTD PMID:23649840 NCBI chr 6:103,931,367...103,963,113
Ensembl chr 6:103,931,409...103,963,111 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 ISO Vincristine results in increased expression of PTGS2 mRNA; Vincristine results in increased expression of PTGS2 protein
KN 93 inhibits the reaction [Vincristine results in increased expression of PTGS2 mRNA]; KN 93 inhibits the reaction [Vincristine results in increased expression of PTGS2 protein]		 CTD PMID:34286406 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta increases phosphorylation ISO Vincristine results in increased phosphorylation of PTK2B protein CTD PMID:11478917 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 decreases expression ISO Vincristine results in decreased expression of PTPN11 mRNA CTD PMID:23649840 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 increases expression ISO Vincristine results in increased expression of PTPN13 mRNA CTD PMID:23649840 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 increases expression ISO Vincristine results in increased expression of PTPN3 mRNA CTD PMID:23649840 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443 		JBrowse link
G Ptprk protein tyrosine phosphatase, receptor type, K increases expression ISO Vincristine results in increased expression of PTPRK mRNA CTD PMID:23649840 NCBI chr 1:16,738,896...17,236,687
Ensembl chr 1:16,850,576...17,103,605 		JBrowse link
G Ptpro protein tyrosine phosphatase, receptor type, O increases expression ISO Vincristine results in increased expression of PTPRO mRNA CTD PMID:23649840 NCBI chr 4:170,164,071...170,374,790
Ensembl chr 4:170,164,431...170,374,771 		JBrowse link
G Ptprr protein tyrosine phosphatase, receptor type, R increases expression ISO Vincristine results in increased expression of PTPRR mRNA CTD PMID:23649840 NCBI chr 7:51,662,595...51,929,605
Ensembl chr 7:51,662,595...51,929,603 		JBrowse link
G Pvrig PVR related immunoglobulin domain containing decreases expression ISO Vincristine results in decreased expression of PVRIG mRNA CTD PMID:23649840 NCBI chr12:17,363,721...17,365,577
Ensembl chr12:17,364,080...17,365,280 		JBrowse link
G Pxt1 peroxisomal testis enriched protein 1 increases expression ISO Vincristine results in increased expression of PXT1 mRNA CTD PMID:23649840 NCBI chr20:7,002,270...7,005,296
Ensembl chr20:7,002,271...7,006,780 		JBrowse link
G Qrich1 glutamine-rich 1 increases phosphorylation ISO Vincristine results in increased phosphorylation of QRICH1 protein CTD PMID:17510977 NCBI chr 8:109,216,900...109,256,472
Ensembl chr 8:109,217,376...109,261,359 		JBrowse link
G Rab11fip1 RAB11 family interacting protein 1 increases expression ISO Vincristine results in increased expression of RAB11FIP1 mRNA CTD PMID:23649840 NCBI chr16:64,886,902...64,917,491
Ensembl chr16:64,884,676...64,917,491 		JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 increases expression ISO Vincristine results in increased expression of RAB11FIP3 mRNA CTD PMID:23649840 NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
G Rab12 RAB12, member RAS oncogene family increases expression ISO Vincristine results in increased expression of RAB12 mRNA CTD PMID:23649840 NCBI chr 9:106,480,301...106,506,895
Ensembl chr 9:106,480,301...106,506,910 		JBrowse link
G Rab20 RAB20, member RAS oncogene family decreases expression ISO Vincristine results in decreased expression of RAB20 mRNA CTD PMID:23649840 NCBI chr16:78,019,337...78,043,529
Ensembl chr16:78,019,337...78,043,529 		JBrowse link
G Rab21 RAB21, member RAS oncogene family increases expression ISO Vincristine results in increased expression of RAB21 mRNA CTD PMID:23649840 NCBI chr 7:50,904,050...50,928,890
Ensembl chr 7:50,904,057...50,928,839 		JBrowse link
G Rab29 RAB29, member RAS oncogene family increases expression ISO Vincristine results in increased expression of RAB29 mRNA CTD PMID:23649840 NCBI chr13:43,307,757...43,313,420
Ensembl chr13:43,307,775...43,313,417 		JBrowse link
G Rab8b RAB8B, member RAS oncogene family increases expression ISO Vincristine results in increased expression of RAB8B mRNA CTD PMID:23649840 NCBI chr 8:67,458,921...67,536,466
Ensembl chr 8:67,458,923...67,536,384 		JBrowse link
G Rab9a RAB9A, member RAS oncogene family increases expression ISO Vincristine results in increased expression of RAB9A mRNA CTD PMID:23649840 NCBI chr  X:27,955,552...28,009,870
Ensembl chr  X:27,952,204...28,001,622 		JBrowse link
G Rabggtb Rab geranylgeranyltransferase subunit beta decreases expression ISO Vincristine results in decreased expression of RABGGTB mRNA CTD PMID:23649840 NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050 		JBrowse link
G Rabif RAB interacting factor decreases expression ISO Vincristine results in decreased expression of RABIF mRNA CTD PMID:23649840 NCBI chr13:45,936,371...45,948,929
Ensembl chr13:45,936,369...45,949,775 		JBrowse link
G Rac2 Rac family small GTPase 2 affects response to substance ISO RAC2 protein affects the susceptibility to Vincristine CTD PMID:19783987 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO Vincristine results in decreased expression of RACK1 mRNA CTD PMID:23649840 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Rad54l RAD54 like decreases expression ISO Vincristine results in decreased expression of RAD54L mRNA CTD PMID:23649840 NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070 		JBrowse link
G Ralgdsl1 ral guanine nucleotide dissociation stimulator like 1 increases expression ISO Vincristine results in increased expression of RGL1 mRNA CTD PMID:23649840 NCBI chr13:64,634,489...64,904,170
Ensembl chr13:64,635,246...64,904,191 		JBrowse link
G Rasef RAS and EF hand domain containing increases expression ISO Vincristine results in increased expression of RASEF mRNA CTD PMID:23649840 NCBI chr 5:87,548,908...87,619,286
Ensembl chr 5:87,548,908...87,619,031 		JBrowse link
G Rassf1 Ras association domain family member 1 increases expression EXP Vincristine results in increased expression of RASSF1 mRNA CTD PMID:20624997 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rassf4 Ras association domain family member 4 increases expression ISO Vincristine results in increased expression of RASSF4 mRNA CTD PMID:23649840 NCBI chr 4:149,897,525...149,932,658
Ensembl chr 4:149,897,543...149,932,411 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions ISO [CEP 33779 results in increased susceptibility to Vincristine] which results in increased phosphorylation of RB1 protein; [NVP-BSK805 results in increased susceptibility to Vincristine] which results in increased phosphorylation of RB1 protein; [XL019 compound co-treated with Vincristine] results in increased expression of and results in increased phosphorylation of RB1 protein modified form CTD PMID:28669723 PMID:29187454 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor increases expression ISO Vincristine results in increased expression of RBBP4 mRNA CTD PMID:23649840 NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284 		JBrowse link
G Rbbp8 RB binding protein 8, endonuclease decreases expression ISO Vincristine results in decreased expression of RBBP8 mRNA CTD PMID:23649840 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846 		JBrowse link
G Rbl1 RB transcriptional corepressor like 1 decreases expression ISO Vincristine results in decreased expression of RBL1 mRNA CTD PMID:23649840 NCBI chr 3:145,806,160...145,869,434
Ensembl chr 3:145,807,095...145,869,330 		JBrowse link
G Rbm12 RNA binding motif protein 12 decreases expression ISO Vincristine results in decreased expression of RBM12 mRNA CTD PMID:23649840 NCBI chr 3:144,609,661...144,629,911
Ensembl chr 3:144,611,623...144,629,915
Ensembl chr 3:144,611,623...144,629,915 		JBrowse link
G Rbm15 RNA binding motif protein 15 decreases expression ISO Vincristine results in decreased expression of RBM15 mRNA CTD PMID:23649840 NCBI chr 2:194,945,974...194,954,498
Ensembl chr 2:194,945,974...194,954,703 		JBrowse link
G Rbm17 RNA binding motif protein 17 decreases response to substance ISO RBM17 protein results in decreased susceptibility to Vincristine CTD PMID:16061639 NCBI chr17:66,937,140...66,954,034
Ensembl chr17:66,937,140...66,954,014 		JBrowse link
G Rbm18 RNA binding motif protein 18 increases expression ISO Vincristine results in increased expression of RBM18 mRNA CTD PMID:23649840 NCBI chr 3:19,467,333...19,487,171
Ensembl chr 3:19,467,335...19,487,178 		JBrowse link
G Rbm25 RNA binding motif protein 25 decreases expression ISO Vincristine results in decreased expression of RBM25 mRNA CTD PMID:23649840 NCBI chr 6:103,271,775...103,319,090
Ensembl chr 6:103,271,801...103,317,854 		JBrowse link
G Rbm4b RNA binding motif protein 4B decreases expression ISO Vincristine results in decreased expression of RBM4B mRNA CTD PMID:23649840 NCBI chr 1:202,047,934...202,058,025
Ensembl chr 1:202,047,927...202,058,020 		JBrowse link
G Rbm5 RNA binding motif protein 5 decreases expression ISO Vincristine results in decreased expression of RBM5 mRNA CTD PMID:23649840 NCBI chr 8:108,420,220...108,449,481
Ensembl chr 8:108,420,222...108,449,430 		JBrowse link
G Rbm6 RNA binding motif protein 6 decreases expression ISO Vincristine results in decreased expression of RBM6 mRNA CTD PMID:23649840 NCBI chr 8:108,452,687...108,552,783
Ensembl chr 8:108,452,687...108,552,771 		JBrowse link
G Rbm8a RNA binding motif protein 8A decreases expression ISO Vincristine results in decreased expression of RBM8A mRNA CTD PMID:23649840 NCBI chr 2:184,165,189...184,167,959
Ensembl chr 2:184,165,193...184,167,959 		JBrowse link
G Rcc1l RCC1 like increases expression ISO Vincristine results in increased expression of RCC1L mRNA CTD PMID:23649840 NCBI chr12:22,543,125...22,574,042
Ensembl chr12:22,543,734...22,574,036 		JBrowse link
G Recql4 RecQ like helicase 4 decreases expression ISO Vincristine results in decreased expression of RECQL4 mRNA CTD PMID:23649840 NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit increases expression ISO Vincristine results in increased expression of REL mRNA CTD PMID:23649840 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
increases phosphorylation		 EXP
ISO		 coenzyme Q10 inhibits the reaction [Vincristine results in increased expression of RELA protein]; Sumatriptan inhibits the reaction [Vincristine results in increased phosphorylation of RELA protein]
KN 93 inhibits the reaction [Vincristine results in increased phosphorylation of RELA protein]		 CTD PMID:29958920 PMID:34286406 PMID:34939713 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Reps1 RALBP1 associated Eps domain containing 1 increases expression ISO Vincristine results in increased expression of REPS1 mRNA CTD PMID:23649840 NCBI chr 1:12,697,742...12,775,562
Ensembl chr 1:12,697,747...12,775,561 		JBrowse link
G Rev1 REV1, DNA directed polymerase decreases expression ISO Vincristine results in decreased expression of REV1 mRNA CTD PMID:23649840 NCBI chr 9:40,278,100...40,351,764
Ensembl chr 9:40,278,101...40,351,576 		JBrowse link
G Rffl ring finger and FYVE-like domain containing E3 ubiquitin protein ligase increases expression ISO Vincristine results in increased expression of RFFL mRNA CTD PMID:23649840 NCBI chr10:67,740,711...67,803,669
Ensembl chr10:67,740,712...67,824,434 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 increases expression ISO Vincristine results in increased expression of RFTN1 mRNA CTD PMID:23649840 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Rgs1 regulator of G-protein signaling 1 increases expression ISO Vincristine results in increased expression of RGS1 mRNA CTD PMID:23649840 NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 increases response to substance ISO RGS10 protein results in increased susceptibility to Vincristine CTD PMID:21044322 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 increases expression ISO Vincristine results in increased expression of RGS16 mRNA CTD PMID:23649840 NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857 		JBrowse link
G Rgs17 regulator of G-protein signaling 17 increases response to substance ISO RGS17 protein results in increased susceptibility to Vincristine CTD PMID:21044322 NCBI chr 1:42,222,248...42,324,625
Ensembl chr 1:42,227,070...42,324,609 		JBrowse link
G Rhof ras homolog family member F, filopodia associated increases expression ISO Vincristine results in increased expression of RHOF mRNA CTD PMID:23649840 NCBI chr12:33,422,375...33,446,689
Ensembl chr12:33,431,280...33,446,703 		JBrowse link
G Rhoq ras homolog family member Q increases expression ISO Vincristine results in increased expression of RHOQ mRNA CTD PMID:23649840 NCBI chr 6:7,613,632...7,652,047 JBrowse link
G Rif1 replication timing regulatory factor 1 decreases expression ISO Vincristine results in decreased expression of RIF1 mRNA CTD PMID:23649840 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 increases expression ISO Vincristine results in increased expression of RIPK2 mRNA CTD PMID:23649840 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Rnase6 ribonuclease A family member 6 decreases expression ISO Vincristine results in decreased expression of RNASE6 mRNA CTD PMID:23649840 NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328 		JBrowse link
G Rnf144a ring finger protein 144A decreases expression ISO Vincristine results in decreased expression of RNF144A mRNA CTD PMID:23649840 NCBI chr 6:42,899,767...43,019,769
Ensembl chr 6:42,903,174...43,020,012 		JBrowse link
G Rnf19b ring finger protein 19B increases expression ISO Vincristine results in increased expression of RNF19B mRNA CTD PMID:23649840 NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380 		JBrowse link
G Rnf213 ring finger protein 213 decreases expression ISO Vincristine results in decreased expression of RNF213 mRNA CTD PMID:23649840 NCBI chr10:104,656,329...104,755,669
Ensembl chr10:104,656,883...104,757,918 		JBrowse link
G Rnf34 ring finger protein 34 increases expression ISO Vincristine results in increased expression of RNF34 mRNA CTD PMID:23649840 NCBI chr12:33,703,655...33,724,606
Ensembl chr12:33,703,673...33,724,586 		JBrowse link
G Rora RAR-related orphan receptor A increases expression ISO Vincristine results in increased expression of RORA mRNA CTD PMID:23649840 NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931 		JBrowse link
G Rpain RPA interacting protein decreases expression ISO Vincristine results in decreased expression of RPAIN mRNA CTD PMID:23649840 NCBI chr10:55,692,410...55,699,910
Ensembl chr10:55,692,417...55,699,933 		JBrowse link
G Rpl10 ribosomal protein L10 decreases expression ISO Vincristine results in decreased expression of RPL10 mRNA CTD PMID:23649840 NCBI chr  X:152,054,562...152,056,769
Ensembl chr  X:152,054,452...152,056,761 		JBrowse link
G Rpl13 ribosomal protein L13 decreases expression ISO Vincristine results in decreased expression of RPL13 mRNA CTD PMID:23649840 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014 		JBrowse link
G Rpl17 ribosomal protein L17 decreases expression ISO Vincristine results in decreased expression of RPL17 mRNA CTD PMID:23649840 NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253 		JBrowse link
G Rpl31 ribosomal protein L31 decreases expression ISO Vincristine results in decreased expression of RPL31 mRNA CTD PMID:23649840 NCBI chr 9:41,647,397...41,651,441
Ensembl chr 9:41,647,426...41,662,129 		JBrowse link
G Rpl37a ribosomal protein L37A decreases expression ISO Vincristine results in decreased expression of RPL37A mRNA CTD PMID:23649840 NCBI chr 9:74,298,843...74,300,926 JBrowse link
G Rpl5 ribosomal protein L5 decreases expression ISO Vincristine results in decreased expression of RPL5 mRNA CTD PMID:23649840 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290 		JBrowse link
G Rpl6 ribosomal protein L6 decreases response to substance ISO RPL6 protein results in decreased susceptibility to Vincristine CTD PMID:15846068 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921 		JBrowse link
G Rpl7 ribosomal protein L7 decreases expression ISO Vincristine results in decreased expression of RPL7 mRNA CTD PMID:23649840 NCBI chr 5:3,217,184...3,220,192 JBrowse link
G Rprd1a regulation of nuclear pre-mRNA domain containing 1A decreases expression ISO Vincristine results in decreased expression of RPRD1A mRNA CTD PMID:23649840 NCBI chr18:15,791,418...15,839,338
Ensembl chr18:15,791,418...15,839,338 		JBrowse link
G Rps24 ribosomal protein S24 decreases expression ISO Vincristine results in decreased expression of RPS24 mRNA CTD PMID:23649840 NCBI chr16:89,538...94,267
Ensembl chr16:89,604...94,279 		JBrowse link
G Rps27l ribosomal protein S27-like increases expression ISO Vincristine results in increased expression of RPS27L mRNA CTD PMID:23649840 NCBI chr 8:67,562,483...67,567,418
Ensembl chr 8:67,562,483...67,567,418 		JBrowse link
G Rragc Ras-related GTP binding C increases expression ISO Vincristine results in increased expression of RRAGC mRNA CTD PMID:23649840 NCBI chr 5:136,148,239...136,167,773
Ensembl chr 5:136,148,276...136,167,767 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression ISO Vincristine results in decreased expression of RRM2 mRNA CTD PMID:23649840 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rrp7a ribosomal RNA processing 7 homolog A decreases expression ISO Vincristine results in decreased expression of RRP7A mRNA CTD PMID:23649840 NCBI chr 7:114,262,929...114,272,817
Ensembl chr 7:114,256,472...114,272,817 		JBrowse link
G Rskr ribosomal protein S6 kinase related decreases expression ISO Vincristine results in decreased expression of RSKR mRNA CTD PMID:23649840 NCBI chr10:63,185,286...63,191,963
Ensembl chr10:63,156,044...63,191,141 		JBrowse link
G Rsrp1 arginine and serine rich protein 1 decreases expression ISO Vincristine results in decreased expression of RSRP1 mRNA CTD PMID:23649840 NCBI chr 5:147,147,774...147,151,523
Ensembl chr 5:147,147,784...147,151,523 		JBrowse link
G Runx3 RUNX family transcription factor 3 increases response to substance ISO RUNX3 protein results in increased susceptibility to Vincristine CTD PMID:15756676 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression ISO Vincristine results in increased expression of S100A4 mRNA CTD PMID:23649840 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO
EXP		 Vincristine results in increased expression of S100A8 mRNA CTD PMID:20624997 PMID:21971985 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression EXP Vincristine results in increased expression of S100A9 mRNA CTD PMID:20624997 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 decreases expression ISO Vincristine results in decreased expression of SAMHD1 mRNA CTD PMID:23649840 NCBI chr 3:145,761,549...145,794,420
Ensembl chr 3:145,761,558...145,794,386 		JBrowse link
G Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 increases expression ISO Vincristine results in increased expression of SAMSN1 mRNA CTD PMID:23649840 NCBI chr11:14,484,523...14,534,900
Ensembl chr11:14,483,893...14,534,900 		JBrowse link
G Sarm1 sterile alpha and TIR motif containing 1 increases expression
multiple interactions		 EXP Vincristine results in increased expression of SARM1 mRNA
coenzyme Q10 inhibits the reaction [Vincristine results in increased expression of SARM1 mRNA]		 CTD PMID:34939713 NCBI chr10:63,369,456...63,393,016
Ensembl chr10:63,369,456...63,392,822 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 increases expression ISO Vincristine results in increased expression of SASH3 mRNA CTD PMID:23649840 NCBI chr  X:127,326,815...127,341,521
Ensembl chr  X:127,326,859...127,341,519 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO Vincristine results in increased expression of SAT1 mRNA CTD PMID:23649840 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813 		JBrowse link
G Sbf2 SET binding factor 2 increases expression ISO Vincristine results in increased expression of SBF2 mRNA CTD PMID:23649840 NCBI chr 1:164,352,892...164,719,883
Ensembl chr 1:164,353,444...164,719,807 		JBrowse link
G Sbno1 strawberry notch homolog 1 increases expression ISO Vincristine results in increased expression of SBNO1 mRNA CTD PMID:23649840 NCBI chr12:32,175,176...32,234,200
Ensembl chr12:32,185,485...32,230,158 		JBrowse link
G Scaf11 SR-related CTD-associated factor 11 increases expression ISO Vincristine results in increased expression of SCAF11 mRNA CTD PMID:23649840 NCBI chr 7:127,571,678...127,624,089
Ensembl chr 7:127,574,463...127,624,101 		JBrowse link
G Scamp2 secretory carrier membrane protein 2 decreases expression ISO Vincristine results in decreased expression of SCAMP2 mRNA CTD PMID:23649840 NCBI chr 8:57,965,612...57,992,248
Ensembl chr 8:57,965,631...57,992,646 		JBrowse link
G Sclt1 sodium channel and clathrin linker 1 increases expression ISO Vincristine results in increased expression of SCLT1 mRNA CTD PMID:23649840 NCBI chr 2:124,605,445...124,763,964
Ensembl chr 2:124,605,658...124,764,065 		JBrowse link
G Scly selenocysteine lyase decreases expression ISO Vincristine results in decreased expression of SCLY mRNA CTD PMID:23649840 NCBI chr 9:91,890,269...91,910,947
Ensembl chr 9:91,890,306...91,910,941 		JBrowse link
G Sdcbp syndecan binding protein increases expression ISO Vincristine results in increased expression of SDCBP mRNA CTD PMID:23649840 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572 		JBrowse link
G Sec31b SEC31 homolog B, COPII coat complex component decreases expression ISO Vincristine results in decreased expression of SEC31B mRNA CTD PMID:23649840 NCBI chr 1:243,376,283...243,404,557
Ensembl chr 1:243,378,456...243,404,557 		JBrowse link
G Sec62 SEC62 homolog, preprotein translocation factor decreases expression ISO Vincristine results in decreased expression of SEC62 mRNA CTD PMID:23649840 NCBI chr 2:112,570,810...112,598,198
Ensembl chr 2:112,570,819...112,601,814 		JBrowse link
G Sele selectin E increases expression EXP Vincristine results in increased expression of SELE mRNA CTD PMID:20624997 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Selenoh selenoprotein H decreases expression ISO Vincristine results in decreased expression of SELENOH mRNA CTD PMID:23649840 NCBI chr 3:69,751,850...69,753,417
Ensembl chr 3:69,752,757...69,753,417 		JBrowse link
G Senp1 SUMO specific peptidase 1 decreases expression ISO Vincristine results in decreased expression of SENP1 mRNA CTD PMID:23649840 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598 		JBrowse link
G Septin6 septin 6 decreases expression ISO Vincristine results in decreased expression of SEPTIN6 mRNA CTD PMID:23649840 NCBI chr  X:116,153,255...116,230,334
Ensembl chr  X:116,153,255...116,230,115 		JBrowse link
G Serinc5 serine incorporator 5 increases expression ISO Vincristine results in increased expression of SERINC5 mRNA CTD PMID:23649840 NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346 		JBrowse link
G Serpinb10 serpin family B member 10 increases expression ISO Vincristine results in increased expression of SERPINB10 mRNA CTD PMID:23649840 NCBI chr13:23,553,348...23,571,182
Ensembl chr13:23,553,430...23,571,182 		JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Vincristine results in increased expression of SERPINB2 mRNA CTD PMID:23649840 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Serpinb8 serpin family B member 8 increases expression ISO Vincristine results in increased expression of SERPINB8 mRNA CTD PMID:23649840 NCBI chr13:23,626,936...23,650,277
Ensembl chr13:23,626,945...23,650,835 		JBrowse link
G Serpine1 serpin family E member 1 increases expression
increases response to substance		 EXP
ISO		 Vincristine results in increased expression of SERPINE1 mRNA
SERPINE1 gene SNP results in increased susceptibility to Vincristine		 CTD PMID:20624997 PMID:21245421 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sertad3 SERTA domain containing 3 decreases expression ISO Vincristine results in decreased expression of SERTAD3 mRNA CTD PMID:23649840 NCBI chr 1:82,763,535...82,767,271
Ensembl chr 1:82,763,149...82,769,001 		JBrowse link
G Sesn1 sestrin 1 increases expression EXP Vincristine results in increased expression of SESN1 mRNA CTD PMID:20624997 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sesn2 sestrin 2 increases expression ISO Vincristine results in increased expression of SESN2 mRNA CTD PMID:23649840 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Setbp1 SET binding protein 1 decreases expression ISO Vincristine results in decreased expression of SETBP1 mRNA CTD PMID:23649840 NCBI chr18:72,190,542...72,551,272
Ensembl chr18:72,191,035...72,552,556 		JBrowse link
G Setd1b SET domain containing 1B, histone lysine methyltransferase decreases expression ISO Vincristine results in decreased expression of SETD1B mRNA CTD PMID:23649840 NCBI chr12:33,395,963...33,421,671
Ensembl chr12:33,396,120...33,426,934 		JBrowse link
G Setd6 SET domain containing 6, protein lysine methyltransferase decreases expression ISO Vincristine results in decreased expression of SETD6 mRNA CTD PMID:23649840 NCBI chr19:9,343,309...9,350,477
Ensembl chr19:9,347,458...9,350,453 		JBrowse link
G Sfxn3 sideroflexin 3 increases expression ISO Vincristine results in increased expression of SFXN3 mRNA CTD PMID:23649840 NCBI chr 1:243,907,958...243,917,065
Ensembl chr 1:243,907,751...243,917,073 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO Vincristine results in increased expression of SGK1 mRNA CTD PMID:23649840 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sh3yl1 SH3 and SYLF domain containing 1 increases expression ISO Vincristine results in increased expression of SH3YL1 mRNA CTD PMID:23649840 NCBI chr 6:47,522,098...47,565,858
Ensembl chr 6:47,522,091...47,565,858 		JBrowse link
G Shisa8 shisa family member 8 decreases expression ISO Vincristine results in decreased expression of SHISA8 mRNA CTD PMID:23649840 NCBI chr 7:113,722,408...113,727,858
Ensembl chr 7:113,722,408...113,727,858 		JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 decreases expression ISO Vincristine results in decreased expression of SIAH1 mRNA CTD PMID:23649840 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808 		JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 increases expression ISO Vincristine results in increased expression of SIAH2 mRNA CTD PMID:23649840 NCBI chr 2:142,913,924...142,931,752
Ensembl chr 2:142,914,003...142,931,950 		JBrowse link
G Sidt2 SID1 transmembrane family, member 2 increases expression ISO Vincristine results in increased expression of SIDT2 mRNA CTD PMID:23649840 NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700 		JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions		 EXP Vincristine results in decreased expression of SIRT1 protein
Quercetin inhibits the reaction [Vincristine results in decreased expression of SIRT1 protein]		 CTD PMID:36808657 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor decreases expression ISO Vincristine results in decreased expression of SIVA1 mRNA CTD PMID:23649840 NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690 		JBrowse link
G Six1 SIX homeobox 1 decreases expression ISO Vincristine results in decreased expression of SIX1 mRNA CTD PMID:23649840 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975 		JBrowse link
G Skil SKI-like proto-oncogene increases expression ISO Vincristine results in increased expression of SKIL mRNA CTD PMID:23649840 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression ISO Vincristine results in decreased expression of SKP2 mRNA CTD PMID:23649840 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338 		JBrowse link
G Slamf1 signaling lymphocytic activation molecule family member 1 increases expression ISO Vincristine results in increased expression of SLAMF1 mRNA CTD PMID:23649840 NCBI chr13:84,270,316...84,305,497
Ensembl chr13:84,270,316...84,305,497 		JBrowse link
G Slamf7 SLAM family member 7 increases expression ISO Vincristine results in increased expression of SLAMF7 mRNA CTD PMID:23649840 NCBI chr13:84,135,656...84,154,528
Ensembl chr13:84,136,899...84,154,105 		JBrowse link
G Slc10a2 solute carrier family 10 member 2 increases response to substance ISO SLC10A2 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475 		JBrowse link
G Slc15a4 solute carrier family 15 member 4 decreases expression ISO Vincristine results in decreased expression of SLC15A4 mRNA CTD PMID:23649840 NCBI chr12:29,048,634...29,082,480
Ensembl chr12:29,063,015...29,082,480 		JBrowse link
G Slc16a14 solute carrier family 16, member 14 decreases expression ISO Vincristine results in decreased expression of SLC16A14 mRNA CTD PMID:23649840 NCBI chr 9:86,110,066...86,137,546
Ensembl chr 9:86,112,894...86,137,318 		JBrowse link
G Slc20a1 solute carrier family 20 member 1 decreases expression ISO Vincristine results in decreased expression of SLC20A1 mRNA CTD PMID:23649840 NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051 		JBrowse link
G Slc22a23 solute carrier family 22, member 23 increases expression ISO Vincristine results in increased expression of SLC22A23 mRNA CTD PMID:23649840 NCBI chr17:30,544,106...30,709,790
Ensembl chr17:30,544,106...30,709,790 		JBrowse link
G Slc25a1 solute carrier family 25 member 1 decreases expression ISO Vincristine results in decreased expression of SLC25A1 mRNA CTD PMID:23649840 NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781 		JBrowse link
G Slc25a11 solute carrier family 25 member 11 decreases expression ISO Vincristine results in decreased expression of SLC25A11 mRNA CTD PMID:23649840 NCBI chr10:55,357,590...55,360,441
Ensembl chr10:55,357,597...55,360,410 		JBrowse link
G Slc25a37 solute carrier family 25 member 37 decreases expression ISO Vincristine results in decreased expression of SLC25A37 mRNA CTD PMID:23649840 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 decreases expression ISO Vincristine results in decreased expression of SLC29A1 mRNA CTD PMID:23649840 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Slc29a2 solute carrier family 29 member 2 decreases expression ISO Vincristine results in decreased expression of SLC29A2 mRNA CTD PMID:23649840 NCBI chr 1:202,327,641...202,335,185
Ensembl chr 1:202,327,354...202,335,171 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases response to substance ISO SLC2A1 protein results in decreased susceptibility to Vincristine CTD PMID:17520257 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc44a5 solute carrier family 44, member 5 increases expression ISO Vincristine results in increased expression of SLC44A5 mRNA CTD PMID:23649840 NCBI chr 2:242,911,050...243,208,018
Ensembl chr 2:242,911,325...243,206,404 		JBrowse link
G Slc4a7 solute carrier family 4 member 7 decreases expression ISO Vincristine results in decreased expression of SLC4A7 mRNA CTD PMID:23649840 NCBI chr15:10,585,307...10,664,780
Ensembl chr15:10,588,979...10,664,781 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Vincristine results in increased expression of SLC7A11 mRNA CTD PMID:23649840 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Slc9a9 solute carrier family 9 member A9 increases expression ISO Vincristine results in increased expression of SLC9A9 mRNA CTD PMID:23649840 NCBI chr 8:95,232,889...95,797,262
Ensembl chr 8:95,232,905...95,796,318 		JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 decreases expression ISO Vincristine results in decreased expression of SLCO4C1 mRNA CTD PMID:23649840 NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715 		JBrowse link
G Smad1 SMAD family member 1 increases expression ISO Vincristine results in increased expression of SMAD1 mRNA CTD PMID:23649840 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad2 SMAD family member 2 decreases expression ISO Vincristine results in decreased expression of SMAD2 mRNA CTD PMID:23649840 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad4 SMAD family member 4 increases expression ISO Vincristine results in increased expression of SMAD4 mRNA CTD PMID:23649840 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smc6 structural maintenance of chromosomes 6 decreases expression ISO Vincristine results in decreased expression of SMC6 mRNA CTD PMID:23649840 NCBI chr 6:33,978,730...34,033,201
Ensembl chr 6:33,978,716...34,031,746 		JBrowse link
G Snapc3 small nuclear RNA activating complex, polypeptide 3 decreases expression ISO Vincristine results in decreased expression of SNAPC3 mRNA CTD PMID:23649840 NCBI chr 5:97,817,827...97,868,494
Ensembl chr 5:97,817,947...97,844,650 		JBrowse link
G Snn stannin increases expression ISO Vincristine results in increased expression of SNN mRNA CTD PMID:23649840 NCBI chr10:4,572,933...4,581,606
Ensembl chr10:4,572,376...4,584,021 		JBrowse link
G Snord104 small nucleolar RNA, C/D box 104 decreases expression ISO Vincristine results in decreased expression of SNORD104 mRNA CTD PMID:23649840 NCBI chr10:91,435,313...91,435,382
Ensembl chr10:91,435,313...91,435,382 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 increases expression ISO Vincristine results in increased expression of SNRNP200 mRNA CTD PMID:23649840 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182 		JBrowse link
G Snrpa1 small nuclear ribonucleoprotein polypeptide A' increases expression ISO Vincristine results in increased expression of SNRPA1 mRNA CTD PMID:23649840 NCBI chr 1:119,641,402...119,654,653
Ensembl chr 1:119,638,481...119,654,653 		JBrowse link
G Snrpn small nuclear ribonucleoprotein polypeptide N decreases expression ISO Vincristine results in decreased expression of SNRPN mRNA CTD PMID:23649840 NCBI chr 1:111,101,327...111,123,400
Ensembl chr 1:111,101,329...111,123,634 		JBrowse link
G Snu13 small nuclear ribonucleoprotein 13 decreases expression ISO Vincristine results in decreased expression of SNU13 mRNA CTD PMID:23649840 NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872
Ensembl chr 1:113,565,295...113,570,872 		JBrowse link
G Snx11 sorting nexin 11 increases expression ISO Vincristine results in increased expression of SNX11 mRNA CTD PMID:23649840 NCBI chr10:81,742,020...81,752,778
Ensembl chr10:81,742,024...81,752,712 		JBrowse link
G Snx25 sorting nexin 25 decreases expression ISO Vincristine results in decreased expression of SNX25 mRNA CTD PMID:23649840 NCBI chr16:46,134,552...46,238,471
Ensembl chr16:46,125,804...46,238,440 		JBrowse link
G Snx4 sorting nexin 4 decreases expression ISO Vincristine results in decreased expression of SNX4 mRNA CTD PMID:23649840 NCBI chr11:67,460,872...67,518,143
Ensembl chr11:67,460,870...67,518,174 		JBrowse link
G Snx5 sorting nexin 5 decreases expression ISO Vincristine results in decreased expression of SNX5 mRNA CTD PMID:23649840 NCBI chr 3:131,621,875...131,641,127
Ensembl chr 3:131,621,880...131,641,192 		JBrowse link
G Sobp sine oculis binding protein homolog decreases expression ISO Vincristine results in decreased expression of SOBP mRNA CTD PMID:23649840 NCBI chr20:46,482,265...46,661,452
Ensembl chr20:46,482,765...46,663,541 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression ISO Vincristine results in increased expression of SOCS3 mRNA CTD PMID:23649840 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression		 ISO bisindolylmaleimide I inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA]; calphostin C inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA]; Cycloheximide promotes the reaction [Vincristine results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA] CTD PMID:9852137 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Son SON DNA and RNA binding protein decreases expression ISO Vincristine results in decreased expression of SON mRNA CTD PMID:23649840 NCBI chr11:30,850,890...30,923,167
Ensembl chr11:30,892,005...30,923,167 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 increases expression ISO Vincristine results in increased expression of SOS1 mRNA CTD PMID:16001973 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Sp1 Sp1 transcription factor decreases expression ISO Vincristine results in decreased expression of SP1 mRNA CTD PMID:23649840 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961 		JBrowse link
G Sp100 SP100 nuclear antigen increases expression ISO Vincristine results in increased expression of SP100 mRNA CTD PMID:23649840 NCBI chr 9:86,310,990...86,377,036
Ensembl chr 9:86,311,032...86,377,034 		JBrowse link
G Sp4 Sp4 transcription factor decreases expression ISO Vincristine results in decreased expression of SP4 mRNA CTD PMID:23649840 NCBI chr 6:139,187,458...139,252,741
Ensembl chr 6:139,192,147...139,252,126 		JBrowse link
G Spart spartin decreases expression ISO Vincristine results in decreased expression of SPART mRNA CTD PMID:23649840 NCBI chr 2:139,292,630...139,319,248
Ensembl chr 2:139,292,355...139,319,248 		JBrowse link
G Spic Spi-C transcription factor increases expression ISO Vincristine results in increased expression of SPIC mRNA CTD PMID:23649840 NCBI chr 7:23,069,815...23,077,517
Ensembl chr 7:23,069,821...23,077,548 		JBrowse link
G Spin4 spindlin family, member 4 decreases expression ISO Vincristine results in decreased expression of SPIN4 mRNA CTD PMID:23649840 NCBI chr  X:59,888,728...59,892,817
Ensembl chr  X:59,891,581...59,892,330 		JBrowse link
G Spon1 spondin 1 increases expression EXP Vincristine results in increased expression of SPON1 mRNA CTD PMID:20624997 NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226 		JBrowse link
G Spred1 sprouty-related, EVH1 domain containing 1 increases expression ISO Vincristine results in increased expression of SPRED1 mRNA CTD PMID:23649840 NCBI chr 3:103,983,120...104,050,321
Ensembl chr 3:103,983,072...104,049,718 		JBrowse link
G Spry1 sprouty RTK signaling antagonist 1 decreases expression ISO Vincristine results in decreased expression of SPRY1 mRNA CTD PMID:23649840 NCBI chr 2:120,557,256...120,561,917
Ensembl chr 2:120,556,706...120,566,189 		JBrowse link
G Sqstm1 sequestosome 1 multiple interactions
increases expression		 ISO [cotylenin A co-treated with Vincristine] results in increased degradation of SQSTM1 protein
Vincristine results in increased expression of SQSTM1 mRNA		 CTD PMID:23649840 PMID:25672400 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO Vincristine results in decreased expression of SREBF1 mRNA CTD PMID:23649840 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srek1 splicing regulatory glutamic acid and lysine rich protein 1 decreases expression ISO Vincristine results in decreased expression of SREK1 mRNA CTD PMID:23649840 NCBI chr 2:34,849,548...34,885,120
Ensembl chr 2:34,852,458...34,884,972 		JBrowse link
G Srgn serglycin increases expression ISO Vincristine results in increased expression of SRGN mRNA CTD PMID:23649840 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406 		JBrowse link
G Sri sorcin decreases response to substance ISO SRI protein results in decreased susceptibility to Vincristine CTD PMID:18423116 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077 		JBrowse link
G Srm spermidine synthase decreases expression ISO Vincristine results in decreased expression of SRM mRNA CTD PMID:23649840 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405 		JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 decreases expression ISO Vincristine results in decreased expression of SRSF3 mRNA CTD PMID:23649840 NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078 		JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 decreases expression ISO Vincristine results in decreased expression of SRSF7 mRNA CTD PMID:23649840 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 decreases expression ISO Vincristine results in decreased expression of SSBP1 mRNA CTD PMID:23649840 NCBI chr 4:69,266,024...69,276,135
Ensembl chr 4:69,266,102...69,276,135 		JBrowse link
G Sstr2 somatostatin receptor 2 increases expression ISO Vincristine results in increased expression of SSTR2 mRNA CTD PMID:23649840 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351 		JBrowse link
G Stag1 STAG1 cohesin complex component increases expression ISO Vincristine results in increased expression of STAG1 mRNA CTD PMID:23649840 NCBI chr 8:101,179,039...101,564,684
Ensembl chr 8:101,179,039...101,564,677 		JBrowse link
G Stambpl1 STAM binding protein-like 1 decreases expression ISO Vincristine results in decreased expression of STAMBPL1 mRNA CTD PMID:23649840 NCBI chr 1:231,699,620...231,745,034
Ensembl chr 1:231,699,995...231,745,032 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Vincristine results in increased expression of STAT1 mRNA CTD PMID:16001973 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases expression		 EXP Quercetin inhibits the reaction [Vincristine results in increased expression of STAT3 protein] CTD PMID:36808657 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Vincristine results in decreased expression of STIP1 mRNA CTD PMID:23649840 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
G Stk4 serine/threonine kinase 4 increases expression ISO Vincristine results in increased expression of STK4 mRNA CTD PMID:23649840 NCBI chr 3:152,745,958...152,827,747
Ensembl chr 3:152,745,681...152,827,744 		JBrowse link
G Strip2 striatin interacting protein 2 decreases expression ISO Vincristine results in decreased expression of STRIP2 mRNA CTD PMID:23649840 NCBI chr 4:58,536,034...58,578,279
Ensembl chr 4:58,536,055...58,578,291 		JBrowse link
G Sts steroid sulfatase decreases expression ISO Vincristine results in decreased expression of STS mRNA CTD PMID:23649840 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Stx12 syntaxin 12 increases expression ISO Vincristine results in increased expression of STX12 mRNA CTD PMID:23649840 NCBI chr 5:145,062,978...145,092,423
Ensembl chr 5:145,063,587...145,092,377 		JBrowse link
G Sun2 Sad1 and UNC84 domain containing 2 increases expression ISO Vincristine results in increased expression of SUN2 mRNA CTD PMID:23649840 NCBI chr 7:111,275,374...111,292,565
Ensembl chr 7:111,275,380...111,292,553 		JBrowse link
G Supt20h SPT20 homolog, SAGA complex component increases expression ISO Vincristine results in increased expression of SUPT20H mRNA CTD PMID:23649840 NCBI chr 2:138,897,316...138,930,493
Ensembl chr 2:138,897,416...138,930,495 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit increases expression ISO Vincristine results in increased expression of SUZ12 mRNA CTD PMID:23649840 NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738 		JBrowse link
G Syf2 SYF2 pre-mRNA-splicing factor increases expression ISO Vincristine results in increased expression of SYF2 mRNA CTD PMID:23649840 NCBI chr 5:147,156,492...147,164,416
Ensembl chr 5:147,156,480...147,164,414 		JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein decreases expression ISO Vincristine results in decreased expression of SYNCRIP mRNA CTD PMID:23649840 NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515 		JBrowse link
G Syne2 spectrin repeat containing nuclear envelope protein 2 decreases expression ISO Vincristine results in decreased expression of SYNE2 mRNA CTD PMID:23649840 NCBI chr 6:94,537,088...94,848,085
Ensembl chr 6:94,537,088...94,848,064 		JBrowse link
G Sypl2 synaptophysin-like 2 increases expression ISO Vincristine results in increased expression of SYPL2 mRNA CTD PMID:23649840 NCBI chr 2:195,849,062...195,863,794
Ensembl chr 2:195,849,062...195,863,794 		JBrowse link
G Sytl3 synaptotagmin-like 3 increases expression ISO Vincristine results in increased expression of SYTL3 mRNA CTD PMID:23649840 NCBI chr 1:46,896,308...46,967,461
Ensembl chr 1:46,911,217...46,967,460 		JBrowse link
G Taf15 TATA-box binding protein associated factor 15 increases expression ISO Vincristine results in increased expression of TAF15 mRNA CTD PMID:23649840 NCBI chr10:68,272,921...68,304,951
Ensembl chr10:68,272,969...68,304,949 		JBrowse link
G Taf1d TATA-box binding protein associated factor, RNA polymerase I subunit D decreases expression ISO Vincristine results in decreased expression of TAF1D mRNA CTD PMID:23649840 NCBI chr 8:12,146,511...12,156,647
Ensembl chr 8:12,146,605...12,156,618 		JBrowse link
G Taf5l1 TATA-box binding protein associated factor 5 like 1 decreases expression ISO Vincristine results in decreased expression of TAF5L mRNA CTD PMID:23649840 NCBI chr19:51,991,704...52,011,001
Ensembl chr19:51,991,708...52,011,295 		JBrowse link
G Tank TRAF family member-associated NFKB activator decreases expression
increases expression		 ISO Vincristine results in decreased expression of TANK mRNA
Vincristine results in increased expression of TANK mRNA		 CTD PMID:23649840 NCBI chr 3:46,114,230...46,190,270
Ensembl chr 3:46,114,274...46,190,264 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression ISO Vincristine results in increased expression of TAP1 mRNA CTD PMID:23649840 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
G Tasor2 transcription activation suppressor family member 2 increases expression ISO Vincristine results in increased expression of TASOR2 mRNA CTD PMID:23649840 NCBI chr17:66,583,554...66,650,127
Ensembl chr17:66,594,908...66,649,135 		JBrowse link
G Tbc1d12 TBC1 domain family, member 12 decreases expression ISO Vincristine results in decreased expression of TBC1D12 mRNA CTD PMID:23649840 NCBI chr 1:236,603,597...236,685,859
Ensembl chr 1:236,603,607...236,685,859 		JBrowse link
G Tbc1d4 TBC1 domain family, member 4 increases expression ISO Vincristine results in increased expression of TBC1D4 mRNA CTD PMID:23649840 NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265 		JBrowse link
G Tbc1d8b TBC1 domain family member 8B decreases expression ISO Vincristine results in decreased expression of TBC1D8B mRNA CTD PMID:23649840 NCBI chr  X:103,319,181...103,407,137
Ensembl chr  X:103,319,340...103,407,133 		JBrowse link
G Tbx22 T-box transcription factor 22 increases expression ISO Vincristine results in increased expression of TBX22 mRNA CTD PMID:23649840 NCBI chr  X:72,723,619...72,774,647
Ensembl chr  X:72,723,617...72,774,647 		JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 decreases expression ISO Vincristine results in decreased expression of TCAF1 mRNA CTD PMID:23649840 NCBI chr 4:71,589,674...71,639,274
Ensembl chr 4:71,591,200...71,613,309 		JBrowse link
G Tcea2 transcription elongation factor A2 increases expression ISO Vincristine results in increased expression of TCEA2 mRNA CTD PMID:23649840 NCBI chr 3:168,796,244...168,804,125
Ensembl chr 3:168,796,331...168,804,116 		JBrowse link
G Tcf19 transcription factor 19 decreases expression ISO Vincristine results in decreased expression of TCF19 mRNA CTD PMID:23649840 NCBI chr20:3,218,756...3,222,861
Ensembl chr20:3,218,693...3,223,271 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 decreases expression ISO Vincristine results in decreased expression of TCIRG1 mRNA CTD PMID:23649840 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742 		JBrowse link
G Tdrd9 tudor domain containing 9 increases expression ISO Vincristine results in increased expression of TDRD9 mRNA CTD PMID:23649840 NCBI chr 6:131,029,644...131,145,076
Ensembl chr 6:131,029,652...131,144,651 		JBrowse link
G Tenm2 teneurin transmembrane protein 2 increases expression ISO Vincristine results in increased expression of TENM2 mRNA CTD PMID:23649840 NCBI chr10:20,480,662...21,706,415
Ensembl chr10:20,481,854...21,705,597 		JBrowse link
G Tent2 terminal nucleotidyltransferase 2 increases expression ISO Vincristine results in increased expression of TENT2 mRNA CTD PMID:23649840 NCBI chr 2:24,380,135...24,432,099
Ensembl chr 2:24,380,225...24,432,099 		JBrowse link
G Tent5c terminal nucleotidyltransferase 5C decreases expression ISO Vincristine results in decreased expression of TENT5C mRNA CTD PMID:23649840 NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744 		JBrowse link
G Tfap2a transcription factor AP-2 alpha decreases expression ISO Vincristine results in decreased expression of TFAP2A mRNA CTD PMID:23649840 NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507 		JBrowse link
G Tfpi tissue factor pathway inhibitor increases expression ISO Vincristine results in increased expression of TFPI mRNA CTD PMID:23649840 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Tgds TDP-glucose 4,6-dehydratase increases expression ISO Vincristine results in increased expression of TGDS mRNA CTD PMID:23649840 NCBI chr15:95,175,064...95,195,555
Ensembl chr15:95,174,608...95,195,554 		JBrowse link
G Tgfbi transforming growth factor, beta induced decreases response to substance ISO TGFBI mRNA results in decreased susceptibility to Vincristine CTD PMID:25199881 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240 		JBrowse link
G Tgfbr3 transforming growth factor beta receptor 3 decreases expression ISO Vincristine results in decreased expression of TGFBR3 mRNA CTD PMID:23649840 NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341 		JBrowse link
G Thada THADA, armadillo repeat containing increases expression ISO Vincristine results in increased expression of THADA mRNA CTD PMID:23649840 NCBI chr 6:10,183,942...10,488,007
Ensembl chr 6:10,183,982...10,487,159 		JBrowse link
G Thbd thrombomodulin decreases response to substance ISO THBD protein results in decreased susceptibility to Vincristine CTD PMID:27474498 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Vincristine results in increased expression of THBS1 mRNA CTD PMID:20624997 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Them6 thioesterase superfamily member 6 decreases expression ISO Vincristine results in decreased expression of THEM6 mRNA CTD PMID:23649840 NCBI chr 7:106,606,570...106,609,747
Ensembl chr 7:106,606,570...106,609,746 		JBrowse link
G Themis2 thymocyte selection associated family member 2 increases expression ISO Vincristine results in increased expression of THEMIS2 mRNA CTD PMID:23649840 NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Vincristine binds to and results in decreased activity of THRA protein CTD PMID:25752796 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase increases expression ISO Vincristine results in increased expression of TIGAR mRNA CTD PMID:23649840 NCBI chr 4:159,927,136...159,946,077
Ensembl chr 4:159,927,139...159,946,029 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression EXP
ISO		 Vincristine results in increased expression of TIMP1 mRNA CTD PMID:20624997 PMID:23649840 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tinag tubulointerstitial nephritis antigen decreases expression ISO Vincristine results in decreased expression of TINAG mRNA CTD PMID:23649840 NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077 		JBrowse link
G Tirap TIR domain containing adaptor protein decreases expression ISO Vincristine results in decreased expression of TIRAP mRNA CTD PMID:23649840 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tlcd1 TLC domain containing 1 decreases expression ISO Vincristine results in decreased expression of TLCD1 mRNA CTD PMID:23649840 NCBI chr10:63,074,469...63,076,502
Ensembl chr10:63,074,469...63,076,501 		JBrowse link
G Tlr10 toll-like receptor 10 decreases expression ISO Vincristine results in decreased expression of TLR10 mRNA CTD PMID:23649840 NCBI chr14:43,400,843...43,414,056
Ensembl chr14:43,406,217...43,413,917 		JBrowse link
G Tm2d1 TM2 domain containing 1 decreases expression ISO Vincristine results in decreased expression of TM2D1 mRNA CTD PMID:23649840 NCBI chr 5:113,020,793...113,062,134
Ensembl chr 5:113,020,760...113,050,933 		JBrowse link
G Tmcc3 transmembrane and coiled-coil domain family 3 increases expression ISO Vincristine results in increased expression of TMCC3 mRNA CTD PMID:23649840 NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926 		JBrowse link
G Tmco6 transmembrane and coiled-coil domains 6 decreases expression ISO Vincristine results in decreased expression of TMCO6 mRNA CTD PMID:23649840 NCBI chr18:28,349,248...28,355,843
Ensembl chr18:28,349,248...28,355,843 		JBrowse link
G Tmem106c transmembrane protein 106C decreases expression ISO Vincristine results in decreased expression of TMEM106C mRNA CTD PMID:23649840 NCBI chr 7:129,088,468...129,094,128
Ensembl chr 7:129,088,498...129,094,130 		JBrowse link
G Tmem107 transmembrane protein 107 decreases expression ISO Vincristine results in decreased expression of TMEM107 mRNA CTD PMID:23649840 NCBI chr10:53,772,153...53,774,685
Ensembl chr10:53,771,784...53,774,676 		JBrowse link
G Tmem163 transmembrane protein 163 increases expression ISO Vincristine results in increased expression of TMEM163 mRNA CTD PMID:23649840 NCBI chr13:38,967,913...39,141,664
Ensembl chr13:38,968,101...39,141,452 		JBrowse link
G Tmem177 transmembrane protein 177 decreases expression ISO Vincristine results in decreased expression of TMEM177 mRNA CTD PMID:23649840 NCBI chr13:31,023,893...31,027,368
Ensembl chr13:31,023,455...31,027,378 		JBrowse link
G Tmem200a transmembrane protein 200A decreases expression ISO Vincristine results in decreased expression of TMEM200A mRNA CTD PMID:23649840 NCBI chr 1:19,323,646...19,408,324
Ensembl chr 1:19,323,829...19,406,453 		JBrowse link
G Tmem223 transmembrane protein 223 decreases expression ISO Vincristine results in decreased expression of TMEM223 mRNA CTD PMID:23649840 NCBI chr 1:205,668,716...205,670,077
Ensembl chr 1:205,662,063...205,670,056 		JBrowse link
G Tmem267 transmembrane protein 267 increases expression ISO Vincristine results in increased expression of TMEM267 mRNA CTD PMID:23649840 NCBI chr 2:51,580,210...51,588,937
Ensembl chr 2:51,581,252...51,587,636 		JBrowse link
G Tmem38a transmembrane protein 38a decreases expression ISO Vincristine results in decreased expression of TMEM38A mRNA CTD PMID:23649840 NCBI chr16:17,258,160...17,274,204
Ensembl chr16:17,258,164...17,273,415 		JBrowse link
G Tmem43 transmembrane protein 43 increases expression ISO Vincristine results in increased expression of TMEM43 mRNA CTD PMID:23649840 NCBI chr 4:123,977,680...123,992,823
Ensembl chr 4:123,977,625...123,992,825 		JBrowse link
G Tmem80 transmembrane protein 80 decreases expression ISO Vincristine results in decreased expression of TMEM80 mRNA CTD PMID:23649840 NCBI chr 1:196,435,999...196,444,368
Ensembl chr 1:196,436,003...196,444,367
Ensembl chr 1:196,436,003...196,444,367 		JBrowse link
G Tmf1 TATA element modulatory factor 1 increases expression ISO Vincristine results in increased expression of TMF1 mRNA CTD PMID:23649840 NCBI chr 4:129,759,952...129,785,705
Ensembl chr 4:129,763,114...129,785,629 		JBrowse link
G Tmx4 thioredoxin-related transmembrane protein 4 decreases expression ISO Vincristine results in decreased expression of TMX4 mRNA CTD PMID:23649840 NCBI chr 3:121,856,237...121,899,680
Ensembl chr 3:121,856,261...121,899,641 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP
ISO		 coenzyme Q10 inhibits the reaction [Vincristine results in increased expression of TNF protein]; Pregabalin inhibits the reaction [Vincristine results in increased expression of TNF protein]; Sumatriptan inhibits the reaction [Vincristine results in increased expression of TNF mRNA]; tetrahydrocurcumin inhibits the reaction [Vincristine results in increased expression of TNF protein]; Tropisetron inhibits the reaction [Vincristine results in increased expression of TNF protein]
KN 93 inhibits the reaction [Vincristine results in increased expression of TNF mRNA]
Vincristine results in increased expression of TNF mRNA; Vincristine results in increased expression of TNF protein		 CTD PMID:23649840 PMID:24374478 PMID:26102012 PMID:29958920 PMID:34286406 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Vincristine results in increased expression of TNFAIP3 mRNA CTD PMID:23649840 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Vincristine results in increased expression of TNFAIP6 mRNA CTD PMID:23649840 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tnfaip8l1 TNF alpha induced protein 8 like 1 increases expression ISO Vincristine results in increased expression of TNFAIP8L1 mRNA CTD PMID:23649840 NCBI chr 9:988,587...999,342
Ensembl chr 9:988,594...1,002,254 		JBrowse link
G Tnfrsf17 TNF receptor superfamily member 17 decreases expression ISO Vincristine results in decreased expression of TNFRSF17 mRNA CTD PMID:23649840 NCBI chr10:4,301,023...4,306,889
Ensembl chr10:4,301,038...4,306,788 		JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 decreases expression ISO Vincristine results in decreased expression of TNFRSF19 mRNA CTD PMID:23649840 NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Vincristine results in increased expression of TNFRSF9 mRNA CTD PMID:23649840 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000 		JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO Vincristine results in increased expression of TNFSF10 mRNA CTD PMID:23649840 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnfsf4 TNF superfamily member 4 increases expression ISO Vincristine results in increased expression of TNFSF4 mRNA CTD PMID:23649840 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Vincristine results in increased expression of TNFSF9 mRNA CTD PMID:23649840 NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 increases expression ISO Vincristine results in increased expression of TNIP2 mRNA CTD PMID:23649840 NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265 		JBrowse link
G Tnni3 troponin I3, cardiac type increases expression EXP Vincristine results in increased expression of TNNI3 protein CTD PMID:20624997 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580 		JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP Vincristine inhibits the reaction [Isoproterenol results in increased secretion of TNNT2 protein] CTD PMID:25537132 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 decreases expression ISO Vincristine results in decreased expression of TOMM70 mRNA CTD PMID:23649840 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO Vincristine results in decreased expression of TOP2A mRNA CTD PMID:23649840 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Topbp1 DNA topoisomerase II binding protein 1 decreases expression ISO Vincristine results in decreased expression of TOPBP1 mRNA CTD PMID:23649840 NCBI chr 8:103,887,805...103,931,662
Ensembl chr 8:103,887,865...103,931,674 		JBrowse link
G Tp53 tumor protein p53 increases response to substance
increases glutathionylation
increases expression
multiple interactions
increases activity		 ISO TP53 protein results in increased susceptibility to Vincristine
Vincristine results in increased glutathionylation of TP53 protein
Vincristine results in increased expression of TP53 protein
[Doxorubicin co-treated with Vincristine co-treated with Etoposide co-treated with Mitotane] results in decreased expression of TP53 protein
Vincristine results in increased activity of TP53 protein		 CTD PMID:9815696 PMID:12082016 PMID:14704126 PMID:15131059 PMID:17555331 More... NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Vincristine results in increased expression of TP53I3 mRNA CTD PMID:23649840 NCBI chr 6:27,818,327...27,825,753 JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Vincristine results in increased expression of TP53INP1 mRNA CTD PMID:23649840 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968 		JBrowse link
G Tpcn2 two pore segment channel 2 increases expression ISO Vincristine results in increased expression of TPCN2 mRNA CTD PMID:23649840 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236 		JBrowse link
G Tpd52 tumor protein D52 decreases expression ISO Vincristine results in decreased expression of TPD52 mRNA CTD PMID:23649840 NCBI chr 2:92,735,365...92,816,079
Ensembl chr 2:92,735,620...92,816,622 		JBrowse link
G Tpd52l1 TPD52 like 1 increases expression EXP Vincristine results in increased expression of TPD52L1 mRNA CTD PMID:20624997 NCBI chr 1:26,172,038...26,290,704
Ensembl chr 1:26,172,170...26,291,109 		JBrowse link
G Tpi1 triosephosphate isomerase 1 affects response to substance ISO TPI1 protein affects the susceptibility to Vincristine CTD PMID:18309519 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Tpm4 tropomyosin 4 increases expression ISO Vincristine results in increased expression of TPM4 mRNA CTD PMID:23649840 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984 		JBrowse link
G Tprg1l tumor protein p63 regulated 1-like increases expression ISO Vincristine results in increased expression of TPRG1L mRNA CTD PMID:23649840 NCBI chr 5:164,722,151...164,725,358
Ensembl chr 5:164,710,285...164,725,425 		JBrowse link
G Tra2a transformer 2 alpha increases expression ISO Vincristine results in increased expression of TRA2A mRNA CTD PMID:23649840 NCBI chr 4:78,220,838...78,239,737
Ensembl chr 4:78,220,883...78,239,712 		JBrowse link
G Traf1 TNF receptor-associated factor 1 increases expression ISO Vincristine results in increased expression of TRAF1 mRNA CTD PMID:23649840 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
G Traf3ip3 TRAF3 interacting protein 3 decreases expression ISO Vincristine results in decreased expression of TRAF3IP3 mRNA CTD PMID:23649840 NCBI chr13:104,694,802...104,719,655
Ensembl chr13:104,694,805...104,719,673 		JBrowse link
G Trappc10 trafficking protein particle complex subunit 10 increases expression ISO Vincristine results in increased expression of TRAPPC10 mRNA CTD PMID:23649840 NCBI chr20:10,438,737...10,499,074
Ensembl chr20:10,438,737...10,499,074 		JBrowse link
G Trex1 three prime repair exonuclease 1 decreases expression ISO Vincristine results in decreased expression of TREX1 mRNA CTD PMID:23649840 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796 		JBrowse link
G Trib1 tribbles pseudokinase 1 decreases expression ISO Vincristine results in decreased expression of TRIB1 mRNA CTD PMID:23649840 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731 		JBrowse link
G Trim13 tripartite motif-containing 13 decreases expression ISO Vincristine results in decreased expression of TRIM13 mRNA CTD PMID:23649840 NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677 		JBrowse link
G Trim29 tripartite motif-containing 29 increases expression ISO Vincristine results in increased expression of TRIM29 mRNA CTD PMID:23649840 NCBI chr 8:43,682,221...43,706,992
Ensembl chr 8:43,682,221...43,706,992 		JBrowse link
G Trim45 tripartite motif-containing 45 decreases expression ISO Vincristine results in decreased expression of TRIM45 mRNA CTD PMID:23649840 NCBI chr 2:188,349,979...188,359,205
Ensembl chr 2:188,349,744...188,359,204 		JBrowse link
G Trio trio Rho guanine nucleotide exchange factor increases expression ISO Vincristine results in increased expression of TRIO mRNA CTD PMID:23649840 NCBI chr 2:78,505,069...78,801,384
Ensembl chr 2:78,505,070...78,803,135 		JBrowse link
G Trir telomerase RNA component interacting RNase decreases expression ISO Vincristine results in decreased expression of TRIR mRNA CTD PMID:23649840 NCBI chr19:23,125,083...23,128,502
Ensembl chr19:23,125,083...23,128,510 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 decreases expression ISO Vincristine results in decreased expression of TRPV1 protein CTD PMID:38458354 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 increases expression ISO Vincristine results in increased expression of TRPV2 mRNA CTD PMID:23649840 NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260 		JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases response to substance EXP TRPV4 protein results in increased susceptibility to Vincristine CTD PMID:18234883 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
G Tsc22d1 TSC22 domain family, member 1 decreases expression ISO Vincristine results in decreased expression of TSC22D1 mRNA CTD PMID:23649840 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958 		JBrowse link
G Tsen15 tRNA splicing endonuclease subunit 15 decreases expression ISO Vincristine results in decreased expression of TSEN15 mRNA CTD PMID:23649840 NCBI chr13:64,490,216...64,505,591
Ensembl chr13:64,490,218...64,505,617 		JBrowse link
G Tsg101 tumor susceptibility 101 affects response to substance ISO TSG101 affects the susceptibility to Vincristine CTD PMID:15044860 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554 		JBrowse link
G Tshz1 teashirt zinc finger homeobox 1 decreases expression ISO Vincristine results in decreased expression of TSHZ1 mRNA CTD PMID:23649840 NCBI chr18:77,376,399...77,452,815
Ensembl chr18:77,377,394...77,453,509 		JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 decreases expression ISO Vincristine results in decreased expression of TTC3 mRNA CTD PMID:23649840 NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975 		JBrowse link
G Ttc9c tetratricopeptide repeat domain 9C increases expression
decreases expression		 ISO Vincristine results in increased expression of TTC9C mRNA
Vincristine results in decreased expression of TTC9C mRNA		 CTD PMID:23649840 NCBI chr 1:205,701,768...205,712,782
Ensembl chr 1:205,701,768...205,712,773 		JBrowse link
G Ttyh2 tweety family member 2 increases expression ISO Vincristine results in increased expression of TTYH2 mRNA CTD PMID:23649840 NCBI chr10:99,709,063...99,753,449
Ensembl chr10:99,709,007...99,753,444 		JBrowse link
G Tuba1b tubulin, alpha 1B decreases expression ISO
EXP		 Vincristine results in decreased expression of TUBA1B mRNA CTD PMID:20624997 PMID:23649840 NCBI chr 7:130,090,663...130,093,644
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression ISO Vincristine results in decreased expression of TUBA1C mRNA CTD PMID:23649840 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647 		JBrowse link
G Tuba3b tubulin, alpha 3B decreases expression ISO Vincristine results in decreased expression of TUBA3D mRNA CTD PMID:23649840 NCBI chr 4:178,588,779...178,594,328
Ensembl chr 4:178,588,779...178,594,326 		JBrowse link
G Tuba4a tubulin, alpha 4A decreases expression EXP
ISO		 Vincristine results in decreased expression of TUBA4A mRNA CTD PMID:20624997 PMID:23649840 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918 		JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression ISO Vincristine results in decreased expression of TUBB3 mRNA CTD PMID:23649840 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression ISO
EXP		 Vincristine results in decreased expression of TUBB4B mRNA CTD PMID:20624997 PMID:23649840 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296 		JBrowse link
G Tubb5 tubulin, beta 5 class I decreases expression ISO
EXP		 Vincristine results in decreased expression of TUBB mRNA
Vincristine results in decreased expression of TUBB5 mRNA		 CTD PMID:20624997 PMID:23649840 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Tubg1 tubulin, gamma 1 decreases expression ISO
EXP		 Vincristine results in decreased expression of TUBG1 mRNA CTD PMID:20624997 PMID:23649840 NCBI chr10:86,052,845...86,059,436
Ensembl chr10:86,052,743...86,059,433 		JBrowse link
G Tubgcp5 tubulin gamma complex component 5 decreases expression ISO Vincristine results in decreased expression of TUBGCP5 mRNA CTD PMID:23649840 NCBI chr 1:106,636,526...106,672,175
Ensembl chr 1:106,636,526...106,672,175 		JBrowse link
G Tulp4 TUB like protein 4 increases expression ISO Vincristine results in increased expression of TULP4 mRNA CTD PMID:23649840 NCBI chr 1:46,682,416...46,813,167
Ensembl chr 1:46,682,863...46,809,688 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 affects response to substance ISO TWF1 protein affects the susceptibility to Vincristine CTD PMID:19783987 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
G Txnip thioredoxin interacting protein increases expression ISO Vincristine results in increased expression of TXNIP mRNA CTD PMID:23649840 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO TYMP inhibits the reaction [Vincristine results in increased phosphorylation of BCL2 protein] CTD PMID:15907805 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874 		JBrowse link
G Tyms thymidylate synthetase affects response to substance ISO TYMS gene polymorphism affects the susceptibility to Vincristine CTD PMID:15713801 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G U2surp U2 snRNP-associated SURP domain containing increases expression ISO Vincristine results in increased expression of U2SURP mRNA CTD PMID:23649840 NCBI chr 8:96,018,932...96,075,795
Ensembl chr 8:96,022,957...96,075,691 		JBrowse link
G Ubald2 UBA-like domain containing 2 increases expression ISO Vincristine results in increased expression of UBALD2 mRNA CTD PMID:23649840 NCBI chr10:101,662,507...101,667,089
Ensembl chr10:101,658,127...101,667,061 		JBrowse link
G Ubap2 ubiquitin-associated protein 2 decreases expression ISO Vincristine results in decreased expression of UBAP2 mRNA CTD PMID:23649840 NCBI chr 5:56,348,243...56,437,403
Ensembl chr 5:56,348,246...56,437,049 		JBrowse link
G Ubc ubiquitin C decreases expression ISO Vincristine results in decreased expression of UBC mRNA CTD PMID:23649840 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression ISO Vincristine results in decreased expression of UBE2C mRNA CTD PMID:23649840 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339 		JBrowse link
G Ube2g1 ubiquitin-conjugating enzyme E2G 1 decreases expression ISO Vincristine results in decreased expression of UBE2G1 mRNA CTD PMID:23649840 NCBI chr10:57,225,963...57,306,748
Ensembl chr10:57,225,952...57,308,568 		JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I decreases expression ISO Vincristine results in decreased expression of UBE2I mRNA CTD PMID:23649840 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443 		JBrowse link
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 decreases expression ISO Vincristine results in decreased expression of UBE2J1 mRNA CTD PMID:23649840 NCBI chr 5:47,422,476...47,441,476
Ensembl chr 5:47,422,587...47,441,461 		JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 increases expression ISO Vincristine results in increased expression of UBR2 mRNA CTD PMID:23649840 NCBI chr 9:13,982,427...14,062,315
Ensembl chr 9:13,982,329...14,062,139 		JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 increases expression ISO Vincristine results in increased expression of UBR4 mRNA CTD PMID:23649840 NCBI chr 5:151,635,825...151,743,931
Ensembl chr 5:151,635,868...151,743,784 		JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 increases expression EXP Vincristine results in increased expression of UCHL1 protein CTD PMID:16797537 NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Ucp2 uncoupling protein 2 decreases expression ISO Vincristine results in decreased expression of UCP2 mRNA CTD PMID:23649840 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase increases expression ISO Vincristine results in increased expression of UGCG mRNA CTD PMID:23649840 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393 		JBrowse link
G Uggt2 UDP-glucose glycoprotein glucosyltransferase 2 increases expression ISO Vincristine results in increased expression of UGGT2 mRNA CTD PMID:23649840 NCBI chr15:96,074,557...96,239,365
Ensembl chr15:96,074,564...96,237,806 		JBrowse link
G Unc119 unc-119 lipid binding chaperone increases expression ISO Vincristine results in increased expression of UNC119 mRNA CTD PMID:23649840 NCBI chr10:63,237,862...63,243,339
Ensembl chr10:63,237,903...63,243,339 		JBrowse link
G Upb1 beta-ureidopropionase 1 increases expression ISO Vincristine results in increased expression of UPB1 mRNA CTD PMID:23649840 NCBI chr20:13,217,252...13,243,590
Ensembl chr20:13,217,258...13,243,590 		JBrowse link
G Urod uroporphyrinogen decarboxylase decreases expression ISO Vincristine results in decreased expression of UROD mRNA CTD PMID:23649840 NCBI chr 5:130,464,695...130,468,783
Ensembl chr 5:130,455,217...130,468,808 		JBrowse link
G Usp12 ubiquitin specific peptidase 12 increases expression ISO Vincristine results in increased expression of USP12 mRNA CTD PMID:23649840 NCBI chr12:8,309,845...8,363,686
Ensembl chr12:8,309,750...8,363,656 		JBrowse link
G Usp25 ubiquitin specific peptidase 25 decreases expression ISO Vincristine results in decreased expression of USP25 mRNA CTD PMID:23649840 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348 		JBrowse link
G Usp34 ubiquitin specific peptidase 34 increases expression ISO Vincristine results in increased expression of USP34 mRNA CTD PMID:23649840 NCBI chr14:97,285,799...97,476,376
Ensembl chr14:97,286,018...97,476,376 		JBrowse link
G Usp37 ubiquitin specific peptidase 37 decreases expression ISO Vincristine results in decreased expression of USP37 mRNA CTD PMID:23649840 NCBI chr 9:76,018,863...76,118,732
Ensembl chr 9:76,018,991...76,084,044 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 decreases expression ISO Vincristine results in decreased expression of VAMP2 mRNA CTD PMID:23649840 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases expression ISO Vincristine results in increased expression of VASP mRNA CTD PMID:23649840 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO
EXP		 Vincristine results in increased expression of VCAM1 mRNA CTD PMID:20624997 PMID:23649840 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vdr vitamin D receptor affects response to substance ISO VDR gene polymorphism affects the susceptibility to Vincristine CTD PMID:15713801 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression EXP Vincristine results in decreased expression of VEGFA mRNA CTD PMID:20624997 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vezf1 vascular endothelial zinc finger 1 decreases expression ISO Vincristine results in decreased expression of VEZF1 mRNA CTD PMID:23649840 NCBI chr10:72,859,669...72,876,111
Ensembl chr10:72,859,877...72,876,111 		JBrowse link
G Vit vitrin increases response to substance ISO VIT mRNA results in increased susceptibility to Vincristine CTD PMID:25199881 NCBI chr 6:16,445,966...16,565,644
Ensembl chr 6:16,445,955...16,565,665 		JBrowse link
G Vps13a vacuolar protein sorting 13 homolog A decreases expression ISO Vincristine results in decreased expression of VPS13A mRNA CTD PMID:23649840 NCBI chr 1:213,901,999...214,128,638
Ensembl chr 1:213,901,999...214,128,555 		JBrowse link
G Vps13d vacuolar protein sorting 13 homolog D increases expression ISO Vincristine results in increased expression of VPS13D mRNA CTD PMID:23649840 NCBI chr 5:156,830,509...157,055,895
Ensembl chr 5:156,830,512...157,055,891 		JBrowse link
G Vps25 vacuolar protein sorting 25 homolog decreases expression ISO Vincristine results in decreased expression of VPS25 mRNA CTD PMID:23649840 NCBI chr10:86,196,062...86,201,606
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Vps53 VPS53 subunit of GARP complex increases expression ISO Vincristine results in increased expression of VPS53 mRNA CTD PMID:23649840 NCBI chr10:60,919,820...61,038,674
Ensembl chr10:60,919,820...61,038,676 		JBrowse link
G Vps72 vacuolar protein sorting 72 homolog decreases expression ISO Vincristine results in decreased expression of VPS72 mRNA CTD PMID:23649840 NCBI chr 2:182,678,594...182,690,185
Ensembl chr 2:182,678,609...182,690,182 		JBrowse link
G Vti1a vesicle transport through interaction with t-SNAREs 1A decreases expression ISO Vincristine results in decreased expression of VTI1A mRNA CTD PMID:23649840 NCBI chr 1:254,356,343...254,661,854
Ensembl chr 1:254,356,429...254,661,852 		JBrowse link
G Vwf von Willebrand factor increases expression EXP Vincristine results in increased expression of VWF mRNA CTD PMID:20624997 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wdhd1 WD repeat and HMG-box DNA binding protein 1 decreases expression ISO Vincristine results in decreased expression of WDHD1 mRNA CTD PMID:23649840 NCBI chr15:20,478,310...20,523,106
Ensembl chr15:20,489,291...20,523,096 		JBrowse link
G Wdr17 WD repeat domain 17 decreases expression ISO Vincristine results in decreased expression of WDR17 mRNA CTD PMID:23649840 NCBI chr16:37,059,923...37,191,125
Ensembl chr16:37,059,895...37,191,122 		JBrowse link
G Wdr33 WD repeat domain 33 decreases expression ISO Vincristine results in decreased expression of WDR33 mRNA CTD PMID:23649840 NCBI chr18:23,432,233...23,535,460
Ensembl chr18:23,432,191...23,468,597 		JBrowse link
G Wdr72 WD repeat domain 72 decreases expression ISO Vincristine results in decreased expression of WDR72 mRNA CTD PMID:23649840 NCBI chr 8:74,838,338...75,020,938
Ensembl chr 8:74,838,318...75,018,229 		JBrowse link
G Wdr76 WD repeat domain 76 decreases expression ISO Vincristine results in decreased expression of WDR76 mRNA CTD PMID:23649840 NCBI chr 3:108,456,784...108,491,528
Ensembl chr 3:108,456,815...108,490,840 		JBrowse link
G Wdr90 WD repeat domain 90 decreases expression ISO Vincristine results in decreased expression of WDR90 mRNA CTD PMID:23649840 NCBI chr10:14,864,672...14,881,285
Ensembl chr10:14,864,670...14,881,292 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression ISO Vincristine results in decreased expression of WEE1 mRNA CTD PMID:23649840 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 increases expression ISO Vincristine results in increased expression of WNK1 mRNA CTD PMID:23649840 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
G Wsb1 WD repeat and SOCS box-containing 1 decreases expression ISO Vincristine results in decreased expression of WSB1 mRNA CTD PMID:23649840 NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019 		JBrowse link
G Xirp2 xin actin-binding repeat containing 2 decreases expression ISO Vincristine results in decreased expression of XIRP2 mRNA CTD PMID:23649840 NCBI chr 3:52,126,213...52,213,094
Ensembl chr 3:51,870,092...52,213,091 		JBrowse link
G Xpnpep3 X-prolyl aminopeptidase 3 increases expression ISO Vincristine results in increased expression of XPNPEP3 mRNA CTD PMID:23649840 NCBI chr 7:112,926,154...112,978,793
Ensembl chr 7:112,926,248...112,974,878 		JBrowse link
G Ypel5 yippee-like 5 increases expression ISO Vincristine results in increased expression of YPEL5 mRNA CTD PMID:23649840 NCBI chr 6:22,656,284...22,671,741
Ensembl chr 6:22,656,285...22,671,691 		JBrowse link
G Ythdc2 YTH N6-methyladenosine RNA binding protein C2 decreases expression ISO Vincristine results in decreased expression of YTHDC2 mRNA CTD PMID:23649840 NCBI chr18:37,266,559...37,331,681
Ensembl chr18:37,265,836...37,331,023 		JBrowse link
G Ythdf3 YTH N6-methyladenosine RNA binding protein F3 increases expression ISO Vincristine results in increased expression of YTHDF3 mRNA CTD PMID:23649840 NCBI chr 2:98,350,304...98,384,608
Ensembl chr 2:98,350,588...98,384,606 		JBrowse link
G Zbtb10 zinc finger and BTB domain containing 10 increases expression ISO Vincristine results in increased expression of ZBTB10 mRNA CTD PMID:23649840 NCBI chr 2:92,475,254...92,509,892
Ensembl chr 2:92,479,014...92,512,515 		JBrowse link
G Zbtb14 zinc finger and BTB domain containing 14 decreases expression ISO Vincristine results in decreased expression of ZBTB14 mRNA CTD PMID:23649840 NCBI chr 9:109,333,440...109,338,646
Ensembl chr 9:109,331,028...109,338,632 		JBrowse link
G Zbtb24 zinc finger and BTB domain containing 24 decreases expression ISO Vincristine results in decreased expression of ZBTB24 mRNA CTD PMID:23649840 NCBI chr20:44,943,302...44,965,329
Ensembl chr20:44,947,297...44,963,963 		JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A increases expression ISO Vincristine results in increased expression of ZC3H12A mRNA CTD PMID:23649840 NCBI chr 5:137,376,562...137,385,351
Ensembl chr 5:137,376,564...137,385,351 		JBrowse link
G Zcchc2 zinc finger CCHC-type containing 2 decreases expression ISO Vincristine results in decreased expression of ZCCHC2 mRNA CTD PMID:23649840 NCBI chr13:22,118,677...22,193,626
Ensembl chr13:22,119,568...22,166,373 		JBrowse link
G Zfp207 zinc finger protein 207 decreases expression
increases expression		 ISO Vincristine results in decreased expression of ZNF207 mRNA
Vincristine results in increased expression of ZNF207 mRNA		 CTD PMID:23649840 NCBI chr10:65,385,807...65,398,086
Ensembl chr10:65,385,740...65,397,386 		JBrowse link
G Zfp395 zinc finger protein 395 decreases expression ISO Vincristine results in decreased expression of ZNF395 mRNA CTD PMID:23649840 NCBI chr15:39,581,603...39,621,911
Ensembl chr15:39,608,080...39,619,950 		JBrowse link
G Zfp503 zinc finger protein 503 decreases expression ISO Vincristine results in decreased expression of ZNF503 mRNA CTD PMID:23649840 NCBI chr15:2,313,060...2,316,848
Ensembl chr15:2,313,060...2,316,848 		JBrowse link
G Zfp638 zinc finger protein 638 increases expression ISO Vincristine results in increased expression of ZNF638 mRNA CTD PMID:23649840 NCBI chr 4:116,355,934...116,475,051
Ensembl chr 4:116,402,428...116,479,845 		JBrowse link
G Zfp652 zinc finger protein 652 decreases expression ISO Vincristine results in decreased expression of ZNF652 mRNA CTD PMID:23649840 NCBI chr10:80,626,555...80,706,397
Ensembl chr10:80,649,400...80,698,674 		JBrowse link
G Zfp672 zinc finger protein 672 decreases expression ISO Vincristine results in decreased expression of ZNF672 mRNA CTD PMID:23649840 NCBI chr10:42,496,558...42,512,134
Ensembl chr10:42,495,476...42,504,852 		JBrowse link
G Zfp691 zinc finger protein 691 decreases expression ISO Vincristine results in decreased expression of ZNF691 mRNA CTD PMID:23649840 NCBI chr 5:132,780,259...132,784,954
Ensembl chr 5:132,780,181...132,785,000 		JBrowse link
G Zfp692 zinc finger protein 692 decreases expression ISO Vincristine results in decreased expression of ZNF692 mRNA CTD PMID:23649840 NCBI chr10:42,484,576...42,496,573
Ensembl chr10:42,488,588...42,496,018 		JBrowse link
G Zfp709 zinc finger protein 709 decreases expression ISO Vincristine results in decreased expression of ZNF443 mRNA CTD PMID:23649840 NCBI chr16:17,907,599...17,920,047
Ensembl chr16:17,909,641...17,919,700 		JBrowse link
G Zfp830 zinc finger protein 830 decreases expression ISO Vincristine results in decreased expression of ZNF830 mRNA CTD PMID:23649840 NCBI chr10:67,701,340...67,702,804
Ensembl chr10:67,701,073...67,704,523 		JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 increases expression ISO Vincristine results in increased expression of ZFYVE16 mRNA CTD PMID:23649840 NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990 		JBrowse link
G Zmat3 zinc finger, matrin type 3 increases expression ISO Vincristine results in increased expression of ZMAT3 mRNA CTD PMID:23649840 NCBI chr 2:115,106,046...115,136,888
Ensembl chr 2:115,106,966...115,136,863 		JBrowse link
G Zmiz2 zinc finger, MIZ-type containing 2 increases expression ISO Vincristine results in increased expression of ZMIZ2 mRNA CTD PMID:23649840 NCBI chr14:81,251,391...81,267,936
Ensembl chr14:81,251,417...81,267,936 		JBrowse link
G Zmynd8 zinc finger, MYND-type containing 8 increases expression ISO Vincristine results in increased expression of ZMYND8 mRNA CTD PMID:23649840 NCBI chr 3:154,528,917...154,629,532
Ensembl chr 3:154,529,043...154,628,463 		JBrowse link
G Znfx1 zinc finger, NFX1-type containing 1 increases expression ISO Vincristine results in increased expression of ZNFX1 mRNA CTD PMID:23649840 NCBI chr 3:155,764,073...155,791,777
Ensembl chr 3:155,764,980...155,821,242 		JBrowse link
G Znrf2 zinc and ring finger 2 decreases expression ISO Vincristine results in decreased expression of ZNRF2 mRNA CTD PMID:23649840 NCBI chr 4:83,950,406...84,032,676
Ensembl chr 4:83,949,309...84,027,818 		JBrowse link
vindesine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions
decreases expression		 ISO Tamoxifen promotes the reaction [Vindesine results in decreased expression of BAX mRNA] CTD PMID:19757172 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression		 ISO Tamoxifen promotes the reaction [Vindesine results in increased expression of BCL2 mRNA] CTD PMID:19757172 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Ngf nerve growth factor decreases response to substance EXP Vindesine results in decreased susceptibility to NGF protein CTD PMID:9524088 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
vinorelbine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 multiple interactions ISO [pifithrin co-treated with vinorelbine] results in increased cleavage of and results in increased activity of CASP3 protein
[Cisplatin co-treated with vinorelbine] results in increased activity of CASP3 protein		 CTD PMID:18516295 PMID:21544650 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions ISO [Cisplatin co-treated with vinorelbine] results in decreased expression of CASP7 mRNA CTD PMID:21544650 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Cd40lg CD40 ligand multiple interactions ISO [Cisplatin co-treated with vinorelbine] results in decreased expression of CD40LG mRNA CTD PMID:21544650 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression ISO vinorelbine results in decreased expression of CDKN2A protein CTD PMID:17904787 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Epcam epithelial cell adhesion molecule multiple interactions
increases expression		 ISO [vinorelbine co-treated with Cisplatin] results in increased expression of EPCAM protein
vinorelbine results in increased expression of EPCAM protein		 CTD PMID:12695858 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Cisplatin co-treated with vinorelbine] results in increased expression of FAS protein CTD PMID:21544650 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions ISO [Cisplatin co-treated with vinorelbine] results in decreased expression of FASL mRNA CTD PMID:21544650 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Cisplatin co-treated with vinorelbine] results in decreased expression of IL10 mRNA CTD PMID:21544650 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il7 interleukin 7 multiple interactions ISO [Cisplatin co-treated with vinorelbine] results in increased expression of IL7 protein CTD PMID:21544650 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Krt18 keratin 18 increases expression
increases metabolic processing		 ISO vinorelbine results in increased expression of KRT18 protein
vinorelbine results in increased metabolism of KRT18 protein		 CTD PMID:16685278 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Lhx4 LIM homeobox 4 multiple interactions ISO [Cisplatin co-treated with vinorelbine] results in decreased expression of LHX4 mRNA CTD PMID:21544650 NCBI chr13:67,877,109...67,917,219
Ensembl chr13:67,877,109...67,927,003 		JBrowse link
G Npm1 nucleophosmin 1 decreases response to substance ISO NPM1 protein results in decreased susceptibility to vinorelbine CTD PMID:24736981 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO vinorelbine inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Pak5 p21 (RAC1) activated kinase 5 multiple interactions ISO [Cisplatin co-treated with Vinorelbine] results in decreased expression of PAK5 mRNA CTD PMID:21544650 NCBI chr 3:123,395,678...123,703,967
Ensembl chr 3:123,396,497...123,703,930 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa decreases expression ISO vinorelbine results in decreased expression of PROC protein CTD PMID:10475134 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO vinorelbine results in decreased expression of PTGS2 protein CTD PMID:17904787 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rbm17 RNA binding motif protein 17 decreases response to substance ISO RBM17 protein results in decreased susceptibility to vinorelbine CTD PMID:16061639 NCBI chr17:66,937,140...66,954,034
Ensembl chr17:66,937,140...66,954,014 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 affects response to substance ISO SLC29A1 protein affects the susceptibility to vinorelbine CTD PMID:18452103 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO Vinorelbine results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [Cisplatin co-treated with vinorelbine] results in decreased expression of TNF mRNA CTD PMID:21544650 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions ISO [Cisplatin co-treated with vinorelbine] results in decreased expression of TRAF1 mRNA CTD PMID:21544650 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
yohimbine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO Yohimbine analog results in increased expression of ABCB1 mRNA CTD PMID:7476894 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCB4 mRNA CTD PMID:28843594 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC2 mRNA CTD PMID:28843594 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCC3 mRNA CTD PMID:28843594 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Actg1 actin, gamma 1 increases expression EXP Yohimbine results in increased expression of ACTG1 mRNA CTD PMID:21983523 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 decreases expression EXP Yohimbine results in decreased expression of ADAM9 mRNA CTD PMID:21983523 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 increases expression EXP Yohimbine results in increased expression of ADAMTS4 mRNA CTD PMID:21983523 NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065 		JBrowse link
G Adra2a adrenoceptor alpha 2A multiple interactions ISO
EXP		 Yohimbine inhibits the reaction [Brimonidine Tartrate promotes the reaction [Phenylephrine binds to and results in increased activity of ADRA2A protein]]; Yohimbine inhibits the reaction [Norepinephrine binds to and results in increased activity of ADRA2A protein]
Yohimbine binds to and results in decreased activity of ADRA2A protein		 CTD PMID:8397342 PMID:10742289 PMID:17666864 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adrb1 adrenoceptor beta 1 multiple interactions EXP [Imipramine co-treated with Yohimbine] results in decreased activity of ADRB1 protein CTD PMID:2868116 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ALDOA mRNA CTD PMID:28843594 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of AVPR1A mRNA CTD PMID:28843594 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of BHMT mRNA CTD PMID:28843594 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Calu calumenin increases expression EXP Yohimbine results in increased expression of CALU mRNA CTD PMID:21983523 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593 		JBrowse link
G Cat catalase multiple interactions EXP Yohimbine inhibits the reaction [[COL2A1 protein co-treated with Adjuvants, Immunologic co-treated with Freund's Adjuvant] results in decreased activity of CAT protein] CTD PMID:27028940 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CCNG1 mRNA CTD PMID:28843594 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CD36 mRNA CTD PMID:28843594 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cdc14b cell division cycle 14B multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CDC14B mRNA CTD PMID:28843594 NCBI chr17:844,686...934,787
Ensembl chr17:844,685...933,235 		JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CEMIP2 mRNA CTD PMID:28843594 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760 		JBrowse link
G Clic1 chloride intracellular channel 1 decreases expression EXP Yohimbine results in decreased expression of CLIC1 mRNA CTD PMID:21983523 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712 		JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP Yohimbine inhibits the reaction [[COL2A1 protein co-treated with Adjuvants, Immunologic co-treated with Freund's Adjuvant] results in decreased activity of CAT protein]; Yohimbine inhibits the reaction [[COL2A1 protein co-treated with Adjuvants, Immunologic co-treated with Freund's Adjuvant] results in increased expression of PTGS2 protein]; Yohimbine inhibits the reaction [[COL2A1 protein co-treated with Adjuvants, Immunologic co-treated with Freund's Adjuvant] results in increased expression of RELA protein]; Yohimbine inhibits the reaction [[COL2A1 protein co-treated with Adjuvants, Immunologic co-treated with Freund's Adjuvant] results in increased expression of TNF protein] CTD PMID:27028940 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Crh corticotropin releasing hormone multiple interactions EXP Yohimbine affects the reaction [Norepinephrine affects the expression of and affects the secretion of CRH protein]; Yohimbine inhibits the reaction [Nitroprusside results in increased expression of and results in increased secretion of CRH protein] CTD PMID:3497798 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of CXCL12 mRNA CTD PMID:28843594 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of CYP1A2 mRNA CTD PMID:28843594 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects metabolic processing
affects response to substance		 ISO CYP2D6 gene polymorphism affects the metabolism of Yohimbine
CYP2D6 protein affects the susceptibility to Yohimbine		 CTD PMID:15289791 PMID:34027562 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
affects metabolic processing		 ISO Yohimbine analog inhibits the reaction [Calcitriol results in increased expression of CYP3A4 protein]
CYP3A4 gene polymorphism affects the metabolism of Yohimbine		 CTD PMID:15289791 PMID:29782822 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of FASN mRNA CTD PMID:28843594 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of GCLC mRNA CTD PMID:28843594 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of GSR mRNA CTD PMID:28843594 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions ISO [Yohimbine co-treated with Cocaine] affects the reaction [HTR2A protein results in increased susceptibility to 4-iodo-2,5-dimethoxyphenylisopropylamine] CTD PMID:8392199 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of LPL mRNA CTD PMID:28843594 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lss lanosterol synthase multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] affects the expression of LSS mRNA CTD PMID:28843594 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Maoa monoamine oxidase A decreases activity ISO Yohimbine results in decreased activity of MAOA protein CTD PMID:28302559 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Mir101a microRNA 101a multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of MIR101A mRNA CTD PMID:28843594 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir122 microRNA 122 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] affects the expression of MIR122 mRNA CTD PMID:28843594 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir192 microRNA 192 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of MIR192 mRNA CTD PMID:28843594 NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055 		JBrowse link
G Mlxipl MLX interacting protein-like multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of MLXIPL mRNA CTD PMID:28843594 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112 		JBrowse link
G Myct1 myc target 1 increases expression EXP Yohimbine results in increased expression of MYCT1 mRNA CTD PMID:21983523 NCBI chr 1:42,018,137...42,029,410
Ensembl chr 1:42,018,137...42,029,410 		JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression EXP Yohimbine results in increased expression of NFKBIZ mRNA CTD PMID:21983523 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Yohimbine inhibits the reaction [endotoxin, Escherichia coli results in increased expression of NOS2 protein]; Yohimbine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:17637181 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Npy neuropeptide Y multiple interactions EXP Yohimbine inhibits the reaction [Clonidine results in decreased expression of NPY mRNA] CTD PMID:1878751 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of NQO1 mRNA CTD PMID:28843594 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrip3 nuclear receptor interacting protein 3 increases expression EXP Yohimbine results in increased expression of NRIP3 mRNA CTD PMID:21983523 NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of PLA2G12A mRNA CTD PMID:28843594 NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740 		JBrowse link
G Pomc proopiomelanocortin multiple interactions EXP Yohimbine inhibits the reaction [Ethanol results in increased secretion of POMC protein] CTD PMID:22236039 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prl prolactin increases expression ISO Yohimbine results in increased expression of PRL protein CTD PMID:3153710 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Yohimbine inhibits the reaction [[COL2A1 protein co-treated with Adjuvants, Immunologic co-treated with Freund's Adjuvant] results in increased expression of PTGS2 protein]; Yohimbine inhibits the reaction [endotoxin, Escherichia coli results in increased expression of PTGS2 protein]; Yohimbine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] CTD PMID:17637181 PMID:27028940 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Yohimbine inhibits the reaction [[COL2A1 protein co-treated with Adjuvants, Immunologic co-treated with Freund's Adjuvant] results in increased expression of RELA protein] CTD PMID:27028940 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ren renin multiple interactions
increases expression		 EXP Chlorisondamine inhibits the reaction [Yohimbine results in increased expression of REN protein]; Indomethacin inhibits the reaction [Yohimbine results in increased expression of REN protein]; Meclofenamic Acid inhibits the reaction [Yohimbine results in increased expression of REN protein]; Propranolol inhibits the reaction [Yohimbine results in increased expression of REN protein] CTD PMID:6323192 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of SCD1 mRNA CTD PMID:28843594 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Thrsp thyroid hormone responsive multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in decreased expression of THRSP mRNA CTD PMID:28843594 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075 		JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP Yohimbine inhibits the reaction [[COL2A1 protein co-treated with Adjuvants, Immunologic co-treated with Freund's Adjuvant] results in increased expression of TNF protein] CTD PMID:27028940 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of TXNRD1 mRNA CTD PMID:28843594 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    role 19839
      biological role 19858
        biochemical role 19566
          metabolite 19533
            alkaloid 8015
              indole alkaloid 1978
                terpenoid indole alkaloid 1501
                  14,15-epoxyemindole-SB 0
                  dehydrosecodine 0
                  emindole SB 0
                  hemiterpenoid indole alkaloid + 28
                  monoterpenoid indole alkaloid + 1483
                  paxilline 13
                  suaveolindole 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19890
    subatomic particle 19867
      composite particle 19888
        hadron 19888
          baryon 19888
            nucleon 19867
              atomic nucleus 19888
                atom 19888
                  main group element atom 19806
                    p-block element atom 19806
                      carbon group element atom 19746
                        carbon atom 19743
                          organic molecular entity 19743
                            heteroorganic entity 19502
                              organonitrogen compound 18845
                                alkaloid 8015
                                  indole alkaloid 1978
                                    terpenoid indole alkaloid 1501
                                      14,15-epoxyemindole-SB 0
                                      dehydrosecodine 0
                                      emindole SB 0
                                      hemiterpenoid indole alkaloid + 28
                                      monoterpenoid indole alkaloid + 1483
                                      paxilline 13
                                      suaveolindole 0
paths to the root