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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3637
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Scn5a
Name: sodium voltage-gated channel alpha subunit 5
Acc ID: CHEBI:132668
Term: icajine
Definition: A monoterpenoid indole alkaloid with formula C22H24N2O3, originallly isolated from the leaves of Strychnos icaja.
Chemical ID: MESH:C438914
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Scn5amultiple interactionsISORGD:7312556480464CTDicajine binds to and results in decreased activity of SCN5A protein

PMID:21616062
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