P4ha1 (prolyl 4-hydroxylase subunit alpha 1)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| FTP Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: P4ha1 (prolyl 4-hydroxylase subunit alpha 1) Rattus norvegicus

Analyze

Symbol:

P4ha1

Name:

prolyl 4-hydroxylase subunit alpha 1

RGD ID:

621000

Description:

Predicted to contribute to procollagen-proline 4-dioxygenase activity. Predicted to be involved in collagen fibril organization and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to localize to mitochondrion and procollagen-proline 4-dioxygenase complex. Orthologous to human P4HA1 (prolyl 4-hydroxylase subunit alpha 1); PARTICIPATES IN arginine and proline metabolic pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

4-PH alpha-1; PHalphaI; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide; procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I; procollagen-proline,2-oxoglutarate-4-dioxygenase subunit alpha-1; prolyl 4-hydroxylase alpha subunit; prolyl 4-hydroxylase subunit alpha-1; prolyl 4-hydroxylase, alpha polypeptide I

Orthologs:

Homo sapiens (human) : P4HA1 (prolyl 4-hydroxylase subunit alpha 1) HGNC Alliance
Mus musculus (house mouse) : P4ha1 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide) MGI Alliance
Chinchilla lanigera (long-tailed chinchilla) : P4ha1 (prolyl 4-hydroxylase subunit alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : P4HA1 (prolyl 4-hydroxylase subunit alpha 1)
Canis lupus familiaris (dog) : P4HA1 (prolyl 4-hydroxylase subunit alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : P4ha1 (prolyl 4-hydroxylase subunit alpha 1)
Sus scrofa (pig) : P4HA1 (prolyl 4-hydroxylase subunit alpha 1)
Chlorocebus sabaeus (African green monkey) : P4HA1 (prolyl 4-hydroxylase subunit alpha 1)
Heterocephalus glaber (naked mole-rat) : P4ha1 (prolyl 4-hydroxylase subunit alpha 1)

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, PhylomeDB
Mus musculus (house mouse):	P4ha1 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide)	HGNC	EggNOG, NCBI, OMA, HomoloGene, Inparanoid, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	P4ha1 (prolyl 4-hydroxylase subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	P4ha1 (prolyl 4-hydroxylase subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	P4ha1 (prolyl 4-hydroxylase subunit alpha 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	P4HA1 (prolyl 4-hydroxylase subunit alpha 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	P4ha1 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	p4ha1a (prolyl 4-hydroxylase, alpha polypeptide I a)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	p4ha1b (prolyl 4-hydroxylase, alpha polypeptide I b)	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG18233	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG18234	Alliance	DIOPT (Ensembl Compara\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG31016	Alliance	DIOPT (Ensembl Compara\|OMA\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG32199	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG32201	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG34345	Alliance	DIOPT (Ensembl Compara\|OMA\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG4174	Alliance	DIOPT (Ensembl Compara\|OMA\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG9698	Alliance	DIOPT (Ensembl Compara\|OMA\|PhylomeDB)
Drosophila melanogaster (fruit fly):	PH4alphaNE1	Alliance	DIOPT (Ensembl Compara\|OMA\|PhylomeDB)
Drosophila melanogaster (fruit fly):	PH4alphaNE3	Alliance	DIOPT (Ensembl Compara\|OMA\|PhylomeDB)
Drosophila melanogaster (fruit fly):	PH4alphaPV	Alliance	DIOPT (Ensembl Compara\|OMA\|PhylomeDB)
Drosophila melanogaster (fruit fly):	PH4alphaEFB	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Caenorhabditis elegans (roundworm):	phy-2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	20	28,920,616 - 28,972,576 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	28,920,616 - 28,971,966 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	30,726,604 - 30,776,891 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	20	28,745,570 - 28,795,338 (+)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3-chloropropane-1,2-diol (EXP)

3H-1,2-dithiole-3-thione (EXP)

adefovir pivoxil (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

benzoates (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

bleomycin A5 (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

chloroacetaldehyde (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

clodronic acid (ISO)

cobalt dichloride (EXP,ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

desferrioxamine B (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

dioxygen (ISO)

disodium selenite (ISO)

diuron (EXP)

doxorubicin (ISO)

endosulfan (EXP)

ethanol (ISO)

fenofibrate (EXP)

ferric ammonium citrate (ISO)

folic acid (ISO)

formaldehyde (ISO)

gamma-hexachlorocyclohexane (EXP)

glucose (ISO)

hydrogen sulfide (ISO)

ifosfamide (ISO)

iron atom (EXP)

iron(0) (EXP)

ketamine (EXP)

leflunomide (EXP)

lipopolysaccharide (EXP)

mercury dichloride (EXP)

methamphetamine (EXP)

methapyrilene (ISO)

methotrexate (ISO)

methylmercury chloride (ISO)

mitoxantrone (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP)

N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine (EXP)

nickel dichloride (EXP,ISO)

nitric oxide (ISO)

oxaliplatin (EXP,ISO)

ozone (EXP,ISO)

paracetamol (ISO)

phenobarbital (EXP,ISO)

phenylephrine (EXP)

pirinixic acid (ISO)

propiconazole (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

ranitidine (EXP)

resveratrol (ISO)

rotenone (EXP)

S-butyl-DL-homocysteine (S,R)-sulfoximine (ISO)

SCH 23390 (EXP)

Se-methyl-L-selenocysteine (ISO)

Se-methylselenocysteine (ISO)

sodium fluoride (ISO)

sunitinib (ISO)

tamoxifen (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (ISO)

thimerosal (ISO)

titanium dioxide (ISO)

tolcapone (EXP)

topotecan (EXP)

valdecoxib (EXP)

valproic acid (ISO)

vincristine (ISO)

vorinostat (ISO)

zinc atom (EXP)

zinc dichloride (ISO)

zinc(0) (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

collagen fibril organization (ISO)

oxidation-reduction process (IEA)

peptidyl-proline hydroxylation to 4-hydroxy-L-proline (IBA,ISO,TAS)

Cellular Component

endoplasmic reticulum (IBA,ISO)

endoplasmic reticulum lumen (IEA)

intracellular membrane-bounded organelle (ISO)

mitochondrion (IEA,ISO)

procollagen-proline 4-dioxygenase complex (ISO)

Molecular Function

identical protein binding (ISO)

iron ion binding (IEA)

L-ascorbic acid binding (IEA)

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (IEA)

procollagen-proline 4-dioxygenase activity (IBA,ISO,TAS)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

arginine and proline metabolic pathway (IEA)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	Hopkinson I, etal., Gene 1994 Nov 18;149(2):391-2.
4.	MGD data from the GO Consortium
5.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	Pipeline to import KEGG annotations from KEGG into RGD
7.	RGD automated data pipeline
8.	RGD automated import pipeline for gene-chemical interactions
9.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10.	Takahashi S, etal., Biochim Biophys Acta 2002 Apr 12;1574(3):354-8.

Additional References at PubMed

PMID:7753822	PMID:10799490	PMID:15489334	PMID:17135260	PMID:19946888	PMID:24207127

Genomics

Comparative Map Data

P4ha1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	20	28,920,616 - 28,972,576 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	28,920,616 - 28,971,966 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	20	30,726,604 - 30,776,891 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	20	28,745,570 - 28,795,338 (+)	NCBI		Celera
Cytogenetic Map	20	q11	NCBI

P4HA1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	10	73,007,217 - 73,096,974 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	10	73,007,217 - 73,096,866 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	10	74,766,975 - 74,856,732 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	74,436,981 - 74,526,630 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	10	74,436,987 - 74,526,614	NCBI
Celera	10	68,052,119 - 68,141,888 (-)	NCBI
Cytogenetic Map	10	q22.1	NCBI
HuRef	10	68,760,779 - 68,850,247 (-)	NCBI		HuRef
CHM1_1	10	75,048,716 - 75,138,475 (-)	NCBI		CHM1_1

P4ha1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	59,159,019 - 59,209,126 (+)	NCBI
GRCm38	10	59,323,197 - 59,373,304 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	59,323,296 - 59,373,304 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	58,786,044 - 58,836,052 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	10	58,718,730 - 58,767,701 (+)	NCBI			mm8
Celera	10	60,423,571 - 60,473,579 (+)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI

P4ha1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955437	18,604,525 - 18,668,800 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955437	18,604,525 - 18,668,800 (+)	NCBI	ChiLan1.0	ChiLan1.0

P4HA1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	10	72,017,493 - 72,106,083 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	72,017,500 - 72,106,083 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	10	69,554,722 - 69,643,765 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

P4HA1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	4	23,601,636 - 23,677,762 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	4	23,600,399 - 23,677,820 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

P4ha1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936521	5,981,205 - 6,045,195 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

P4HA1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	75,825,140 - 75,918,917 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	75,827,207 - 75,919,121 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	81,892,533 - 82,002,926 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

P4HA1
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	9	58,178,461 - 58,259,802 (+)	Ensembl
ChlSab1.1	9	58,178,350 - 58,259,303 (+)	NCBI

P4ha1
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624754	6,707,429 - 6,802,333 (-)	NCBI

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
6893685	Bw111	Body weight QTL 111	2.7	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	20	1	33300419	Rat
9590252	Scort12	Serum corticosterone level QTL 12	20.46	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	20	1	37550487	Rat
7411668	Foco32	Food consumption QTL 32	8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	1	37550487	Rat
2305926	Iddm37	Insulin dependent diabetes mellitus QTL 37	6		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	20	2018654	47018654	Rat
1641915	Colcr9	Colorectal carcinoma resistance QTL 9	2.97	0.0024	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	20	2999707	47999707	Rat
1598816	Memor12	Memory QTL 12	2.4		exploratory behavior trait (VT:0010471)	average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)	20	4108956	49108956	Rat
4889870	Pur30	Proteinuria QTL 30	19	0.005	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	20	8654341	30991290	Rat
9590092	Insglur9	Insulin/glucose ratio QTL 9	18.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	20	13834309	56205956	Rat
7411652	Foco24	Food consumption QTL 24		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	20	13834309	56205956	Rat
2317880	Alcrsp25	Alcohol response QTL 25	2.3		response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	20	17827096	56205956	Rat
4889610	Pancm3	Pancreatic morphology QTL 3	3.75	0.001	pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	20	18872150	49108956	Rat
2303626	Vencon10	Ventilatory control QTL 10		0.001	respiration trait (VT:0001943)	respiration rate (CMO:0000289)	20	20858470	56205956	Rat
2303578	Gluco50	Glucose level QTL 50	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	20	26608843	56205956	Rat
2303587	Bw93	Body weight QTL 93	13		body mass (VT:0001259)	body weight (CMO:0000012)	20	26608843	56205956	Rat
2300188	Bmd68	Bone mineral density QTL 68	6.4	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	20	26608843	56205956	Rat
1331747	Hrtrt16	Heart rate QTL 16	3.163		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	20	26712323	56205956	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	134
Count of miRNA genes:	109
Interacting mature miRNAs:	116
Transcripts:	ENSRNOT00000070897
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1	43	44	28	19	28	8	11	74	35	40	11	8
Low	2		13	13		13					1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_172062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006256425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AABR07044973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01100869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01100870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF197928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X78949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000070897 ⟹ ENSRNOP00000064405

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	20	28,920,616 - 28,971,966 (+)	Ensembl

RefSeq Acc Id:

NM_172062 ⟹ NP_742059

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	28,920,616 - 28,971,984 (+)	NCBI
Rnor_5.0	20	30,726,604 - 30,776,891 (+)	NCBI
Celera	20	28,745,570 - 28,795,338 (+)	RGD

Sequence:

show sequence

GTGACTGAGCGCACGTAGCGAGAGCTGTGGCCGCCCCGTTCTCGGCGCGCCGGCGCGGCTGGGG
ACTATAAAAGGCTCCTCTGGCTCCCTCTGCTGCCCAGTCGCACCGCCAGCAGGCTGAGCGCGGC
AGGGAGCTACCTAGTGGGGACTACAGGCGACAGGACCGACCCGAGCCGAGCTGTCGCCTTCCTC
ACGGCCCGCTATCCAGGTGTGTGAACCTGTGGGGTGCTCCAAGATGATCTGGGGTGTATTAATG
ATGGGGATTCTACTTCCTCAGTGTTCAGCCCATCCAGGCTTTTTTACTTCAATTGGTCAGATGA
CTGACTTGATCCATAATGAGAAAGACCTGGTGACGTCACTAAAAGATTACATTAAAGCAGAAGA
GGACAAGTTAGAGCAAATCAAAAAATGGGCAGAGAAGTTAGACCGGCTAACAAGTACAGCAACA
AAAGATCCAGAAGGGTTTGTCGGACACCCTGTAAATGCATTCAAGTTAATGAAACGTCTGAACA
CCGAGTGGAGTGAGTTGGAGAATCTGATCCTCAAGGATATGTCAGATGGCTTCATCTCTAACCT
GACCATTCAGAGGCAGTACTTCCCTAACGACGAAGACCAGGTTGGGGCTGCAAAAGCTTTGTTT
CGTCTGCAAGACACCTACAACCTAGACACGAATACCATCTCGAAGGGCAATCTTCCAGGAGTGA
AACACAAGTCTTTTCTAACAGCTGAGGACTGCTTTGAGTTGGGCAAAGTGGCCTATACAGAAGC
AGATTATTACCACACAGAACTCTGGATGGAGCAGGCTCTGATGCAGCTGGAGGAGGGAGAGATG
TCTACTGTAGACAAAGTCTCGGTTCTAGATTATTTGAGCTATGCAGTGTACCAGCAGGGTGACC
TGGATAAGGCACTTCTGCTTACAAAGAAACTTCTTGAACTAGATCCTGAACACCAGAGAGCCAA
TGGTAACTTAGTATATTTTGAGTATATAATGAGTAAAGAAAAAGATGCCAATAAGTCTGCTTCG
GGTGACCAGTCTGATCAGAAAACTACACCAAAGAAAAAGGGGATTGCTGTGGACTACCTGCCAG
AGAGACAGAAGTACGAAATGCTGTGCCGTGGGGAGGGTATCAAAATGACTCCTCGGAGACAAAA
AAGGCTGTTCTGCCGCTACCATGATGGAAACCGGAATCCTAAATTTATCCTGGCCCCAGCCAAG
CAGGAGGATGAGTGGGACAAGCCTCGCATCATTCGTTTCCATGACATCATCTCAGATGCCGAGA
TTGAGATCGTCAAAGATTTAGCAAAGCCCAGGCTGAGCCGAGCTACAGTACATGACCCTGAGAC
TGGGAAATTGACCACAGCACAGTACAGAGTATCTAAGAGTGCTTGGCTGTCTGGCTATGAAGAT
CCTGTGGTGTCTCGAATTAATATGAGAATACAAGATCTCACAGGACTGGATGTTTCCACGGCAG
AGGAATTACAGGTAGCAAATTATGGAGTTGGAGGACAGTATGAACCCCATTTTGACTTTGCCAG
GAAAGACGAGCCGGATGCTTTTAGAGAGCTTGGGACAGGAAATAGGATTGCCACGTGGCTCTTC
TACATGAGTGATGTGTCTGCTGGAGGCGCTACTGTTTTTCCTGAAGTGGGAGCCAGTGTTTGGC
CCAAAAAAGGCACTGCTGTCTTCTGGTACAATCTGTTTGCCAGTGGAGAAGGAGATTACAGTAC
ACGGCACGCAGCCTGTCCTGTGCTAGTGGGAAACAAATGGGTATCCAACAAATGGCTCCATGAA
CGTGGACAGGAATTTCGAAGGCCGTGTACCCTGTCAGAATTGGAATGACAACCAGGCTTCCCGT
GGCTCCTCTCGTCCTCTAACGCACCAGGCATGATCGCTGACTGTAACATTCAGAAGTTTACAGC
TGACTAACACTCCATGATTAATTCGGCCGTGAACCCCATCCCATGTTTCATCTGTGGACAATCA
CTTATTTTTGTGAATTTTTTTAAATTAACACTCAGTCACCACATTGTGTAAAACTTATGGTTCA
GTTATCACAGGATACAGGATATTTAAAATGAGGAACCTAGTTCTGTTGTTTAAAAGAGCTTTTT
GGTTGATTTAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006256424 ⟹ XP_006256486

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	28,920,631 - 28,972,576 (+)	NCBI
Rnor_5.0	20	30,726,604 - 30,776,891 (+)	NCBI

Sequence:

show sequence

TAGCGAGAGCTGTGGCCGCCCCGTTCTCGGCGCGCCGGCGCGGCTGGGGACTATAAAAGGCTCC
TCTGGCTCCCTCTGCTGCCCAGTCGCACCGCCAGCAGGCTGAGCGCGGCAGGGAGCTACCTAGT
GGGGACTACAGGCGACAGGACCGACCCGAGCCGAGCTGTCGCCTTCCTCACGGCCCGCTATCCA
GGTGGATAAAGCTGTTTCCATTGTTAGACTGAAGTGAGTTCTATTTTGAAATAAAGCTGACACT
TTGATGAAAGGATTGGGCATTTTGTCACTTTGTAACCCAGGTGTGTGAACCTGTGGGGTGCTCC
AAGATGATCTGGGGTGTATTAATGATGGGGATTCTACTTCCTCAGTGTTCAGCCCATCCAGGCT
TTTTTACTTCAATTGGTCAGATGACTGACTTGATCCATAATGAGAAAGACCTGGTGACGTCACT
AAAAGATTACATTAAAGCAGAAGAGGACAAGTTAGAGCAAATCAAAAAATGGGCAGAGAAGTTA
GACCGGCTAACAAGTACAGCAACAAAAGATCCAGAAGGGTTTGTCGGACACCCTGTAAATGCAT
TCAAGTTAATGAAACGTCTGAACACCGAGTGGAGTGAGTTGGAGAATCTGATCCTCAAGGATAT
GTCAGATGGCTTCATCTCTAACCTGACCATTCAGAGGCAGTACTTCCCTAACGACGAAGACCAG
GTTGGGGCTGCAAAAGCTTTGTTTCGTCTGCAAGACACCTACAACCTAGACACGAATACCATCT
CGAAGGGCAATCTTCCAGGAGTGAAACACAAGTCTTTTCTAACAGCTGAGGACTGCTTTGAGTT
GGGCAAAGTGGCCTATACAGAAGCAGATTATTACCACACAGAACTCTGGATGGAGCAGGCTCTG
ATGCAGCTGGAGGAGGGAGAGATGTCTACTGTAGACAAAGTCTCGGTTCTAGATTATTTGAGCT
ATGCAGTGTACCAGCAGGGTGACCTGGATAAGGCACTTCTGCTTACAAAGAAACTTCTTGAACT
AGATCCTGAACACCAGAGAGCCAATGGTAACTTAGTATATTTTGAGTATATAATGAGTAAAGAA
AAAGATGCCAATAAGTCTGCTTCGGGTGACCAGTCTGATCAGAAAACTACACCAAAGAAAAAGG
GGATTGCTGTGGACTACCTGCCAGAGAGACAGAAGTACGAAATGCTGTGCCGTGGGGAGGGTAT
CAAAATGACTCCTCGGAGACAAAAAAGGCTGTTCTGCCGCTACCATGATGGAAACCGGAATCCT
AAATTTATCCTGGCCCCAGCCAAGCAGGAGGATGAGTGGGACAAGCCTCGCATCATTCGTTTCC
ATGACATCATCTCAGATGCCGAGATTGAGATCGTCAAAGATTTAGCAAAGCCCAGGCTGAGCCG
AGCTACAGTACATGACCCTGAGACTGGGAAATTGACCACAGCACAGTACAGAGTATCTAAGAGT
GCTTGGCTGTCTGGCTATGAAGATCCTGTGGTGTCTCGAATTAATATGAGAATACAAGATCTCA
CAGGACTGGATGTTTCCACGGCAGAGGAATTACAGGTAGCAAATTATGGAGTTGGAGGACAGTA
TGAACCCCATTTTGACTTTGCCAGGAAAGACGAGCCGGATGCTTTTAGAGAGCTTGGGACAGGA
AATAGGATTGCCACGTGGCTCTTCTACATGAGTGATGTGTCTGCTGGAGGCGCTACTGTTTTTC
CTGAAGTGGGAGCCAGTGTTTGGCCCAAAAAAGGCACTGCTGTCTTCTGGTACAATCTGTTTGC
CAGTGGAGAAGGAGATTACAGTACACGGCACGCAGCCTGTCCTGTGCTAGTGGGAAACAAATGG
GTATCCAACAAATGGCTCCATGAACGTGGACAGGAATTTCGAAGGCCGTGTACCCTGTCAGAAT
TGGAATGACAACCAGGCTTCCCGTGGCTCCTCTCGTCCTCTAACGCACCAGGCATGATCGCTGA
CTGTAACATTCAGAAGTTTACAGCTGACTAACACTCCATGATTAATTCGGCCGTGAACCCCATC
CCATGTTTCATCTGTGGACAATCACTTATTTTTGTGAATTTTTTTAAATTAACACTCAGTCACC
ACATTGTGTAAAACTTATGGTTCAGTTATCACAGGATACAGGATATTTAAAATGAGGAACCTAG
TTCTGTTGTTTAAAAGAGCTTTTTGGTTGATTTAAAAAAAAAAAAAAAAAACGCGTCCAGTAGT
AAATCTCACCCATCTCAGGAGCTGGCGGACCGGGGAGGCTGCAGGTGGCGTGCAGATGCCTGTG
TACTGTTCTTCCTCCGCCACTGCGCTTTCTGGAGTGCCAAGCACTCGTAGCTAACTAGGGCTCA
GGCCCGTCCTAGGGTTTGCCCTCCGTCTACTCTTCCACATGCATAGTTCTTATATAAAGAAACT
CTTTATATCAAATCCCCCTCCTCACCACTGGTGAATTCAGCCGGTTTGAGAAATTACTTTGTTC
AAAAAGTCCTGCAGAACTGGCCTCATAACTAAATGCTCAGACGTAGACCTTTTCCTCAGTGACT
ATGGTGTCCAGAGACTGTTCCAAGTGCCACTCCCCTGCCGTGTATTCAGCTGCAGCAGGCGATG
ATGTTGGCTTTCTGACTAAATTCTGTGCCTTAGGAGACTGGGAGTAATGAAATGGACAGGTCCT
TGTAATGAGGGAGTTGGTTTTTAAAAAAAAATTTTTTATAAAAAGCCAAAATGTTTGTTTTTTC
CCATTCTGAAATGTGTTATGATAACAGTGACCTATTTATGATCTTAAATCTTTTTTAAAAAAAA
AAA

hide sequence

RefSeq Acc Id:

XM_006256425 ⟹ XP_006256487

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	28,920,622 - 28,972,576 (+)	NCBI
Rnor_5.0	20	30,726,604 - 30,776,891 (+)	NCBI

Sequence:

show sequence

GAGCGCACGTAGCGAGAGCTGTGGCCGCCCCGTTCTCGGCGCGCCGGCGCGGCTGGGGACTATA
AAAGGCTCCTCTGGCTCCCTCTGCTGCCCAGTCGCACCGCCAGCAGGCTGAGCGCGGCAGGGAG
CTACCTAGTGGGGACTACAGGCGACAGGACCGACCCGAGCCGAGCTGTCGCCTTCCTCACGGCC
CGCTATCCAGGTGTGTGAACCTGTGGGGTGCTCCAAGATGATCTGGGGTGTATTAATGATGGGG
ATTCTACTTCCTCAGTGTTCAGCCCATCCAGGCTTTTTTACTTCAATTGGTCAGATGACTGACT
TGATCCATAATGAGAAAGACCTGGTGACGTCACTAAAAGATTACATTAAAGCAGAAGAGGACAA
GTTAGAGCAAATCAAAAAATGGGCAGAGAAGTTAGACCGGCTAACAAGTACAGCAACAAAAGAT
CCAGAAGGGTTTGTCGGACACCCTGTAAATGCATTCAAGTTAATGAAACGTCTGAACACCGAGT
GGAGTGAGTTGGAGAATCTGATCCTCAAGGATATGTCAGATGGCTTCATCTCTAACCTGACCAT
TCAGAGGCAGTACTTCCCTAACGACGAAGACCAGGTTGGGGCTGCAAAAGCTTTGTTTCGTCTG
CAAGACACCTACAACCTAGACACGAATACCATCTCGAAGGGCAATCTTCCAGGAGTGAAACACA
AGTCTTTTCTAACAGCTGAGGACTGCTTTGAGTTGGGCAAAGTGGCCTATACAGAAGCAGATTA
TTACCACACAGAACTCTGGATGGAGCAGGCTCTGATGCAGCTGGAGGAGGGAGAGATGTCTACT
GTAGACAAAGTCTCGGTTCTAGATTATTTGAGCTATGCAGTGTACCAGCAGGGTGACCTGGATA
AGGCACTTCTGCTTACAAAGAAACTTCTTGAACTAGATCCTGAACACCAGAGAGCCAATGGTAA
CTTAGTATATTTTGAGTATATAATGAGTAAAGAAAAAGATGCCAATAAGTCTGCTTCGGGTGAC
CAGTCTGATCAGAAAACTACACCAAAGAAAAAGGGGATTGCTGTGGACTACCTGCCAGAGAGAC
AGAAGTACGAAATGCTGTGCCGTGGGGAGGGTATCAAAATGACTCCTCGGAGACAAAAAAGGCT
GTTCTGCCGCTACCATGATGGAAACCGGAATCCTAAATTTATCCTGGCCCCAGCCAAGCAGGAG
GATGAGTGGGACAAGCCTCGCATCATTCGTTTCCATGACATCATCTCAGATGCCGAGATTGAGA
TCGTCAAAGATTTAGCAAAGCCCAGGCTGAGGCGAGCCACCATTTCAAACCCAGTAACAGGAGC
CTTGGAGACGGTACATTACAGAATTAGCAAAAGTGCTTGGCTGTCTGGCTATGAAGATCCTGTG
GTGTCTCGAATTAATATGAGAATACAAGATCTCACAGGACTGGATGTTTCCACGGCAGAGGAAT
TACAGGTAGCAAATTATGGAGTTGGAGGACAGTATGAACCCCATTTTGACTTTGCCAGGAAAGA
CGAGCCGGATGCTTTTAGAGAGCTTGGGACAGGAAATAGGATTGCCACGTGGCTCTTCTACATG
AGTGATGTGTCTGCTGGAGGCGCTACTGTTTTTCCTGAAGTGGGAGCCAGTGTTTGGCCCAAAA
AAGGCACTGCTGTCTTCTGGTACAATCTGTTTGCCAGTGGAGAAGGAGATTACAGTACACGGCA
CGCAGCCTGTCCTGTGCTAGTGGGAAACAAATGGGTATCCAACAAATGGCTCCATGAACGTGGA
CAGGAATTTCGAAGGCCGTGTACCCTGTCAGAATTGGAATGACAACCAGGCTTCCCGTGGCTCC
TCTCGTCCTCTAACGCACCAGGCATGATCGCTGACTGTAACATTCAGAAGTTTACAGCTGACTA
ACACTCCATGATTAATTCGGCCGTGAACCCCATCCCATGTTTCATCTGTGGACAATCACTTATT
TTTGTGAATTTTTTTAAATTAACACTCAGTCACCACATTGTGTAAAACTTATGGTTCAGTTATC
ACAGGATACAGGATATTTAAAATGAGGAACCTAGTTCTGTTGTTTAAAAGAGCTTTTTGGTTGA
TTTAAAAAAAAAAAAAAAAAACGCGTCCAGTAGTAAATCTCACCCATCTCAGGAGCTGGCGGAC
CGGGGAGGCTGCAGGTGGCGTGCAGATGCCTGTGTACTGTTCTTCCTCCGCCACTGCGCTTTCT
GGAGTGCCAAGCACTCGTAGCTAACTAGGGCTCAGGCCCGTCCTAGGGTTTGCCCTCCGTCTAC
TCTTCCACATGCATAGTTCTTATATAAAGAAACTCTTTATATCAAATCCCCCTCCTCACCACTG
GTGAATTCAGCCGGTTTGAGAAATTACTTTGTTCAAAAAGTCCTGCAGAACTGGCCTCATAACT
AAATGCTCAGACGTAGACCTTTTCCTCAGTGACTATGGTGTCCAGAGACTGTTCCAAGTGCCAC
TCCCCTGCCGTGTATTCAGCTGCAGCAGGCGATGATGTTGGCTTTCTGACTAAATTCTGTGCCT
TAGGAGACTGGGAGTAATGAAATGGACAGGTCCTTGTAATGAGGGAGTTGGTTTTTAAAAAAAA
ATTTTTTATAAAAAGCCAAAATGTTTGTTTTTTCCCATTCTGAAATGTGTTATGATAACAGTGA
CCTATTTATGATCTTAAATCTTTTTTAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_742059	(Get FASTA)	NCBI Sequence Viewer
	XP_006256486	(Get FASTA)	NCBI Sequence Viewer
	XP_006256487	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH78703	(Get FASTA)	NCBI Sequence Viewer
	CAA55546	(Get FASTA)	NCBI Sequence Viewer
	EDL93076	(Get FASTA)	NCBI Sequence Viewer
	EDL93077	(Get FASTA)	NCBI Sequence Viewer
	P54001	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_742059 ⟸ NM_172062
- Peptide Label:	precursor
- UniProtKB:	P54001 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MIWGVLMMGILLPQCSAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLD RLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYFPNDEDQV GAAKALFRLQDTYNLDTNTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALM QLEEGEMSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEK DANKSASGDQSDQKTTPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPK FILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSA WLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGN RIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWV SNKWLHERGQEFRRPCTLSELE hide sequence

RefSeq Acc Id:

XP_006256487 ⟸ XM_006256425

- Peptide Label:

isoform X1

- Sequence:

show sequence

MIWGVLMMGILLPQCSAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLD
RLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYFPNDEDQV
GAAKALFRLQDTYNLDTNTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALM
QLEEGEMSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEK
DANKSASGDQSDQKTTPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPK
FILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLRRATISNPVTGALETVHYRISKSA
WLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGN
RIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWV
SNKWLHERGQEFRRPCTLSELE

hide sequence

RefSeq Acc Id:	XP_006256486 ⟸ XM_006256424
- Peptide Label:	isoform X2
- UniProtKB:	P54001 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MIWGVLMMGILLPQCSAHPGFFTSIGQMTDLIHNEKDLVTSLKDYIKAEEDKLEQIKKWAEKLD RLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLILKDMSDGFISNLTIQRQYFPNDEDQV GAAKALFRLQDTYNLDTNTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQALM QLEEGEMSTVDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLVYFEYIMSKEK DANKSASGDQSDQKTTPKKKGIAVDYLPERQKYEMLCRGEGIKMTPRRQKRLFCRYHDGNRNPK FILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSA WLSGYEDPVVSRINMRIQDLTGLDVSTAEELQVANYGVGGQYEPHFDFARKDEPDAFRELGTGN RIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWV SNKWLHERGQEFRRPCTLSELE hide sequence

RefSeq Acc Id:

ENSRNOP00000064405 ⟸ ENSRNOT00000070897

Protein Domains

Fe2OG dioxygenase

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701587

Promoter ID:

EPDNEW_R12111

Type:

multiple initiation site

Name:

P4ha1_1

Description:

prolyl 4-hydroxylase subunit alpha 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	20	28,920,711 - 28,920,771	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621000	AgrOrtholog
Ensembl Genes	ENSRNOG00000050655	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000064405	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000070897	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.40.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7115543	IMAGE-MGC_LOAD
InterPro	Oxoglu/Fe-dep_dioxygenase	UniProtKB/Swiss-Prot
	Pro_4_hyd_alph	UniProtKB/Swiss-Prot
	Pro_4_hyd_alph_N	UniProtKB/Swiss-Prot
	TPR-contain_dom	UniProtKB/Swiss-Prot
	TPR-like_helical_dom_sf	UniProtKB/Swiss-Prot
	TPR_repeat	UniProtKB/Swiss-Prot
KEGG Report	rno:64475	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93107	IMAGE-MGC_LOAD
NCBI Gene	64475	ENTREZGENE
Pfam	2OG-FeII_Oxy_3	UniProtKB/Swiss-Prot
	P4Ha_N	UniProtKB/Swiss-Prot
PhenoGen	P4ha1	PhenoGen
PROSITE	FE2OG_OXY	UniProtKB/Swiss-Prot
	TPR	UniProtKB/Swiss-Prot
	TPR_REGION	UniProtKB/Swiss-Prot
SMART	P4Hc	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48452	UniProtKB/Swiss-Prot
UniGene	Rn.8531	ENTREZGENE
UniProt	P4HA1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q6AZ74	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-02-03	P4ha1	prolyl 4-hydroxylase subunit alpha 1	P4ha1	prolyl 4-hydroxylase, alpha polypeptide I	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-04-23	P4ha1	prolyl 4-hydroxylase, alpha polypeptide I	P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-24	P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I	P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	P4ha1	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide		prolyl 4-hydroxylase alpha subunit	Name updated	1299863	APPROVED
2002-08-07	P4ha1	prolyl 4-hydroxylase alpha subunit			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - KEGG (archival)