GMPPB (GDP-mannose pyrophosphorylase B) - Rat Genome Database
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Gene: GMPPB (GDP-mannose pyrophosphorylase B) Sus scrofa
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Symbol: GMPPB
Name: GDP-mannose pyrophosphorylase B
RGD ID: 14161001
Description: ENCODES a protein that exhibits mannose-1-phosphate guanylyltransferase activity; INVOLVED IN GDP-mannose biosynthetic process (ortholog); PARTICIPATES IN fructose and mannose metabolic pathway; fructosuria pathway; hereditary fructose intolerance syndrome pathway; ASSOCIATED WITH autosomal recessive limb-girdle muscular dystrophy type 2T (ortholog); congenital muscular dystrophy-dystroglycanopathy A14 (ortholog); congenital myasthenic syndrome (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GDP-mannose pyrophosphorylase 37-kDa subunit; GTP-mannose-1-phosphate guanylyltransferase beta; mannose-1-phosphate guanyltransferase beta
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,246,468 - 32,253,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,246,471 - 32,253,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,425,664 - 35,432,367 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:11082198   PMID:14681463   PMID:17145712  


Genomics

Comparative Map Data
GMPPB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1332,246,468 - 32,253,148 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11332,246,471 - 32,253,162 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21335,425,664 - 35,432,367 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GMPPB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl349,716,844 - 49,723,973 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl349,716,844 - 49,723,951 (-)EnsemblGRCh38hg38GRCh38
GRCh38349,719,916 - 49,723,951 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,757,349 - 49,761,384 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,733,936 - 49,736,388 (-)NCBINCBI36hg18NCBI36
Celera349,723,623 - 49,726,075 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,817,885 - 49,820,383 (-)NCBIHuRef
CHM1_1349,710,967 - 49,713,465 (-)NCBICHM1_1
Gmppb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399107,926,438 - 107,929,120 (+)NCBIGRCm39mm39
GRCm39 Ensembl9107,926,441 - 107,930,000 (+)Ensembl
GRCm389108,049,239 - 108,051,923 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,049,242 - 108,052,801 (+)EnsemblGRCm38mm10GRCm38
MGSCv379107,951,621 - 107,954,267 (+)NCBIGRCm37mm9NCBIm37
MGSCv369107,907,410 - 107,909,802 (+)NCBImm8
Celera9107,659,146 - 107,661,786 (+)NCBICelera
Cytogenetic Map9F1NCBI
Gmppb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28108,737,429 - 108,767,286 (+)NCBI
Rnor_6.0 Ensembl8116,826,680 - 116,856,159 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08116,826,251 - 116,856,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08116,180,562 - 116,210,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48113,317,165 - 113,346,646 (+)NCBIRGSC3.4rn4RGSC3.4
Celera8108,042,518 - 108,071,499 (+)NCBICelera
Cytogenetic Map8q32NCBI
Gmppb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555321,622,605 - 1,624,900 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555321,622,605 - 1,624,900 (-)NCBIChiLan1.0ChiLan1.0
GMPPB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1350,889,479 - 50,891,969 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl350,889,479 - 50,891,969 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0349,653,638 - 49,656,135 (-)NCBIMhudiblu_PPA_v0panPan3
GMPPB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2039,550,799 - 39,553,045 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12039,550,799 - 39,553,045 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gmppb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365291,336,002 - 1,338,615 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GMPPB
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,116,497 - 11,118,980 (-)NCBI
ChlSab1.1 Ensembl2211,116,752 - 11,118,926 (-)Ensembl
Gmppb
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247303,645,768 - 3,648,157 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 1 1 1
Low 9 4 3 4 2 23 2 2 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000012466   ⟹   ENSSSCP00000012141
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1332,246,470 - 32,253,131 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000039517   ⟹   ENSSSCP00000058925
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1332,246,468 - 32,253,134 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000040043   ⟹   ENSSSCP00000041325
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1332,246,490 - 32,253,148 (-)Ensembl
RefSeq Acc Id: NM_001244541   ⟹   NP_001231470
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11332,250,712 - 32,253,155 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005669546   ⟹   XP_005669603
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11332,246,471 - 32,253,162 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001231470 (Get FASTA)   NCBI Sequence Viewer  
  XP_005669603 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein P0C5I2 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005669603   ⟸   XM_005669546
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001231470   ⟸   NM_001244541
- Sequence:
RefSeq Acc Id: ENSSSCP00000041325   ⟸   ENSSSCT00000040043
RefSeq Acc Id: ENSSSCP00000058925   ⟸   ENSSSCT00000039517
RefSeq Acc Id: ENSSSCP00000012141   ⟸   ENSSSCT00000012466
Protein Domains
Ig-like   NTP_transferase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011389 Ensembl, UniProtKB/TrEMBL
  ENSSSCG00070003063 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000012141 UniProtKB/TrEMBL
  ENSSSCP00000041325 UniProtKB/TrEMBL
  ENSSSCP00000058925 UniProtKB/TrEMBL
  ENSSSCP00070004687 UniProtKB/TrEMBL
  ENSSSCP00070004690 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012466 UniProtKB/TrEMBL
  ENSSSCT00000039517 UniProtKB/TrEMBL
  ENSSSCT00000040043 UniProtKB/TrEMBL
  ENSSSCT00070005747 UniProtKB/TrEMBL
  ENSSSCT00070005750 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
  3.90.550.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AMIGO UniProtKB/TrEMBL
  AMIGO3 UniProtKB/TrEMBL
  Hexapep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hexapep_transf_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  NTP_transferase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide-diphossugar_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:100513376 UniProtKB/TrEMBL
NCBI Gene GMPPB ENTREZGENE
PANTHER PTHR24368 UniProtKB/TrEMBL
  PTHR24368:SF62 UniProtKB/TrEMBL
Pfam Hexapep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_8 UniProtKB/TrEMBL
  NTP_transferase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE HEXAPEP_TRANSFERASES UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  LRR_TYP UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF53448 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A4X1SQL6_PIG UniProtKB/TrEMBL
  A0A4X1SRI5_PIG UniProtKB/TrEMBL
  F1SPR5_PIG UniProtKB/TrEMBL
  GMPPB_PIG UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A0A287ABZ1 UniProtKB/TrEMBL