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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61898
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Maoa
Name: monoamine oxidase A
Acc ID: CHEBI:10093
Term: yohimbine
Definition: An indole alkaloid with alpha2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina.
Chemical ID: MESH:D015016
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases activityISORGD:7357516480464CTDYohimbine results in decreased activity of MAOA protein

PMID:28302559
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.