Gmppb (GDP-mannose pyrophosphorylase B) - Rat Genome Database

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Gene: Gmppb (GDP-mannose pyrophosphorylase B) Rattus norvegicus
Analyze
Symbol: Gmppb
Name: GDP-mannose pyrophosphorylase B
RGD ID: 1560458
Description: Predicted to enable mannose-1-phosphate guanylyltransferase activity. Predicted to be involved in GDP-mannose biosynthetic process and protein glycosylation. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2T and congenital muscular dystrophy-dystroglycanopathy A14. Orthologous to human GMPPB (GDP-mannose pyrophosphorylase B); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC363145; mannose-1-phosphate guanyltransferase beta; RGD1560458; similar to GDP-mannose pyrophosphorylase B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28108,737,429 - 108,767,286 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl8108,693,060 - 108,767,286 (+)Ensembl
Rnor_6.08116,826,251 - 116,856,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,826,680 - 116,856,159 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,180,562 - 116,210,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,317,165 - 113,346,646 (+)NCBIRGSC3.4rn4RGSC3.4
Celera8108,042,518 - 108,071,499 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GMPPB-Associated Dystroglycanopathy: Emerging Common Variants with Phenotype Correlation. Jensen BS, etal., Hum Mutat. 2015 Dec;36(12):1159-63. doi: 10.1002/humu.22898. Epub 2015 Sep 23.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11082198   PMID:18614015   PMID:23376485   PMID:23768512  


Genomics

Comparative Map Data
Gmppb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28108,737,429 - 108,767,286 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl8108,693,060 - 108,767,286 (+)Ensembl
Rnor_6.08116,826,251 - 116,856,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8116,826,680 - 116,856,159 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08116,180,562 - 116,210,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,317,165 - 113,346,646 (+)NCBIRGSC3.4rn4RGSC3.4
Celera8108,042,518 - 108,071,499 (+)NCBICelera
Cytogenetic Map8q32NCBI
GMPPB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38349,719,916 - 49,723,951 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl349,716,844 - 49,723,973 (-)EnsemblGRCh38hg38GRCh38
GRCh37349,757,349 - 49,761,384 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,733,936 - 49,736,388 (-)NCBINCBI36hg18NCBI36
Celera349,723,623 - 49,726,075 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,817,885 - 49,820,383 (-)NCBIHuRef
CHM1_1349,710,967 - 49,713,465 (-)NCBICHM1_1
T2T-CHM13v2.0349,749,202 - 49,753,237 (-)NCBI
Gmppb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,926,438 - 107,929,120 (+)NCBIGRCm39mm39
GRCm39 Ensembl9107,926,441 - 107,930,000 (+)Ensembl
GRCm389108,049,239 - 108,051,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,049,242 - 108,052,801 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,951,621 - 107,954,267 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,907,410 - 107,909,802 (+)NCBImm8
Celera9107,659,146 - 107,661,786 (+)NCBICelera
Cytogenetic Map9F1NCBI
Gmppb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,622,605 - 1,624,900 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,622,605 - 1,624,900 (-)NCBIChiLan1.0ChiLan1.0
GMPPB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,889,479 - 50,891,969 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,889,479 - 50,891,969 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,653,638 - 49,656,135 (-)NCBIMhudiblu_PPA_v0panPan3
GMPPB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12039,550,799 - 39,553,045 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2039,550,799 - 39,553,045 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2039,471,723 - 39,473,969 (+)NCBI
ROS_Cfam_1.02039,908,319 - 39,910,564 (+)NCBI
ROS_Cfam_1.0 Ensembl2039,908,072 - 39,911,799 (+)Ensembl
UMICH_Zoey_3.12039,275,391 - 39,277,636 (+)NCBI
UNSW_CanFamBas_1.02039,678,760 - 39,681,006 (+)NCBI
UU_Cfam_GSD_1.02039,958,590 - 39,960,836 (+)NCBI
Gmppb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560264,574,309 - 64,577,997 (-)NCBI
SpeTri2.0NW_0049365291,336,002 - 1,338,615 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GMPPB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,246,468 - 32,253,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,246,471 - 32,253,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,425,664 - 35,432,367 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GMPPB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,116,497 - 11,118,980 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2211,116,752 - 11,118,926 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041155,881,479 - 155,885,552 (+)NCBIVero_WHO_p1.0
Gmppb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247303,645,768 - 3,648,165 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247303,645,768 - 3,648,157 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH127749  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,736,738 - 108,736,923 (+)MAPPERmRatBN7.2
Rnor_6.08116,825,613 - 116,825,797NCBIRnor6.0
Rnor_5.08116,179,935 - 116,180,119UniSTSRnor5.0
RGSC_v3.48113,316,098 - 113,316,282UniSTSRGSC3.4
Celera8108,041,451 - 108,041,635UniSTS
RH 3.4 Map81118.6UniSTS
Cytogenetic Map8q32UniSTS
RH129768  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,744,055 - 108,744,231 (+)MAPPERmRatBN7.2
Rnor_6.08116,832,930 - 116,833,105NCBIRnor6.0
Rnor_5.08116,187,252 - 116,187,427UniSTSRnor5.0
RGSC_v3.48113,323,415 - 113,323,590UniSTSRGSC3.4
Celera8108,048,768 - 108,048,943UniSTS
Cytogenetic Map8q32UniSTS
RH139593  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,741,840 - 108,742,025 (+)MAPPERmRatBN7.2
Rnor_6.08116,830,715 - 116,830,899NCBIRnor6.0
Rnor_5.08116,185,037 - 116,185,221UniSTSRnor5.0
RGSC_v3.48113,321,200 - 113,321,384UniSTSRGSC3.4
Celera8108,046,553 - 108,046,737UniSTS
RH 3.4 Map81118.6UniSTS
Cytogenetic Map8q32UniSTS
RH140652  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,738,658 - 108,739,067 (+)MAPPERmRatBN7.2
Rnor_6.08116,827,533 - 116,827,941NCBIRnor6.0
Rnor_5.08116,181,855 - 116,182,263UniSTSRnor5.0
RGSC_v3.48113,318,018 - 113,318,426UniSTSRGSC3.4
Celera8108,043,371 - 108,043,779UniSTS
RH 3.4 Map81118.4UniSTS
Cytogenetic Map8q32UniSTS
BE119447  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,742,655 - 108,742,810 (+)MAPPERmRatBN7.2
Rnor_6.08116,831,530 - 116,831,684NCBIRnor6.0
Rnor_5.08116,185,852 - 116,186,006UniSTSRnor5.0
RGSC_v3.48113,322,015 - 113,322,169UniSTSRGSC3.4
Celera8108,047,368 - 108,047,522UniSTS
RH 3.4 Map81119.2UniSTS
Cytogenetic Map8q32UniSTS
MARC_17265-17266:1024683815:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,758,229 - 108,758,740 (+)MAPPERmRatBN7.2
Rnor_6.08116,847,103 - 116,847,613NCBIRnor6.0
Rnor_5.08116,201,425 - 116,201,935UniSTSRnor5.0
RGSC_v3.48113,337,588 - 113,338,098UniSTSRGSC3.4
Celera8108,062,960 - 108,063,470UniSTS
Cytogenetic Map8q32UniSTS
Amigo3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28108,742,329 - 108,743,321 (+)MAPPERmRatBN7.2
Rnor_6.08116,831,204 - 116,832,195NCBIRnor6.0
Rnor_5.08116,185,526 - 116,186,517UniSTSRnor5.0
RGSC_v3.48113,321,689 - 113,322,680UniSTSRGSC3.4
Celera8108,047,042 - 108,048,033UniSTS
Cytogenetic Map8q32UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)846531639119088624Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088624Rat
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
631217Activ1Activity QTL 115.9voluntary movement trait (VT:0003491)number of photobeam interruptions in an experimental apparatus (CMO:0001517)8102370617108923645Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:82
Interacting mature miRNAs:99
Transcripts:ENSRNOT00000026854
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 43 36 18 36 62 30 32 11
Low 17 14 5 1 5 8 11 12 5 9 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000026854   ⟹   ENSRNOP00000026854
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8108,693,060 - 108,767,286 (+)Ensembl
Rnor_6.0 Ensembl8116,826,680 - 116,856,159 (+)Ensembl
RefSeq Acc Id: NM_001108781   ⟹   NP_001102251
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28108,737,806 - 108,767,286 (+)NCBI
Rnor_6.08116,826,680 - 116,856,159 (+)NCBI
Rnor_5.08116,180,562 - 116,210,240 (+)NCBI
RGSC_v3.48113,317,165 - 113,346,646 (+)RGD
Celera8108,042,518 - 108,071,499 (+)RGD
Sequence:
RefSeq Acc Id: XM_006243811   ⟹   XP_006243873
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28108,737,429 - 108,740,437 (+)NCBI
Rnor_6.08116,826,251 - 116,829,308 (+)NCBI
Rnor_5.08116,180,562 - 116,210,240 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001102251 (Get FASTA)   NCBI Sequence Viewer  
  XP_006243873 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL77196 (Get FASTA)   NCBI Sequence Viewer  
  EDL77197 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001102251   ⟸   NM_001108781
- UniProtKB: D4A746 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243873   ⟸   XM_006243811
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000026854   ⟸   ENSRNOT00000026854

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A746-F1-model_v2 AlphaFold D4A746 1-360 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696287
Promoter ID:EPDNEW_R6812
Type:initiation region
Name:Gmppb_1
Description:GDP-mannose pyrophosphorylase B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08116,826,705 - 116,826,765EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_6.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
8 116848493 116848494 A C snv FHL/EurMcwi (MCW)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560458 AgrOrtholog
BioCyc Gene G2FUF-29161 BioCyc
Ensembl Genes ENSRNOG00000037229 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000026854.6 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000026854.6 UniProtKB/TrEMBL
Gene3D-CATH 3.90.550.10 UniProtKB/TrEMBL
InterPro GMPPB_N UniProtKB/TrEMBL
  Hexapep_transf UniProtKB/TrEMBL
  Hexapep_transf_CS UniProtKB/TrEMBL
  NTP_transferase UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/TrEMBL
KEGG Report rno:363145 UniProtKB/TrEMBL
NCBI Gene 363145 ENTREZGENE
Pfam Hexapep UniProtKB/TrEMBL
  NTP_transferase UniProtKB/TrEMBL
PhenoGen Gmppb PhenoGen
PROSITE HEXAPEP_TRANSFERASES UniProtKB/TrEMBL
Superfamily-SCOP SSF53448 UniProtKB/TrEMBL
UniProt D4A746 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Gmppb  GDP-mannose pyrophosphorylase B   Gmppb_predicted  GDP-mannose pyrophosphorylase B (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Gmppb_predicted  GDP-mannose pyrophosphorylase B (predicted)  RGD1560458_predicted  similar to GDP-mannose pyrophosphorylase B (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1560458_predicted  similar to GDP-mannose pyrophosphorylase B (predicted)  LOC363145  similar to GDP-mannose pyrophosphorylase B  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC363145  similar to GDP-mannose pyrophosphorylase B      Symbol and Name status set to provisional 70820 PROVISIONAL